Relationship of the aggregation of cardiovascular risk factors in the parasympathetic modulation of young people with type 1 diabetes
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.3390/medicina55090534 http://hdl.handle.net/11449/190633 |
Resumo: | Background and objectives: In healthy individuals, autonomic alterations are associated with the aggregation of cardiovascular risk factors. However, in individuals with type 1 diabetes, who are known to present autonomic alterations, mainly characterized by a reduction in parasympathetic modulation, these associations have not yet been investigated. We assess whether the aggregation of cardiovascular risk factors influences parasympathetic indices of heart rate variability in young people with type 1 diabetes. Materials and methods: This cross-sectional study included 39 individuals with type 1 diabetes (22.54 ± 4.31), evaluated in relation to the risk factors: blood pressure, fat percentage, and resting heart rate. For heart rate variability analysis, heart rate was recorded beat-to-beat using a cardio frequency meter (PolarS810i) for 30 min with the volunteers in dorsal decubitus. The parasympathetic heart rate variability indices were calculated: rMSSD, pNN50, high frequency (HF) n.u (normalized units), SD1, 2LV, and 2ULV. Data collection was carried out in 2014 and analyzed in 2017. Results: Individuals with two aggregate risk factors present a reduction in the values of the indices that reflect parasympathetic autonomic modulation compared to individuals without the risk factors analyzed, regardless of sex and age. Conclusion: In young people with type 1 diabetes, the aggregation of cardiovascular risk factors is associated with parasympathetic autonomic impairment. |
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Relationship of the aggregation of cardiovascular risk factors in the parasympathetic modulation of young people with type 1 diabetesAutonomic nervous systemDiabetes mellitusRisk factorsType 1Young adultBackground and objectives: In healthy individuals, autonomic alterations are associated with the aggregation of cardiovascular risk factors. However, in individuals with type 1 diabetes, who are known to present autonomic alterations, mainly characterized by a reduction in parasympathetic modulation, these associations have not yet been investigated. We assess whether the aggregation of cardiovascular risk factors influences parasympathetic indices of heart rate variability in young people with type 1 diabetes. Materials and methods: This cross-sectional study included 39 individuals with type 1 diabetes (22.54 ± 4.31), evaluated in relation to the risk factors: blood pressure, fat percentage, and resting heart rate. For heart rate variability analysis, heart rate was recorded beat-to-beat using a cardio frequency meter (PolarS810i) for 30 min with the volunteers in dorsal decubitus. The parasympathetic heart rate variability indices were calculated: rMSSD, pNN50, high frequency (HF) n.u (normalized units), SD1, 2LV, and 2ULV. Data collection was carried out in 2014 and analyzed in 2017. Results: Individuals with two aggregate risk factors present a reduction in the values of the indices that reflect parasympathetic autonomic modulation compared to individuals without the risk factors analyzed, regardless of sex and age. Conclusion: In young people with type 1 diabetes, the aggregation of cardiovascular risk factors is associated with parasympathetic autonomic impairment.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Department of Physical Therapy Faculty of Science and Technology São Paulo State University (UNESP), Roberto Simonsen Street, 305Department of Physical Therapy Faculty of Science and Technology São Paulo State University (UNESP), Roberto Simonsen Street, 305FAPESP: 2013/19055-0Universidade Estadual Paulista (Unesp)da Silva, Anne Kastelianne França [UNESP]Christofaro, Diego Giulliano Destro [UNESP]Vanzella, Laís Manata [UNESP]Vanderlei, Franciele Marques [UNESP]Laurino, Maria Júlia Lopez [UNESP]Vanderlei, Luiz Carlos Marques [UNESP]2019-10-06T17:19:40Z2019-10-06T17:19:40Z2019-09-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.3390/medicina55090534Medicina (Lithuania), v. 55, n. 9, 2019.1010-660Xhttp://hdl.handle.net/11449/19063310.3390/medicina550905342-s2.0-850718582765860525135106995Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengMedicina (Lithuania)info:eu-repo/semantics/openAccess2024-06-18T18:43:33Zoai:repositorio.unesp.br:11449/190633Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T15:16:25.131870Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Relationship of the aggregation of cardiovascular risk factors in the parasympathetic modulation of young people with type 1 diabetes |
title |
Relationship of the aggregation of cardiovascular risk factors in the parasympathetic modulation of young people with type 1 diabetes |
spellingShingle |
Relationship of the aggregation of cardiovascular risk factors in the parasympathetic modulation of young people with type 1 diabetes da Silva, Anne Kastelianne França [UNESP] Autonomic nervous system Diabetes mellitus Risk factors Type 1 Young adult |
title_short |
Relationship of the aggregation of cardiovascular risk factors in the parasympathetic modulation of young people with type 1 diabetes |
title_full |
Relationship of the aggregation of cardiovascular risk factors in the parasympathetic modulation of young people with type 1 diabetes |
title_fullStr |
Relationship of the aggregation of cardiovascular risk factors in the parasympathetic modulation of young people with type 1 diabetes |
title_full_unstemmed |
Relationship of the aggregation of cardiovascular risk factors in the parasympathetic modulation of young people with type 1 diabetes |
title_sort |
Relationship of the aggregation of cardiovascular risk factors in the parasympathetic modulation of young people with type 1 diabetes |
author |
da Silva, Anne Kastelianne França [UNESP] |
author_facet |
da Silva, Anne Kastelianne França [UNESP] Christofaro, Diego Giulliano Destro [UNESP] Vanzella, Laís Manata [UNESP] Vanderlei, Franciele Marques [UNESP] Laurino, Maria Júlia Lopez [UNESP] Vanderlei, Luiz Carlos Marques [UNESP] |
author_role |
author |
author2 |
Christofaro, Diego Giulliano Destro [UNESP] Vanzella, Laís Manata [UNESP] Vanderlei, Franciele Marques [UNESP] Laurino, Maria Júlia Lopez [UNESP] Vanderlei, Luiz Carlos Marques [UNESP] |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
da Silva, Anne Kastelianne França [UNESP] Christofaro, Diego Giulliano Destro [UNESP] Vanzella, Laís Manata [UNESP] Vanderlei, Franciele Marques [UNESP] Laurino, Maria Júlia Lopez [UNESP] Vanderlei, Luiz Carlos Marques [UNESP] |
dc.subject.por.fl_str_mv |
Autonomic nervous system Diabetes mellitus Risk factors Type 1 Young adult |
topic |
Autonomic nervous system Diabetes mellitus Risk factors Type 1 Young adult |
description |
Background and objectives: In healthy individuals, autonomic alterations are associated with the aggregation of cardiovascular risk factors. However, in individuals with type 1 diabetes, who are known to present autonomic alterations, mainly characterized by a reduction in parasympathetic modulation, these associations have not yet been investigated. We assess whether the aggregation of cardiovascular risk factors influences parasympathetic indices of heart rate variability in young people with type 1 diabetes. Materials and methods: This cross-sectional study included 39 individuals with type 1 diabetes (22.54 ± 4.31), evaluated in relation to the risk factors: blood pressure, fat percentage, and resting heart rate. For heart rate variability analysis, heart rate was recorded beat-to-beat using a cardio frequency meter (PolarS810i) for 30 min with the volunteers in dorsal decubitus. The parasympathetic heart rate variability indices were calculated: rMSSD, pNN50, high frequency (HF) n.u (normalized units), SD1, 2LV, and 2ULV. Data collection was carried out in 2014 and analyzed in 2017. Results: Individuals with two aggregate risk factors present a reduction in the values of the indices that reflect parasympathetic autonomic modulation compared to individuals without the risk factors analyzed, regardless of sex and age. Conclusion: In young people with type 1 diabetes, the aggregation of cardiovascular risk factors is associated with parasympathetic autonomic impairment. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-10-06T17:19:40Z 2019-10-06T17:19:40Z 2019-09-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.3390/medicina55090534 Medicina (Lithuania), v. 55, n. 9, 2019. 1010-660X http://hdl.handle.net/11449/190633 10.3390/medicina55090534 2-s2.0-85071858276 5860525135106995 |
url |
http://dx.doi.org/10.3390/medicina55090534 http://hdl.handle.net/11449/190633 |
identifier_str_mv |
Medicina (Lithuania), v. 55, n. 9, 2019. 1010-660X 10.3390/medicina55090534 2-s2.0-85071858276 5860525135106995 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Medicina (Lithuania) |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128491781095424 |