Effects of acute normovolemic anemia on hemodynamic parameters and acid-base balance in dogs
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.4061/2011/829054 http://hdl.handle.net/11449/72917 |
Resumo: | The aim of this study was to evaluate the hemodynamic and acid-base status of dogs subjected to acute normovolemic anemia. The dogs (n = 10) were evaluated 15 minutes and 24 hours after induction of anemia (hematocrit below 18) with blood withdrawal and simultaneously replacement of same volume of Ringer's lactate solution and hydroxyethyl starch-based solution in a 2:1 ratio. The cardiac output was measured by Doppler echocardiography and blood pressure by oscillometric device, and posteriorly hemodynamic parameters were calculated. The anemic groups had increase in cardiac index (P <.05) (3.82 ± 1.05 to 5.86 ± 1.49 and 5.81 ± 1.63 L/min m) and decreases (P <.05) in the indices of total peripheral resistance (6797.81 ± 3060.22 to 3220.14 ± 1275.02 and 3887.74 ± 1394.89 dinaseg/cm 5× m2) and oxygen delivery (7942.84 ± 3344.00 to 4021.68 ± 1627.00 and 4430.82 ± 1402.61 mL/min× m 2), respectively. There were no significant changes in pH, but PaO2 and SaO2 values were increased, and PaCO2 reduced in anemic dogs (P <.05). Therefore, acute normovolemic anemia can create significant hemodynamic changes and despite some hemogasometric changes, there were no changes in the acid-base status in dogs. Copyright © 2011 Tatiana Champion et al. |
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Effects of acute normovolemic anemia on hemodynamic parameters and acid-base balance in dogsCanis familiarisThe aim of this study was to evaluate the hemodynamic and acid-base status of dogs subjected to acute normovolemic anemia. The dogs (n = 10) were evaluated 15 minutes and 24 hours after induction of anemia (hematocrit below 18) with blood withdrawal and simultaneously replacement of same volume of Ringer's lactate solution and hydroxyethyl starch-based solution in a 2:1 ratio. The cardiac output was measured by Doppler echocardiography and blood pressure by oscillometric device, and posteriorly hemodynamic parameters were calculated. The anemic groups had increase in cardiac index (P <.05) (3.82 ± 1.05 to 5.86 ± 1.49 and 5.81 ± 1.63 L/min m) and decreases (P <.05) in the indices of total peripheral resistance (6797.81 ± 3060.22 to 3220.14 ± 1275.02 and 3887.74 ± 1394.89 dinaseg/cm 5× m2) and oxygen delivery (7942.84 ± 3344.00 to 4021.68 ± 1627.00 and 4430.82 ± 1402.61 mL/min× m 2), respectively. There were no significant changes in pH, but PaO2 and SaO2 values were increased, and PaCO2 reduced in anemic dogs (P <.05). Therefore, acute normovolemic anemia can create significant hemodynamic changes and despite some hemogasometric changes, there were no changes in the acid-base status in dogs. Copyright © 2011 Tatiana Champion et al.Department of Animal Surgery and Clinical Sciences Faculty of Agricultural and Veterinary Sciences (FCAV) S̃ao Paulo State University (UNESP), Via de Acesso Professor Paulo Donato Castellane, km 5, 14884-900 Jaboticabal, SPDepartment of Animal Surgery and Clinical Sciences Faculty of Agricultural and Veterinary Sciences (FCAV) S̃ao Paulo State University (UNESP), Via de Acesso Professor Paulo Donato Castellane, km 5, 14884-900 Jaboticabal, SPUniversidade Estadual Paulista (Unesp)Champion, Tatiana [UNESP]Pereira Neto, Glaucia Bueno [UNESP]Camacho, Aparecido Antonio [UNESP]2014-05-27T11:26:16Z2014-05-27T11:26:16Z2011-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://dx.doi.org/10.4061/2011/829054Veterinary Medicine International, v. 2011.2042-0048http://hdl.handle.net/11449/7291710.4061/2011/8290542-s2.0-848608599282-s2.0-84860859928.pdf9642688764978907Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengVeterinary Medicine International0,536info:eu-repo/semantics/openAccess2024-06-06T14:09:53Zoai:repositorio.unesp.br:11449/72917Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T17:11:01.093136Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Effects of acute normovolemic anemia on hemodynamic parameters and acid-base balance in dogs |
title |
Effects of acute normovolemic anemia on hemodynamic parameters and acid-base balance in dogs |
spellingShingle |
Effects of acute normovolemic anemia on hemodynamic parameters and acid-base balance in dogs Champion, Tatiana [UNESP] Canis familiaris |
title_short |
Effects of acute normovolemic anemia on hemodynamic parameters and acid-base balance in dogs |
title_full |
Effects of acute normovolemic anemia on hemodynamic parameters and acid-base balance in dogs |
title_fullStr |
Effects of acute normovolemic anemia on hemodynamic parameters and acid-base balance in dogs |
title_full_unstemmed |
Effects of acute normovolemic anemia on hemodynamic parameters and acid-base balance in dogs |
title_sort |
Effects of acute normovolemic anemia on hemodynamic parameters and acid-base balance in dogs |
author |
Champion, Tatiana [UNESP] |
author_facet |
Champion, Tatiana [UNESP] Pereira Neto, Glaucia Bueno [UNESP] Camacho, Aparecido Antonio [UNESP] |
author_role |
author |
author2 |
Pereira Neto, Glaucia Bueno [UNESP] Camacho, Aparecido Antonio [UNESP] |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Champion, Tatiana [UNESP] Pereira Neto, Glaucia Bueno [UNESP] Camacho, Aparecido Antonio [UNESP] |
dc.subject.por.fl_str_mv |
Canis familiaris |
topic |
Canis familiaris |
description |
The aim of this study was to evaluate the hemodynamic and acid-base status of dogs subjected to acute normovolemic anemia. The dogs (n = 10) were evaluated 15 minutes and 24 hours after induction of anemia (hematocrit below 18) with blood withdrawal and simultaneously replacement of same volume of Ringer's lactate solution and hydroxyethyl starch-based solution in a 2:1 ratio. The cardiac output was measured by Doppler echocardiography and blood pressure by oscillometric device, and posteriorly hemodynamic parameters were calculated. The anemic groups had increase in cardiac index (P <.05) (3.82 ± 1.05 to 5.86 ± 1.49 and 5.81 ± 1.63 L/min m) and decreases (P <.05) in the indices of total peripheral resistance (6797.81 ± 3060.22 to 3220.14 ± 1275.02 and 3887.74 ± 1394.89 dinaseg/cm 5× m2) and oxygen delivery (7942.84 ± 3344.00 to 4021.68 ± 1627.00 and 4430.82 ± 1402.61 mL/min× m 2), respectively. There were no significant changes in pH, but PaO2 and SaO2 values were increased, and PaCO2 reduced in anemic dogs (P <.05). Therefore, acute normovolemic anemia can create significant hemodynamic changes and despite some hemogasometric changes, there were no changes in the acid-base status in dogs. Copyright © 2011 Tatiana Champion et al. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-12-01 2014-05-27T11:26:16Z 2014-05-27T11:26:16Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.4061/2011/829054 Veterinary Medicine International, v. 2011. 2042-0048 http://hdl.handle.net/11449/72917 10.4061/2011/829054 2-s2.0-84860859928 2-s2.0-84860859928.pdf 9642688764978907 |
url |
http://dx.doi.org/10.4061/2011/829054 http://hdl.handle.net/11449/72917 |
identifier_str_mv |
Veterinary Medicine International, v. 2011. 2042-0048 10.4061/2011/829054 2-s2.0-84860859928 2-s2.0-84860859928.pdf 9642688764978907 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Veterinary Medicine International 0,536 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1808128768013762560 |