Supported core-shell nanobiosensors for quantitative fluorescence imaging of extracellular pH
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://pubs.rsc.org/en/Content/ArticleLanding/2014/CC/C4CC06075J#!divAbstract http://hdl.handle.net/11449/123552 |
Resumo: | Covalent “click” cycloaddition was used to functionalize silica substrates with pH-sensitive nanoparticles, thus producing uniform and highly luminescent analytical devices usable in both commercial fluorimeters and fluorescence microscopes. Quantitative and spatially-resolved extracellular pH measurements were successfully achieved on live cardiac fibroblasts with these novel ion-sensitive surfaces. |
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Repositório Institucional da UNESP |
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2946 |
spelling |
Supported core-shell nanobiosensors for quantitative fluorescence imaging of extracellular pHCovalent “click” cycloaddition was used to functionalize silica substrates with pH-sensitive nanoparticles, thus producing uniform and highly luminescent analytical devices usable in both commercial fluorimeters and fluorescence microscopes. Quantitative and spatially-resolved extracellular pH measurements were successfully achieved on live cardiac fibroblasts with these novel ion-sensitive surfaces.Universidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Química Geral e Inorgânica, Instituto de Química de Araraquara, Araraquara, R. Professor Francisco Degni, S/N, Quitandinha, CEP 14800-900, SP, BrasilUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Química Geral e Inorgânica, Instituto de Química de AraraquaraUniversité LavalUniversidade Estadual Paulista (Unesp)Asselin, JérémieRoy, CarlBoudreau, DenisMessaddeq, Younes [UNESP]Bouchareb, RihabMathieu, Patrick2015-05-15T13:30:24Z2015-05-15T13:30:24Z2014info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article13746-13749application/pdfhttp://pubs.rsc.org/en/Content/ArticleLanding/2014/CC/C4CC06075J#!divAbstractChemical Communications, v. 50, n. 89, p. 13746-13749, 2014.1359-7345http://hdl.handle.net/11449/12355210.1039/C4CC06075JISSN1359-7345-2014-50-89-13746-13749.pdf2998503841917815Currículo Lattesreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengChemical Communications6.2902,555info:eu-repo/semantics/openAccess2023-10-23T06:04:34Zoai:repositorio.unesp.br:11449/123552Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T15:40:45.247440Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Supported core-shell nanobiosensors for quantitative fluorescence imaging of extracellular pH |
title |
Supported core-shell nanobiosensors for quantitative fluorescence imaging of extracellular pH |
spellingShingle |
Supported core-shell nanobiosensors for quantitative fluorescence imaging of extracellular pH Asselin, Jérémie |
title_short |
Supported core-shell nanobiosensors for quantitative fluorescence imaging of extracellular pH |
title_full |
Supported core-shell nanobiosensors for quantitative fluorescence imaging of extracellular pH |
title_fullStr |
Supported core-shell nanobiosensors for quantitative fluorescence imaging of extracellular pH |
title_full_unstemmed |
Supported core-shell nanobiosensors for quantitative fluorescence imaging of extracellular pH |
title_sort |
Supported core-shell nanobiosensors for quantitative fluorescence imaging of extracellular pH |
author |
Asselin, Jérémie |
author_facet |
Asselin, Jérémie Roy, Carl Boudreau, Denis Messaddeq, Younes [UNESP] Bouchareb, Rihab Mathieu, Patrick |
author_role |
author |
author2 |
Roy, Carl Boudreau, Denis Messaddeq, Younes [UNESP] Bouchareb, Rihab Mathieu, Patrick |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Université Laval Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Asselin, Jérémie Roy, Carl Boudreau, Denis Messaddeq, Younes [UNESP] Bouchareb, Rihab Mathieu, Patrick |
description |
Covalent “click” cycloaddition was used to functionalize silica substrates with pH-sensitive nanoparticles, thus producing uniform and highly luminescent analytical devices usable in both commercial fluorimeters and fluorescence microscopes. Quantitative and spatially-resolved extracellular pH measurements were successfully achieved on live cardiac fibroblasts with these novel ion-sensitive surfaces. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014 2015-05-15T13:30:24Z 2015-05-15T13:30:24Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://pubs.rsc.org/en/Content/ArticleLanding/2014/CC/C4CC06075J#!divAbstract Chemical Communications, v. 50, n. 89, p. 13746-13749, 2014. 1359-7345 http://hdl.handle.net/11449/123552 10.1039/C4CC06075J ISSN1359-7345-2014-50-89-13746-13749.pdf 2998503841917815 |
url |
http://pubs.rsc.org/en/Content/ArticleLanding/2014/CC/C4CC06075J#!divAbstract http://hdl.handle.net/11449/123552 |
identifier_str_mv |
Chemical Communications, v. 50, n. 89, p. 13746-13749, 2014. 1359-7345 10.1039/C4CC06075J ISSN1359-7345-2014-50-89-13746-13749.pdf 2998503841917815 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Chemical Communications 6.290 2,555 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
13746-13749 application/pdf |
dc.source.none.fl_str_mv |
Currículo Lattes reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128548799512576 |