Portable and simple electroanalytical procedure for simultaneous detection of dipyrone and norfloxacin with disposable commercial electrodes in water and organic fertilizers
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1007/s11581-022-04689-y http://hdl.handle.net/11449/240534 |
Resumo: | The increasing presence of drugs in the environment has caused great concern in recent years due to their adverse side effects, whether related to animals or humans. In this aspect, the search for methods capable of controlling and monitoring these emerging contaminants in a simple, fast, low-cost, and environmentally friendly way becomes a very important research area that can assist in the preservation of the environment and human health. Therefore, the present work aims to propose for the first time the simultaneous electroanalytical quantification of two drugs, extremely consumed worldwide (dipyrone and norfloxacin) of different classes (analgesic and antibiotic), in environmental and biological samples (organic fertilizer, water, and urine). For this, a commercial disposable boron-doped diamond electrochemical sensor (screen-printed electrodes) was used, in conjunction with portable equipment. A simple procedure was fully optimized for the determination of these two analytes by square wave voltammetry (SWV), including the choice of the best working pH and operational parameters of the technique. The SWV operational parameters were optimized using unified multivariate optimization for the best analysis condition for both drugs. The proposed method presents limit of detection of 0.30 and 0.40 µmol L−1 for dipyrone and norfloxacin, respectively. The analysis of the samples showed a recovery ranging from 94.0 to 105.0%, demonstrating that the method is suitable for performing the simultaneous determination in a few seconds, with no need for sample pre-treatment steps, and in a sustainable way. |
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Portable and simple electroanalytical procedure for simultaneous detection of dipyrone and norfloxacin with disposable commercial electrodes in water and organic fertilizersDrugsElectrochemistryEmerging contaminantsOrganic fertilizerScreen-printed electrodeThe increasing presence of drugs in the environment has caused great concern in recent years due to their adverse side effects, whether related to animals or humans. In this aspect, the search for methods capable of controlling and monitoring these emerging contaminants in a simple, fast, low-cost, and environmentally friendly way becomes a very important research area that can assist in the preservation of the environment and human health. Therefore, the present work aims to propose for the first time the simultaneous electroanalytical quantification of two drugs, extremely consumed worldwide (dipyrone and norfloxacin) of different classes (analgesic and antibiotic), in environmental and biological samples (organic fertilizer, water, and urine). For this, a commercial disposable boron-doped diamond electrochemical sensor (screen-printed electrodes) was used, in conjunction with portable equipment. A simple procedure was fully optimized for the determination of these two analytes by square wave voltammetry (SWV), including the choice of the best working pH and operational parameters of the technique. The SWV operational parameters were optimized using unified multivariate optimization for the best analysis condition for both drugs. The proposed method presents limit of detection of 0.30 and 0.40 µmol L−1 for dipyrone and norfloxacin, respectively. The analysis of the samples showed a recovery ranging from 94.0 to 105.0%, demonstrating that the method is suitable for performing the simultaneous determination in a few seconds, with no need for sample pre-treatment steps, and in a sustainable way.Chemistry Department Federal University of Espírito Santo, Espírito SantoLaboratory of Sensors Nanomedicine and Nanostructured Materials Federal University of São Carlos, São PauloChemistry Institute Federal University of Rio de JaneiroNational Institute for Alternative Technologies of Detection Toxicological Evaluation and Removal of Micropollutants and Radioactives Institute of Chemistry Paulista State University - Júlio de Mesquita Filho, São PauloNational Institute for Alternative Technologies of Detection Toxicological Evaluation and Removal of Micropollutants and Radioactives Institute of Chemistry Paulista State University - Júlio de Mesquita Filho, São PauloFederal University of Espírito SantoUniversidade Federal de São Carlos (UFSCar)Federal University of Rio de JaneiroUniversidade Estadual Paulista (UNESP)Silva, Luiz R. G.Rodrigues, José G. A. [UNESP]Vasconcellos, Maria de L. S.Ribeiro, Emerson S. [UNESP]D’Elia, Eliane [UNESP]Ferreira, Rafael de Q.2023-03-01T20:21:29Z2023-03-01T20:21:29Z2022-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1007/s11581-022-04689-yIonics.1862-07600947-7047http://hdl.handle.net/11449/24053410.1007/s11581-022-04689-y2-s2.0-85134822472Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengIonicsinfo:eu-repo/semantics/openAccess2023-03-01T20:21:30Zoai:repositorio.unesp.br:11449/240534Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T22:08:27.589152Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Portable and simple electroanalytical procedure for simultaneous detection of dipyrone and norfloxacin with disposable commercial electrodes in water and organic fertilizers |
title |
Portable and simple electroanalytical procedure for simultaneous detection of dipyrone and norfloxacin with disposable commercial electrodes in water and organic fertilizers |
spellingShingle |
Portable and simple electroanalytical procedure for simultaneous detection of dipyrone and norfloxacin with disposable commercial electrodes in water and organic fertilizers Silva, Luiz R. G. Drugs Electrochemistry Emerging contaminants Organic fertilizer Screen-printed electrode |
title_short |
Portable and simple electroanalytical procedure for simultaneous detection of dipyrone and norfloxacin with disposable commercial electrodes in water and organic fertilizers |
title_full |
Portable and simple electroanalytical procedure for simultaneous detection of dipyrone and norfloxacin with disposable commercial electrodes in water and organic fertilizers |
title_fullStr |
Portable and simple electroanalytical procedure for simultaneous detection of dipyrone and norfloxacin with disposable commercial electrodes in water and organic fertilizers |
title_full_unstemmed |
Portable and simple electroanalytical procedure for simultaneous detection of dipyrone and norfloxacin with disposable commercial electrodes in water and organic fertilizers |
title_sort |
Portable and simple electroanalytical procedure for simultaneous detection of dipyrone and norfloxacin with disposable commercial electrodes in water and organic fertilizers |
author |
Silva, Luiz R. G. |
author_facet |
Silva, Luiz R. G. Rodrigues, José G. A. [UNESP] Vasconcellos, Maria de L. S. Ribeiro, Emerson S. [UNESP] D’Elia, Eliane [UNESP] Ferreira, Rafael de Q. |
author_role |
author |
author2 |
Rodrigues, José G. A. [UNESP] Vasconcellos, Maria de L. S. Ribeiro, Emerson S. [UNESP] D’Elia, Eliane [UNESP] Ferreira, Rafael de Q. |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Federal University of Espírito Santo Universidade Federal de São Carlos (UFSCar) Federal University of Rio de Janeiro Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Silva, Luiz R. G. Rodrigues, José G. A. [UNESP] Vasconcellos, Maria de L. S. Ribeiro, Emerson S. [UNESP] D’Elia, Eliane [UNESP] Ferreira, Rafael de Q. |
dc.subject.por.fl_str_mv |
Drugs Electrochemistry Emerging contaminants Organic fertilizer Screen-printed electrode |
topic |
Drugs Electrochemistry Emerging contaminants Organic fertilizer Screen-printed electrode |
description |
The increasing presence of drugs in the environment has caused great concern in recent years due to their adverse side effects, whether related to animals or humans. In this aspect, the search for methods capable of controlling and monitoring these emerging contaminants in a simple, fast, low-cost, and environmentally friendly way becomes a very important research area that can assist in the preservation of the environment and human health. Therefore, the present work aims to propose for the first time the simultaneous electroanalytical quantification of two drugs, extremely consumed worldwide (dipyrone and norfloxacin) of different classes (analgesic and antibiotic), in environmental and biological samples (organic fertilizer, water, and urine). For this, a commercial disposable boron-doped diamond electrochemical sensor (screen-printed electrodes) was used, in conjunction with portable equipment. A simple procedure was fully optimized for the determination of these two analytes by square wave voltammetry (SWV), including the choice of the best working pH and operational parameters of the technique. The SWV operational parameters were optimized using unified multivariate optimization for the best analysis condition for both drugs. The proposed method presents limit of detection of 0.30 and 0.40 µmol L−1 for dipyrone and norfloxacin, respectively. The analysis of the samples showed a recovery ranging from 94.0 to 105.0%, demonstrating that the method is suitable for performing the simultaneous determination in a few seconds, with no need for sample pre-treatment steps, and in a sustainable way. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-01-01 2023-03-01T20:21:29Z 2023-03-01T20:21:29Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1007/s11581-022-04689-y Ionics. 1862-0760 0947-7047 http://hdl.handle.net/11449/240534 10.1007/s11581-022-04689-y 2-s2.0-85134822472 |
url |
http://dx.doi.org/10.1007/s11581-022-04689-y http://hdl.handle.net/11449/240534 |
identifier_str_mv |
Ionics. 1862-0760 0947-7047 10.1007/s11581-022-04689-y 2-s2.0-85134822472 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Ionics |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
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1808129396154826752 |