Adjunctive use of antimicrobial photodynamic therapy in the treatment of medication-related osteonecrosis of the jaws: A case report

Detalhes bibliográficos
Autor(a) principal: Poli, Pier Paolo
Data de Publicação: 2018
Outros Autores: Souza, Francisley Ávila [UNESP], Maiorana, Carlo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1016/j.pdpdt.2018.06.004
http://hdl.handle.net/11449/176475
Resumo: Medication-related osteonecrosis of the jaws is a delayed healing condition commonly recognized as a serious adverse effect of antiresorptive therapy and is particularly associated with aminobisphosphonate treatment. In the present report, a 62-year-old osteoporotic female patient treated with intramuscular injections of clodronate for 3 years exhibited clinical signs of exposed necrotic bone and inflamed mucosa 4 months after tooth extractions in the mandibular interforaminal region. The treatment consisted of sequestrectomy, open-flap debridement, and adjunctive use of antimicrobial photodynamic therapy to decontaminate the affected hard and soft tissues. Successful results were obtained and maintained from both clinical and radiological aspects. No recurrence was observed up to 6 months of follow-up.
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spelling Adjunctive use of antimicrobial photodynamic therapy in the treatment of medication-related osteonecrosis of the jaws: A case reportBisphosphonatesDecontaminationOral surgeryOsteonecrosisPhotodynamic therapyMedication-related osteonecrosis of the jaws is a delayed healing condition commonly recognized as a serious adverse effect of antiresorptive therapy and is particularly associated with aminobisphosphonate treatment. In the present report, a 62-year-old osteoporotic female patient treated with intramuscular injections of clodronate for 3 years exhibited clinical signs of exposed necrotic bone and inflamed mucosa 4 months after tooth extractions in the mandibular interforaminal region. The treatment consisted of sequestrectomy, open-flap debridement, and adjunctive use of antimicrobial photodynamic therapy to decontaminate the affected hard and soft tissues. Successful results were obtained and maintained from both clinical and radiological aspects. No recurrence was observed up to 6 months of follow-up.Implant Center for Edentulism and Jawbone Atrophies Maxillofacial Surgery and Odontostomatology Unit Maggiore Policlinico Hospital University of Milan, Via Commenda 10Department of Surgery and Integrated Clinic Araçatuba Dental School São Paulo State University “Júlio de Mesquita Filho” - UNESP, Rua José Bonifácio, 1193 - Vila MendoncaDepartment of Surgery and Integrated Clinic Araçatuba Dental School São Paulo State University “Júlio de Mesquita Filho” - UNESP, Rua José Bonifácio, 1193 - Vila MendoncaUniversity of MilanUniversidade Estadual Paulista (Unesp)Poli, Pier PaoloSouza, Francisley Ávila [UNESP]Maiorana, Carlo2018-12-11T17:20:56Z2018-12-11T17:20:56Z2018-09-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article99-101application/pdfhttp://dx.doi.org/10.1016/j.pdpdt.2018.06.004Photodiagnosis and Photodynamic Therapy, v. 23, p. 99-101.1873-15971572-1000http://hdl.handle.net/11449/17647510.1016/j.pdpdt.2018.06.0042-s2.0-850487460582-s2.0-85048746058.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengPhotodiagnosis and Photodynamic Therapy0,647info:eu-repo/semantics/openAccess2023-11-21T06:08:25Zoai:repositorio.unesp.br:11449/176475Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-11-21T06:08:25Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Adjunctive use of antimicrobial photodynamic therapy in the treatment of medication-related osteonecrosis of the jaws: A case report
title Adjunctive use of antimicrobial photodynamic therapy in the treatment of medication-related osteonecrosis of the jaws: A case report
spellingShingle Adjunctive use of antimicrobial photodynamic therapy in the treatment of medication-related osteonecrosis of the jaws: A case report
Poli, Pier Paolo
Bisphosphonates
Decontamination
Oral surgery
Osteonecrosis
Photodynamic therapy
title_short Adjunctive use of antimicrobial photodynamic therapy in the treatment of medication-related osteonecrosis of the jaws: A case report
title_full Adjunctive use of antimicrobial photodynamic therapy in the treatment of medication-related osteonecrosis of the jaws: A case report
title_fullStr Adjunctive use of antimicrobial photodynamic therapy in the treatment of medication-related osteonecrosis of the jaws: A case report
title_full_unstemmed Adjunctive use of antimicrobial photodynamic therapy in the treatment of medication-related osteonecrosis of the jaws: A case report
title_sort Adjunctive use of antimicrobial photodynamic therapy in the treatment of medication-related osteonecrosis of the jaws: A case report
author Poli, Pier Paolo
author_facet Poli, Pier Paolo
Souza, Francisley Ávila [UNESP]
Maiorana, Carlo
author_role author
author2 Souza, Francisley Ávila [UNESP]
Maiorana, Carlo
author2_role author
author
dc.contributor.none.fl_str_mv University of Milan
Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Poli, Pier Paolo
Souza, Francisley Ávila [UNESP]
Maiorana, Carlo
dc.subject.por.fl_str_mv Bisphosphonates
Decontamination
Oral surgery
Osteonecrosis
Photodynamic therapy
topic Bisphosphonates
Decontamination
Oral surgery
Osteonecrosis
Photodynamic therapy
description Medication-related osteonecrosis of the jaws is a delayed healing condition commonly recognized as a serious adverse effect of antiresorptive therapy and is particularly associated with aminobisphosphonate treatment. In the present report, a 62-year-old osteoporotic female patient treated with intramuscular injections of clodronate for 3 years exhibited clinical signs of exposed necrotic bone and inflamed mucosa 4 months after tooth extractions in the mandibular interforaminal region. The treatment consisted of sequestrectomy, open-flap debridement, and adjunctive use of antimicrobial photodynamic therapy to decontaminate the affected hard and soft tissues. Successful results were obtained and maintained from both clinical and radiological aspects. No recurrence was observed up to 6 months of follow-up.
publishDate 2018
dc.date.none.fl_str_mv 2018-12-11T17:20:56Z
2018-12-11T17:20:56Z
2018-09-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/j.pdpdt.2018.06.004
Photodiagnosis and Photodynamic Therapy, v. 23, p. 99-101.
1873-1597
1572-1000
http://hdl.handle.net/11449/176475
10.1016/j.pdpdt.2018.06.004
2-s2.0-85048746058
2-s2.0-85048746058.pdf
url http://dx.doi.org/10.1016/j.pdpdt.2018.06.004
http://hdl.handle.net/11449/176475
identifier_str_mv Photodiagnosis and Photodynamic Therapy, v. 23, p. 99-101.
1873-1597
1572-1000
10.1016/j.pdpdt.2018.06.004
2-s2.0-85048746058
2-s2.0-85048746058.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Photodiagnosis and Photodynamic Therapy
0,647
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 99-101
application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1799965013028372480

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