Contamination index. A novel parameter for metal and pesticide analyses in maternal blood and umbilical cord
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/S0102-865020160070000010 http://hdl.handle.net/11449/173311 |
Resumo: | PURPOSE: To evaluate the contamination index of metals and pesticides in pregnant women, and to relate this to perinatal outcomes. METHODS: Descriptive, retrospective, exploratory study, developed from existing secondary data analyses at Level III maternity center. A total of 40 mothers with their newborns (NB), living in a rural area in Botucatu-Brazil and surrounding region. Blood samples from mothers and newborn were collected to determine the total contamination index for metals and pesticides. The concentrations of each metal and each pesticide were determined in blood samples of mothers and their newborns by Rudge’s results. After obtaining these concentrations, the total contamination index in mother and NB was calculated, along with its correlation with clinical parameters of NB. RESULTS: There was no correlation (p> 0.05) between maternal contamination index with NB clinical parameters, and NB contamination index versus NB clinical parameters. CONCLUSION: The maternal contamination index of metals and pesticides was not related to perinatal outcomes, but it could be used as baseline parameter in future toxicological studies, regarding to long-term toxic characteristics as persistent organic pollutants, its long half-lives, bioacumulative, and expected to impose serious health effects on humans. |
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Contamination index. A novel parameter for metal and pesticide analyses in maternal blood and umbilical cordContaminationMetalsPesticidesPregnancyPURPOSE: To evaluate the contamination index of metals and pesticides in pregnant women, and to relate this to perinatal outcomes. METHODS: Descriptive, retrospective, exploratory study, developed from existing secondary data analyses at Level III maternity center. A total of 40 mothers with their newborns (NB), living in a rural area in Botucatu-Brazil and surrounding region. Blood samples from mothers and newborn were collected to determine the total contamination index for metals and pesticides. The concentrations of each metal and each pesticide were determined in blood samples of mothers and their newborns by Rudge’s results. After obtaining these concentrations, the total contamination index in mother and NB was calculated, along with its correlation with clinical parameters of NB. RESULTS: There was no correlation (p> 0.05) between maternal contamination index with NB clinical parameters, and NB contamination index versus NB clinical parameters. CONCLUSION: The maternal contamination index of metals and pesticides was not related to perinatal outcomes, but it could be used as baseline parameter in future toxicological studies, regarding to long-term toxic characteristics as persistent organic pollutants, its long half-lives, bioacumulative, and expected to impose serious health effects on humans.Laboratory of Experimental Research on Gynecology and Obstetrics and Gynecology Obstetrics and Mastology Graduate Course Botucatu Medical School Universidade Estadual Paulista (UNESP)Laboratory of General Physiology and Reproductive Toxicology Institute of Biological and Health Sciences University Center of Araguaia Universidade Federal do Mato Grosso (UFMT)Laboratory of Experimental Research on Gynecology and Obstetrics Botucatu Medical School UNESPLaboratory of Experimental Research on Gynecology and Gynecology Obstetrics and Mastology Graduate Course Botucatu Medical School UNESPGynecology Obstetrics and Mastology Graduate Course Botucatu Medical School UNESPDepartment of Morphology Institute of Biosciences UNESPDepartment of Community Medicine Faculty of Health Sciences The Arctic University of NorwayLaboratory of Experimental Research on Gynecology and Obstetrics and Gynecology Obstetrics and Mastology Graduate Course Botucatu Medical School Universidade Estadual Paulista (UNESP)Laboratory of Experimental Research on Gynecology and Obstetrics Botucatu Medical School UNESPLaboratory of Experimental Research on Gynecology and Gynecology Obstetrics and Mastology Graduate Course Botucatu Medical School UNESPGynecology Obstetrics and Mastology Graduate Course Botucatu Medical School UNESPDepartment of Morphology Institute of Biosciences UNESPUniversidade Estadual Paulista (Unesp)Universidade Federal do Mato Grosso (UFMT)The Arctic University of NorwayMotta, Ilse Sodré [UNESP]Volpato, Gustavo TadeuDamasceno, Débora Cristina [UNESP]Sinzato, Yuri Karen [UNESP]Vesentini, Giovana [UNESP]Rudge, Cibele Vieira Cunha [UNESP]Calderon, Iracema Mattos Paranhos [UNESP]Kempinas, Wilma de Grava [UNESP]Odland, Jon ØvidRudge, Marilza Vieira Cunha [UNESP]2018-12-11T17:04:36Z2018-12-11T17:04:36Z2016-07-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article490-497application/pdfhttp://dx.doi.org/10.1590/S0102-865020160070000010Acta Cirurgica Brasileira, v. 31, n. 7, p. 490-497, 2016.1678-26740102-8650http://hdl.handle.net/11449/17331110.1590/S0102-865020160070000010S0102-865020160007004902-s2.0-84979779423S0102-86502016000700490.pdf6758680388835078Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengActa Cirurgica Brasileira0,395info:eu-repo/semantics/openAccess2023-10-13T06:06:48Zoai:repositorio.unesp.br:11449/173311Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-10-13T06:06:48Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Contamination index. A novel parameter for metal and pesticide analyses in maternal blood and umbilical cord |
title |
Contamination index. A novel parameter for metal and pesticide analyses in maternal blood and umbilical cord |
spellingShingle |
Contamination index. A novel parameter for metal and pesticide analyses in maternal blood and umbilical cord Motta, Ilse Sodré [UNESP] Contamination Metals Pesticides Pregnancy |
title_short |
Contamination index. A novel parameter for metal and pesticide analyses in maternal blood and umbilical cord |
title_full |
Contamination index. A novel parameter for metal and pesticide analyses in maternal blood and umbilical cord |
title_fullStr |
Contamination index. A novel parameter for metal and pesticide analyses in maternal blood and umbilical cord |
title_full_unstemmed |
Contamination index. A novel parameter for metal and pesticide analyses in maternal blood and umbilical cord |
title_sort |
Contamination index. A novel parameter for metal and pesticide analyses in maternal blood and umbilical cord |
author |
Motta, Ilse Sodré [UNESP] |
author_facet |
Motta, Ilse Sodré [UNESP] Volpato, Gustavo Tadeu Damasceno, Débora Cristina [UNESP] Sinzato, Yuri Karen [UNESP] Vesentini, Giovana [UNESP] Rudge, Cibele Vieira Cunha [UNESP] Calderon, Iracema Mattos Paranhos [UNESP] Kempinas, Wilma de Grava [UNESP] Odland, Jon Øvid Rudge, Marilza Vieira Cunha [UNESP] |
author_role |
author |
author2 |
Volpato, Gustavo Tadeu Damasceno, Débora Cristina [UNESP] Sinzato, Yuri Karen [UNESP] Vesentini, Giovana [UNESP] Rudge, Cibele Vieira Cunha [UNESP] Calderon, Iracema Mattos Paranhos [UNESP] Kempinas, Wilma de Grava [UNESP] Odland, Jon Øvid Rudge, Marilza Vieira Cunha [UNESP] |
author2_role |
author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Universidade Federal do Mato Grosso (UFMT) The Arctic University of Norway |
dc.contributor.author.fl_str_mv |
Motta, Ilse Sodré [UNESP] Volpato, Gustavo Tadeu Damasceno, Débora Cristina [UNESP] Sinzato, Yuri Karen [UNESP] Vesentini, Giovana [UNESP] Rudge, Cibele Vieira Cunha [UNESP] Calderon, Iracema Mattos Paranhos [UNESP] Kempinas, Wilma de Grava [UNESP] Odland, Jon Øvid Rudge, Marilza Vieira Cunha [UNESP] |
dc.subject.por.fl_str_mv |
Contamination Metals Pesticides Pregnancy |
topic |
Contamination Metals Pesticides Pregnancy |
description |
PURPOSE: To evaluate the contamination index of metals and pesticides in pregnant women, and to relate this to perinatal outcomes. METHODS: Descriptive, retrospective, exploratory study, developed from existing secondary data analyses at Level III maternity center. A total of 40 mothers with their newborns (NB), living in a rural area in Botucatu-Brazil and surrounding region. Blood samples from mothers and newborn were collected to determine the total contamination index for metals and pesticides. The concentrations of each metal and each pesticide were determined in blood samples of mothers and their newborns by Rudge’s results. After obtaining these concentrations, the total contamination index in mother and NB was calculated, along with its correlation with clinical parameters of NB. RESULTS: There was no correlation (p> 0.05) between maternal contamination index with NB clinical parameters, and NB contamination index versus NB clinical parameters. CONCLUSION: The maternal contamination index of metals and pesticides was not related to perinatal outcomes, but it could be used as baseline parameter in future toxicological studies, regarding to long-term toxic characteristics as persistent organic pollutants, its long half-lives, bioacumulative, and expected to impose serious health effects on humans. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-07-01 2018-12-11T17:04:36Z 2018-12-11T17:04:36Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S0102-865020160070000010 Acta Cirurgica Brasileira, v. 31, n. 7, p. 490-497, 2016. 1678-2674 0102-8650 http://hdl.handle.net/11449/173311 10.1590/S0102-865020160070000010 S0102-86502016000700490 2-s2.0-84979779423 S0102-86502016000700490.pdf 6758680388835078 |
url |
http://dx.doi.org/10.1590/S0102-865020160070000010 http://hdl.handle.net/11449/173311 |
identifier_str_mv |
Acta Cirurgica Brasileira, v. 31, n. 7, p. 490-497, 2016. 1678-2674 0102-8650 10.1590/S0102-865020160070000010 S0102-86502016000700490 2-s2.0-84979779423 S0102-86502016000700490.pdf 6758680388835078 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Acta Cirurgica Brasileira 0,395 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
490-497 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1799964544938803200 |