In vitro production of bovine embryos: Cumulus/granulosa cell gene expression patterns point to early atresia as beneficial for oocyte competence

Detalhes bibliográficos
Autor(a) principal: Mazzoni, Gianluca
Data de Publicação: 2017
Outros Autores: Razza, Eduardo, Pedersen, Hanne S., Secher, Jan, Kadarmideen, Haja N., Callesen, Henrik, Stroebech, Lotte, Freude, Kristine, Hyttel, Poul
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.21451/1984-3143-AR990
http://hdl.handle.net/11449/231415
Resumo: In vitro production (IVP) of bovine embryos has become widespread technology implemented in cattle breeding and production. Here, we review novel data on cumulus/granulosa cell gene expression, as determined by RNAseq on cellular material from pooled follicular fluids at the single animal level, and relate these finding to previous data on oocyte developmental competence and ultrastructure. The cumulus/granulosa cell gene expression patterns indicate that early follicular atresia is associated with increased blastocyst yield and this hypothesis is supported by previous data on oocyte competence and ultrastructure.
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spelling In vitro production of bovine embryos: Cumulus/granulosa cell gene expression patterns point to early atresia as beneficial for oocyte competenceAtresiaBiomarkersCattleGranulosa cellsIVPOocyte competenceTranscriptomicsIn vitro production (IVP) of bovine embryos has become widespread technology implemented in cattle breeding and production. Here, we review novel data on cumulus/granulosa cell gene expression, as determined by RNAseq on cellular material from pooled follicular fluids at the single animal level, and relate these finding to previous data on oocyte developmental competence and ultrastructure. The cumulus/granulosa cell gene expression patterns indicate that early follicular atresia is associated with increased blastocyst yield and this hypothesis is supported by previous data on oocyte competence and ultrastructure.Department of Veterinary and Animal Sciences University of CopenhagenDepartment of Pharmacology Institute of Bioscience University of São Paulo State, Distrito de Rubião Junior s/nDepartment of Animal Science Aarhus UniversityDepartment of Bio and Health Informatics Technical University of DenmarkEmbryoTrans Biotech ApSUniversity of CopenhagenUniversidade de São Paulo (USP)Aarhus UniversityTechnical University of DenmarkEmbryoTrans Biotech ApSMazzoni, GianlucaRazza, EduardoPedersen, Hanne S.Secher, JanKadarmideen, Haja N.Callesen, HenrikStroebech, LotteFreude, KristineHyttel, Poul2022-04-29T08:45:21Z2022-04-29T08:45:21Z2017-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article482-489http://dx.doi.org/10.21451/1984-3143-AR990Animal Reproduction, v. 14, n. 3, p. 482-489, 2017.1984-31431806-9614http://hdl.handle.net/11449/23141510.21451/1984-3143-AR9902-s2.0-85044511925Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengAnimal Reproductioninfo:eu-repo/semantics/openAccess2022-04-29T08:45:21Zoai:repositorio.unesp.br:11449/231415Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T15:30:14.083170Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv In vitro production of bovine embryos: Cumulus/granulosa cell gene expression patterns point to early atresia as beneficial for oocyte competence
title In vitro production of bovine embryos: Cumulus/granulosa cell gene expression patterns point to early atresia as beneficial for oocyte competence
spellingShingle In vitro production of bovine embryos: Cumulus/granulosa cell gene expression patterns point to early atresia as beneficial for oocyte competence
Mazzoni, Gianluca
Atresia
Biomarkers
Cattle
Granulosa cells
IVP
Oocyte competence
Transcriptomics
title_short In vitro production of bovine embryos: Cumulus/granulosa cell gene expression patterns point to early atresia as beneficial for oocyte competence
title_full In vitro production of bovine embryos: Cumulus/granulosa cell gene expression patterns point to early atresia as beneficial for oocyte competence
title_fullStr In vitro production of bovine embryos: Cumulus/granulosa cell gene expression patterns point to early atresia as beneficial for oocyte competence
title_full_unstemmed In vitro production of bovine embryos: Cumulus/granulosa cell gene expression patterns point to early atresia as beneficial for oocyte competence
title_sort In vitro production of bovine embryos: Cumulus/granulosa cell gene expression patterns point to early atresia as beneficial for oocyte competence
author Mazzoni, Gianluca
author_facet Mazzoni, Gianluca
Razza, Eduardo
Pedersen, Hanne S.
Secher, Jan
Kadarmideen, Haja N.
Callesen, Henrik
Stroebech, Lotte
Freude, Kristine
Hyttel, Poul
author_role author
author2 Razza, Eduardo
Pedersen, Hanne S.
Secher, Jan
Kadarmideen, Haja N.
Callesen, Henrik
Stroebech, Lotte
Freude, Kristine
Hyttel, Poul
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv University of Copenhagen
Universidade de São Paulo (USP)
Aarhus University
Technical University of Denmark
EmbryoTrans Biotech ApS
dc.contributor.author.fl_str_mv Mazzoni, Gianluca
Razza, Eduardo
Pedersen, Hanne S.
Secher, Jan
Kadarmideen, Haja N.
Callesen, Henrik
Stroebech, Lotte
Freude, Kristine
Hyttel, Poul
dc.subject.por.fl_str_mv Atresia
Biomarkers
Cattle
Granulosa cells
IVP
Oocyte competence
Transcriptomics
topic Atresia
Biomarkers
Cattle
Granulosa cells
IVP
Oocyte competence
Transcriptomics
description In vitro production (IVP) of bovine embryos has become widespread technology implemented in cattle breeding and production. Here, we review novel data on cumulus/granulosa cell gene expression, as determined by RNAseq on cellular material from pooled follicular fluids at the single animal level, and relate these finding to previous data on oocyte developmental competence and ultrastructure. The cumulus/granulosa cell gene expression patterns indicate that early follicular atresia is associated with increased blastocyst yield and this hypothesis is supported by previous data on oocyte competence and ultrastructure.
publishDate 2017
dc.date.none.fl_str_mv 2017-01-01
2022-04-29T08:45:21Z
2022-04-29T08:45:21Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.21451/1984-3143-AR990
Animal Reproduction, v. 14, n. 3, p. 482-489, 2017.
1984-3143
1806-9614
http://hdl.handle.net/11449/231415
10.21451/1984-3143-AR990
2-s2.0-85044511925
url http://dx.doi.org/10.21451/1984-3143-AR990
http://hdl.handle.net/11449/231415
identifier_str_mv Animal Reproduction, v. 14, n. 3, p. 482-489, 2017.
1984-3143
1806-9614
10.21451/1984-3143-AR990
2-s2.0-85044511925
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Animal Reproduction
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 482-489
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808128522253762560

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