On-line monitoring of electrochemical degradation of paracetamol through a biomimetic sensor
Autor(a) principal: | |
---|---|
Data de Publicação: | 2011 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://www.hindawi.com/journals/ijelc/2011/171389/ http://hdl.handle.net/11449/123515 |
Resumo: | This paper reports, for the first time, the online monitoring to the electrochemical degradation of the paracetamol using a biomimetic sensor coupled to a Flow Injection Analysis (FIA) system. The electrochemical degradation of the drug was carried out in aqueous medium using a flow-by reactor with a DSA anode. The process efficiency was monitored at real time by the biomimetic sensor constructed by modifying a glassy carbon electrode with a Nafion membrane doped with iron tetrapyridinoporphyrazine (FeTPyPz). Simultaneously, we carried out off-line analysis by liquid chromatography (HPLC) during the experiments in order to validate the proposed system. In addition, to investigate the degradation products of the paracetamol electrolysis, we used the techniques of UPLC/MS and GC/MS. |
id |
UNSP_5f4f4a53053142774bbf8a14a140904d |
---|---|
oai_identifier_str |
oai:repositorio.unesp.br:11449/123515 |
network_acronym_str |
UNSP |
network_name_str |
Repositório Institucional da UNESP |
repository_id_str |
2946 |
spelling |
On-line monitoring of electrochemical degradation of paracetamol through a biomimetic sensorThis paper reports, for the first time, the online monitoring to the electrochemical degradation of the paracetamol using a biomimetic sensor coupled to a Flow Injection Analysis (FIA) system. The electrochemical degradation of the drug was carried out in aqueous medium using a flow-by reactor with a DSA anode. The process efficiency was monitored at real time by the biomimetic sensor constructed by modifying a glassy carbon electrode with a Nafion membrane doped with iron tetrapyridinoporphyrazine (FeTPyPz). Simultaneously, we carried out off-line analysis by liquid chromatography (HPLC) during the experiments in order to validate the proposed system. In addition, to investigate the degradation products of the paracetamol electrolysis, we used the techniques of UPLC/MS and GC/MS.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Universidade Estadual Paulista Júlio de Mesquita Filho, Instituto de Química de Araraquara, Araraquara, Rua Professor Francisco Degni, 55, Jardim Quitandinha, CEP 14800060, SP, BrasilUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Química Analítica, Instituto de Química de AraraquaraFAPESP: 2008/00303-5FAPESP: 2008/05899-3Universidade Estadual Paulista (Unesp)Universidade de São Paulo (USP)Universidade Estadual de Campinas (UNICAMP)Oliveira, Mariana Calora Quintino de [UNESP]Lanza, Marcos Roberto VasconcelosJara, José Luis PazSotomayor, Maria Del Pilar Taboada [UNESP]2015-05-15T13:30:20Z2015-05-15T13:30:20Z2011info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1-11application/pdfhttp://www.hindawi.com/journals/ijelc/2011/171389/International Journal of Electrochemistry, v. 2011, p. 1-11, 2011.2090-3529http://hdl.handle.net/11449/12351510.4061/2011/171389ISSN2090-3529-2011-2011-01-11.pdf2933194342093387746141967186542333580269229310432933194342093387Currículo Lattesreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengInternational Journal of Electrochemistryinfo:eu-repo/semantics/openAccess2023-11-09T06:10:43Zoai:repositorio.unesp.br:11449/123515Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T17:13:52.935106Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
On-line monitoring of electrochemical degradation of paracetamol through a biomimetic sensor |
title |
On-line monitoring of electrochemical degradation of paracetamol through a biomimetic sensor |
spellingShingle |
On-line monitoring of electrochemical degradation of paracetamol through a biomimetic sensor Oliveira, Mariana Calora Quintino de [UNESP] |
title_short |
On-line monitoring of electrochemical degradation of paracetamol through a biomimetic sensor |
title_full |
On-line monitoring of electrochemical degradation of paracetamol through a biomimetic sensor |
title_fullStr |
On-line monitoring of electrochemical degradation of paracetamol through a biomimetic sensor |
title_full_unstemmed |
On-line monitoring of electrochemical degradation of paracetamol through a biomimetic sensor |
title_sort |
On-line monitoring of electrochemical degradation of paracetamol through a biomimetic sensor |
author |
Oliveira, Mariana Calora Quintino de [UNESP] |
author_facet |
Oliveira, Mariana Calora Quintino de [UNESP] Lanza, Marcos Roberto Vasconcelos Jara, José Luis Paz Sotomayor, Maria Del Pilar Taboada [UNESP] |
author_role |
author |
author2 |
Lanza, Marcos Roberto Vasconcelos Jara, José Luis Paz Sotomayor, Maria Del Pilar Taboada [UNESP] |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Universidade de São Paulo (USP) Universidade Estadual de Campinas (UNICAMP) |
dc.contributor.author.fl_str_mv |
Oliveira, Mariana Calora Quintino de [UNESP] Lanza, Marcos Roberto Vasconcelos Jara, José Luis Paz Sotomayor, Maria Del Pilar Taboada [UNESP] |
description |
This paper reports, for the first time, the online monitoring to the electrochemical degradation of the paracetamol using a biomimetic sensor coupled to a Flow Injection Analysis (FIA) system. The electrochemical degradation of the drug was carried out in aqueous medium using a flow-by reactor with a DSA anode. The process efficiency was monitored at real time by the biomimetic sensor constructed by modifying a glassy carbon electrode with a Nafion membrane doped with iron tetrapyridinoporphyrazine (FeTPyPz). Simultaneously, we carried out off-line analysis by liquid chromatography (HPLC) during the experiments in order to validate the proposed system. In addition, to investigate the degradation products of the paracetamol electrolysis, we used the techniques of UPLC/MS and GC/MS. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011 2015-05-15T13:30:20Z 2015-05-15T13:30:20Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.hindawi.com/journals/ijelc/2011/171389/ International Journal of Electrochemistry, v. 2011, p. 1-11, 2011. 2090-3529 http://hdl.handle.net/11449/123515 10.4061/2011/171389 ISSN2090-3529-2011-2011-01-11.pdf 2933194342093387 7461419671865423 3358026922931043 2933194342093387 |
url |
http://www.hindawi.com/journals/ijelc/2011/171389/ http://hdl.handle.net/11449/123515 |
identifier_str_mv |
International Journal of Electrochemistry, v. 2011, p. 1-11, 2011. 2090-3529 10.4061/2011/171389 ISSN2090-3529-2011-2011-01-11.pdf 2933194342093387 7461419671865423 3358026922931043 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
International Journal of Electrochemistry |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
1-11 application/pdf |
dc.source.none.fl_str_mv |
Currículo Lattes reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128776491499520 |