Antimicrobial photodynamic therapy on teeth with molar incisor hypomineralization-controlled clinical trial

Detalhes bibliográficos
Autor(a) principal: Santos Vieira, Leticia Diniz
Data de Publicação: 2019
Outros Autores: Benini Paschoal, Marco Aurelio, Motta, Pamella de Barros, Ferri, Elza Padilha, Pagani Vieira Ribeiro, Caroline Diniz, Martins dos Santos-Pinto, Lourdes Aparecida [UNESP], Motta, Lara Jansiski, Leal Goncalves, Marcela Leticia, Ratto Tempestini Horliana, Anna Carolina, Santos Fernandes, Kristianne Porta, Mesquita Ferrari, Raquel Agnelli, Deana, Alexandre Melo, Bussadori, Sandra Kalil
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1097/MD.0000000000017355
http://hdl.handle.net/11449/194912
Resumo: Background: Molar incisor hypomineralization (MIH) is a change in the formation of dental enamel of systemic origin that affects at least one of the first 4 permanent molars and usually affects incisors. During the eruption, the affected surfaces tend to fracture, exposing the dentin, which causes excessive sensitivity in addition to making the region very susceptible to the appearance of carious lesions. The objective of this research will be to evaluate the clinical effect of antimicrobial photodynamic therapy (aPDT) in permanent teeth with severe and sensitive MIH. Methods: The methodology will be based on the selection of patients from 6 to 12 years of age with permanent molar teeth, randomly divided in 2 groups. The selected teeth should have MIH on the occlusal surface, indicated for clinical restorative treatment. In Group 1, aPDT will be applied for the treatment of infected dentin. Afterward, the teeth will be restored with high viscosity glass ionomer cement. In Group 2, the removal of the softened dentin around the side walls of the cavity with sharp dentine curettes and posterior restoration with high viscosity glass ionomer cement will be performed. All patients will have clinical and radiographic followup with a time interval of 6 and 12 months. The data obtained will be submitted to descriptive statistical analysis to evaluate the association of categorical variables. Chi-square test and Fisher exact test will be applied, to analyze the correlation between the continuous variables, Pearson correlation test will be applied. For the analysis of dentin density in the scanned radiographic images and the microbiological results for colony-forming units, ANOVA and Kruskal-Wallis will be applied. Discussion: Often in the presence of severe MIH, the presence of dentin sensitivity is also associated with caries lesion, making it even more necessary to respect the principles of minimal intervention.
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spelling Antimicrobial photodynamic therapy on teeth with molar incisor hypomineralization-controlled clinical trialARTlaser therapyMIHPDTBackground: Molar incisor hypomineralization (MIH) is a change in the formation of dental enamel of systemic origin that affects at least one of the first 4 permanent molars and usually affects incisors. During the eruption, the affected surfaces tend to fracture, exposing the dentin, which causes excessive sensitivity in addition to making the region very susceptible to the appearance of carious lesions. The objective of this research will be to evaluate the clinical effect of antimicrobial photodynamic therapy (aPDT) in permanent teeth with severe and sensitive MIH. Methods: The methodology will be based on the selection of patients from 6 to 12 years of age with permanent molar teeth, randomly divided in 2 groups. The selected teeth should have MIH on the occlusal surface, indicated for clinical restorative treatment. In Group 1, aPDT will be applied for the treatment of infected dentin. Afterward, the teeth will be restored with high viscosity glass ionomer cement. In Group 2, the removal of the softened dentin around the side walls of the cavity with sharp dentine curettes and posterior restoration with high viscosity glass ionomer cement will be performed. All patients will have clinical and radiographic followup with a time interval of 6 and 12 months. The data obtained will be submitted to descriptive statistical analysis to evaluate the association of categorical variables. Chi-square test and Fisher exact test will be applied, to analyze the correlation between the continuous variables, Pearson correlation test will be applied. For the analysis of dentin density in the scanned radiographic images and the microbiological results for colony-forming units, ANOVA and Kruskal-Wallis will be applied. Discussion: Often in the presence of severe MIH, the presence of dentin sensitivity is also associated with caries lesion, making it even more necessary to respect the principles of minimal intervention.University Nove de JulhoFACIPLAC, Brasilia, DF, BrazilUniv Fed Minas Gerais, Dept Pediat Dent & Orthodont, Belo Horizonte, MG, BrazilUniv Nove Julho, Biophoton Appl Hlth Sci, Maua, SP, BrazilUniceplac, Brasilia, DF, BrazilUniv Julio de Mesquita Filho, Araraquara, SP, BrazilUniv Julio de Mesquita Filho, Araraquara, SP, BrazilLippincott Williams & WilkinsFACIPLACUniversidade Federal de Minas Gerais (UFMG)Univ Nove JulhoUniceplacUniversidade Estadual Paulista (Unesp)Santos Vieira, Leticia DinizBenini Paschoal, Marco AurelioMotta, Pamella de BarrosFerri, Elza PadilhaPagani Vieira Ribeiro, Caroline DinizMartins dos Santos-Pinto, Lourdes Aparecida [UNESP]Motta, Lara JansiskiLeal Goncalves, Marcela LeticiaRatto Tempestini Horliana, Anna CarolinaSantos Fernandes, Kristianne PortaMesquita Ferrari, Raquel AgnelliDeana, Alexandre MeloBussadori, Sandra Kalil2020-12-10T16:58:30Z2020-12-10T16:58:30Z2019-09-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article7http://dx.doi.org/10.1097/MD.0000000000017355Medicine. Philadelphia: Lippincott Williams & Wilkins, v. 98, n. 39, 7 p., 2019.0025-7974http://hdl.handle.net/11449/19491210.1097/MD.0000000000017355WOS:000491346400088Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengMedicineinfo:eu-repo/semantics/openAccess2021-10-23T01:35:50Zoai:repositorio.unesp.br:11449/194912Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T20:53:56.878347Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Antimicrobial photodynamic therapy on teeth with molar incisor hypomineralization-controlled clinical trial
title Antimicrobial photodynamic therapy on teeth with molar incisor hypomineralization-controlled clinical trial
spellingShingle Antimicrobial photodynamic therapy on teeth with molar incisor hypomineralization-controlled clinical trial
Santos Vieira, Leticia Diniz
ART
laser therapy
MIH
PDT
title_short Antimicrobial photodynamic therapy on teeth with molar incisor hypomineralization-controlled clinical trial
title_full Antimicrobial photodynamic therapy on teeth with molar incisor hypomineralization-controlled clinical trial
title_fullStr Antimicrobial photodynamic therapy on teeth with molar incisor hypomineralization-controlled clinical trial
title_full_unstemmed Antimicrobial photodynamic therapy on teeth with molar incisor hypomineralization-controlled clinical trial
title_sort Antimicrobial photodynamic therapy on teeth with molar incisor hypomineralization-controlled clinical trial
author Santos Vieira, Leticia Diniz
author_facet Santos Vieira, Leticia Diniz
Benini Paschoal, Marco Aurelio
Motta, Pamella de Barros
Ferri, Elza Padilha
Pagani Vieira Ribeiro, Caroline Diniz
Martins dos Santos-Pinto, Lourdes Aparecida [UNESP]
Motta, Lara Jansiski
Leal Goncalves, Marcela Leticia
Ratto Tempestini Horliana, Anna Carolina
Santos Fernandes, Kristianne Porta
Mesquita Ferrari, Raquel Agnelli
Deana, Alexandre Melo
Bussadori, Sandra Kalil
author_role author
author2 Benini Paschoal, Marco Aurelio
Motta, Pamella de Barros
Ferri, Elza Padilha
Pagani Vieira Ribeiro, Caroline Diniz
Martins dos Santos-Pinto, Lourdes Aparecida [UNESP]
Motta, Lara Jansiski
Leal Goncalves, Marcela Leticia
Ratto Tempestini Horliana, Anna Carolina
Santos Fernandes, Kristianne Porta
Mesquita Ferrari, Raquel Agnelli
Deana, Alexandre Melo
Bussadori, Sandra Kalil
author2_role author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv FACIPLAC
Universidade Federal de Minas Gerais (UFMG)
Univ Nove Julho
Uniceplac
Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Santos Vieira, Leticia Diniz
Benini Paschoal, Marco Aurelio
Motta, Pamella de Barros
Ferri, Elza Padilha
Pagani Vieira Ribeiro, Caroline Diniz
Martins dos Santos-Pinto, Lourdes Aparecida [UNESP]
Motta, Lara Jansiski
Leal Goncalves, Marcela Leticia
Ratto Tempestini Horliana, Anna Carolina
Santos Fernandes, Kristianne Porta
Mesquita Ferrari, Raquel Agnelli
Deana, Alexandre Melo
Bussadori, Sandra Kalil
dc.subject.por.fl_str_mv ART
laser therapy
MIH
PDT
topic ART
laser therapy
MIH
PDT
description Background: Molar incisor hypomineralization (MIH) is a change in the formation of dental enamel of systemic origin that affects at least one of the first 4 permanent molars and usually affects incisors. During the eruption, the affected surfaces tend to fracture, exposing the dentin, which causes excessive sensitivity in addition to making the region very susceptible to the appearance of carious lesions. The objective of this research will be to evaluate the clinical effect of antimicrobial photodynamic therapy (aPDT) in permanent teeth with severe and sensitive MIH. Methods: The methodology will be based on the selection of patients from 6 to 12 years of age with permanent molar teeth, randomly divided in 2 groups. The selected teeth should have MIH on the occlusal surface, indicated for clinical restorative treatment. In Group 1, aPDT will be applied for the treatment of infected dentin. Afterward, the teeth will be restored with high viscosity glass ionomer cement. In Group 2, the removal of the softened dentin around the side walls of the cavity with sharp dentine curettes and posterior restoration with high viscosity glass ionomer cement will be performed. All patients will have clinical and radiographic followup with a time interval of 6 and 12 months. The data obtained will be submitted to descriptive statistical analysis to evaluate the association of categorical variables. Chi-square test and Fisher exact test will be applied, to analyze the correlation between the continuous variables, Pearson correlation test will be applied. For the analysis of dentin density in the scanned radiographic images and the microbiological results for colony-forming units, ANOVA and Kruskal-Wallis will be applied. Discussion: Often in the presence of severe MIH, the presence of dentin sensitivity is also associated with caries lesion, making it even more necessary to respect the principles of minimal intervention.
publishDate 2019
dc.date.none.fl_str_mv 2019-09-01
2020-12-10T16:58:30Z
2020-12-10T16:58:30Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1097/MD.0000000000017355
Medicine. Philadelphia: Lippincott Williams & Wilkins, v. 98, n. 39, 7 p., 2019.
0025-7974
http://hdl.handle.net/11449/194912
10.1097/MD.0000000000017355
WOS:000491346400088
url http://dx.doi.org/10.1097/MD.0000000000017355
http://hdl.handle.net/11449/194912
identifier_str_mv Medicine. Philadelphia: Lippincott Williams & Wilkins, v. 98, n. 39, 7 p., 2019.
0025-7974
10.1097/MD.0000000000017355
WOS:000491346400088
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Medicine
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 7
dc.publisher.none.fl_str_mv Lippincott Williams & Wilkins
publisher.none.fl_str_mv Lippincott Williams & Wilkins
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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