Association of intraperitoneal ceftriaxone, intravenous gentamicin and oral metronidazole in the treatment of an abdominal abscess and peritonitis in a horse: Case report
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.11606/issn.1678-4456.bjvras.2020.166204 http://hdl.handle.net/11449/228848 |
Resumo: | Medical management of abdominal abscesses in horses requires prolonged antibiotic therapy and presents varied success rates. A 6-year-old male horse with a history of colic and multiple abdominal punctures to relieve gas was attended. At admission, tachycardia, tachypnea, hyperthermia, mucosal congestion, dehydration, and rigid gait were observed. The association of physical examination, laboratory and ultrasonographic findings allowed the diagnoses of peritonitis and abdominal abscess. Supporting treatment plus broad spectrum antibiotic therapy was performed: daily intraperitoneal ceftriaxone (25 mg/kg, 7 days); daily intravenous gentamicin (6.6 mg/kg, 7 days); per os metronidazole three times a day (15 mg/kg 12 days), followed by the same dose twice a day (15 mg/kg 33 days), totaling 45 days of treatment. Plasma fibrinogen and ultrasonographic examination were the most effective tools to evaluate abscess evolution. There was normalization of the physical examination 24 h after beginning the treatment, consecutive regression of the nucleated cell count in the peritoneal fluid, and regression of plasma fibrinogen and size of the abscess. On the 10th treatment day, the animal was discharged from the hospital, maintaining oral therapy with metronidazole every 12 h (15 mg / kg). When the animal returned on the 30th day, an abscess size regression was observed. However, there was no resolution, and therapy with metronidazole was maintained. On the 45th day of treatment, a new hospital evaluation was performed, where the abscess resolved, and metronidazole was suspended. It is highlighted that the therapeutic association used in the treatment of abdominal infection and abscess resulted in a rapid clinical response. |
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Association of intraperitoneal ceftriaxone, intravenous gentamicin and oral metronidazole in the treatment of an abdominal abscess and peritonitis in a horse: Case reportAssociação da ceftriaxona intraperitoneal, gentamicina intravenosa e do metronidazol oral no tratamento de abscesso abdominal e peritonite em equino: Relato de um casoAbdominal infectionFibrinogenHorsesIntraperitoneal routeSonographyMedical management of abdominal abscesses in horses requires prolonged antibiotic therapy and presents varied success rates. A 6-year-old male horse with a history of colic and multiple abdominal punctures to relieve gas was attended. At admission, tachycardia, tachypnea, hyperthermia, mucosal congestion, dehydration, and rigid gait were observed. The association of physical examination, laboratory and ultrasonographic findings allowed the diagnoses of peritonitis and abdominal abscess. Supporting treatment plus broad spectrum antibiotic therapy was performed: daily intraperitoneal ceftriaxone (25 mg/kg, 7 days); daily intravenous gentamicin (6.6 mg/kg, 7 days); per os metronidazole three times a day (15 mg/kg 12 days), followed by the same dose twice a day (15 mg/kg 33 days), totaling 45 days of treatment. Plasma fibrinogen and ultrasonographic examination were the most effective tools to evaluate abscess evolution. There was normalization of the physical examination 24 h after beginning the treatment, consecutive regression of the nucleated cell count in the peritoneal fluid, and regression of plasma fibrinogen and size of the abscess. On the 10th treatment day, the animal was discharged from the hospital, maintaining oral therapy with metronidazole every 12 h (15 mg / kg). When the animal returned on the 30th day, an abscess size regression was observed. However, there was no resolution, and therapy with metronidazole was maintained. On the 45th day of treatment, a new hospital evaluation was performed, where the abscess resolved, and metronidazole was suspended. It is highlighted that the therapeutic association used in the treatment of abdominal infection and abscess resulted in a rapid clinical response.Universidade Estadual Paulista Faculdade de Medicina Veterinária e Zootecnia Departamento de Cirurgia Veterinária e Reprodução AnimalUniversidade Estadual Paulista Faculdade de Medicina Veterinária e Zootecnia Departamento de Clínica VeterináriaUniversidade Estadual Paulista Faculdade de Medicina Veterinária e Zootecnia Departamento de Cirurgia Veterinária e Reprodução AnimalUniversidade Estadual Paulista Faculdade de Medicina Veterinária e Zootecnia Departamento de Clínica VeterináriaUniversidade Estadual Paulista (UNESP)Alonso, Juliana de Moura [UNESP]Ávila, Alice Ribeiro [UNESP]Apolonio, Emanuel Vitor Pereira [UNESP]Dos Santos, Bruna [UNESP]Alves, Ana Liz Garcia [UNESP]Watanabe, Marcos Jun [UNESP]Rodrigues, Celso Antônio [UNESP]Hussni, Carlos Alberto [UNESP]2022-04-29T08:28:59Z2022-04-29T08:28:59Z2020-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1-9http://dx.doi.org/10.11606/issn.1678-4456.bjvras.2020.166204Brazilian Journal of Veterinary Research and Animal Science, v. 57, n. 2, p. 1-9, 2020.1678-44561413-9596http://hdl.handle.net/11449/22884810.11606/issn.1678-4456.bjvras.2020.1662042-s2.0-85090722497Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBrazilian Journal of Veterinary Research and Animal Scienceinfo:eu-repo/semantics/openAccess2024-09-09T14:05:52Zoai:repositorio.unesp.br:11449/228848Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-09T14:05:52Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Association of intraperitoneal ceftriaxone, intravenous gentamicin and oral metronidazole in the treatment of an abdominal abscess and peritonitis in a horse: Case report Associação da ceftriaxona intraperitoneal, gentamicina intravenosa e do metronidazol oral no tratamento de abscesso abdominal e peritonite em equino: Relato de um caso |
title |
Association of intraperitoneal ceftriaxone, intravenous gentamicin and oral metronidazole in the treatment of an abdominal abscess and peritonitis in a horse: Case report |
spellingShingle |
Association of intraperitoneal ceftriaxone, intravenous gentamicin and oral metronidazole in the treatment of an abdominal abscess and peritonitis in a horse: Case report Alonso, Juliana de Moura [UNESP] Abdominal infection Fibrinogen Horses Intraperitoneal route Sonography |
title_short |
Association of intraperitoneal ceftriaxone, intravenous gentamicin and oral metronidazole in the treatment of an abdominal abscess and peritonitis in a horse: Case report |
title_full |
Association of intraperitoneal ceftriaxone, intravenous gentamicin and oral metronidazole in the treatment of an abdominal abscess and peritonitis in a horse: Case report |
title_fullStr |
Association of intraperitoneal ceftriaxone, intravenous gentamicin and oral metronidazole in the treatment of an abdominal abscess and peritonitis in a horse: Case report |
title_full_unstemmed |
Association of intraperitoneal ceftriaxone, intravenous gentamicin and oral metronidazole in the treatment of an abdominal abscess and peritonitis in a horse: Case report |
title_sort |
Association of intraperitoneal ceftriaxone, intravenous gentamicin and oral metronidazole in the treatment of an abdominal abscess and peritonitis in a horse: Case report |
author |
Alonso, Juliana de Moura [UNESP] |
author_facet |
Alonso, Juliana de Moura [UNESP] Ávila, Alice Ribeiro [UNESP] Apolonio, Emanuel Vitor Pereira [UNESP] Dos Santos, Bruna [UNESP] Alves, Ana Liz Garcia [UNESP] Watanabe, Marcos Jun [UNESP] Rodrigues, Celso Antônio [UNESP] Hussni, Carlos Alberto [UNESP] |
author_role |
author |
author2 |
Ávila, Alice Ribeiro [UNESP] Apolonio, Emanuel Vitor Pereira [UNESP] Dos Santos, Bruna [UNESP] Alves, Ana Liz Garcia [UNESP] Watanabe, Marcos Jun [UNESP] Rodrigues, Celso Antônio [UNESP] Hussni, Carlos Alberto [UNESP] |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Alonso, Juliana de Moura [UNESP] Ávila, Alice Ribeiro [UNESP] Apolonio, Emanuel Vitor Pereira [UNESP] Dos Santos, Bruna [UNESP] Alves, Ana Liz Garcia [UNESP] Watanabe, Marcos Jun [UNESP] Rodrigues, Celso Antônio [UNESP] Hussni, Carlos Alberto [UNESP] |
dc.subject.por.fl_str_mv |
Abdominal infection Fibrinogen Horses Intraperitoneal route Sonography |
topic |
Abdominal infection Fibrinogen Horses Intraperitoneal route Sonography |
description |
Medical management of abdominal abscesses in horses requires prolonged antibiotic therapy and presents varied success rates. A 6-year-old male horse with a history of colic and multiple abdominal punctures to relieve gas was attended. At admission, tachycardia, tachypnea, hyperthermia, mucosal congestion, dehydration, and rigid gait were observed. The association of physical examination, laboratory and ultrasonographic findings allowed the diagnoses of peritonitis and abdominal abscess. Supporting treatment plus broad spectrum antibiotic therapy was performed: daily intraperitoneal ceftriaxone (25 mg/kg, 7 days); daily intravenous gentamicin (6.6 mg/kg, 7 days); per os metronidazole three times a day (15 mg/kg 12 days), followed by the same dose twice a day (15 mg/kg 33 days), totaling 45 days of treatment. Plasma fibrinogen and ultrasonographic examination were the most effective tools to evaluate abscess evolution. There was normalization of the physical examination 24 h after beginning the treatment, consecutive regression of the nucleated cell count in the peritoneal fluid, and regression of plasma fibrinogen and size of the abscess. On the 10th treatment day, the animal was discharged from the hospital, maintaining oral therapy with metronidazole every 12 h (15 mg / kg). When the animal returned on the 30th day, an abscess size regression was observed. However, there was no resolution, and therapy with metronidazole was maintained. On the 45th day of treatment, a new hospital evaluation was performed, where the abscess resolved, and metronidazole was suspended. It is highlighted that the therapeutic association used in the treatment of abdominal infection and abscess resulted in a rapid clinical response. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-01-01 2022-04-29T08:28:59Z 2022-04-29T08:28:59Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.11606/issn.1678-4456.bjvras.2020.166204 Brazilian Journal of Veterinary Research and Animal Science, v. 57, n. 2, p. 1-9, 2020. 1678-4456 1413-9596 http://hdl.handle.net/11449/228848 10.11606/issn.1678-4456.bjvras.2020.166204 2-s2.0-85090722497 |
url |
http://dx.doi.org/10.11606/issn.1678-4456.bjvras.2020.166204 http://hdl.handle.net/11449/228848 |
identifier_str_mv |
Brazilian Journal of Veterinary Research and Animal Science, v. 57, n. 2, p. 1-9, 2020. 1678-4456 1413-9596 10.11606/issn.1678-4456.bjvras.2020.166204 2-s2.0-85090722497 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Brazilian Journal of Veterinary Research and Animal Science |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
1-9 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
repositoriounesp@unesp.br |
_version_ |
1810021341410099200 |