Antimicrobial photodynamic therapy on teeth with molar incisor hypomineralization-controlled clinical trial
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1097/MD.0000000000017355 http://hdl.handle.net/11449/194912 |
Resumo: | Background: Molar incisor hypomineralization (MIH) is a change in the formation of dental enamel of systemic origin that affects at least one of the first 4 permanent molars and usually affects incisors. During the eruption, the affected surfaces tend to fracture, exposing the dentin, which causes excessive sensitivity in addition to making the region very susceptible to the appearance of carious lesions. The objective of this research will be to evaluate the clinical effect of antimicrobial photodynamic therapy (aPDT) in permanent teeth with severe and sensitive MIH. Methods: The methodology will be based on the selection of patients from 6 to 12 years of age with permanent molar teeth, randomly divided in 2 groups. The selected teeth should have MIH on the occlusal surface, indicated for clinical restorative treatment. In Group 1, aPDT will be applied for the treatment of infected dentin. Afterward, the teeth will be restored with high viscosity glass ionomer cement. In Group 2, the removal of the softened dentin around the side walls of the cavity with sharp dentine curettes and posterior restoration with high viscosity glass ionomer cement will be performed. All patients will have clinical and radiographic followup with a time interval of 6 and 12 months. The data obtained will be submitted to descriptive statistical analysis to evaluate the association of categorical variables. Chi-square test and Fisher exact test will be applied, to analyze the correlation between the continuous variables, Pearson correlation test will be applied. For the analysis of dentin density in the scanned radiographic images and the microbiological results for colony-forming units, ANOVA and Kruskal-Wallis will be applied. Discussion: Often in the presence of severe MIH, the presence of dentin sensitivity is also associated with caries lesion, making it even more necessary to respect the principles of minimal intervention. |
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Antimicrobial photodynamic therapy on teeth with molar incisor hypomineralization-controlled clinical trialARTlaser therapyMIHPDTBackground: Molar incisor hypomineralization (MIH) is a change in the formation of dental enamel of systemic origin that affects at least one of the first 4 permanent molars and usually affects incisors. During the eruption, the affected surfaces tend to fracture, exposing the dentin, which causes excessive sensitivity in addition to making the region very susceptible to the appearance of carious lesions. The objective of this research will be to evaluate the clinical effect of antimicrobial photodynamic therapy (aPDT) in permanent teeth with severe and sensitive MIH. Methods: The methodology will be based on the selection of patients from 6 to 12 years of age with permanent molar teeth, randomly divided in 2 groups. The selected teeth should have MIH on the occlusal surface, indicated for clinical restorative treatment. In Group 1, aPDT will be applied for the treatment of infected dentin. Afterward, the teeth will be restored with high viscosity glass ionomer cement. In Group 2, the removal of the softened dentin around the side walls of the cavity with sharp dentine curettes and posterior restoration with high viscosity glass ionomer cement will be performed. All patients will have clinical and radiographic followup with a time interval of 6 and 12 months. The data obtained will be submitted to descriptive statistical analysis to evaluate the association of categorical variables. Chi-square test and Fisher exact test will be applied, to analyze the correlation between the continuous variables, Pearson correlation test will be applied. For the analysis of dentin density in the scanned radiographic images and the microbiological results for colony-forming units, ANOVA and Kruskal-Wallis will be applied. Discussion: Often in the presence of severe MIH, the presence of dentin sensitivity is also associated with caries lesion, making it even more necessary to respect the principles of minimal intervention.University Nove de JulhoFACIPLAC, Brasilia, DF, BrazilUniv Fed Minas Gerais, Dept Pediat Dent & Orthodont, Belo Horizonte, MG, BrazilUniv Nove Julho, Biophoton Appl Hlth Sci, Maua, SP, BrazilUniceplac, Brasilia, DF, BrazilUniv Julio de Mesquita Filho, Araraquara, SP, BrazilUniv Julio de Mesquita Filho, Araraquara, SP, BrazilLippincott Williams & WilkinsFACIPLACUniversidade Federal de Minas Gerais (UFMG)Univ Nove JulhoUniceplacUniversidade Estadual Paulista (Unesp)Santos Vieira, Leticia DinizBenini Paschoal, Marco AurelioMotta, Pamella de BarrosFerri, Elza PadilhaPagani Vieira Ribeiro, Caroline DinizMartins dos Santos-Pinto, Lourdes Aparecida [UNESP]Motta, Lara JansiskiLeal Goncalves, Marcela LeticiaRatto Tempestini Horliana, Anna CarolinaSantos Fernandes, Kristianne PortaMesquita Ferrari, Raquel AgnelliDeana, Alexandre MeloBussadori, Sandra Kalil2020-12-10T16:58:30Z2020-12-10T16:58:30Z2019-09-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article7http://dx.doi.org/10.1097/MD.0000000000017355Medicine. Philadelphia: Lippincott Williams & Wilkins, v. 98, n. 39, 7 p., 2019.0025-7974http://hdl.handle.net/11449/19491210.1097/MD.0000000000017355WOS:000491346400088Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengMedicineinfo:eu-repo/semantics/openAccess2021-10-23T01:35:50Zoai:repositorio.unesp.br:11449/194912Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T20:53:56.878347Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Antimicrobial photodynamic therapy on teeth with molar incisor hypomineralization-controlled clinical trial |
title |
Antimicrobial photodynamic therapy on teeth with molar incisor hypomineralization-controlled clinical trial |
spellingShingle |
Antimicrobial photodynamic therapy on teeth with molar incisor hypomineralization-controlled clinical trial Santos Vieira, Leticia Diniz ART laser therapy MIH PDT |
title_short |
Antimicrobial photodynamic therapy on teeth with molar incisor hypomineralization-controlled clinical trial |
title_full |
Antimicrobial photodynamic therapy on teeth with molar incisor hypomineralization-controlled clinical trial |
title_fullStr |
Antimicrobial photodynamic therapy on teeth with molar incisor hypomineralization-controlled clinical trial |
title_full_unstemmed |
Antimicrobial photodynamic therapy on teeth with molar incisor hypomineralization-controlled clinical trial |
title_sort |
Antimicrobial photodynamic therapy on teeth with molar incisor hypomineralization-controlled clinical trial |
author |
Santos Vieira, Leticia Diniz |
author_facet |
Santos Vieira, Leticia Diniz Benini Paschoal, Marco Aurelio Motta, Pamella de Barros Ferri, Elza Padilha Pagani Vieira Ribeiro, Caroline Diniz Martins dos Santos-Pinto, Lourdes Aparecida [UNESP] Motta, Lara Jansiski Leal Goncalves, Marcela Leticia Ratto Tempestini Horliana, Anna Carolina Santos Fernandes, Kristianne Porta Mesquita Ferrari, Raquel Agnelli Deana, Alexandre Melo Bussadori, Sandra Kalil |
author_role |
author |
author2 |
Benini Paschoal, Marco Aurelio Motta, Pamella de Barros Ferri, Elza Padilha Pagani Vieira Ribeiro, Caroline Diniz Martins dos Santos-Pinto, Lourdes Aparecida [UNESP] Motta, Lara Jansiski Leal Goncalves, Marcela Leticia Ratto Tempestini Horliana, Anna Carolina Santos Fernandes, Kristianne Porta Mesquita Ferrari, Raquel Agnelli Deana, Alexandre Melo Bussadori, Sandra Kalil |
author2_role |
author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
FACIPLAC Universidade Federal de Minas Gerais (UFMG) Univ Nove Julho Uniceplac Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Santos Vieira, Leticia Diniz Benini Paschoal, Marco Aurelio Motta, Pamella de Barros Ferri, Elza Padilha Pagani Vieira Ribeiro, Caroline Diniz Martins dos Santos-Pinto, Lourdes Aparecida [UNESP] Motta, Lara Jansiski Leal Goncalves, Marcela Leticia Ratto Tempestini Horliana, Anna Carolina Santos Fernandes, Kristianne Porta Mesquita Ferrari, Raquel Agnelli Deana, Alexandre Melo Bussadori, Sandra Kalil |
dc.subject.por.fl_str_mv |
ART laser therapy MIH PDT |
topic |
ART laser therapy MIH PDT |
description |
Background: Molar incisor hypomineralization (MIH) is a change in the formation of dental enamel of systemic origin that affects at least one of the first 4 permanent molars and usually affects incisors. During the eruption, the affected surfaces tend to fracture, exposing the dentin, which causes excessive sensitivity in addition to making the region very susceptible to the appearance of carious lesions. The objective of this research will be to evaluate the clinical effect of antimicrobial photodynamic therapy (aPDT) in permanent teeth with severe and sensitive MIH. Methods: The methodology will be based on the selection of patients from 6 to 12 years of age with permanent molar teeth, randomly divided in 2 groups. The selected teeth should have MIH on the occlusal surface, indicated for clinical restorative treatment. In Group 1, aPDT will be applied for the treatment of infected dentin. Afterward, the teeth will be restored with high viscosity glass ionomer cement. In Group 2, the removal of the softened dentin around the side walls of the cavity with sharp dentine curettes and posterior restoration with high viscosity glass ionomer cement will be performed. All patients will have clinical and radiographic followup with a time interval of 6 and 12 months. The data obtained will be submitted to descriptive statistical analysis to evaluate the association of categorical variables. Chi-square test and Fisher exact test will be applied, to analyze the correlation between the continuous variables, Pearson correlation test will be applied. For the analysis of dentin density in the scanned radiographic images and the microbiological results for colony-forming units, ANOVA and Kruskal-Wallis will be applied. Discussion: Often in the presence of severe MIH, the presence of dentin sensitivity is also associated with caries lesion, making it even more necessary to respect the principles of minimal intervention. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-09-01 2020-12-10T16:58:30Z 2020-12-10T16:58:30Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1097/MD.0000000000017355 Medicine. Philadelphia: Lippincott Williams & Wilkins, v. 98, n. 39, 7 p., 2019. 0025-7974 http://hdl.handle.net/11449/194912 10.1097/MD.0000000000017355 WOS:000491346400088 |
url |
http://dx.doi.org/10.1097/MD.0000000000017355 http://hdl.handle.net/11449/194912 |
identifier_str_mv |
Medicine. Philadelphia: Lippincott Williams & Wilkins, v. 98, n. 39, 7 p., 2019. 0025-7974 10.1097/MD.0000000000017355 WOS:000491346400088 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Medicine |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
7 |
dc.publisher.none.fl_str_mv |
Lippincott Williams & Wilkins |
publisher.none.fl_str_mv |
Lippincott Williams & Wilkins |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129261770375168 |