Metabolic and respiratory chemosensitivity and brain monoaminergic responses to cold exposure in chicks subjected to thermal manipulation during incubation: Impact of embryonic thermal manipulation on cold response
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.jtherbio.2022.103317 http://hdl.handle.net/11449/247626 |
Resumo: | We evaluated ventilation (V˙E), body temperature (TB), oxygen consumption (V˙ O2), respiratory equivalent (V˙E/ V˙ O2), and monoamine concentrations of 14-day-old (14d) male and female chicks from eggs incubated at low (LT, 36 °C), control (CT, 37.5 °C) and high (HT, 39 °C) temperature during the early embryonic phase, to normoxia, hypercapnia and hypoxia under exposure to cold environment (20 °C). At normoxia, acute cold exposure did not affect the ventilatory variables, with the exception of HT males, in which cold prevented the reduced V˙E observed under thermoneutral conditions. Exposure to 20 °C caused a decrease in TB in both sexes, and LT and HT females presented a greater hypothermic response. Hypercapnia combined with cold did not alter the ventilatory variables, but LT females and CT males and females showed a blunted CO2-induced hyperventilation due to a higher V˙ O2, compared to the same groups in thermoneutral conditions. Unlike with thermoneutral conditions, the blunted hypercapnic hyperventilation observed in the HT groups was not observed during cold challenge. CO2 exposure promoted a similar decrease in TB in the thermoneutral and acutely cold exposed groups, while LT females under cold condition presented a blunted hypothermic response. During hypoxia, cold challenge attenuated the increase in V˙E in LT females and HT males, due to changes in VT. Hypoxic metabolic depression was greater in LT females and males and HT males during cold exposure, while no change in V˙E/ V˙ O2 was observed. The only alteration in monoaminergic concentration under cold challenge was an increase in brainstem 5-HIAA and 5-HIAA/5-HT ratio in HT females, and an enhanced 5-HT concentration in HT males. In summary, thermal manipulation during embryogenesis induces 14d old chicks to respond differently to cold stress with LT females and HT males being more sensitive. |
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Metabolic and respiratory chemosensitivity and brain monoaminergic responses to cold exposure in chicks subjected to thermal manipulation during incubation: Impact of embryonic thermal manipulation on cold responseBody temperatureBroilerHypercapniaHypoxiaIncubationVentilationWe evaluated ventilation (V˙E), body temperature (TB), oxygen consumption (V˙ O2), respiratory equivalent (V˙E/ V˙ O2), and monoamine concentrations of 14-day-old (14d) male and female chicks from eggs incubated at low (LT, 36 °C), control (CT, 37.5 °C) and high (HT, 39 °C) temperature during the early embryonic phase, to normoxia, hypercapnia and hypoxia under exposure to cold environment (20 °C). At normoxia, acute cold exposure did not affect the ventilatory variables, with the exception of HT males, in which cold prevented the reduced V˙E observed under thermoneutral conditions. Exposure to 20 °C caused a decrease in TB in both sexes, and LT and HT females presented a greater hypothermic response. Hypercapnia combined with cold did not alter the ventilatory variables, but LT females and CT males and females showed a blunted CO2-induced hyperventilation due to a higher V˙ O2, compared to the same groups in thermoneutral conditions. Unlike with thermoneutral conditions, the blunted hypercapnic hyperventilation observed in the HT groups was not observed during cold challenge. CO2 exposure promoted a similar decrease in TB in the thermoneutral and acutely cold exposed groups, while LT females under cold condition presented a blunted hypothermic response. During hypoxia, cold challenge attenuated the increase in V˙E in LT females and HT males, due to changes in VT. Hypoxic metabolic depression was greater in LT females and males and HT males during cold exposure, while no change in V˙E/ V˙ O2 was observed. The only alteration in monoaminergic concentration under cold challenge was an increase in brainstem 5-HIAA and 5-HIAA/5-HT ratio in HT females, and an enhanced 5-HT concentration in HT males. In summary, thermal manipulation during embryogenesis induces 14d old chicks to respond differently to cold stress with LT females and HT males being more sensitive.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Department of Animal Morphology and Physiology College of Agricultural and Veterinarian Sciences São Paulo State University, JaboticabalDepartment of Physiology and Biophysics Institute of Biological Sciences Federal University of Minas Gerais – UFMG, MGDepartment of Animal Morphology and Physiology College of Agricultural and Veterinarian Sciences São Paulo State University, JaboticabalCAPES: 001FAPESP: 2019/09469-8FAPESP: 2019/14646-6FAPESP: 2020/01702-2CNPq: 303802/2018-9CNPq: 308249/2019-4CNPq: 407490/2018-3CAPES: 88881.310743/2018-01CAPES: 88887.194785/2018-00Universidade Estadual Paulista (UNESP)Universidade Federal de Minas Gerais (UFMG)Rocha, Aline C.G. [UNESP]Patrone, Luis Gustavo A. [UNESP]Cristina-Silva, Caroline [UNESP]Silva, Kaoma Stephani da CostaBícego, Kênia C. [UNESP]Szawka, Raphael E.Gargaglioni, Luciane H. [UNESP]2023-07-29T13:21:21Z2023-07-29T13:21:21Z2022-10-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1016/j.jtherbio.2022.103317Journal of Thermal Biology, v. 109.1879-09920306-4565http://hdl.handle.net/11449/24762610.1016/j.jtherbio.2022.1033172-s2.0-85138162580Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Thermal Biologyinfo:eu-repo/semantics/openAccess2024-06-06T18:41:55Zoai:repositorio.unesp.br:11449/247626Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T19:51:12.827939Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Metabolic and respiratory chemosensitivity and brain monoaminergic responses to cold exposure in chicks subjected to thermal manipulation during incubation: Impact of embryonic thermal manipulation on cold response |
title |
Metabolic and respiratory chemosensitivity and brain monoaminergic responses to cold exposure in chicks subjected to thermal manipulation during incubation: Impact of embryonic thermal manipulation on cold response |
spellingShingle |
Metabolic and respiratory chemosensitivity and brain monoaminergic responses to cold exposure in chicks subjected to thermal manipulation during incubation: Impact of embryonic thermal manipulation on cold response Rocha, Aline C.G. [UNESP] Body temperature Broiler Hypercapnia Hypoxia Incubation Ventilation |
title_short |
Metabolic and respiratory chemosensitivity and brain monoaminergic responses to cold exposure in chicks subjected to thermal manipulation during incubation: Impact of embryonic thermal manipulation on cold response |
title_full |
Metabolic and respiratory chemosensitivity and brain monoaminergic responses to cold exposure in chicks subjected to thermal manipulation during incubation: Impact of embryonic thermal manipulation on cold response |
title_fullStr |
Metabolic and respiratory chemosensitivity and brain monoaminergic responses to cold exposure in chicks subjected to thermal manipulation during incubation: Impact of embryonic thermal manipulation on cold response |
title_full_unstemmed |
Metabolic and respiratory chemosensitivity and brain monoaminergic responses to cold exposure in chicks subjected to thermal manipulation during incubation: Impact of embryonic thermal manipulation on cold response |
title_sort |
Metabolic and respiratory chemosensitivity and brain monoaminergic responses to cold exposure in chicks subjected to thermal manipulation during incubation: Impact of embryonic thermal manipulation on cold response |
author |
Rocha, Aline C.G. [UNESP] |
author_facet |
Rocha, Aline C.G. [UNESP] Patrone, Luis Gustavo A. [UNESP] Cristina-Silva, Caroline [UNESP] Silva, Kaoma Stephani da Costa Bícego, Kênia C. [UNESP] Szawka, Raphael E. Gargaglioni, Luciane H. [UNESP] |
author_role |
author |
author2 |
Patrone, Luis Gustavo A. [UNESP] Cristina-Silva, Caroline [UNESP] Silva, Kaoma Stephani da Costa Bícego, Kênia C. [UNESP] Szawka, Raphael E. Gargaglioni, Luciane H. [UNESP] |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) Universidade Federal de Minas Gerais (UFMG) |
dc.contributor.author.fl_str_mv |
Rocha, Aline C.G. [UNESP] Patrone, Luis Gustavo A. [UNESP] Cristina-Silva, Caroline [UNESP] Silva, Kaoma Stephani da Costa Bícego, Kênia C. [UNESP] Szawka, Raphael E. Gargaglioni, Luciane H. [UNESP] |
dc.subject.por.fl_str_mv |
Body temperature Broiler Hypercapnia Hypoxia Incubation Ventilation |
topic |
Body temperature Broiler Hypercapnia Hypoxia Incubation Ventilation |
description |
We evaluated ventilation (V˙E), body temperature (TB), oxygen consumption (V˙ O2), respiratory equivalent (V˙E/ V˙ O2), and monoamine concentrations of 14-day-old (14d) male and female chicks from eggs incubated at low (LT, 36 °C), control (CT, 37.5 °C) and high (HT, 39 °C) temperature during the early embryonic phase, to normoxia, hypercapnia and hypoxia under exposure to cold environment (20 °C). At normoxia, acute cold exposure did not affect the ventilatory variables, with the exception of HT males, in which cold prevented the reduced V˙E observed under thermoneutral conditions. Exposure to 20 °C caused a decrease in TB in both sexes, and LT and HT females presented a greater hypothermic response. Hypercapnia combined with cold did not alter the ventilatory variables, but LT females and CT males and females showed a blunted CO2-induced hyperventilation due to a higher V˙ O2, compared to the same groups in thermoneutral conditions. Unlike with thermoneutral conditions, the blunted hypercapnic hyperventilation observed in the HT groups was not observed during cold challenge. CO2 exposure promoted a similar decrease in TB in the thermoneutral and acutely cold exposed groups, while LT females under cold condition presented a blunted hypothermic response. During hypoxia, cold challenge attenuated the increase in V˙E in LT females and HT males, due to changes in VT. Hypoxic metabolic depression was greater in LT females and males and HT males during cold exposure, while no change in V˙E/ V˙ O2 was observed. The only alteration in monoaminergic concentration under cold challenge was an increase in brainstem 5-HIAA and 5-HIAA/5-HT ratio in HT females, and an enhanced 5-HT concentration in HT males. In summary, thermal manipulation during embryogenesis induces 14d old chicks to respond differently to cold stress with LT females and HT males being more sensitive. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-10-01 2023-07-29T13:21:21Z 2023-07-29T13:21:21Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.jtherbio.2022.103317 Journal of Thermal Biology, v. 109. 1879-0992 0306-4565 http://hdl.handle.net/11449/247626 10.1016/j.jtherbio.2022.103317 2-s2.0-85138162580 |
url |
http://dx.doi.org/10.1016/j.jtherbio.2022.103317 http://hdl.handle.net/11449/247626 |
identifier_str_mv |
Journal of Thermal Biology, v. 109. 1879-0992 0306-4565 10.1016/j.jtherbio.2022.103317 2-s2.0-85138162580 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Thermal Biology |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129129317400576 |