Influence of the elevation of the left ventricular diastolic pressure on the values of the first temporal derivative of the ventricular pressure (dP/dt)

Detalhes bibliográficos
Autor(a) principal: Okoshi, Katashi [UNESP]
Data de Publicação: 1999
Outros Autores: Fioretto, José Roberto [UNESP], Bonatto, Rossano César [UNESP], Tornero, Maria Teresinha Trovarelli [UNESP], Tucci, Paulo José [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/S0066-782X1999000700004
http://hdl.handle.net/11449/11267
Resumo: PURPOSE: To assess the effects of the elevation of the left ventricular end-diastolic pressure (LVEDP) on the value of the 1st temporal derivative of the ventricular pressure (dP/dt). METHODS: Nineteen anesthetized dogs were studied. The dogs were mechanically ventilated and underwent thoracotomy with parasympathetic nervous system block. The LVEDP was controlled with the use of a perfusion circuit connected to the left atrium and adjusted to the height of a reservoir. The elevation of the LVEDP was achieved by a sudden increase in the height of a reservoir filled with blood. Continuous recordings of the electrocardiogram, the aortic and ventricular pressures and the dP/dt were performed. RESULTS: Elevation of the LVEDP did not result in any variation of the heart rate (167±16.0bpm, before the procedure; 167±15.5bpm, after the procedure). All the other variables assessed, including systolic blood pressure (128±18.3mmHg and 150±21.5mmHg), diastolic blood pressure (98±16.9mmHg and 115±19.8mmHg), LVEDP (5.5±2.49 and 9.3±3.60mmHg), and dP/dt (4,855 ± 1,082 mmHg/s and 5,149±1,242mmHg/s) showed significant increases following the expansion of the ventricular cavity. Although the elevation of the dP/dt was statistically significant, 6 dogs curiously showed a decrease in the values of dP/dt. CONCLUSION: Sudden elevation of the LVEDP resulted in increased values of dP/dt; however, in some dogs, this response was not uniform.
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spelling Influence of the elevation of the left ventricular diastolic pressure on the values of the first temporal derivative of the ventricular pressure (dP/dt)Frank-Starling mechanismdP/dtventricular functionPURPOSE: To assess the effects of the elevation of the left ventricular end-diastolic pressure (LVEDP) on the value of the 1st temporal derivative of the ventricular pressure (dP/dt). METHODS: Nineteen anesthetized dogs were studied. The dogs were mechanically ventilated and underwent thoracotomy with parasympathetic nervous system block. The LVEDP was controlled with the use of a perfusion circuit connected to the left atrium and adjusted to the height of a reservoir. The elevation of the LVEDP was achieved by a sudden increase in the height of a reservoir filled with blood. Continuous recordings of the electrocardiogram, the aortic and ventricular pressures and the dP/dt were performed. RESULTS: Elevation of the LVEDP did not result in any variation of the heart rate (167±16.0bpm, before the procedure; 167±15.5bpm, after the procedure). All the other variables assessed, including systolic blood pressure (128±18.3mmHg and 150±21.5mmHg), diastolic blood pressure (98±16.9mmHg and 115±19.8mmHg), LVEDP (5.5±2.49 and 9.3±3.60mmHg), and dP/dt (4,855 ± 1,082 mmHg/s and 5,149±1,242mmHg/s) showed significant increases following the expansion of the ventricular cavity. Although the elevation of the dP/dt was statistically significant, 6 dogs curiously showed a decrease in the values of dP/dt. CONCLUSION: Sudden elevation of the LVEDP resulted in increased values of dP/dt; however, in some dogs, this response was not uniform.Universidade Estadual de São Paulo Faculdade de Medicina de BotucatuSociedade Brasileira de Cardiologia (SBC)Universidade Estadual Paulista (Unesp)Okoshi, Katashi [UNESP]Fioretto, José Roberto [UNESP]Bonatto, Rossano César [UNESP]Tornero, Maria Teresinha Trovarelli [UNESP]Tucci, Paulo José [UNESP]2014-05-20T13:32:57Z2014-05-20T13:32:57Z1999-07-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article42-46application/pdfhttp://dx.doi.org/10.1590/S0066-782X1999000700004Arquivos Brasileiros de Cardiologia. Sociedade Brasileira de Cardiologia - SBC, v. 73, n. 1, p. 42-46, 1999.0066-782Xhttp://hdl.handle.net/11449/1126710.1590/S0066-782X1999000700004S0066-782X1999000700004S0066-782X1999000700004.pdf159097157630942002463913032413760000-0002-0648-876XSciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengArquivos Brasileiros de Cardiologia1.318info:eu-repo/semantics/openAccess2024-09-03T13:46:19Zoai:repositorio.unesp.br:11449/11267Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-03T13:46:19Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Influence of the elevation of the left ventricular diastolic pressure on the values of the first temporal derivative of the ventricular pressure (dP/dt)
title Influence of the elevation of the left ventricular diastolic pressure on the values of the first temporal derivative of the ventricular pressure (dP/dt)
spellingShingle Influence of the elevation of the left ventricular diastolic pressure on the values of the first temporal derivative of the ventricular pressure (dP/dt)
Okoshi, Katashi [UNESP]
Frank-Starling mechanism
dP/dt
ventricular function
title_short Influence of the elevation of the left ventricular diastolic pressure on the values of the first temporal derivative of the ventricular pressure (dP/dt)
title_full Influence of the elevation of the left ventricular diastolic pressure on the values of the first temporal derivative of the ventricular pressure (dP/dt)
title_fullStr Influence of the elevation of the left ventricular diastolic pressure on the values of the first temporal derivative of the ventricular pressure (dP/dt)
title_full_unstemmed Influence of the elevation of the left ventricular diastolic pressure on the values of the first temporal derivative of the ventricular pressure (dP/dt)
title_sort Influence of the elevation of the left ventricular diastolic pressure on the values of the first temporal derivative of the ventricular pressure (dP/dt)
author Okoshi, Katashi [UNESP]
author_facet Okoshi, Katashi [UNESP]
Fioretto, José Roberto [UNESP]
Bonatto, Rossano César [UNESP]
Tornero, Maria Teresinha Trovarelli [UNESP]
Tucci, Paulo José [UNESP]
author_role author
author2 Fioretto, José Roberto [UNESP]
Bonatto, Rossano César [UNESP]
Tornero, Maria Teresinha Trovarelli [UNESP]
Tucci, Paulo José [UNESP]
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Okoshi, Katashi [UNESP]
Fioretto, José Roberto [UNESP]
Bonatto, Rossano César [UNESP]
Tornero, Maria Teresinha Trovarelli [UNESP]
Tucci, Paulo José [UNESP]
dc.subject.por.fl_str_mv Frank-Starling mechanism
dP/dt
ventricular function
topic Frank-Starling mechanism
dP/dt
ventricular function
description PURPOSE: To assess the effects of the elevation of the left ventricular end-diastolic pressure (LVEDP) on the value of the 1st temporal derivative of the ventricular pressure (dP/dt). METHODS: Nineteen anesthetized dogs were studied. The dogs were mechanically ventilated and underwent thoracotomy with parasympathetic nervous system block. The LVEDP was controlled with the use of a perfusion circuit connected to the left atrium and adjusted to the height of a reservoir. The elevation of the LVEDP was achieved by a sudden increase in the height of a reservoir filled with blood. Continuous recordings of the electrocardiogram, the aortic and ventricular pressures and the dP/dt were performed. RESULTS: Elevation of the LVEDP did not result in any variation of the heart rate (167±16.0bpm, before the procedure; 167±15.5bpm, after the procedure). All the other variables assessed, including systolic blood pressure (128±18.3mmHg and 150±21.5mmHg), diastolic blood pressure (98±16.9mmHg and 115±19.8mmHg), LVEDP (5.5±2.49 and 9.3±3.60mmHg), and dP/dt (4,855 ± 1,082 mmHg/s and 5,149±1,242mmHg/s) showed significant increases following the expansion of the ventricular cavity. Although the elevation of the dP/dt was statistically significant, 6 dogs curiously showed a decrease in the values of dP/dt. CONCLUSION: Sudden elevation of the LVEDP resulted in increased values of dP/dt; however, in some dogs, this response was not uniform.
publishDate 1999
dc.date.none.fl_str_mv 1999-07-01
2014-05-20T13:32:57Z
2014-05-20T13:32:57Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0066-782X1999000700004
Arquivos Brasileiros de Cardiologia. Sociedade Brasileira de Cardiologia - SBC, v. 73, n. 1, p. 42-46, 1999.
0066-782X
http://hdl.handle.net/11449/11267
10.1590/S0066-782X1999000700004
S0066-782X1999000700004
S0066-782X1999000700004.pdf
1590971576309420
0246391303241376
0000-0002-0648-876X
url http://dx.doi.org/10.1590/S0066-782X1999000700004
http://hdl.handle.net/11449/11267
identifier_str_mv Arquivos Brasileiros de Cardiologia. Sociedade Brasileira de Cardiologia - SBC, v. 73, n. 1, p. 42-46, 1999.
0066-782X
10.1590/S0066-782X1999000700004
S0066-782X1999000700004
S0066-782X1999000700004.pdf
1590971576309420
0246391303241376
0000-0002-0648-876X
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Arquivos Brasileiros de Cardiologia
1.318
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 42-46
application/pdf
dc.publisher.none.fl_str_mv Sociedade Brasileira de Cardiologia (SBC)
publisher.none.fl_str_mv Sociedade Brasileira de Cardiologia (SBC)
dc.source.none.fl_str_mv SciELO
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv repositoriounesp@unesp.br
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