Relationship between disease severity and quality of life in patients with chronic obstructive pulmonary disease

Detalhes bibliográficos
Autor(a) principal: Sanchez, F. F.
Data de Publicação: 2008
Outros Autores: Faganello, M. M., Tanni, S. E. [UNESP], Lucheta, P. A. [UNESP], Padovani, C. R. [UNESP], Godoy, I. [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/S0100-879X2008005000043
http://hdl.handle.net/11449/17054
Resumo: Few studies have evaluated the relationship between Airways Questionnaire 20 (AQ20), a measure of the quality of life, scores and physiological outcomes or with systemic markers of disease in patients with chronic obstructive pulmonary disease (COPD). The aim of the present study was to investigate the relationship of forced expiratory volume in 1 s (FEV1), body mass index, fat-free mass index, 6-min walk test (6MWT) results, dyspnea sensation and peripheral oxygen saturation (SpO2) with the quality of life of COPD patients. Ninety-nine patients with COPD (mean age: 64.2 ± 9.2 years; mean FEV1: 60.4 ± 25.2% of predicted) were evaluated using spirometry, body composition measurement and the 6MWT. The baseline dyspnea index (BDI) and the Modified Medical Research Council (MMRC) scale were used to quantify dyspnea. Quality of life was assessed using the AQ20 and the St. George's Respiratory Questionnaire (SGRQ). The Charlson index was used to determine comorbidity. The body mass index/airflow obstruction/dyspnea/exercise capacity (BODE) index was also calculated. AQ20 and SGRQ scores correlated significantly with FEV1, SpO2, 6MWT, MMRC and BDI values as did with BODE index. In the multivariate analyses, MMRC or BDI were identified as predictors of AQ20 and SGRQ scores (P < 0.001 in all cases). Thus, the relationship between AQ20 and disease severity is similar to that described for SGRQ. Therefore, the AQ20, a simple and brief instrument, can be very useful to evaluate the general impact of disease when the time allotted for measurement of the quality of life is limited.
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spelling Relationship between disease severity and quality of life in patients with chronic obstructive pulmonary diseasePulmonary diseaseChronic obstructive pulmonary diseaseSt. George's Respiratory QuestionnaireAirways Questionnaire 20Respiratory systemFew studies have evaluated the relationship between Airways Questionnaire 20 (AQ20), a measure of the quality of life, scores and physiological outcomes or with systemic markers of disease in patients with chronic obstructive pulmonary disease (COPD). The aim of the present study was to investigate the relationship of forced expiratory volume in 1 s (FEV1), body mass index, fat-free mass index, 6-min walk test (6MWT) results, dyspnea sensation and peripheral oxygen saturation (SpO2) with the quality of life of COPD patients. Ninety-nine patients with COPD (mean age: 64.2 ± 9.2 years; mean FEV1: 60.4 ± 25.2% of predicted) were evaluated using spirometry, body composition measurement and the 6MWT. The baseline dyspnea index (BDI) and the Modified Medical Research Council (MMRC) scale were used to quantify dyspnea. Quality of life was assessed using the AQ20 and the St. George's Respiratory Questionnaire (SGRQ). The Charlson index was used to determine comorbidity. The body mass index/airflow obstruction/dyspnea/exercise capacity (BODE) index was also calculated. AQ20 and SGRQ scores correlated significantly with FEV1, SpO2, 6MWT, MMRC and BDI values as did with BODE index. In the multivariate analyses, MMRC or BDI were identified as predictors of AQ20 and SGRQ scores (P < 0.001 in all cases). Thus, the relationship between AQ20 and disease severity is similar to that described for SGRQ. Therefore, the AQ20, a simple and brief instrument, can be very useful to evaluate the general impact of disease when the time allotted for measurement of the quality of life is limited.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Centro Universitário Católico Salesiano Auxilium (Unisalesiano) Departamento de FisioterapiaFaculdades Adamantinenses IntegradasUnisalesiano de Lins Departamento de FisioterapiaUniversidade Estadual Paulista Faculdade de Medicina de Botucatu Departamento de Medicina InternaUniversidade Estadual Paulista Instistuto de Biociências Departamento de BioestatísticaUniversidade Estadual Paulista Faculdade de Medicina de Botucatu Departamento de Medicina InternaUniversidade Estadual Paulista Instistuto de Biociências Departamento de BioestatísticaFAPESP: 04/00517-4Associação Brasileira de Divulgação Científica (ABRADIC)Centro Universitário Católico Salesiano Auxilium (UNISALESIANO)Faculdades Adamantinenses Integradas (FAI)Universidade Estadual Paulista (Unesp)Sanchez, F. F.Faganello, M. M.Tanni, S. E. [UNESP]Lucheta, P. A. [UNESP]Padovani, C. R. [UNESP]Godoy, I. [UNESP]2014-05-20T13:47:51Z2014-05-20T13:47:51Z2008-10-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article860-865application/pdfhttp://dx.doi.org/10.1590/S0100-879X2008005000043Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 41, n. 10, p. 860-865, 2008.0100-879Xhttp://hdl.handle.net/11449/1705410.1590/S0100-879X2008005000043S0100-879X2008001000005WOS:000261171400005S0100-879X2008001000005.pdf8727897080522289SciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBrazilian Journal of Medical and Biological Research1.492info:eu-repo/semantics/openAccess2023-12-30T06:22:07Zoai:repositorio.unesp.br:11449/17054Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T21:43:31.212005Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Relationship between disease severity and quality of life in patients with chronic obstructive pulmonary disease
title Relationship between disease severity and quality of life in patients with chronic obstructive pulmonary disease
spellingShingle Relationship between disease severity and quality of life in patients with chronic obstructive pulmonary disease
Sanchez, F. F.
Pulmonary disease
Chronic obstructive pulmonary disease
St. George's Respiratory Questionnaire
Airways Questionnaire 20
Respiratory system
title_short Relationship between disease severity and quality of life in patients with chronic obstructive pulmonary disease
title_full Relationship between disease severity and quality of life in patients with chronic obstructive pulmonary disease
title_fullStr Relationship between disease severity and quality of life in patients with chronic obstructive pulmonary disease
title_full_unstemmed Relationship between disease severity and quality of life in patients with chronic obstructive pulmonary disease
title_sort Relationship between disease severity and quality of life in patients with chronic obstructive pulmonary disease
author Sanchez, F. F.
author_facet Sanchez, F. F.
Faganello, M. M.
Tanni, S. E. [UNESP]
Lucheta, P. A. [UNESP]
Padovani, C. R. [UNESP]
Godoy, I. [UNESP]
author_role author
author2 Faganello, M. M.
Tanni, S. E. [UNESP]
Lucheta, P. A. [UNESP]
Padovani, C. R. [UNESP]
Godoy, I. [UNESP]
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Centro Universitário Católico Salesiano Auxilium (UNISALESIANO)
Faculdades Adamantinenses Integradas (FAI)
Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Sanchez, F. F.
Faganello, M. M.
Tanni, S. E. [UNESP]
Lucheta, P. A. [UNESP]
Padovani, C. R. [UNESP]
Godoy, I. [UNESP]
dc.subject.por.fl_str_mv Pulmonary disease
Chronic obstructive pulmonary disease
St. George's Respiratory Questionnaire
Airways Questionnaire 20
Respiratory system
topic Pulmonary disease
Chronic obstructive pulmonary disease
St. George's Respiratory Questionnaire
Airways Questionnaire 20
Respiratory system
description Few studies have evaluated the relationship between Airways Questionnaire 20 (AQ20), a measure of the quality of life, scores and physiological outcomes or with systemic markers of disease in patients with chronic obstructive pulmonary disease (COPD). The aim of the present study was to investigate the relationship of forced expiratory volume in 1 s (FEV1), body mass index, fat-free mass index, 6-min walk test (6MWT) results, dyspnea sensation and peripheral oxygen saturation (SpO2) with the quality of life of COPD patients. Ninety-nine patients with COPD (mean age: 64.2 ± 9.2 years; mean FEV1: 60.4 ± 25.2% of predicted) were evaluated using spirometry, body composition measurement and the 6MWT. The baseline dyspnea index (BDI) and the Modified Medical Research Council (MMRC) scale were used to quantify dyspnea. Quality of life was assessed using the AQ20 and the St. George's Respiratory Questionnaire (SGRQ). The Charlson index was used to determine comorbidity. The body mass index/airflow obstruction/dyspnea/exercise capacity (BODE) index was also calculated. AQ20 and SGRQ scores correlated significantly with FEV1, SpO2, 6MWT, MMRC and BDI values as did with BODE index. In the multivariate analyses, MMRC or BDI were identified as predictors of AQ20 and SGRQ scores (P < 0.001 in all cases). Thus, the relationship between AQ20 and disease severity is similar to that described for SGRQ. Therefore, the AQ20, a simple and brief instrument, can be very useful to evaluate the general impact of disease when the time allotted for measurement of the quality of life is limited.
publishDate 2008
dc.date.none.fl_str_mv 2008-10-01
2014-05-20T13:47:51Z
2014-05-20T13:47:51Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0100-879X2008005000043
Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 41, n. 10, p. 860-865, 2008.
0100-879X
http://hdl.handle.net/11449/17054
10.1590/S0100-879X2008005000043
S0100-879X2008001000005
WOS:000261171400005
S0100-879X2008001000005.pdf
8727897080522289
url http://dx.doi.org/10.1590/S0100-879X2008005000043
http://hdl.handle.net/11449/17054
identifier_str_mv Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 41, n. 10, p. 860-865, 2008.
0100-879X
10.1590/S0100-879X2008005000043
S0100-879X2008001000005
WOS:000261171400005
S0100-879X2008001000005.pdf
8727897080522289
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Brazilian Journal of Medical and Biological Research
1.492
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 860-865
application/pdf
dc.publisher.none.fl_str_mv Associação Brasileira de Divulgação Científica (ABRADIC)
publisher.none.fl_str_mv Associação Brasileira de Divulgação Científica (ABRADIC)
dc.source.none.fl_str_mv SciELO
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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