Fluorescence visualization efficacy for detecting oral lesions more prone to be dysplastic and potentially malignant disorders: a pilot study
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.pdpdt.2016.10.010 http://hdl.handle.net/11449/162718 |
Resumo: | Background: To analyze the efficacy of fluorescence visualization in early detection of oral early neoplastic processes when used by an inexperienced and an adept oral examiner. Methods: A dental student and an expert professional in oral diagnosis examined 15 randomly selected patients using conventional oral examination and fluorescence visualization searching for early signs of epithelial dysplasia and oral potentially malignant disorders. Patients detected with oral lesions in any of examinations were submitted to incisional biopsy for definitive diagnosis. Results: Taking histopathologic analysis as Gold Standard, sensitivity, specificity, positive and negative predictive values and accuracy of inexperienced examiner for detecting both epithelium dysplasia and oral potentially malignant disorders increased when using fluorescence visualization compared to conventional white light examination, matching the same values found for expert professional in oral diagnosis. Furthermore, it was possible to observe discrete increase in the efficacy of expert professional's examination when using fluorescence visualization. Conclusion: This study indicates fluorescence visualization is capable of improve inexperienced professionals' efficacy for early detecting oral lesions more prone to be dysplastic and oral potentially malignant disorders. (C) 2016 Elsevier B.V. All rights reserved. |
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Fluorescence visualization efficacy for detecting oral lesions more prone to be dysplastic and potentially malignant disorders: a pilot studyOptical imagingDiagnosisOralEarly diagnosisMouth neoplasmsBackground: To analyze the efficacy of fluorescence visualization in early detection of oral early neoplastic processes when used by an inexperienced and an adept oral examiner. Methods: A dental student and an expert professional in oral diagnosis examined 15 randomly selected patients using conventional oral examination and fluorescence visualization searching for early signs of epithelial dysplasia and oral potentially malignant disorders. Patients detected with oral lesions in any of examinations were submitted to incisional biopsy for definitive diagnosis. Results: Taking histopathologic analysis as Gold Standard, sensitivity, specificity, positive and negative predictive values and accuracy of inexperienced examiner for detecting both epithelium dysplasia and oral potentially malignant disorders increased when using fluorescence visualization compared to conventional white light examination, matching the same values found for expert professional in oral diagnosis. Furthermore, it was possible to observe discrete increase in the efficacy of expert professional's examination when using fluorescence visualization. Conclusion: This study indicates fluorescence visualization is capable of improve inexperienced professionals' efficacy for early detecting oral lesions more prone to be dysplastic and oral potentially malignant disorders. (C) 2016 Elsevier B.V. All rights reserved.Camilo Castelo Branco Univ UNICASTELO, Biomed Engn Inst, Sao Jose Dos Campos, SP, BrazilUniv Estadual Paulista, UNESP, Aracatuba Dent Sch, Oral Oncol Ctr, Aracatuba, BrazilUniv Estadual Paulista, UNESP, Aracatuba Dent Sch, Oral Oncol Ctr, Aracatuba, BrazilElsevier B.V.Camilo Castelo Branco Univ UNICASTELOUniversidade Estadual Paulista (Unesp)Simonato, Luciana EstevamTomo, Saygo [UNESP]Miyahara, Glauco Issamu [UNESP]Navarro, Ricardo ScarparoJose Balbin Villaverde, Antonio Guillermo2018-11-26T17:28:18Z2018-11-26T17:28:18Z2017-03-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1-4application/pdfhttp://dx.doi.org/10.1016/j.pdpdt.2016.10.010Photodiagnosis And Photodynamic Therapy. Amsterdam: Elsevier Science Bv, v. 17, p. 1-4, 2017.1572-1000http://hdl.handle.net/11449/16271810.1016/j.pdpdt.2016.10.010WOS:000399507000004WOS000399507000004.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengPhotodiagnosis And Photodynamic Therapy0,647info:eu-repo/semantics/openAccess2024-04-11T20:16:33Zoai:repositorio.unesp.br:11449/162718Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T17:17:16.545872Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Fluorescence visualization efficacy for detecting oral lesions more prone to be dysplastic and potentially malignant disorders: a pilot study |
title |
Fluorescence visualization efficacy for detecting oral lesions more prone to be dysplastic and potentially malignant disorders: a pilot study |
spellingShingle |
Fluorescence visualization efficacy for detecting oral lesions more prone to be dysplastic and potentially malignant disorders: a pilot study Simonato, Luciana Estevam Optical imaging Diagnosis Oral Early diagnosis Mouth neoplasms |
title_short |
Fluorescence visualization efficacy for detecting oral lesions more prone to be dysplastic and potentially malignant disorders: a pilot study |
title_full |
Fluorescence visualization efficacy for detecting oral lesions more prone to be dysplastic and potentially malignant disorders: a pilot study |
title_fullStr |
Fluorescence visualization efficacy for detecting oral lesions more prone to be dysplastic and potentially malignant disorders: a pilot study |
title_full_unstemmed |
Fluorescence visualization efficacy for detecting oral lesions more prone to be dysplastic and potentially malignant disorders: a pilot study |
title_sort |
Fluorescence visualization efficacy for detecting oral lesions more prone to be dysplastic and potentially malignant disorders: a pilot study |
author |
Simonato, Luciana Estevam |
author_facet |
Simonato, Luciana Estevam Tomo, Saygo [UNESP] Miyahara, Glauco Issamu [UNESP] Navarro, Ricardo Scarparo Jose Balbin Villaverde, Antonio Guillermo |
author_role |
author |
author2 |
Tomo, Saygo [UNESP] Miyahara, Glauco Issamu [UNESP] Navarro, Ricardo Scarparo Jose Balbin Villaverde, Antonio Guillermo |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Camilo Castelo Branco Univ UNICASTELO Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Simonato, Luciana Estevam Tomo, Saygo [UNESP] Miyahara, Glauco Issamu [UNESP] Navarro, Ricardo Scarparo Jose Balbin Villaverde, Antonio Guillermo |
dc.subject.por.fl_str_mv |
Optical imaging Diagnosis Oral Early diagnosis Mouth neoplasms |
topic |
Optical imaging Diagnosis Oral Early diagnosis Mouth neoplasms |
description |
Background: To analyze the efficacy of fluorescence visualization in early detection of oral early neoplastic processes when used by an inexperienced and an adept oral examiner. Methods: A dental student and an expert professional in oral diagnosis examined 15 randomly selected patients using conventional oral examination and fluorescence visualization searching for early signs of epithelial dysplasia and oral potentially malignant disorders. Patients detected with oral lesions in any of examinations were submitted to incisional biopsy for definitive diagnosis. Results: Taking histopathologic analysis as Gold Standard, sensitivity, specificity, positive and negative predictive values and accuracy of inexperienced examiner for detecting both epithelium dysplasia and oral potentially malignant disorders increased when using fluorescence visualization compared to conventional white light examination, matching the same values found for expert professional in oral diagnosis. Furthermore, it was possible to observe discrete increase in the efficacy of expert professional's examination when using fluorescence visualization. Conclusion: This study indicates fluorescence visualization is capable of improve inexperienced professionals' efficacy for early detecting oral lesions more prone to be dysplastic and oral potentially malignant disorders. (C) 2016 Elsevier B.V. All rights reserved. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-03-01 2018-11-26T17:28:18Z 2018-11-26T17:28:18Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.pdpdt.2016.10.010 Photodiagnosis And Photodynamic Therapy. Amsterdam: Elsevier Science Bv, v. 17, p. 1-4, 2017. 1572-1000 http://hdl.handle.net/11449/162718 10.1016/j.pdpdt.2016.10.010 WOS:000399507000004 WOS000399507000004.pdf |
url |
http://dx.doi.org/10.1016/j.pdpdt.2016.10.010 http://hdl.handle.net/11449/162718 |
identifier_str_mv |
Photodiagnosis And Photodynamic Therapy. Amsterdam: Elsevier Science Bv, v. 17, p. 1-4, 2017. 1572-1000 10.1016/j.pdpdt.2016.10.010 WOS:000399507000004 WOS000399507000004.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Photodiagnosis And Photodynamic Therapy 0,647 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
1-4 application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier B.V. |
publisher.none.fl_str_mv |
Elsevier B.V. |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128785081434112 |