Cães intoxicados com folhas frescas de Nerium oleander: Achados clínicos e eletrocardiográficos
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/0103-8478cr20160970 http://hdl.handle.net/11449/169658 |
Resumo: | Nerium oleander is distributed worldwide, mainly in tropical and subtropical regions. These shrubs are frequently used as ornamental plants. However, they contain more than 30 cardiac glycosides that can cause serious toxic effects in dogs. The objective of this study was to report the clinical and electrocardiographic alterations in dogs experimentally poisoned with N. oleander. Ten adult, healthy, mixed-breed dogs weighing 10- 25kg and aged 3-6 years were selected for the study. We orally administered 0.25g kg-1 of fresh ground leaves of N. oleander to the dogs. No dog died after the ingestion, but all exhibited signs of poisoning such as vomiting, sialorrhea, nausea, apathy, conjunctiva congestion, dehydration, abdominal pain, tremors, diarrhea, loss of appetite, and tenesmus. Electrocardiogram revealed occurrence of several types of arrhythmias: sinus bradycardia, second-degree atrioventricular block, paroxysmal ventricular tachycardia, and ventricular premature complexes. Systolic blood pressure, as well as heart rate, decreased in the first 24 hours. The present study concluded that a single dose of 0.25g kg-1 of N. oleander green leaves is sufficient to cause a moderate intoxication in dogs, with nonspecific clinical changes mainly related to the digestive system and heart rate, thus demonstrating the importance of this type of intoxication in the list of differential diagnoses of small animals routine. |
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Cães intoxicados com folhas frescas de Nerium oleander: Achados clínicos e eletrocardiográficosPoisoned with Nerium oleander fresh leaves: Clinical and electrocardiographic findingsArrhythmiaBlood pressureCanineCardiac glycosidesElectrocardiographyNerium oleander is distributed worldwide, mainly in tropical and subtropical regions. These shrubs are frequently used as ornamental plants. However, they contain more than 30 cardiac glycosides that can cause serious toxic effects in dogs. The objective of this study was to report the clinical and electrocardiographic alterations in dogs experimentally poisoned with N. oleander. Ten adult, healthy, mixed-breed dogs weighing 10- 25kg and aged 3-6 years were selected for the study. We orally administered 0.25g kg-1 of fresh ground leaves of N. oleander to the dogs. No dog died after the ingestion, but all exhibited signs of poisoning such as vomiting, sialorrhea, nausea, apathy, conjunctiva congestion, dehydration, abdominal pain, tremors, diarrhea, loss of appetite, and tenesmus. Electrocardiogram revealed occurrence of several types of arrhythmias: sinus bradycardia, second-degree atrioventricular block, paroxysmal ventricular tachycardia, and ventricular premature complexes. Systolic blood pressure, as well as heart rate, decreased in the first 24 hours. The present study concluded that a single dose of 0.25g kg-1 of N. oleander green leaves is sufficient to cause a moderate intoxication in dogs, with nonspecific clinical changes mainly related to the digestive system and heart rate, thus demonstrating the importance of this type of intoxication in the list of differential diagnoses of small animals routine.Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Departamento de Clínica Médica Veterinária Univesidade Estadual Paulista ‘Júlio de Mesquita Filho’ (UNESP), Via de Acesso Prof. Paulo Donato Castellane, s/nDepartamento de Clínica Médica Veterinária Universidade Federal do Goiás (UFG)Departamento de Medicina Veterinária Universidade Estadual do Centro-Oeste (UNICENTRO)Departamento de Clínica Médica Veterinária Univesidade Estadual Paulista ‘Júlio de Mesquita Filho’ (UNESP), Via de Acesso Prof. Paulo Donato Castellane, s/nUniversidade Estadual Paulista (Unesp)Universidade Federal do Goiás (UFG)Universidade Estadual do Centro-Oeste (UNICENTRO)Camplesi, Annelise Carla [UNESP]Bellodi, Carolina [UNESP]Socha, José Javier Mesa [UNESP]Hatayde, Mário Roberto [UNESP]Sobreira, Márcia Ferreira da Rosa [UNESP]Araujo, Gustavo Henrique MarquesAraujo, Carla Fredrichsen Moya2018-12-11T16:47:03Z2018-12-11T16:47:03Z2017-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://dx.doi.org/10.1590/0103-8478cr20160970Ciencia Rural, v. 47, n. 6, 2017.1678-45960103-8478http://hdl.handle.net/11449/16965810.1590/0103-8478cr20160970S0103-847820170006005532-s2.0-85018426002S0103-84782017000600553.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengCiencia Rural0,337info:eu-repo/semantics/openAccess2023-10-14T06:05:25Zoai:repositorio.unesp.br:11449/169658Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T14:52:47.923418Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Cães intoxicados com folhas frescas de Nerium oleander: Achados clínicos e eletrocardiográficos Poisoned with Nerium oleander fresh leaves: Clinical and electrocardiographic findings |
title |
Cães intoxicados com folhas frescas de Nerium oleander: Achados clínicos e eletrocardiográficos |
spellingShingle |
Cães intoxicados com folhas frescas de Nerium oleander: Achados clínicos e eletrocardiográficos Camplesi, Annelise Carla [UNESP] Arrhythmia Blood pressure Canine Cardiac glycosides Electrocardiography |
title_short |
Cães intoxicados com folhas frescas de Nerium oleander: Achados clínicos e eletrocardiográficos |
title_full |
Cães intoxicados com folhas frescas de Nerium oleander: Achados clínicos e eletrocardiográficos |
title_fullStr |
Cães intoxicados com folhas frescas de Nerium oleander: Achados clínicos e eletrocardiográficos |
title_full_unstemmed |
Cães intoxicados com folhas frescas de Nerium oleander: Achados clínicos e eletrocardiográficos |
title_sort |
Cães intoxicados com folhas frescas de Nerium oleander: Achados clínicos e eletrocardiográficos |
author |
Camplesi, Annelise Carla [UNESP] |
author_facet |
Camplesi, Annelise Carla [UNESP] Bellodi, Carolina [UNESP] Socha, José Javier Mesa [UNESP] Hatayde, Mário Roberto [UNESP] Sobreira, Márcia Ferreira da Rosa [UNESP] Araujo, Gustavo Henrique Marques Araujo, Carla Fredrichsen Moya |
author_role |
author |
author2 |
Bellodi, Carolina [UNESP] Socha, José Javier Mesa [UNESP] Hatayde, Mário Roberto [UNESP] Sobreira, Márcia Ferreira da Rosa [UNESP] Araujo, Gustavo Henrique Marques Araujo, Carla Fredrichsen Moya |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Universidade Federal do Goiás (UFG) Universidade Estadual do Centro-Oeste (UNICENTRO) |
dc.contributor.author.fl_str_mv |
Camplesi, Annelise Carla [UNESP] Bellodi, Carolina [UNESP] Socha, José Javier Mesa [UNESP] Hatayde, Mário Roberto [UNESP] Sobreira, Márcia Ferreira da Rosa [UNESP] Araujo, Gustavo Henrique Marques Araujo, Carla Fredrichsen Moya |
dc.subject.por.fl_str_mv |
Arrhythmia Blood pressure Canine Cardiac glycosides Electrocardiography |
topic |
Arrhythmia Blood pressure Canine Cardiac glycosides Electrocardiography |
description |
Nerium oleander is distributed worldwide, mainly in tropical and subtropical regions. These shrubs are frequently used as ornamental plants. However, they contain more than 30 cardiac glycosides that can cause serious toxic effects in dogs. The objective of this study was to report the clinical and electrocardiographic alterations in dogs experimentally poisoned with N. oleander. Ten adult, healthy, mixed-breed dogs weighing 10- 25kg and aged 3-6 years were selected for the study. We orally administered 0.25g kg-1 of fresh ground leaves of N. oleander to the dogs. No dog died after the ingestion, but all exhibited signs of poisoning such as vomiting, sialorrhea, nausea, apathy, conjunctiva congestion, dehydration, abdominal pain, tremors, diarrhea, loss of appetite, and tenesmus. Electrocardiogram revealed occurrence of several types of arrhythmias: sinus bradycardia, second-degree atrioventricular block, paroxysmal ventricular tachycardia, and ventricular premature complexes. Systolic blood pressure, as well as heart rate, decreased in the first 24 hours. The present study concluded that a single dose of 0.25g kg-1 of N. oleander green leaves is sufficient to cause a moderate intoxication in dogs, with nonspecific clinical changes mainly related to the digestive system and heart rate, thus demonstrating the importance of this type of intoxication in the list of differential diagnoses of small animals routine. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-01-01 2018-12-11T16:47:03Z 2018-12-11T16:47:03Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/0103-8478cr20160970 Ciencia Rural, v. 47, n. 6, 2017. 1678-4596 0103-8478 http://hdl.handle.net/11449/169658 10.1590/0103-8478cr20160970 S0103-84782017000600553 2-s2.0-85018426002 S0103-84782017000600553.pdf |
url |
http://dx.doi.org/10.1590/0103-8478cr20160970 http://hdl.handle.net/11449/169658 |
identifier_str_mv |
Ciencia Rural, v. 47, n. 6, 2017. 1678-4596 0103-8478 10.1590/0103-8478cr20160970 S0103-84782017000600553 2-s2.0-85018426002 S0103-84782017000600553.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Ciencia Rural 0,337 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1808128429097222144 |