Phenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae)
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/S1984-82502013000400017 http://hdl.handle.net/11449/113444 |
Resumo: | Serjania erecta Radlk.(Sapindaceae) is a medicinal plant traditionally used in Brazil. We assayed the ethanolic extract of leaves and roots against seven microorganisms. The REMA (Resazurin Microtiter Assay) assay was used to measure the biological activity in vitro against Mycobacterium tuberculosis and our results showed moderate activity of the ethanolic extract. On the other hand S. aureus, P. aeruginosa, S. setubal, C. albicans, S. cerevisiae and E. coli revealed that the leaves and roots of S. erecta inhibited the growth of all microorganisms. The ethanolic extracts of leaves and roots showed low values of antioxidant activities. The ethanolic extracts of leaves and roots were analyzed by chromatographic and spectrometric methods. (-)-Epicatechin, kaempferol aglycone and five glycoside derivates were isolated: kaempferol-3-O-alpha-L-rhamnopyranoside, kaempferol-3-O-alpha-L-rhamnopyranosyl-(1 -> 6)-beta-D-glucopyranoside from the roots and kaempferol, kaempferol 3,7-di-O-alpha-L-rhamnopyranoside, vitexin, isovitexin and (-)-epicatechin in the leaves. This is the first chemical study reported in the literature about this specie. |
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Phenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae)Serjania erecta Radlk/pharmacognosySerjania erecta Radlk/ethanolic extract/antioxidant activitySerjania erecta Radlk/ethanolic extract/antimicrobial activitySapindaceae/pharmacognosyCipo-cinco-folhas/pharmacognosyFlavonoidsMedicinal plantsSerjania erecta Radlk.(Sapindaceae) is a medicinal plant traditionally used in Brazil. We assayed the ethanolic extract of leaves and roots against seven microorganisms. The REMA (Resazurin Microtiter Assay) assay was used to measure the biological activity in vitro against Mycobacterium tuberculosis and our results showed moderate activity of the ethanolic extract. On the other hand S. aureus, P. aeruginosa, S. setubal, C. albicans, S. cerevisiae and E. coli revealed that the leaves and roots of S. erecta inhibited the growth of all microorganisms. The ethanolic extracts of leaves and roots showed low values of antioxidant activities. The ethanolic extracts of leaves and roots were analyzed by chromatographic and spectrometric methods. (-)-Epicatechin, kaempferol aglycone and five glycoside derivates were isolated: kaempferol-3-O-alpha-L-rhamnopyranoside, kaempferol-3-O-alpha-L-rhamnopyranosyl-(1 -> 6)-beta-D-glucopyranoside from the roots and kaempferol, kaempferol 3,7-di-O-alpha-L-rhamnopyranoside, vitexin, isovitexin and (-)-epicatechin in the leaves. This is the first chemical study reported in the literature about this specie.Fundacao de Apoio ao Desenvolvimento do Ensino, Ciencia e Tecnologia do Estado de Mato Grosso do Sul (FUNDECT)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Univ Estadual Mato Grosso do Sul, Course Chem, Dourados, MS, BrazilUniv Fed Mato Grosso do Sul, Inst Chem, Campo Grande, MS, BrazilUniv Fed Mato Grosso do Sul, Dept Biol, Campo Grande, MS, BrazilUniv Estadual Paulista, Fac Pharmaceut Sci, Dept Biol Sci, Araraquara, SP, BrazilUniv Estadual Paulista, Fac Pharmaceut Sci, Dept Biol Sci, Araraquara, SP, BrazilUniversidade de São Paulo (USP), Conjunto QuimicasUniversidade Estadual de Mato Grosso do Sul (UEMS)Universidade Federal de Mato Grosso do Sul (UFMS)Universidade Estadual Paulista (Unesp)Lima Cardoso, Claudia AndreaCoelho, Roberta GomesHonda, Neli KikaPott, ArnildoPavan, Fernando Rogério [UNESP]Leite, Clarice Queico Fujimura [UNESP]2014-12-03T13:11:42Z2014-12-03T13:11:42Z2013-10-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article775-782application/pdfhttp://dx.doi.org/10.1590/S1984-82502013000400017Brazilian Journal of Pharmaceutical Sciences. São Paulo: Univ São Paulo, Conjunto Quimicas, v. 49, n. 4, p. 775-782, 2013.1984-8250http://hdl.handle.net/11449/113444S1984-82502013000400017WOS:000333047500017S1984-82502013000400017.pdf2114570774349859Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBrazilian Journal of Pharmaceutical Sciences0.4830,214info:eu-repo/semantics/openAccess2024-06-24T13:08:25Zoai:repositorio.unesp.br:11449/113444Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T22:39:11.556053Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Phenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae) |
title |
Phenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae) |
spellingShingle |
Phenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae) Lima Cardoso, Claudia Andrea Serjania erecta Radlk/pharmacognosy Serjania erecta Radlk/ethanolic extract/antioxidant activity Serjania erecta Radlk/ethanolic extract/antimicrobial activity Sapindaceae/pharmacognosy Cipo-cinco-folhas/pharmacognosy Flavonoids Medicinal plants |
title_short |
Phenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae) |
title_full |
Phenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae) |
title_fullStr |
Phenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae) |
title_full_unstemmed |
Phenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae) |
title_sort |
Phenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae) |
author |
Lima Cardoso, Claudia Andrea |
author_facet |
Lima Cardoso, Claudia Andrea Coelho, Roberta Gomes Honda, Neli Kika Pott, Arnildo Pavan, Fernando Rogério [UNESP] Leite, Clarice Queico Fujimura [UNESP] |
author_role |
author |
author2 |
Coelho, Roberta Gomes Honda, Neli Kika Pott, Arnildo Pavan, Fernando Rogério [UNESP] Leite, Clarice Queico Fujimura [UNESP] |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual de Mato Grosso do Sul (UEMS) Universidade Federal de Mato Grosso do Sul (UFMS) Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Lima Cardoso, Claudia Andrea Coelho, Roberta Gomes Honda, Neli Kika Pott, Arnildo Pavan, Fernando Rogério [UNESP] Leite, Clarice Queico Fujimura [UNESP] |
dc.subject.por.fl_str_mv |
Serjania erecta Radlk/pharmacognosy Serjania erecta Radlk/ethanolic extract/antioxidant activity Serjania erecta Radlk/ethanolic extract/antimicrobial activity Sapindaceae/pharmacognosy Cipo-cinco-folhas/pharmacognosy Flavonoids Medicinal plants |
topic |
Serjania erecta Radlk/pharmacognosy Serjania erecta Radlk/ethanolic extract/antioxidant activity Serjania erecta Radlk/ethanolic extract/antimicrobial activity Sapindaceae/pharmacognosy Cipo-cinco-folhas/pharmacognosy Flavonoids Medicinal plants |
description |
Serjania erecta Radlk.(Sapindaceae) is a medicinal plant traditionally used in Brazil. We assayed the ethanolic extract of leaves and roots against seven microorganisms. The REMA (Resazurin Microtiter Assay) assay was used to measure the biological activity in vitro against Mycobacterium tuberculosis and our results showed moderate activity of the ethanolic extract. On the other hand S. aureus, P. aeruginosa, S. setubal, C. albicans, S. cerevisiae and E. coli revealed that the leaves and roots of S. erecta inhibited the growth of all microorganisms. The ethanolic extracts of leaves and roots showed low values of antioxidant activities. The ethanolic extracts of leaves and roots were analyzed by chromatographic and spectrometric methods. (-)-Epicatechin, kaempferol aglycone and five glycoside derivates were isolated: kaempferol-3-O-alpha-L-rhamnopyranoside, kaempferol-3-O-alpha-L-rhamnopyranosyl-(1 -> 6)-beta-D-glucopyranoside from the roots and kaempferol, kaempferol 3,7-di-O-alpha-L-rhamnopyranoside, vitexin, isovitexin and (-)-epicatechin in the leaves. This is the first chemical study reported in the literature about this specie. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-10-01 2014-12-03T13:11:42Z 2014-12-03T13:11:42Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S1984-82502013000400017 Brazilian Journal of Pharmaceutical Sciences. São Paulo: Univ São Paulo, Conjunto Quimicas, v. 49, n. 4, p. 775-782, 2013. 1984-8250 http://hdl.handle.net/11449/113444 S1984-82502013000400017 WOS:000333047500017 S1984-82502013000400017.pdf 2114570774349859 |
url |
http://dx.doi.org/10.1590/S1984-82502013000400017 http://hdl.handle.net/11449/113444 |
identifier_str_mv |
Brazilian Journal of Pharmaceutical Sciences. São Paulo: Univ São Paulo, Conjunto Quimicas, v. 49, n. 4, p. 775-782, 2013. 1984-8250 S1984-82502013000400017 WOS:000333047500017 S1984-82502013000400017.pdf 2114570774349859 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Brazilian Journal of Pharmaceutical Sciences 0.483 0,214 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
775-782 application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo (USP), Conjunto Quimicas |
publisher.none.fl_str_mv |
Universidade de São Paulo (USP), Conjunto Quimicas |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129446826213376 |