Beta therapy with 90 strontium as single modality therapy for canine squamous cell carcinoma in third eyelid

Detalhes bibliográficos
Autor(a) principal: Andrade, Alexandre Lima de [UNESP]
Data de Publicação: 2015
Outros Autores: Fernandes, Marco Antônio Rodrigues [UNESP], Sakamoto, Silmara Sanae [UNESP], Luvizotto, Maria Cecília Rui [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782015000601066&tlng=
http://hdl.handle.net/11449/127321
Resumo: The purpose was to evaluate the effectiveness of beta-radiation with strontium-90 as single modality treatment of canine third eyelid squamous cell carcinoma (SCC). Nine dogs diagnosed with third eyelid SCC were treated with strontium-90. Radiation therapy was administered in four fractions of 100cGy per site every four days and at a depth of 0.2cm (Strontium-90 build' up) in each fraction. Radiation with beta therapy was well tolerated in all animals with no occurrence of radiation induced cataracts. In all cases, there were increased signs of conjunctival inflammation around the mass, which subsided with topical anti-inflammatory. Two dogs required surgical treatment for local tumor recurrence at 150 days and 352 days. In the remaining seven cases, disease free interval ranged from 1239 days to 2555 days. Beta therapy using 90Sr may be a valid alternative for the treatment of third eyelid SCC in dogs
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spelling Beta therapy with 90 strontium as single modality therapy for canine squamous cell carcinoma in third eyelidBetaterapia com estrôncio-90 como modalidade única de terapia para o carcinoma de células escamosas na terceira pálpebra em cãesBeta-radiationRadiotherapyOcular tumorAdnexa ocularDogsRadiação betaRadioterapiaTumor ocularAnexo ocularCãesThe purpose was to evaluate the effectiveness of beta-radiation with strontium-90 as single modality treatment of canine third eyelid squamous cell carcinoma (SCC). Nine dogs diagnosed with third eyelid SCC were treated with strontium-90. Radiation therapy was administered in four fractions of 100cGy per site every four days and at a depth of 0.2cm (Strontium-90 build' up) in each fraction. Radiation with beta therapy was well tolerated in all animals with no occurrence of radiation induced cataracts. In all cases, there were increased signs of conjunctival inflammation around the mass, which subsided with topical anti-inflammatory. Two dogs required surgical treatment for local tumor recurrence at 150 days and 352 days. In the remaining seven cases, disease free interval ranged from 1239 days to 2555 days. Beta therapy using 90Sr may be a valid alternative for the treatment of third eyelid SCC in dogsO objetivo foi avaliar a eficácia da betaterapia com estrôncio-90 como modalidade única de tratamento em carcinomas de células escamosas (CEC) da terceira pálpebra de cães. Nove cães foram diagnosticados com CEC de terceira pálpebra, que foram tratados com estrôncio-90. A radioterapia foi administrada em quatro frações de 100cGy por local, a cada quatro dias e a uma profundidade de 0,2cm em cada fração. A betaterapia foi bem tolerada por todos os animais, sem ocorrência de catarata induzida pela radiação. Em todos os casos, houve um aumento dos sinais de inflamação da conjuntiva ao redor da neoformação, as quais cederam com o uso de anti-inflamatório tópico. Em dois cães houve a necessidade de tratamento cirúrgico, pois houve recorrência local do tumor aos 150 dias e aos 352 dias. Nos outros sete casos, o intervalo livre de doença variou entre 1.239 dias e 2.555 dias. Betaterapia usando 90Sr pode ser uma alternativa válida para o tratamento do CEC da terceira pálpebra em cãesUniversidade Estadual Paulista Júlio de Mesquita Filho Departamento de Clínica, Cirurgia e Reprodução Animal Faculdade de Medicina Veterinária de AraçatubaUNESP Departamento de Dermatologia e Radioterapia Faculdade de Medicina de BotucatuUNESP FMVAUniversidade Estadual Paulista Júlio de Mesquita Filho Departamento de Clínica, Cirurgia e Reprodução Animal Faculdade de Medicina Veterinária de AraçatubaUNESP Departamento de Dermatologia e Radioterapia Faculdade de Medicina de BotucatuUNESP FMVAUniversidade Federal de Santa MariaUniversidade Estadual Paulista (Unesp)Andrade, Alexandre Lima de [UNESP]Fernandes, Marco Antônio Rodrigues [UNESP]Sakamoto, Silmara Sanae [UNESP]Luvizotto, Maria Cecília Rui [UNESP]2015-08-26T19:19:11Z2015-08-26T19:19:11Z2015-06-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1066-1072application/pdfhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782015000601066&tlng=Ciência Rural, v. 45, n. 6, p. 1066-1072, 2015.0103-8478http://hdl.handle.net/11449/12732110.1590/0103-8478cr20140918S0103-84782015000601066S0103-84782015000601066.pdf640417649530617145846749099524772307939425313065SciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengCiência Rural0.5250,337info:eu-repo/semantics/openAccess2024-09-04T18:03:44Zoai:repositorio.unesp.br:11449/127321Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-04T18:03:44Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Beta therapy with 90 strontium as single modality therapy for canine squamous cell carcinoma in third eyelid
Betaterapia com estrôncio-90 como modalidade única de terapia para o carcinoma de células escamosas na terceira pálpebra em cães
title Beta therapy with 90 strontium as single modality therapy for canine squamous cell carcinoma in third eyelid
spellingShingle Beta therapy with 90 strontium as single modality therapy for canine squamous cell carcinoma in third eyelid
Andrade, Alexandre Lima de [UNESP]
Beta-radiation
Radiotherapy
Ocular tumor
Adnexa ocular
Dogs
Radiação beta
Radioterapia
Tumor ocular
Anexo ocular
Cães
title_short Beta therapy with 90 strontium as single modality therapy for canine squamous cell carcinoma in third eyelid
title_full Beta therapy with 90 strontium as single modality therapy for canine squamous cell carcinoma in third eyelid
title_fullStr Beta therapy with 90 strontium as single modality therapy for canine squamous cell carcinoma in third eyelid
title_full_unstemmed Beta therapy with 90 strontium as single modality therapy for canine squamous cell carcinoma in third eyelid
title_sort Beta therapy with 90 strontium as single modality therapy for canine squamous cell carcinoma in third eyelid
author Andrade, Alexandre Lima de [UNESP]
author_facet Andrade, Alexandre Lima de [UNESP]
Fernandes, Marco Antônio Rodrigues [UNESP]
Sakamoto, Silmara Sanae [UNESP]
Luvizotto, Maria Cecília Rui [UNESP]
author_role author
author2 Fernandes, Marco Antônio Rodrigues [UNESP]
Sakamoto, Silmara Sanae [UNESP]
Luvizotto, Maria Cecília Rui [UNESP]
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Andrade, Alexandre Lima de [UNESP]
Fernandes, Marco Antônio Rodrigues [UNESP]
Sakamoto, Silmara Sanae [UNESP]
Luvizotto, Maria Cecília Rui [UNESP]
dc.subject.por.fl_str_mv Beta-radiation
Radiotherapy
Ocular tumor
Adnexa ocular
Dogs
Radiação beta
Radioterapia
Tumor ocular
Anexo ocular
Cães
topic Beta-radiation
Radiotherapy
Ocular tumor
Adnexa ocular
Dogs
Radiação beta
Radioterapia
Tumor ocular
Anexo ocular
Cães
description The purpose was to evaluate the effectiveness of beta-radiation with strontium-90 as single modality treatment of canine third eyelid squamous cell carcinoma (SCC). Nine dogs diagnosed with third eyelid SCC were treated with strontium-90. Radiation therapy was administered in four fractions of 100cGy per site every four days and at a depth of 0.2cm (Strontium-90 build' up) in each fraction. Radiation with beta therapy was well tolerated in all animals with no occurrence of radiation induced cataracts. In all cases, there were increased signs of conjunctival inflammation around the mass, which subsided with topical anti-inflammatory. Two dogs required surgical treatment for local tumor recurrence at 150 days and 352 days. In the remaining seven cases, disease free interval ranged from 1239 days to 2555 days. Beta therapy using 90Sr may be a valid alternative for the treatment of third eyelid SCC in dogs
publishDate 2015
dc.date.none.fl_str_mv 2015-08-26T19:19:11Z
2015-08-26T19:19:11Z
2015-06-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782015000601066&tlng=
Ciência Rural, v. 45, n. 6, p. 1066-1072, 2015.
0103-8478
http://hdl.handle.net/11449/127321
10.1590/0103-8478cr20140918
S0103-84782015000601066
S0103-84782015000601066.pdf
6404176495306171
4584674909952477
2307939425313065
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782015000601066&tlng=
http://hdl.handle.net/11449/127321
identifier_str_mv Ciência Rural, v. 45, n. 6, p. 1066-1072, 2015.
0103-8478
10.1590/0103-8478cr20140918
S0103-84782015000601066
S0103-84782015000601066.pdf
6404176495306171
4584674909952477
2307939425313065
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Ciência Rural
0.525
0,337
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1066-1072
application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Santa Maria
publisher.none.fl_str_mv Universidade Federal de Santa Maria
dc.source.none.fl_str_mv SciELO
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv repositoriounesp@unesp.br
_version_ 1810021377195900928

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