Effects of acute normovolemic anemia on hemodynamic parameters and acid-base balance in dogs

Detalhes bibliográficos
Autor(a) principal: Champion, Tatiana [UNESP]
Data de Publicação: 2011
Outros Autores: Pereira Neto, Glaucia Bueno [UNESP], Camacho, Aparecido Antonio [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.4061/2011/829054
http://hdl.handle.net/11449/72917
Resumo: The aim of this study was to evaluate the hemodynamic and acid-base status of dogs subjected to acute normovolemic anemia. The dogs (n = 10) were evaluated 15 minutes and 24 hours after induction of anemia (hematocrit below 18) with blood withdrawal and simultaneously replacement of same volume of Ringer's lactate solution and hydroxyethyl starch-based solution in a 2:1 ratio. The cardiac output was measured by Doppler echocardiography and blood pressure by oscillometric device, and posteriorly hemodynamic parameters were calculated. The anemic groups had increase in cardiac index (P <.05) (3.82 ± 1.05 to 5.86 ± 1.49 and 5.81 ± 1.63 L/min m) and decreases (P <.05) in the indices of total peripheral resistance (6797.81 ± 3060.22 to 3220.14 ± 1275.02 and 3887.74 ± 1394.89 dinaseg/cm 5× m2) and oxygen delivery (7942.84 ± 3344.00 to 4021.68 ± 1627.00 and 4430.82 ± 1402.61 mL/min× m 2), respectively. There were no significant changes in pH, but PaO2 and SaO2 values were increased, and PaCO2 reduced in anemic dogs (P <.05). Therefore, acute normovolemic anemia can create significant hemodynamic changes and despite some hemogasometric changes, there were no changes in the acid-base status in dogs. Copyright © 2011 Tatiana Champion et al.
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spelling Effects of acute normovolemic anemia on hemodynamic parameters and acid-base balance in dogsCanis familiarisThe aim of this study was to evaluate the hemodynamic and acid-base status of dogs subjected to acute normovolemic anemia. The dogs (n = 10) were evaluated 15 minutes and 24 hours after induction of anemia (hematocrit below 18) with blood withdrawal and simultaneously replacement of same volume of Ringer's lactate solution and hydroxyethyl starch-based solution in a 2:1 ratio. The cardiac output was measured by Doppler echocardiography and blood pressure by oscillometric device, and posteriorly hemodynamic parameters were calculated. The anemic groups had increase in cardiac index (P <.05) (3.82 ± 1.05 to 5.86 ± 1.49 and 5.81 ± 1.63 L/min m) and decreases (P <.05) in the indices of total peripheral resistance (6797.81 ± 3060.22 to 3220.14 ± 1275.02 and 3887.74 ± 1394.89 dinaseg/cm 5× m2) and oxygen delivery (7942.84 ± 3344.00 to 4021.68 ± 1627.00 and 4430.82 ± 1402.61 mL/min× m 2), respectively. There were no significant changes in pH, but PaO2 and SaO2 values were increased, and PaCO2 reduced in anemic dogs (P <.05). Therefore, acute normovolemic anemia can create significant hemodynamic changes and despite some hemogasometric changes, there were no changes in the acid-base status in dogs. Copyright © 2011 Tatiana Champion et al.Department of Animal Surgery and Clinical Sciences Faculty of Agricultural and Veterinary Sciences (FCAV) S̃ao Paulo State University (UNESP), Via de Acesso Professor Paulo Donato Castellane, km 5, 14884-900 Jaboticabal, SPDepartment of Animal Surgery and Clinical Sciences Faculty of Agricultural and Veterinary Sciences (FCAV) S̃ao Paulo State University (UNESP), Via de Acesso Professor Paulo Donato Castellane, km 5, 14884-900 Jaboticabal, SPUniversidade Estadual Paulista (Unesp)Champion, Tatiana [UNESP]Pereira Neto, Glaucia Bueno [UNESP]Camacho, Aparecido Antonio [UNESP]2014-05-27T11:26:16Z2014-05-27T11:26:16Z2011-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://dx.doi.org/10.4061/2011/829054Veterinary Medicine International, v. 2011.2042-0048http://hdl.handle.net/11449/7291710.4061/2011/8290542-s2.0-848608599282-s2.0-84860859928.pdf9642688764978907Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengVeterinary Medicine International0,536info:eu-repo/semantics/openAccess2024-06-06T14:09:53Zoai:repositorio.unesp.br:11449/72917Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T17:11:01.093136Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Effects of acute normovolemic anemia on hemodynamic parameters and acid-base balance in dogs
title Effects of acute normovolemic anemia on hemodynamic parameters and acid-base balance in dogs
spellingShingle Effects of acute normovolemic anemia on hemodynamic parameters and acid-base balance in dogs
Champion, Tatiana [UNESP]
Canis familiaris
title_short Effects of acute normovolemic anemia on hemodynamic parameters and acid-base balance in dogs
title_full Effects of acute normovolemic anemia on hemodynamic parameters and acid-base balance in dogs
title_fullStr Effects of acute normovolemic anemia on hemodynamic parameters and acid-base balance in dogs
title_full_unstemmed Effects of acute normovolemic anemia on hemodynamic parameters and acid-base balance in dogs
title_sort Effects of acute normovolemic anemia on hemodynamic parameters and acid-base balance in dogs
author Champion, Tatiana [UNESP]
author_facet Champion, Tatiana [UNESP]
Pereira Neto, Glaucia Bueno [UNESP]
Camacho, Aparecido Antonio [UNESP]
author_role author
author2 Pereira Neto, Glaucia Bueno [UNESP]
Camacho, Aparecido Antonio [UNESP]
author2_role author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Champion, Tatiana [UNESP]
Pereira Neto, Glaucia Bueno [UNESP]
Camacho, Aparecido Antonio [UNESP]
dc.subject.por.fl_str_mv Canis familiaris
topic Canis familiaris
description The aim of this study was to evaluate the hemodynamic and acid-base status of dogs subjected to acute normovolemic anemia. The dogs (n = 10) were evaluated 15 minutes and 24 hours after induction of anemia (hematocrit below 18) with blood withdrawal and simultaneously replacement of same volume of Ringer's lactate solution and hydroxyethyl starch-based solution in a 2:1 ratio. The cardiac output was measured by Doppler echocardiography and blood pressure by oscillometric device, and posteriorly hemodynamic parameters were calculated. The anemic groups had increase in cardiac index (P <.05) (3.82 ± 1.05 to 5.86 ± 1.49 and 5.81 ± 1.63 L/min m) and decreases (P <.05) in the indices of total peripheral resistance (6797.81 ± 3060.22 to 3220.14 ± 1275.02 and 3887.74 ± 1394.89 dinaseg/cm 5× m2) and oxygen delivery (7942.84 ± 3344.00 to 4021.68 ± 1627.00 and 4430.82 ± 1402.61 mL/min× m 2), respectively. There were no significant changes in pH, but PaO2 and SaO2 values were increased, and PaCO2 reduced in anemic dogs (P <.05). Therefore, acute normovolemic anemia can create significant hemodynamic changes and despite some hemogasometric changes, there were no changes in the acid-base status in dogs. Copyright © 2011 Tatiana Champion et al.
publishDate 2011
dc.date.none.fl_str_mv 2011-12-01
2014-05-27T11:26:16Z
2014-05-27T11:26:16Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.4061/2011/829054
Veterinary Medicine International, v. 2011.
2042-0048
http://hdl.handle.net/11449/72917
10.4061/2011/829054
2-s2.0-84860859928
2-s2.0-84860859928.pdf
9642688764978907
url http://dx.doi.org/10.4061/2011/829054
http://hdl.handle.net/11449/72917
identifier_str_mv Veterinary Medicine International, v. 2011.
2042-0048
10.4061/2011/829054
2-s2.0-84860859928
2-s2.0-84860859928.pdf
9642688764978907
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Veterinary Medicine International
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dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
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dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
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