Influence of the elevation of the left ventricular diastolic pressure on the values of the first temporal derivative of the ventricular pressure (dP/dt)
Autor(a) principal: | |
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Data de Publicação: | 1999 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/S0066-782X1999000700004 http://hdl.handle.net/11449/11267 |
Resumo: | PURPOSE: To assess the effects of the elevation of the left ventricular end-diastolic pressure (LVEDP) on the value of the 1st temporal derivative of the ventricular pressure (dP/dt). METHODS: Nineteen anesthetized dogs were studied. The dogs were mechanically ventilated and underwent thoracotomy with parasympathetic nervous system block. The LVEDP was controlled with the use of a perfusion circuit connected to the left atrium and adjusted to the height of a reservoir. The elevation of the LVEDP was achieved by a sudden increase in the height of a reservoir filled with blood. Continuous recordings of the electrocardiogram, the aortic and ventricular pressures and the dP/dt were performed. RESULTS: Elevation of the LVEDP did not result in any variation of the heart rate (167±16.0bpm, before the procedure; 167±15.5bpm, after the procedure). All the other variables assessed, including systolic blood pressure (128±18.3mmHg and 150±21.5mmHg), diastolic blood pressure (98±16.9mmHg and 115±19.8mmHg), LVEDP (5.5±2.49 and 9.3±3.60mmHg), and dP/dt (4,855 ± 1,082 mmHg/s and 5,149±1,242mmHg/s) showed significant increases following the expansion of the ventricular cavity. Although the elevation of the dP/dt was statistically significant, 6 dogs curiously showed a decrease in the values of dP/dt. CONCLUSION: Sudden elevation of the LVEDP resulted in increased values of dP/dt; however, in some dogs, this response was not uniform. |
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Repositório Institucional da UNESP |
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Influence of the elevation of the left ventricular diastolic pressure on the values of the first temporal derivative of the ventricular pressure (dP/dt)Frank-Starling mechanismdP/dtventricular functionPURPOSE: To assess the effects of the elevation of the left ventricular end-diastolic pressure (LVEDP) on the value of the 1st temporal derivative of the ventricular pressure (dP/dt). METHODS: Nineteen anesthetized dogs were studied. The dogs were mechanically ventilated and underwent thoracotomy with parasympathetic nervous system block. The LVEDP was controlled with the use of a perfusion circuit connected to the left atrium and adjusted to the height of a reservoir. The elevation of the LVEDP was achieved by a sudden increase in the height of a reservoir filled with blood. Continuous recordings of the electrocardiogram, the aortic and ventricular pressures and the dP/dt were performed. RESULTS: Elevation of the LVEDP did not result in any variation of the heart rate (167±16.0bpm, before the procedure; 167±15.5bpm, after the procedure). All the other variables assessed, including systolic blood pressure (128±18.3mmHg and 150±21.5mmHg), diastolic blood pressure (98±16.9mmHg and 115±19.8mmHg), LVEDP (5.5±2.49 and 9.3±3.60mmHg), and dP/dt (4,855 ± 1,082 mmHg/s and 5,149±1,242mmHg/s) showed significant increases following the expansion of the ventricular cavity. Although the elevation of the dP/dt was statistically significant, 6 dogs curiously showed a decrease in the values of dP/dt. CONCLUSION: Sudden elevation of the LVEDP resulted in increased values of dP/dt; however, in some dogs, this response was not uniform.Universidade Estadual de São Paulo Faculdade de Medicina de BotucatuSociedade Brasileira de Cardiologia (SBC)Universidade Estadual Paulista (Unesp)Okoshi, Katashi [UNESP]Fioretto, José Roberto [UNESP]Bonatto, Rossano César [UNESP]Tornero, Maria Teresinha Trovarelli [UNESP]Tucci, Paulo José [UNESP]2014-05-20T13:32:57Z2014-05-20T13:32:57Z1999-07-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article42-46application/pdfhttp://dx.doi.org/10.1590/S0066-782X1999000700004Arquivos Brasileiros de Cardiologia. Sociedade Brasileira de Cardiologia - SBC, v. 73, n. 1, p. 42-46, 1999.0066-782Xhttp://hdl.handle.net/11449/1126710.1590/S0066-782X1999000700004S0066-782X1999000700004S0066-782X1999000700004.pdf159097157630942002463913032413760000-0002-0648-876XSciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengArquivos Brasileiros de Cardiologia1.318info:eu-repo/semantics/openAccess2024-09-03T13:46:19Zoai:repositorio.unesp.br:11449/11267Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-03T13:46:19Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Influence of the elevation of the left ventricular diastolic pressure on the values of the first temporal derivative of the ventricular pressure (dP/dt) |
title |
Influence of the elevation of the left ventricular diastolic pressure on the values of the first temporal derivative of the ventricular pressure (dP/dt) |
spellingShingle |
Influence of the elevation of the left ventricular diastolic pressure on the values of the first temporal derivative of the ventricular pressure (dP/dt) Okoshi, Katashi [UNESP] Frank-Starling mechanism dP/dt ventricular function |
title_short |
Influence of the elevation of the left ventricular diastolic pressure on the values of the first temporal derivative of the ventricular pressure (dP/dt) |
title_full |
Influence of the elevation of the left ventricular diastolic pressure on the values of the first temporal derivative of the ventricular pressure (dP/dt) |
title_fullStr |
Influence of the elevation of the left ventricular diastolic pressure on the values of the first temporal derivative of the ventricular pressure (dP/dt) |
title_full_unstemmed |
Influence of the elevation of the left ventricular diastolic pressure on the values of the first temporal derivative of the ventricular pressure (dP/dt) |
title_sort |
Influence of the elevation of the left ventricular diastolic pressure on the values of the first temporal derivative of the ventricular pressure (dP/dt) |
author |
Okoshi, Katashi [UNESP] |
author_facet |
Okoshi, Katashi [UNESP] Fioretto, José Roberto [UNESP] Bonatto, Rossano César [UNESP] Tornero, Maria Teresinha Trovarelli [UNESP] Tucci, Paulo José [UNESP] |
author_role |
author |
author2 |
Fioretto, José Roberto [UNESP] Bonatto, Rossano César [UNESP] Tornero, Maria Teresinha Trovarelli [UNESP] Tucci, Paulo José [UNESP] |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Okoshi, Katashi [UNESP] Fioretto, José Roberto [UNESP] Bonatto, Rossano César [UNESP] Tornero, Maria Teresinha Trovarelli [UNESP] Tucci, Paulo José [UNESP] |
dc.subject.por.fl_str_mv |
Frank-Starling mechanism dP/dt ventricular function |
topic |
Frank-Starling mechanism dP/dt ventricular function |
description |
PURPOSE: To assess the effects of the elevation of the left ventricular end-diastolic pressure (LVEDP) on the value of the 1st temporal derivative of the ventricular pressure (dP/dt). METHODS: Nineteen anesthetized dogs were studied. The dogs were mechanically ventilated and underwent thoracotomy with parasympathetic nervous system block. The LVEDP was controlled with the use of a perfusion circuit connected to the left atrium and adjusted to the height of a reservoir. The elevation of the LVEDP was achieved by a sudden increase in the height of a reservoir filled with blood. Continuous recordings of the electrocardiogram, the aortic and ventricular pressures and the dP/dt were performed. RESULTS: Elevation of the LVEDP did not result in any variation of the heart rate (167±16.0bpm, before the procedure; 167±15.5bpm, after the procedure). All the other variables assessed, including systolic blood pressure (128±18.3mmHg and 150±21.5mmHg), diastolic blood pressure (98±16.9mmHg and 115±19.8mmHg), LVEDP (5.5±2.49 and 9.3±3.60mmHg), and dP/dt (4,855 ± 1,082 mmHg/s and 5,149±1,242mmHg/s) showed significant increases following the expansion of the ventricular cavity. Although the elevation of the dP/dt was statistically significant, 6 dogs curiously showed a decrease in the values of dP/dt. CONCLUSION: Sudden elevation of the LVEDP resulted in increased values of dP/dt; however, in some dogs, this response was not uniform. |
publishDate |
1999 |
dc.date.none.fl_str_mv |
1999-07-01 2014-05-20T13:32:57Z 2014-05-20T13:32:57Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S0066-782X1999000700004 Arquivos Brasileiros de Cardiologia. Sociedade Brasileira de Cardiologia - SBC, v. 73, n. 1, p. 42-46, 1999. 0066-782X http://hdl.handle.net/11449/11267 10.1590/S0066-782X1999000700004 S0066-782X1999000700004 S0066-782X1999000700004.pdf 1590971576309420 0246391303241376 0000-0002-0648-876X |
url |
http://dx.doi.org/10.1590/S0066-782X1999000700004 http://hdl.handle.net/11449/11267 |
identifier_str_mv |
Arquivos Brasileiros de Cardiologia. Sociedade Brasileira de Cardiologia - SBC, v. 73, n. 1, p. 42-46, 1999. 0066-782X 10.1590/S0066-782X1999000700004 S0066-782X1999000700004 S0066-782X1999000700004.pdf 1590971576309420 0246391303241376 0000-0002-0648-876X |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Arquivos Brasileiros de Cardiologia 1.318 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
42-46 application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Cardiologia (SBC) |
publisher.none.fl_str_mv |
Sociedade Brasileira de Cardiologia (SBC) |
dc.source.none.fl_str_mv |
SciELO reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
repositoriounesp@unesp.br |
_version_ |
1810021363537149952 |