Treatment of fibrinolytic alveolitis with rifamycin B diethylamide associated with gelfoam: a histological study.
Autor(a) principal: | |
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Data de Publicação: | 1997 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://www.forp.usp.br/bdj/t0181.html http://hdl.handle.net/11449/65318 |
Resumo: | The most common complication in the healing of extraction wounds is fibrinolytic alveolitis, which may also be termed dry socket. Reduction in the incidence of this condition after the application of topical antibiotics and the use of systemic antibiotics has been reported. A histological study of disturbed alveolar socket healing in rats was carried out to analyze the influence of application of rifamycin B diethylamide (Rifocin M) associated or not with Gelfoam. Sixty-four male rats (Rattus norvegicus albinus, Wistar), weighing 120-150 g, were divided into 4 groups of 16 animals each. In the second group of rats which received implants of Gelfoam, there was an intense resorption of bone walls in the initial stage. The rats that received implants of Gelfoam saturated with Rifocin M (fourth group) showed better results than the second group. The third group (only irrigation with rifamycin) showed better bone formation in the alveolar socket compared to the first, second and fourth groups. Thus, these results showed that rifamycin irrigation is useful in the control of alveolar infections. |
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Repositório Institucional da UNESP |
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spelling |
Treatment of fibrinolytic alveolitis with rifamycin B diethylamide associated with gelfoam: a histological study.gelatin spongerifamiderifamycincomparative studydrug combinationdrug effectdrug screeningpathologyrattimetooth extractiontooth paintopical drug administrationWistar ratwound healingAdministration, TopicalDrug Evaluation, PreclinicalDrug Therapy, CombinationDry SocketGelatin Sponge, AbsorbableRifamycinsTime FactorsTooth ExtractionWound HealingThe most common complication in the healing of extraction wounds is fibrinolytic alveolitis, which may also be termed dry socket. Reduction in the incidence of this condition after the application of topical antibiotics and the use of systemic antibiotics has been reported. A histological study of disturbed alveolar socket healing in rats was carried out to analyze the influence of application of rifamycin B diethylamide (Rifocin M) associated or not with Gelfoam. Sixty-four male rats (Rattus norvegicus albinus, Wistar), weighing 120-150 g, were divided into 4 groups of 16 animals each. In the second group of rats which received implants of Gelfoam, there was an intense resorption of bone walls in the initial stage. The rats that received implants of Gelfoam saturated with Rifocin M (fourth group) showed better results than the second group. The third group (only irrigation with rifamycin) showed better bone formation in the alveolar socket compared to the first, second and fourth groups. Thus, these results showed that rifamycin irrigation is useful in the control of alveolar infections.Universidade Estadual Paulista (Unesp)Carvalho, Paulo Sérgio Perri [UNESP]Mariano, Ronaldo Célio [UNESP]Okamoto, Tetuo [UNESP]2014-05-27T11:18:19Z2014-05-27T11:18:19Z1997-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article3-8http://www.forp.usp.br/bdj/t0181.htmlBrazilian dental journal, v. 8, n. 1, p. 3-8, 1997.0103-6440http://hdl.handle.net/11449/653182-s2.0-00312967880169955363968097Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBrazilian Dental Journal0,476info:eu-repo/semantics/openAccess2021-10-23T11:03:13Zoai:repositorio.unesp.br:11449/65318Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-23T11:03:13Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Treatment of fibrinolytic alveolitis with rifamycin B diethylamide associated with gelfoam: a histological study. |
title |
Treatment of fibrinolytic alveolitis with rifamycin B diethylamide associated with gelfoam: a histological study. |
spellingShingle |
Treatment of fibrinolytic alveolitis with rifamycin B diethylamide associated with gelfoam: a histological study. Carvalho, Paulo Sérgio Perri [UNESP] gelatin sponge rifamide rifamycin comparative study drug combination drug effect drug screening pathology rat time tooth extraction tooth pain topical drug administration Wistar rat wound healing Administration, Topical Drug Evaluation, Preclinical Drug Therapy, Combination Dry Socket Gelatin Sponge, Absorbable Rifamycins Time Factors Tooth Extraction Wound Healing |
title_short |
Treatment of fibrinolytic alveolitis with rifamycin B diethylamide associated with gelfoam: a histological study. |
title_full |
Treatment of fibrinolytic alveolitis with rifamycin B diethylamide associated with gelfoam: a histological study. |
title_fullStr |
Treatment of fibrinolytic alveolitis with rifamycin B diethylamide associated with gelfoam: a histological study. |
title_full_unstemmed |
Treatment of fibrinolytic alveolitis with rifamycin B diethylamide associated with gelfoam: a histological study. |
title_sort |
Treatment of fibrinolytic alveolitis with rifamycin B diethylamide associated with gelfoam: a histological study. |
author |
Carvalho, Paulo Sérgio Perri [UNESP] |
author_facet |
Carvalho, Paulo Sérgio Perri [UNESP] Mariano, Ronaldo Célio [UNESP] Okamoto, Tetuo [UNESP] |
author_role |
author |
author2 |
Mariano, Ronaldo Célio [UNESP] Okamoto, Tetuo [UNESP] |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Carvalho, Paulo Sérgio Perri [UNESP] Mariano, Ronaldo Célio [UNESP] Okamoto, Tetuo [UNESP] |
dc.subject.por.fl_str_mv |
gelatin sponge rifamide rifamycin comparative study drug combination drug effect drug screening pathology rat time tooth extraction tooth pain topical drug administration Wistar rat wound healing Administration, Topical Drug Evaluation, Preclinical Drug Therapy, Combination Dry Socket Gelatin Sponge, Absorbable Rifamycins Time Factors Tooth Extraction Wound Healing |
topic |
gelatin sponge rifamide rifamycin comparative study drug combination drug effect drug screening pathology rat time tooth extraction tooth pain topical drug administration Wistar rat wound healing Administration, Topical Drug Evaluation, Preclinical Drug Therapy, Combination Dry Socket Gelatin Sponge, Absorbable Rifamycins Time Factors Tooth Extraction Wound Healing |
description |
The most common complication in the healing of extraction wounds is fibrinolytic alveolitis, which may also be termed dry socket. Reduction in the incidence of this condition after the application of topical antibiotics and the use of systemic antibiotics has been reported. A histological study of disturbed alveolar socket healing in rats was carried out to analyze the influence of application of rifamycin B diethylamide (Rifocin M) associated or not with Gelfoam. Sixty-four male rats (Rattus norvegicus albinus, Wistar), weighing 120-150 g, were divided into 4 groups of 16 animals each. In the second group of rats which received implants of Gelfoam, there was an intense resorption of bone walls in the initial stage. The rats that received implants of Gelfoam saturated with Rifocin M (fourth group) showed better results than the second group. The third group (only irrigation with rifamycin) showed better bone formation in the alveolar socket compared to the first, second and fourth groups. Thus, these results showed that rifamycin irrigation is useful in the control of alveolar infections. |
publishDate |
1997 |
dc.date.none.fl_str_mv |
1997-12-01 2014-05-27T11:18:19Z 2014-05-27T11:18:19Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.forp.usp.br/bdj/t0181.html Brazilian dental journal, v. 8, n. 1, p. 3-8, 1997. 0103-6440 http://hdl.handle.net/11449/65318 2-s2.0-0031296788 0169955363968097 |
url |
http://www.forp.usp.br/bdj/t0181.html http://hdl.handle.net/11449/65318 |
identifier_str_mv |
Brazilian dental journal, v. 8, n. 1, p. 3-8, 1997. 0103-6440 2-s2.0-0031296788 0169955363968097 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Brazilian Dental Journal 0,476 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
3-8 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1803649899741315072 |