On the mechanical biocompatibility of Ti-15Zr-based alloys for potential use as load-bearing implants

Detalhes bibliográficos
Autor(a) principal: Correa, D. R.N.
Data de Publicação: 2020
Outros Autores: Rocha, L. A. [UNESP], Donato, T. A.G. [UNESP], Sousa, K. S.J. [UNESP], Grandini, C. R. [UNESP], Afonso, C. R.M., Doi, H., Tsutsumi, Y., Hanawa, T.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
DOI: 10.1016/j.jmrt.2019.11.051
Texto Completo: http://dx.doi.org/10.1016/j.jmrt.2019.11.051
http://hdl.handle.net/11449/201396
Resumo: This study evaluated the mechanical properties and cytocompatibility of recently developed Ti-15Zr-based alloys with Mo addition for potential use as load-bearing implants. The phase composition and microstructure were changed by the alloying elements, being the β phase fully retained on the Ti-15Zr-10Mo and Ti-15Zr-15Mo samples. The TEM analysis showed that a small quantity of ω phase was precipitated on the samples with a high amount of Mo. Regarding the mechanical properties, the Ti-15Zr-10Mo sample presented high mechanical strength and large elongation (854»±»63»MPa and 18.7»±»2.8 %). However, the Ti-15Zr-15Mo sample exhibited better mechanical compatibility, due to its combination of low Young's modulus (75»±»1»GPa) and high Vickers microhardness (346»±»4»HV). Some dimple-type structures found along the fractured surface confirmed the ductile behavior of these samples. The MTT test indicated non-cytotoxic effects of all samples when in contact with osteoblastic cells (p»<»0.05). The wettability values of the samples were adequate for biomedical applications. The mechanical properties of the Ti-15Zr-15Mo sample were better than some commercial metallic biomaterials, which highlights its great potential for use as load-bearing implants.
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spelling On the mechanical biocompatibility of Ti-15Zr-based alloys for potential use as load-bearing implantsBiomaterialLoad-Bearing implantMechanical propertiesTi-Zr-Mo alloyThis study evaluated the mechanical properties and cytocompatibility of recently developed Ti-15Zr-based alloys with Mo addition for potential use as load-bearing implants. The phase composition and microstructure were changed by the alloying elements, being the β phase fully retained on the Ti-15Zr-10Mo and Ti-15Zr-15Mo samples. The TEM analysis showed that a small quantity of ω phase was precipitated on the samples with a high amount of Mo. Regarding the mechanical properties, the Ti-15Zr-10Mo sample presented high mechanical strength and large elongation (854»±»63»MPa and 18.7»±»2.8 %). However, the Ti-15Zr-15Mo sample exhibited better mechanical compatibility, due to its combination of low Young's modulus (75»±»1»GPa) and high Vickers microhardness (346»±»4»HV). Some dimple-type structures found along the fractured surface confirmed the ductile behavior of these samples. The MTT test indicated non-cytotoxic effects of all samples when in contact with osteoblastic cells (p»<»0.05). The wettability values of the samples were adequate for biomedical applications. The mechanical properties of the Ti-15Zr-15Mo sample were better than some commercial metallic biomaterials, which highlights its great potential for use as load-bearing implants.IFSP Federal Institute of Education Science and Technology Grupo de Pesquisa em Materiais Metálicos AvançadosIBTN/BR Institute of Biomaterials Tribocorrosion and Nanomedicine Brazilian BranchUNESP - Univ Estadual Paulista Laboratório de Anelasticidade e BiomateriaisUFSCar - University of São Carlos Department of Materials EngineeringInstitute of Biomaterials and Bioengineering Tokyo Medical and Dental UniversityResearch Center for Structural Materials National Institute for Materials ScienceUNESP - Univ Estadual Paulista Laboratório de Anelasticidade e BiomateriaisGrupo de Pesquisa em Materiais Metálicos AvançadosBrazilian BranchUniversidade Estadual Paulista (Unesp)Universidade Federal de São Carlos (UFSCar)Tokyo Medical and Dental UniversityNational Institute for Materials ScienceCorrea, D. R.N.Rocha, L. A. [UNESP]Donato, T. A.G. [UNESP]Sousa, K. S.J. [UNESP]Grandini, C. R. [UNESP]Afonso, C. R.M.Doi, H.Tsutsumi, Y.Hanawa, T.2020-12-12T02:31:26Z2020-12-12T02:31:26Z2020-03-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1241-1250http://dx.doi.org/10.1016/j.jmrt.2019.11.051Journal of Materials Research and Technology, v. 9, n. 2, p. 1241-1250, 2020.2238-7854http://hdl.handle.net/11449/20139610.1016/j.jmrt.2019.11.0512-s2.0-85076520755Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Materials Research and Technologyinfo:eu-repo/semantics/openAccess2024-04-25T17:39:23Zoai:repositorio.unesp.br:11449/201396Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T14:24:51.201384Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv On the mechanical biocompatibility of Ti-15Zr-based alloys for potential use as load-bearing implants
title On the mechanical biocompatibility of Ti-15Zr-based alloys for potential use as load-bearing implants
spellingShingle On the mechanical biocompatibility of Ti-15Zr-based alloys for potential use as load-bearing implants
On the mechanical biocompatibility of Ti-15Zr-based alloys for potential use as load-bearing implants
Correa, D. R.N.
Biomaterial
Load-Bearing implant
Mechanical properties
Ti-Zr-Mo alloy
Correa, D. R.N.
Biomaterial
Load-Bearing implant
Mechanical properties
Ti-Zr-Mo alloy
title_short On the mechanical biocompatibility of Ti-15Zr-based alloys for potential use as load-bearing implants
title_full On the mechanical biocompatibility of Ti-15Zr-based alloys for potential use as load-bearing implants
title_fullStr On the mechanical biocompatibility of Ti-15Zr-based alloys for potential use as load-bearing implants
On the mechanical biocompatibility of Ti-15Zr-based alloys for potential use as load-bearing implants
title_full_unstemmed On the mechanical biocompatibility of Ti-15Zr-based alloys for potential use as load-bearing implants
On the mechanical biocompatibility of Ti-15Zr-based alloys for potential use as load-bearing implants
title_sort On the mechanical biocompatibility of Ti-15Zr-based alloys for potential use as load-bearing implants
author Correa, D. R.N.
author_facet Correa, D. R.N.
Correa, D. R.N.
Rocha, L. A. [UNESP]
Donato, T. A.G. [UNESP]
Sousa, K. S.J. [UNESP]
Grandini, C. R. [UNESP]
Afonso, C. R.M.
Doi, H.
Tsutsumi, Y.
Hanawa, T.
Rocha, L. A. [UNESP]
Donato, T. A.G. [UNESP]
Sousa, K. S.J. [UNESP]
Grandini, C. R. [UNESP]
Afonso, C. R.M.
Doi, H.
Tsutsumi, Y.
Hanawa, T.
author_role author
author2 Rocha, L. A. [UNESP]
Donato, T. A.G. [UNESP]
Sousa, K. S.J. [UNESP]
Grandini, C. R. [UNESP]
Afonso, C. R.M.
Doi, H.
Tsutsumi, Y.
Hanawa, T.
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Grupo de Pesquisa em Materiais Metálicos Avançados
Brazilian Branch
Universidade Estadual Paulista (Unesp)
Universidade Federal de São Carlos (UFSCar)
Tokyo Medical and Dental University
National Institute for Materials Science
dc.contributor.author.fl_str_mv Correa, D. R.N.
Rocha, L. A. [UNESP]
Donato, T. A.G. [UNESP]
Sousa, K. S.J. [UNESP]
Grandini, C. R. [UNESP]
Afonso, C. R.M.
Doi, H.
Tsutsumi, Y.
Hanawa, T.
dc.subject.por.fl_str_mv Biomaterial
Load-Bearing implant
Mechanical properties
Ti-Zr-Mo alloy
topic Biomaterial
Load-Bearing implant
Mechanical properties
Ti-Zr-Mo alloy
description This study evaluated the mechanical properties and cytocompatibility of recently developed Ti-15Zr-based alloys with Mo addition for potential use as load-bearing implants. The phase composition and microstructure were changed by the alloying elements, being the β phase fully retained on the Ti-15Zr-10Mo and Ti-15Zr-15Mo samples. The TEM analysis showed that a small quantity of ω phase was precipitated on the samples with a high amount of Mo. Regarding the mechanical properties, the Ti-15Zr-10Mo sample presented high mechanical strength and large elongation (854»±»63»MPa and 18.7»±»2.8 %). However, the Ti-15Zr-15Mo sample exhibited better mechanical compatibility, due to its combination of low Young's modulus (75»±»1»GPa) and high Vickers microhardness (346»±»4»HV). Some dimple-type structures found along the fractured surface confirmed the ductile behavior of these samples. The MTT test indicated non-cytotoxic effects of all samples when in contact with osteoblastic cells (p»<»0.05). The wettability values of the samples were adequate for biomedical applications. The mechanical properties of the Ti-15Zr-15Mo sample were better than some commercial metallic biomaterials, which highlights its great potential for use as load-bearing implants.
publishDate 2020
dc.date.none.fl_str_mv 2020-12-12T02:31:26Z
2020-12-12T02:31:26Z
2020-03-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/j.jmrt.2019.11.051
Journal of Materials Research and Technology, v. 9, n. 2, p. 1241-1250, 2020.
2238-7854
http://hdl.handle.net/11449/201396
10.1016/j.jmrt.2019.11.051
2-s2.0-85076520755
url http://dx.doi.org/10.1016/j.jmrt.2019.11.051
http://hdl.handle.net/11449/201396
identifier_str_mv Journal of Materials Research and Technology, v. 9, n. 2, p. 1241-1250, 2020.
2238-7854
10.1016/j.jmrt.2019.11.051
2-s2.0-85076520755
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Journal of Materials Research and Technology
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1241-1250
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1822218519872274432
dc.identifier.doi.none.fl_str_mv 10.1016/j.jmrt.2019.11.051

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