Relationship between disease severity and quality of life in patients with chronic obstructive pulmonary disease
Autor(a) principal: | |
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Data de Publicação: | 2008 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/S0100-879X2008005000043 http://hdl.handle.net/11449/17054 |
Resumo: | Few studies have evaluated the relationship between Airways Questionnaire 20 (AQ20), a measure of the quality of life, scores and physiological outcomes or with systemic markers of disease in patients with chronic obstructive pulmonary disease (COPD). The aim of the present study was to investigate the relationship of forced expiratory volume in 1 s (FEV1), body mass index, fat-free mass index, 6-min walk test (6MWT) results, dyspnea sensation and peripheral oxygen saturation (SpO2) with the quality of life of COPD patients. Ninety-nine patients with COPD (mean age: 64.2 ± 9.2 years; mean FEV1: 60.4 ± 25.2% of predicted) were evaluated using spirometry, body composition measurement and the 6MWT. The baseline dyspnea index (BDI) and the Modified Medical Research Council (MMRC) scale were used to quantify dyspnea. Quality of life was assessed using the AQ20 and the St. George's Respiratory Questionnaire (SGRQ). The Charlson index was used to determine comorbidity. The body mass index/airflow obstruction/dyspnea/exercise capacity (BODE) index was also calculated. AQ20 and SGRQ scores correlated significantly with FEV1, SpO2, 6MWT, MMRC and BDI values as did with BODE index. In the multivariate analyses, MMRC or BDI were identified as predictors of AQ20 and SGRQ scores (P < 0.001 in all cases). Thus, the relationship between AQ20 and disease severity is similar to that described for SGRQ. Therefore, the AQ20, a simple and brief instrument, can be very useful to evaluate the general impact of disease when the time allotted for measurement of the quality of life is limited. |
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Relationship between disease severity and quality of life in patients with chronic obstructive pulmonary diseasePulmonary diseaseChronic obstructive pulmonary diseaseSt. George's Respiratory QuestionnaireAirways Questionnaire 20Respiratory systemFew studies have evaluated the relationship between Airways Questionnaire 20 (AQ20), a measure of the quality of life, scores and physiological outcomes or with systemic markers of disease in patients with chronic obstructive pulmonary disease (COPD). The aim of the present study was to investigate the relationship of forced expiratory volume in 1 s (FEV1), body mass index, fat-free mass index, 6-min walk test (6MWT) results, dyspnea sensation and peripheral oxygen saturation (SpO2) with the quality of life of COPD patients. Ninety-nine patients with COPD (mean age: 64.2 ± 9.2 years; mean FEV1: 60.4 ± 25.2% of predicted) were evaluated using spirometry, body composition measurement and the 6MWT. The baseline dyspnea index (BDI) and the Modified Medical Research Council (MMRC) scale were used to quantify dyspnea. Quality of life was assessed using the AQ20 and the St. George's Respiratory Questionnaire (SGRQ). The Charlson index was used to determine comorbidity. The body mass index/airflow obstruction/dyspnea/exercise capacity (BODE) index was also calculated. AQ20 and SGRQ scores correlated significantly with FEV1, SpO2, 6MWT, MMRC and BDI values as did with BODE index. In the multivariate analyses, MMRC or BDI were identified as predictors of AQ20 and SGRQ scores (P < 0.001 in all cases). Thus, the relationship between AQ20 and disease severity is similar to that described for SGRQ. Therefore, the AQ20, a simple and brief instrument, can be very useful to evaluate the general impact of disease when the time allotted for measurement of the quality of life is limited.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Centro Universitário Católico Salesiano Auxilium (Unisalesiano) Departamento de FisioterapiaFaculdades Adamantinenses IntegradasUnisalesiano de Lins Departamento de FisioterapiaUniversidade Estadual Paulista Faculdade de Medicina de Botucatu Departamento de Medicina InternaUniversidade Estadual Paulista Instistuto de Biociências Departamento de BioestatísticaUniversidade Estadual Paulista Faculdade de Medicina de Botucatu Departamento de Medicina InternaUniversidade Estadual Paulista Instistuto de Biociências Departamento de BioestatísticaFAPESP: 04/00517-4Associação Brasileira de Divulgação Científica (ABRADIC)Centro Universitário Católico Salesiano Auxilium (UNISALESIANO)Faculdades Adamantinenses Integradas (FAI)Universidade Estadual Paulista (Unesp)Sanchez, F. F.Faganello, M. M.Tanni, S. E. [UNESP]Lucheta, P. A. [UNESP]Padovani, C. R. [UNESP]Godoy, I. [UNESP]2014-05-20T13:47:51Z2014-05-20T13:47:51Z2008-10-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article860-865application/pdfhttp://dx.doi.org/10.1590/S0100-879X2008005000043Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 41, n. 10, p. 860-865, 2008.0100-879Xhttp://hdl.handle.net/11449/1705410.1590/S0100-879X2008005000043S0100-879X2008001000005WOS:000261171400005S0100-879X2008001000005.pdf8727897080522289SciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBrazilian Journal of Medical and Biological Research1.492info:eu-repo/semantics/openAccess2023-12-30T06:22:07Zoai:repositorio.unesp.br:11449/17054Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T21:43:31.212005Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Relationship between disease severity and quality of life in patients with chronic obstructive pulmonary disease |
title |
Relationship between disease severity and quality of life in patients with chronic obstructive pulmonary disease |
spellingShingle |
Relationship between disease severity and quality of life in patients with chronic obstructive pulmonary disease Sanchez, F. F. Pulmonary disease Chronic obstructive pulmonary disease St. George's Respiratory Questionnaire Airways Questionnaire 20 Respiratory system |
title_short |
Relationship between disease severity and quality of life in patients with chronic obstructive pulmonary disease |
title_full |
Relationship between disease severity and quality of life in patients with chronic obstructive pulmonary disease |
title_fullStr |
Relationship between disease severity and quality of life in patients with chronic obstructive pulmonary disease |
title_full_unstemmed |
Relationship between disease severity and quality of life in patients with chronic obstructive pulmonary disease |
title_sort |
Relationship between disease severity and quality of life in patients with chronic obstructive pulmonary disease |
author |
Sanchez, F. F. |
author_facet |
Sanchez, F. F. Faganello, M. M. Tanni, S. E. [UNESP] Lucheta, P. A. [UNESP] Padovani, C. R. [UNESP] Godoy, I. [UNESP] |
author_role |
author |
author2 |
Faganello, M. M. Tanni, S. E. [UNESP] Lucheta, P. A. [UNESP] Padovani, C. R. [UNESP] Godoy, I. [UNESP] |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Centro Universitário Católico Salesiano Auxilium (UNISALESIANO) Faculdades Adamantinenses Integradas (FAI) Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Sanchez, F. F. Faganello, M. M. Tanni, S. E. [UNESP] Lucheta, P. A. [UNESP] Padovani, C. R. [UNESP] Godoy, I. [UNESP] |
dc.subject.por.fl_str_mv |
Pulmonary disease Chronic obstructive pulmonary disease St. George's Respiratory Questionnaire Airways Questionnaire 20 Respiratory system |
topic |
Pulmonary disease Chronic obstructive pulmonary disease St. George's Respiratory Questionnaire Airways Questionnaire 20 Respiratory system |
description |
Few studies have evaluated the relationship between Airways Questionnaire 20 (AQ20), a measure of the quality of life, scores and physiological outcomes or with systemic markers of disease in patients with chronic obstructive pulmonary disease (COPD). The aim of the present study was to investigate the relationship of forced expiratory volume in 1 s (FEV1), body mass index, fat-free mass index, 6-min walk test (6MWT) results, dyspnea sensation and peripheral oxygen saturation (SpO2) with the quality of life of COPD patients. Ninety-nine patients with COPD (mean age: 64.2 ± 9.2 years; mean FEV1: 60.4 ± 25.2% of predicted) were evaluated using spirometry, body composition measurement and the 6MWT. The baseline dyspnea index (BDI) and the Modified Medical Research Council (MMRC) scale were used to quantify dyspnea. Quality of life was assessed using the AQ20 and the St. George's Respiratory Questionnaire (SGRQ). The Charlson index was used to determine comorbidity. The body mass index/airflow obstruction/dyspnea/exercise capacity (BODE) index was also calculated. AQ20 and SGRQ scores correlated significantly with FEV1, SpO2, 6MWT, MMRC and BDI values as did with BODE index. In the multivariate analyses, MMRC or BDI were identified as predictors of AQ20 and SGRQ scores (P < 0.001 in all cases). Thus, the relationship between AQ20 and disease severity is similar to that described for SGRQ. Therefore, the AQ20, a simple and brief instrument, can be very useful to evaluate the general impact of disease when the time allotted for measurement of the quality of life is limited. |
publishDate |
2008 |
dc.date.none.fl_str_mv |
2008-10-01 2014-05-20T13:47:51Z 2014-05-20T13:47:51Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S0100-879X2008005000043 Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 41, n. 10, p. 860-865, 2008. 0100-879X http://hdl.handle.net/11449/17054 10.1590/S0100-879X2008005000043 S0100-879X2008001000005 WOS:000261171400005 S0100-879X2008001000005.pdf 8727897080522289 |
url |
http://dx.doi.org/10.1590/S0100-879X2008005000043 http://hdl.handle.net/11449/17054 |
identifier_str_mv |
Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 41, n. 10, p. 860-865, 2008. 0100-879X 10.1590/S0100-879X2008005000043 S0100-879X2008001000005 WOS:000261171400005 S0100-879X2008001000005.pdf 8727897080522289 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Brazilian Journal of Medical and Biological Research 1.492 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
860-865 application/pdf |
dc.publisher.none.fl_str_mv |
Associação Brasileira de Divulgação Científica (ABRADIC) |
publisher.none.fl_str_mv |
Associação Brasileira de Divulgação Científica (ABRADIC) |
dc.source.none.fl_str_mv |
SciELO reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
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1808129350716882944 |