The effect of intracuff alkalinized 2% lidocaine on emergence coughing, sore throat, and hoarseness in smokers
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/S0104-42302012000200023 http://hdl.handle.net/11449/29865 |
Resumo: | OBJECTIVE: We evaluated whether endotracheal tube (ETT) intracuff alkalinized lidocaine was superior to saline in blunting emergence coughing, postoperative sore throat, and hoarseness in smokers. METHODS: In our prospective, double-blind trial, we enrolled 50 smoking patients undergoing surgery under general anesthesia including nitrous oxide (N2O). Patients were randomly allocated to receive either ETT intracuff 2% lidocaine plus 8.4% sodium bicarbonate (L group), or ETT intracuff 0.9% saline (S group). The ETT cuff was inflated to achieve a cuff pressure that prevented air leak during positive pressure ventilation. Incidence of emergence coughing, sore throat, and hoarseness were analyzed. The volume of inflation solution, the intracuff pressure, the duration of anesthesia, the time elapsed to extubation after discontinuation of anesthesia, and the volume of the inflation solution and the air withdrawn from the ETT cuff were also recorded. RESULTS: Intracuff alkalinized 2% lidocaine was superior to saline in blunting emergence coughing (p < 0.001). The incidence of sore throat was significantly lower in the L group at the post-anesthesia care unit (PACU) (p = 0.02). However, at 24 hours after extubation, sore throat incidence was similar in both groups (p = 0.07). Incidence of hoarseness was similar in both groups. Intracuff pressure in the saline group increased with time while the intracuff pressure in the lidocaine group remained constant. CONCLUSION: The present study demonstrated that the intracuff alkalinized 2% lidocaine was superior to saline in decreasing the incidence of emergence coughing and sore throat during the postoperative period in smokers. |
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The effect of intracuff alkalinized 2% lidocaine on emergence coughing, sore throat, and hoarseness in smokersSmokinglidocainecoughhoarsenessnitrous oxideOBJECTIVE: We evaluated whether endotracheal tube (ETT) intracuff alkalinized lidocaine was superior to saline in blunting emergence coughing, postoperative sore throat, and hoarseness in smokers. METHODS: In our prospective, double-blind trial, we enrolled 50 smoking patients undergoing surgery under general anesthesia including nitrous oxide (N2O). Patients were randomly allocated to receive either ETT intracuff 2% lidocaine plus 8.4% sodium bicarbonate (L group), or ETT intracuff 0.9% saline (S group). The ETT cuff was inflated to achieve a cuff pressure that prevented air leak during positive pressure ventilation. Incidence of emergence coughing, sore throat, and hoarseness were analyzed. The volume of inflation solution, the intracuff pressure, the duration of anesthesia, the time elapsed to extubation after discontinuation of anesthesia, and the volume of the inflation solution and the air withdrawn from the ETT cuff were also recorded. RESULTS: Intracuff alkalinized 2% lidocaine was superior to saline in blunting emergence coughing (p < 0.001). The incidence of sore throat was significantly lower in the L group at the post-anesthesia care unit (PACU) (p = 0.02). However, at 24 hours after extubation, sore throat incidence was similar in both groups (p = 0.07). Incidence of hoarseness was similar in both groups. Intracuff pressure in the saline group increased with time while the intracuff pressure in the lidocaine group remained constant. CONCLUSION: The present study demonstrated that the intracuff alkalinized 2% lidocaine was superior to saline in decreasing the incidence of emergence coughing and sore throat during the postoperative period in smokers.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Universidade Estadual Paulista Faculdade de Medicina de BotucatuSanta Casa de Misericórdia de São PauloNaval Medical CenterUniversidade Estadual Paulista Faculdade de Medicina de BotucatuFAPESP: 05/55458-5Associação Médica BrasileiraUniversidade Estadual Paulista (Unesp)Santa Casa de Misericórdia de São PauloNaval Medical CenterNavarro, Laís Helena Camacho [UNESP]Lima, Rodrigo Moreira e [UNESP]Aguiar, Andressa SimõesBraz, José Reinaldo Cerqueira [UNESP]Carness, Jeffrey M.Módolo, Norma Sueli Pinheiro [UNESP]2014-05-20T15:16:01Z2014-05-20T15:16:01Z2012-04-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article248-253application/pdfhttp://dx.doi.org/10.1590/S0104-42302012000200023Revista da Associação Médica Brasileira. Associação Médica Brasileira, v. 58, n. 2, p. 248-253, 2012.0104-4230http://hdl.handle.net/11449/2986510.1590/S0104-42302012000200023S0104-42302012000200023WOS:000302926900025S0104-42302012000200023.pdf8223546475724058SciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengRevista da Associação Médica Brasileira0.7360,265info:eu-repo/semantics/openAccess2024-01-04T06:26:42Zoai:repositorio.unesp.br:11449/29865Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-01-04T06:26:42Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
The effect of intracuff alkalinized 2% lidocaine on emergence coughing, sore throat, and hoarseness in smokers |
title |
The effect of intracuff alkalinized 2% lidocaine on emergence coughing, sore throat, and hoarseness in smokers |
spellingShingle |
The effect of intracuff alkalinized 2% lidocaine on emergence coughing, sore throat, and hoarseness in smokers Navarro, Laís Helena Camacho [UNESP] Smoking lidocaine cough hoarseness nitrous oxide |
title_short |
The effect of intracuff alkalinized 2% lidocaine on emergence coughing, sore throat, and hoarseness in smokers |
title_full |
The effect of intracuff alkalinized 2% lidocaine on emergence coughing, sore throat, and hoarseness in smokers |
title_fullStr |
The effect of intracuff alkalinized 2% lidocaine on emergence coughing, sore throat, and hoarseness in smokers |
title_full_unstemmed |
The effect of intracuff alkalinized 2% lidocaine on emergence coughing, sore throat, and hoarseness in smokers |
title_sort |
The effect of intracuff alkalinized 2% lidocaine on emergence coughing, sore throat, and hoarseness in smokers |
author |
Navarro, Laís Helena Camacho [UNESP] |
author_facet |
Navarro, Laís Helena Camacho [UNESP] Lima, Rodrigo Moreira e [UNESP] Aguiar, Andressa Simões Braz, José Reinaldo Cerqueira [UNESP] Carness, Jeffrey M. Módolo, Norma Sueli Pinheiro [UNESP] |
author_role |
author |
author2 |
Lima, Rodrigo Moreira e [UNESP] Aguiar, Andressa Simões Braz, José Reinaldo Cerqueira [UNESP] Carness, Jeffrey M. Módolo, Norma Sueli Pinheiro [UNESP] |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Santa Casa de Misericórdia de São Paulo Naval Medical Center |
dc.contributor.author.fl_str_mv |
Navarro, Laís Helena Camacho [UNESP] Lima, Rodrigo Moreira e [UNESP] Aguiar, Andressa Simões Braz, José Reinaldo Cerqueira [UNESP] Carness, Jeffrey M. Módolo, Norma Sueli Pinheiro [UNESP] |
dc.subject.por.fl_str_mv |
Smoking lidocaine cough hoarseness nitrous oxide |
topic |
Smoking lidocaine cough hoarseness nitrous oxide |
description |
OBJECTIVE: We evaluated whether endotracheal tube (ETT) intracuff alkalinized lidocaine was superior to saline in blunting emergence coughing, postoperative sore throat, and hoarseness in smokers. METHODS: In our prospective, double-blind trial, we enrolled 50 smoking patients undergoing surgery under general anesthesia including nitrous oxide (N2O). Patients were randomly allocated to receive either ETT intracuff 2% lidocaine plus 8.4% sodium bicarbonate (L group), or ETT intracuff 0.9% saline (S group). The ETT cuff was inflated to achieve a cuff pressure that prevented air leak during positive pressure ventilation. Incidence of emergence coughing, sore throat, and hoarseness were analyzed. The volume of inflation solution, the intracuff pressure, the duration of anesthesia, the time elapsed to extubation after discontinuation of anesthesia, and the volume of the inflation solution and the air withdrawn from the ETT cuff were also recorded. RESULTS: Intracuff alkalinized 2% lidocaine was superior to saline in blunting emergence coughing (p < 0.001). The incidence of sore throat was significantly lower in the L group at the post-anesthesia care unit (PACU) (p = 0.02). However, at 24 hours after extubation, sore throat incidence was similar in both groups (p = 0.07). Incidence of hoarseness was similar in both groups. Intracuff pressure in the saline group increased with time while the intracuff pressure in the lidocaine group remained constant. CONCLUSION: The present study demonstrated that the intracuff alkalinized 2% lidocaine was superior to saline in decreasing the incidence of emergence coughing and sore throat during the postoperative period in smokers. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-04-01 2014-05-20T15:16:01Z 2014-05-20T15:16:01Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S0104-42302012000200023 Revista da Associação Médica Brasileira. Associação Médica Brasileira, v. 58, n. 2, p. 248-253, 2012. 0104-4230 http://hdl.handle.net/11449/29865 10.1590/S0104-42302012000200023 S0104-42302012000200023 WOS:000302926900025 S0104-42302012000200023.pdf 8223546475724058 |
url |
http://dx.doi.org/10.1590/S0104-42302012000200023 http://hdl.handle.net/11449/29865 |
identifier_str_mv |
Revista da Associação Médica Brasileira. Associação Médica Brasileira, v. 58, n. 2, p. 248-253, 2012. 0104-4230 10.1590/S0104-42302012000200023 S0104-42302012000200023 WOS:000302926900025 S0104-42302012000200023.pdf 8223546475724058 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Revista da Associação Médica Brasileira 0.736 0,265 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
248-253 application/pdf |
dc.publisher.none.fl_str_mv |
Associação Médica Brasileira |
publisher.none.fl_str_mv |
Associação Médica Brasileira |
dc.source.none.fl_str_mv |
SciELO reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1799965513970876416 |