Phenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae)

Detalhes bibliográficos
Autor(a) principal: Lima Cardoso, Claudia Andrea
Data de Publicação: 2013
Outros Autores: Coelho, Roberta Gomes, Honda, Neli Kika, Pott, Arnildo, Pavan, Fernando Rogério [UNESP], Leite, Clarice Queico Fujimura [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/S1984-82502013000400017
http://hdl.handle.net/11449/113444
Resumo: Serjania erecta Radlk.(Sapindaceae) is a medicinal plant traditionally used in Brazil. We assayed the ethanolic extract of leaves and roots against seven microorganisms. The REMA (Resazurin Microtiter Assay) assay was used to measure the biological activity in vitro against Mycobacterium tuberculosis and our results showed moderate activity of the ethanolic extract. On the other hand S. aureus, P. aeruginosa, S. setubal, C. albicans, S. cerevisiae and E. coli revealed that the leaves and roots of S. erecta inhibited the growth of all microorganisms. The ethanolic extracts of leaves and roots showed low values of antioxidant activities. The ethanolic extracts of leaves and roots were analyzed by chromatographic and spectrometric methods. (-)-Epicatechin, kaempferol aglycone and five glycoside derivates were isolated: kaempferol-3-O-alpha-L-rhamnopyranoside, kaempferol-3-O-alpha-L-rhamnopyranosyl-(1 -> 6)-beta-D-glucopyranoside from the roots and kaempferol, kaempferol 3,7-di-O-alpha-L-rhamnopyranoside, vitexin, isovitexin and (-)-epicatechin in the leaves. This is the first chemical study reported in the literature about this specie.
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spelling Phenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae)Serjania erecta Radlk/pharmacognosySerjania erecta Radlk/ethanolic extract/antioxidant activitySerjania erecta Radlk/ethanolic extract/antimicrobial activitySapindaceae/pharmacognosyCipo-cinco-folhas/pharmacognosyFlavonoidsMedicinal plantsSerjania erecta Radlk.(Sapindaceae) is a medicinal plant traditionally used in Brazil. We assayed the ethanolic extract of leaves and roots against seven microorganisms. The REMA (Resazurin Microtiter Assay) assay was used to measure the biological activity in vitro against Mycobacterium tuberculosis and our results showed moderate activity of the ethanolic extract. On the other hand S. aureus, P. aeruginosa, S. setubal, C. albicans, S. cerevisiae and E. coli revealed that the leaves and roots of S. erecta inhibited the growth of all microorganisms. The ethanolic extracts of leaves and roots showed low values of antioxidant activities. The ethanolic extracts of leaves and roots were analyzed by chromatographic and spectrometric methods. (-)-Epicatechin, kaempferol aglycone and five glycoside derivates were isolated: kaempferol-3-O-alpha-L-rhamnopyranoside, kaempferol-3-O-alpha-L-rhamnopyranosyl-(1 -> 6)-beta-D-glucopyranoside from the roots and kaempferol, kaempferol 3,7-di-O-alpha-L-rhamnopyranoside, vitexin, isovitexin and (-)-epicatechin in the leaves. This is the first chemical study reported in the literature about this specie.Fundacao de Apoio ao Desenvolvimento do Ensino, Ciencia e Tecnologia do Estado de Mato Grosso do Sul (FUNDECT)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Univ Estadual Mato Grosso do Sul, Course Chem, Dourados, MS, BrazilUniv Fed Mato Grosso do Sul, Inst Chem, Campo Grande, MS, BrazilUniv Fed Mato Grosso do Sul, Dept Biol, Campo Grande, MS, BrazilUniv Estadual Paulista, Fac Pharmaceut Sci, Dept Biol Sci, Araraquara, SP, BrazilUniv Estadual Paulista, Fac Pharmaceut Sci, Dept Biol Sci, Araraquara, SP, BrazilUniversidade de São Paulo (USP), Conjunto QuimicasUniversidade Estadual de Mato Grosso do Sul (UEMS)Universidade Federal de Mato Grosso do Sul (UFMS)Universidade Estadual Paulista (Unesp)Lima Cardoso, Claudia AndreaCoelho, Roberta GomesHonda, Neli KikaPott, ArnildoPavan, Fernando Rogério [UNESP]Leite, Clarice Queico Fujimura [UNESP]2014-12-03T13:11:42Z2014-12-03T13:11:42Z2013-10-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article775-782application/pdfhttp://dx.doi.org/10.1590/S1984-82502013000400017Brazilian Journal of Pharmaceutical Sciences. São Paulo: Univ São Paulo, Conjunto Quimicas, v. 49, n. 4, p. 775-782, 2013.1984-8250http://hdl.handle.net/11449/113444S1984-82502013000400017WOS:000333047500017S1984-82502013000400017.pdf2114570774349859Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBrazilian Journal of Pharmaceutical Sciences0.4830,214info:eu-repo/semantics/openAccess2024-06-24T13:08:25Zoai:repositorio.unesp.br:11449/113444Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T22:39:11.556053Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Phenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae)
title Phenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae)
spellingShingle Phenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae)
Lima Cardoso, Claudia Andrea
Serjania erecta Radlk/pharmacognosy
Serjania erecta Radlk/ethanolic extract/antioxidant activity
Serjania erecta Radlk/ethanolic extract/antimicrobial activity
Sapindaceae/pharmacognosy
Cipo-cinco-folhas/pharmacognosy
Flavonoids
Medicinal plants
title_short Phenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae)
title_full Phenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae)
title_fullStr Phenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae)
title_full_unstemmed Phenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae)
title_sort Phenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae)
author Lima Cardoso, Claudia Andrea
author_facet Lima Cardoso, Claudia Andrea
Coelho, Roberta Gomes
Honda, Neli Kika
Pott, Arnildo
Pavan, Fernando Rogério [UNESP]
Leite, Clarice Queico Fujimura [UNESP]
author_role author
author2 Coelho, Roberta Gomes
Honda, Neli Kika
Pott, Arnildo
Pavan, Fernando Rogério [UNESP]
Leite, Clarice Queico Fujimura [UNESP]
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual de Mato Grosso do Sul (UEMS)
Universidade Federal de Mato Grosso do Sul (UFMS)
Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Lima Cardoso, Claudia Andrea
Coelho, Roberta Gomes
Honda, Neli Kika
Pott, Arnildo
Pavan, Fernando Rogério [UNESP]
Leite, Clarice Queico Fujimura [UNESP]
dc.subject.por.fl_str_mv Serjania erecta Radlk/pharmacognosy
Serjania erecta Radlk/ethanolic extract/antioxidant activity
Serjania erecta Radlk/ethanolic extract/antimicrobial activity
Sapindaceae/pharmacognosy
Cipo-cinco-folhas/pharmacognosy
Flavonoids
Medicinal plants
topic Serjania erecta Radlk/pharmacognosy
Serjania erecta Radlk/ethanolic extract/antioxidant activity
Serjania erecta Radlk/ethanolic extract/antimicrobial activity
Sapindaceae/pharmacognosy
Cipo-cinco-folhas/pharmacognosy
Flavonoids
Medicinal plants
description Serjania erecta Radlk.(Sapindaceae) is a medicinal plant traditionally used in Brazil. We assayed the ethanolic extract of leaves and roots against seven microorganisms. The REMA (Resazurin Microtiter Assay) assay was used to measure the biological activity in vitro against Mycobacterium tuberculosis and our results showed moderate activity of the ethanolic extract. On the other hand S. aureus, P. aeruginosa, S. setubal, C. albicans, S. cerevisiae and E. coli revealed that the leaves and roots of S. erecta inhibited the growth of all microorganisms. The ethanolic extracts of leaves and roots showed low values of antioxidant activities. The ethanolic extracts of leaves and roots were analyzed by chromatographic and spectrometric methods. (-)-Epicatechin, kaempferol aglycone and five glycoside derivates were isolated: kaempferol-3-O-alpha-L-rhamnopyranoside, kaempferol-3-O-alpha-L-rhamnopyranosyl-(1 -> 6)-beta-D-glucopyranoside from the roots and kaempferol, kaempferol 3,7-di-O-alpha-L-rhamnopyranoside, vitexin, isovitexin and (-)-epicatechin in the leaves. This is the first chemical study reported in the literature about this specie.
publishDate 2013
dc.date.none.fl_str_mv 2013-10-01
2014-12-03T13:11:42Z
2014-12-03T13:11:42Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S1984-82502013000400017
Brazilian Journal of Pharmaceutical Sciences. São Paulo: Univ São Paulo, Conjunto Quimicas, v. 49, n. 4, p. 775-782, 2013.
1984-8250
http://hdl.handle.net/11449/113444
S1984-82502013000400017
WOS:000333047500017
S1984-82502013000400017.pdf
2114570774349859
url http://dx.doi.org/10.1590/S1984-82502013000400017
http://hdl.handle.net/11449/113444
identifier_str_mv Brazilian Journal of Pharmaceutical Sciences. São Paulo: Univ São Paulo, Conjunto Quimicas, v. 49, n. 4, p. 775-782, 2013.
1984-8250
S1984-82502013000400017
WOS:000333047500017
S1984-82502013000400017.pdf
2114570774349859
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Brazilian Journal of Pharmaceutical Sciences
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0,214
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 775-782
application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo (USP), Conjunto Quimicas
publisher.none.fl_str_mv Universidade de São Paulo (USP), Conjunto Quimicas
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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