Paracoccidioidomycosis with sarcoid-like lesions: a diagnostic challenge

• Autor(a) principal: Milanez Morgado de Abreu, Marilda Aparecida
• Data de Publicação: 2017
• Outros Autores: Lastoria, Joel Carlos [UNESP], Arruda Mattos, Antonio Luiz de, Avelar Alchorne, Mauricio Mota de
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://dx.doi.org/10.1590/0037-8682-0246-2016; http://hdl.handle.net/11449/162852
• topic: Diagnostic errors; Leprosy; Paracoccidioidomycosis

Clinical presentation of paracoccidioidomycosis (PCM) can be diverse. Morphology and quantity of skin lesions depends on interactions between host immunity and fungus virulence. Diagnosis can be a challenge considering that this fungus has low virulence and some individuals have immunity to microorganism, which results in well-marked granulomas without visible microorganisms. We report herein a clinical presentation of sarcoid-like PCM, initially diagnosed as tuberculoid leprosy. This rare type of PCM is often mistaken for other types of chronic granulomatous diseases. Diagnosis was confirmed after 4 years when a special stain analysis helped in the identification of the specific etiologic agent.