Physiological and biochemical responses of nile tilapia (Oreochromis niloticus) to acute trichlorfon exposure
Main Author: | |
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Publication Date: | 2020 |
Other Authors: | , , , , , , |
Format: | Article |
Language: | eng |
Source: | Repositório Institucional da UNESP |
Download full: | http://dx.doi.org/10.22034/IAR.2020.1904943.1071 http://hdl.handle.net/11449/207105 |
Summary: | Trichlorfon [TCF] is an organophosphate compound used to eliminate or control a variety of parasites in farmed fish. The physiological and biochemical responses of juvenile Nile tilapia were studied after 96 hours of exposure to TCF. The experiment was conducted randomly with two treatments: control and TCF (0.5 mg L-1). No mortality or changes in hematological profile were recorded for the fish. On the other hand, we found that TCF exposure caused behavioral, metabolic and hormonal changes that modified the response patterns of the immune and enzymatic defense system in muscle and liver tissues. Increased plasma cortisol and glucose combined with the reduction of acetylcholinesterase activity in muscle and liver tissue after 96-h of TCF exposure indicates chemical stress. In response to this harmful situation, we observed changes in the immune system that lead to an increased number of leukocytes, thrombocytes, monocytes, lysozyme and leukocyte respiratory burst activity. Furthermore, we associate the increased activity of glutathione-S-transferase in liver tissue as a strategy fish use to combat the effects of TCF. Thus, we conclude that TCF affects the physiologic parameters of Nile tilapia, which can generate irreversible situations of recovery of the clinical condition. Such fact highlights the need to search for new compounds that could replace TCF, that have no or few adverse effects on fish species. |
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Physiological and biochemical responses of nile tilapia (Oreochromis niloticus) to acute trichlorfon exposureAquacultureChemotherapyToxicologyTrichlorfonTrichlorfon [TCF] is an organophosphate compound used to eliminate or control a variety of parasites in farmed fish. The physiological and biochemical responses of juvenile Nile tilapia were studied after 96 hours of exposure to TCF. The experiment was conducted randomly with two treatments: control and TCF (0.5 mg L-1). No mortality or changes in hematological profile were recorded for the fish. On the other hand, we found that TCF exposure caused behavioral, metabolic and hormonal changes that modified the response patterns of the immune and enzymatic defense system in muscle and liver tissues. Increased plasma cortisol and glucose combined with the reduction of acetylcholinesterase activity in muscle and liver tissue after 96-h of TCF exposure indicates chemical stress. In response to this harmful situation, we observed changes in the immune system that lead to an increased number of leukocytes, thrombocytes, monocytes, lysozyme and leukocyte respiratory burst activity. Furthermore, we associate the increased activity of glutathione-S-transferase in liver tissue as a strategy fish use to combat the effects of TCF. Thus, we conclude that TCF affects the physiologic parameters of Nile tilapia, which can generate irreversible situations of recovery of the clinical condition. Such fact highlights the need to search for new compounds that could replace TCF, that have no or few adverse effects on fish species.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Joint Graduate Program in Physiological Sciences Federal University of São Carlos-UFSCar/São Paulo State University UNESP Campus AraraquaraState University of Campinas Institute of Animal Biology University city Zeferino Vaz-Barão GeraldoBrazilian Agricultural Research Corporation Embrapa Environment, Rodovia SP 340, Km 127,5 Caixa Postal 69Joint Graduate Program in Physiological Sciences Federal University of São Carlos-UFSCar/São Paulo State University UNESP Campus AraraquaraUniversidade Estadual Paulista (Unesp)Universidade Estadual de Campinas (UNICAMP)Empresa Brasileira de Pesquisa Agropecuária (EMBRAPA)Cardoso, Israel Luz [UNESP]Soares, Michelly Pereira [UNESP]De Angelis, Carolina [UNESP]Ferri, Giovanni HenriqueIshikawa, Marcia MayumiJonsson, Claudio MartinRantin, Francisco Tadeu [UNESP]Sampaio, Fernanda Garcia2021-06-25T10:49:01Z2021-06-25T10:49:01Z2020-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article243-253http://dx.doi.org/10.22034/IAR.2020.1904943.1071International Aquatic Research, v. 12, n. 4, p. 243-253, 2020.2008-69702008-4935http://hdl.handle.net/11449/20710510.22034/IAR.2020.1904943.10712-s2.0-85099116677Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengInternational Aquatic Researchinfo:eu-repo/semantics/openAccess2021-10-23T16:16:07Zoai:repositorio.unesp.br:11449/207105Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-23T16:16:07Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Physiological and biochemical responses of nile tilapia (Oreochromis niloticus) to acute trichlorfon exposure |
title |
Physiological and biochemical responses of nile tilapia (Oreochromis niloticus) to acute trichlorfon exposure |
spellingShingle |
Physiological and biochemical responses of nile tilapia (Oreochromis niloticus) to acute trichlorfon exposure Cardoso, Israel Luz [UNESP] Aquaculture Chemotherapy Toxicology Trichlorfon |
title_short |
Physiological and biochemical responses of nile tilapia (Oreochromis niloticus) to acute trichlorfon exposure |
title_full |
Physiological and biochemical responses of nile tilapia (Oreochromis niloticus) to acute trichlorfon exposure |
title_fullStr |
Physiological and biochemical responses of nile tilapia (Oreochromis niloticus) to acute trichlorfon exposure |
title_full_unstemmed |
Physiological and biochemical responses of nile tilapia (Oreochromis niloticus) to acute trichlorfon exposure |
title_sort |
Physiological and biochemical responses of nile tilapia (Oreochromis niloticus) to acute trichlorfon exposure |
author |
Cardoso, Israel Luz [UNESP] |
author_facet |
Cardoso, Israel Luz [UNESP] Soares, Michelly Pereira [UNESP] De Angelis, Carolina [UNESP] Ferri, Giovanni Henrique Ishikawa, Marcia Mayumi Jonsson, Claudio Martin Rantin, Francisco Tadeu [UNESP] Sampaio, Fernanda Garcia |
author_role |
author |
author2 |
Soares, Michelly Pereira [UNESP] De Angelis, Carolina [UNESP] Ferri, Giovanni Henrique Ishikawa, Marcia Mayumi Jonsson, Claudio Martin Rantin, Francisco Tadeu [UNESP] Sampaio, Fernanda Garcia |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Universidade Estadual de Campinas (UNICAMP) Empresa Brasileira de Pesquisa Agropecuária (EMBRAPA) |
dc.contributor.author.fl_str_mv |
Cardoso, Israel Luz [UNESP] Soares, Michelly Pereira [UNESP] De Angelis, Carolina [UNESP] Ferri, Giovanni Henrique Ishikawa, Marcia Mayumi Jonsson, Claudio Martin Rantin, Francisco Tadeu [UNESP] Sampaio, Fernanda Garcia |
dc.subject.por.fl_str_mv |
Aquaculture Chemotherapy Toxicology Trichlorfon |
topic |
Aquaculture Chemotherapy Toxicology Trichlorfon |
description |
Trichlorfon [TCF] is an organophosphate compound used to eliminate or control a variety of parasites in farmed fish. The physiological and biochemical responses of juvenile Nile tilapia were studied after 96 hours of exposure to TCF. The experiment was conducted randomly with two treatments: control and TCF (0.5 mg L-1). No mortality or changes in hematological profile were recorded for the fish. On the other hand, we found that TCF exposure caused behavioral, metabolic and hormonal changes that modified the response patterns of the immune and enzymatic defense system in muscle and liver tissues. Increased plasma cortisol and glucose combined with the reduction of acetylcholinesterase activity in muscle and liver tissue after 96-h of TCF exposure indicates chemical stress. In response to this harmful situation, we observed changes in the immune system that lead to an increased number of leukocytes, thrombocytes, monocytes, lysozyme and leukocyte respiratory burst activity. Furthermore, we associate the increased activity of glutathione-S-transferase in liver tissue as a strategy fish use to combat the effects of TCF. Thus, we conclude that TCF affects the physiologic parameters of Nile tilapia, which can generate irreversible situations of recovery of the clinical condition. Such fact highlights the need to search for new compounds that could replace TCF, that have no or few adverse effects on fish species. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-01 2021-06-25T10:49:01Z 2021-06-25T10:49:01Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.22034/IAR.2020.1904943.1071 International Aquatic Research, v. 12, n. 4, p. 243-253, 2020. 2008-6970 2008-4935 http://hdl.handle.net/11449/207105 10.22034/IAR.2020.1904943.1071 2-s2.0-85099116677 |
url |
http://dx.doi.org/10.22034/IAR.2020.1904943.1071 http://hdl.handle.net/11449/207105 |
identifier_str_mv |
International Aquatic Research, v. 12, n. 4, p. 243-253, 2020. 2008-6970 2008-4935 10.22034/IAR.2020.1904943.1071 2-s2.0-85099116677 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
International Aquatic Research |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
243-253 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1799965475184050176 |