Rural Triatoma rubrovaria from southern Brazil Harbors Trypanosoma cruzi of lineage IIc
Autor(a) principal: | |
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Data de Publicação: | 2008 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.4269/ajtmh.2008.79.427 http://hdl.handle.net/11449/219476 |
Resumo: | Triatoma infestans, the main vector of Chagas disease, has nearly been eliminated from Brazil. Nevertheless, other triatominae species are involved in the domiciliation process, including Triatoma rubrovaria in Rio Grande do Sul State (RS). Previous studies showed that 1.6% of the T. rubrovaria specimens collected at the rural district of Quaraí, RS, were naturally infected by Trypanosoma cruzi. In this study, five T. cruzi isolates obtained from infected triatomines were characterized molecularly and biologically. Genotyping of the T. cruzi isolates showed that they belong to lineage IIc of T. cruzi (TCIIc). Biological characterization showed miotropism and myositis during acute and chronic phases of infection, respectively. Virulence and mortality rates were variable among isolates. To our knowledge, this study corresponds to the first characterization of T. cruzi isolates from T. rubrovaria and the first description of TCIIc in the sylvatic cycle of T. cruzi from the southern region of Brazil. Copyright © 2008 by The American Society of Tropical Medicine and Hygiene. |
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Rural Triatoma rubrovaria from southern Brazil Harbors Trypanosoma cruzi of lineage IIcTriatoma infestans, the main vector of Chagas disease, has nearly been eliminated from Brazil. Nevertheless, other triatominae species are involved in the domiciliation process, including Triatoma rubrovaria in Rio Grande do Sul State (RS). Previous studies showed that 1.6% of the T. rubrovaria specimens collected at the rural district of Quaraí, RS, were naturally infected by Trypanosoma cruzi. In this study, five T. cruzi isolates obtained from infected triatomines were characterized molecularly and biologically. Genotyping of the T. cruzi isolates showed that they belong to lineage IIc of T. cruzi (TCIIc). Biological characterization showed miotropism and myositis during acute and chronic phases of infection, respectively. Virulence and mortality rates were variable among isolates. To our knowledge, this study corresponds to the first characterization of T. cruzi isolates from T. rubrovaria and the first description of TCIIc in the sylvatic cycle of T. cruzi from the southern region of Brazil. Copyright © 2008 by The American Society of Tropical Medicine and Hygiene.Discipline of Molecular Biology Marilia Medical School, Av. Monte Carmelo 800, CEP 17519-030, Marília SPDiscipline of Parasitology Marília Medical School, Av. Monte Carmelo, 800, CEP 17519-030, Marília, São PauloDepartment of Parasitology Institute of Medical Sciences University of São Paulo, Av. Prof. Lineu Prestes 1374, CEP 05508-900, São PauloDepartment of Parasitology Pharmaceutical Sciences Faculty University of the State of São Paulo, Rodovia Araraquara-Jaú Km 01, CEP 14801-902, Araraquara, São PauloMarilia Medical SchoolMarília Medical SchoolUniversidade de São Paulo (USP)University of the State of São PauloMartins, Luciamáre P. A.Marcili, ArleiCastanho, Roberto E. P.Therezo, Altino L. S.De Oliveira, Janaína C. P.Suzuki, Rodrigo B.Teixeira, Marta M. G.Da Rosa, João A.Sperança, Márcia A.2022-04-28T18:55:46Z2022-04-28T18:55:46Z2008-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article427-434http://dx.doi.org/10.4269/ajtmh.2008.79.427American Journal of Tropical Medicine and Hygiene, v. 79, n. 3, p. 427-434, 2008.0002-9637http://hdl.handle.net/11449/21947610.4269/ajtmh.2008.79.4272-s2.0-52349106619Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengAmerican Journal of Tropical Medicine and Hygieneinfo:eu-repo/semantics/openAccess2022-04-28T18:55:46Zoai:repositorio.unesp.br:11449/219476Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462022-04-28T18:55:46Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Rural Triatoma rubrovaria from southern Brazil Harbors Trypanosoma cruzi of lineage IIc |
title |
Rural Triatoma rubrovaria from southern Brazil Harbors Trypanosoma cruzi of lineage IIc |
spellingShingle |
Rural Triatoma rubrovaria from southern Brazil Harbors Trypanosoma cruzi of lineage IIc Martins, Luciamáre P. A. |
title_short |
Rural Triatoma rubrovaria from southern Brazil Harbors Trypanosoma cruzi of lineage IIc |
title_full |
Rural Triatoma rubrovaria from southern Brazil Harbors Trypanosoma cruzi of lineage IIc |
title_fullStr |
Rural Triatoma rubrovaria from southern Brazil Harbors Trypanosoma cruzi of lineage IIc |
title_full_unstemmed |
Rural Triatoma rubrovaria from southern Brazil Harbors Trypanosoma cruzi of lineage IIc |
title_sort |
Rural Triatoma rubrovaria from southern Brazil Harbors Trypanosoma cruzi of lineage IIc |
author |
Martins, Luciamáre P. A. |
author_facet |
Martins, Luciamáre P. A. Marcili, Arlei Castanho, Roberto E. P. Therezo, Altino L. S. De Oliveira, Janaína C. P. Suzuki, Rodrigo B. Teixeira, Marta M. G. Da Rosa, João A. Sperança, Márcia A. |
author_role |
author |
author2 |
Marcili, Arlei Castanho, Roberto E. P. Therezo, Altino L. S. De Oliveira, Janaína C. P. Suzuki, Rodrigo B. Teixeira, Marta M. G. Da Rosa, João A. Sperança, Márcia A. |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
Marilia Medical School Marília Medical School Universidade de São Paulo (USP) University of the State of São Paulo |
dc.contributor.author.fl_str_mv |
Martins, Luciamáre P. A. Marcili, Arlei Castanho, Roberto E. P. Therezo, Altino L. S. De Oliveira, Janaína C. P. Suzuki, Rodrigo B. Teixeira, Marta M. G. Da Rosa, João A. Sperança, Márcia A. |
description |
Triatoma infestans, the main vector of Chagas disease, has nearly been eliminated from Brazil. Nevertheless, other triatominae species are involved in the domiciliation process, including Triatoma rubrovaria in Rio Grande do Sul State (RS). Previous studies showed that 1.6% of the T. rubrovaria specimens collected at the rural district of Quaraí, RS, were naturally infected by Trypanosoma cruzi. In this study, five T. cruzi isolates obtained from infected triatomines were characterized molecularly and biologically. Genotyping of the T. cruzi isolates showed that they belong to lineage IIc of T. cruzi (TCIIc). Biological characterization showed miotropism and myositis during acute and chronic phases of infection, respectively. Virulence and mortality rates were variable among isolates. To our knowledge, this study corresponds to the first characterization of T. cruzi isolates from T. rubrovaria and the first description of TCIIc in the sylvatic cycle of T. cruzi from the southern region of Brazil. Copyright © 2008 by The American Society of Tropical Medicine and Hygiene. |
publishDate |
2008 |
dc.date.none.fl_str_mv |
2008-01-01 2022-04-28T18:55:46Z 2022-04-28T18:55:46Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.4269/ajtmh.2008.79.427 American Journal of Tropical Medicine and Hygiene, v. 79, n. 3, p. 427-434, 2008. 0002-9637 http://hdl.handle.net/11449/219476 10.4269/ajtmh.2008.79.427 2-s2.0-52349106619 |
url |
http://dx.doi.org/10.4269/ajtmh.2008.79.427 http://hdl.handle.net/11449/219476 |
identifier_str_mv |
American Journal of Tropical Medicine and Hygiene, v. 79, n. 3, p. 427-434, 2008. 0002-9637 10.4269/ajtmh.2008.79.427 2-s2.0-52349106619 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
American Journal of Tropical Medicine and Hygiene |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
427-434 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
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1799964738305654784 |