Field relevant doses of the fipronil affects gene expression in honey bees Apis mellifera
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
DOI: | 10.1007/s13592-022-00978-7 |
Texto Completo: | http://dx.doi.org/10.1007/s13592-022-00978-7 http://hdl.handle.net/11449/249007 |
Resumo: | We analyzed the changes in the gene expression of forage honey bees (Apis mellifera) exposed to fipronil field-relevant dose (2.5 ppb/bee) by 1 or 4 h. A reduction in the expression of nine genes was observed after 4 h of exposure, five of which are related to the digestive system: endoglucanase E-4, MSS11 transcription activator, inositol monophosphatase 2-X1 transcription variant, ATP-binding cassette G subfamily, and cuticular protein 28; one related to exoskeleton composition: cuticular protein 28; two related to vitamin E transport and antioxidant system: alpha-tocopherol transfer protein-like and transcript variant X3. LOC551765, LOC100578929, and LOC102656070 were downregulated; however, these genes have not yet been studied. The results indicate that the fipronil causes changes in the expression of genes related to physiological and morphological, metabolism, and behavior in A. mellifera honey bees. |
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Repositório Institucional da UNESP |
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spelling |
Field relevant doses of the fipronil affects gene expression in honey bees Apis melliferagene expressionhoney beespesticidesphysiological effectsWe analyzed the changes in the gene expression of forage honey bees (Apis mellifera) exposed to fipronil field-relevant dose (2.5 ppb/bee) by 1 or 4 h. A reduction in the expression of nine genes was observed after 4 h of exposure, five of which are related to the digestive system: endoglucanase E-4, MSS11 transcription activator, inositol monophosphatase 2-X1 transcription variant, ATP-binding cassette G subfamily, and cuticular protein 28; one related to exoskeleton composition: cuticular protein 28; two related to vitamin E transport and antioxidant system: alpha-tocopherol transfer protein-like and transcript variant X3. LOC551765, LOC100578929, and LOC102656070 were downregulated; however, these genes have not yet been studied. The results indicate that the fipronil causes changes in the expression of genes related to physiological and morphological, metabolism, and behavior in A. mellifera honey bees.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Center of Education Science and Technology in Rational Beekeeping (NECTAR) Department of Animal Production and Medicine Veterinary Preventive UNESP – Univ. Estadual PaulistaInstitute of Biotechnology - IBTEC UNESP – São Paulo State University, São PauloFaculdade de Medicina Veterinária e Zootecnia (FMVZ) Departamento de Produção Animal e Medicina Veterinária Preventiva Campus Botucatu - Distrito de Rubião Junior s/n, Caixa Postal 560, CEP: 18618-970Center of Education Science and Technology in Rational Beekeeping (NECTAR) Department of Animal Production and Medicine Veterinary Preventive UNESP – Univ. Estadual PaulistaInstitute of Biotechnology - IBTEC UNESP – São Paulo State University, São PauloFAPESP: 2020/10524-0Universidade Estadual Paulista (UNESP)Departamento de Produção Animal e Medicina Veterinária PreventivaAstolfi, Aline [UNESP]Kadri, Samir Moura [UNESP]de Castro Lippi, Isabella Cristina [UNESP]Mendes, Daniel Diego [UNESP]Alonso, Diego Peres [UNESP]Ribolla, Paulo Eduardo Martins [UNESP]de Oliveira Orsi, Ricardo [UNESP]2023-07-29T13:59:49Z2023-07-29T13:59:49Z2022-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1007/s13592-022-00978-7Apidologie, v. 53, n. 6, 2022.1297-96780044-8435http://hdl.handle.net/11449/24900710.1007/s13592-022-00978-72-s2.0-85142902207Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengApidologieinfo:eu-repo/semantics/openAccess2024-09-09T13:01:36Zoai:repositorio.unesp.br:11449/249007Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-09T13:01:36Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Field relevant doses of the fipronil affects gene expression in honey bees Apis mellifera |
title |
Field relevant doses of the fipronil affects gene expression in honey bees Apis mellifera |
spellingShingle |
Field relevant doses of the fipronil affects gene expression in honey bees Apis mellifera Field relevant doses of the fipronil affects gene expression in honey bees Apis mellifera Astolfi, Aline [UNESP] gene expression honey bees pesticides physiological effects Astolfi, Aline [UNESP] gene expression honey bees pesticides physiological effects |
title_short |
Field relevant doses of the fipronil affects gene expression in honey bees Apis mellifera |
title_full |
Field relevant doses of the fipronil affects gene expression in honey bees Apis mellifera |
title_fullStr |
Field relevant doses of the fipronil affects gene expression in honey bees Apis mellifera Field relevant doses of the fipronil affects gene expression in honey bees Apis mellifera |
title_full_unstemmed |
Field relevant doses of the fipronil affects gene expression in honey bees Apis mellifera Field relevant doses of the fipronil affects gene expression in honey bees Apis mellifera |
title_sort |
Field relevant doses of the fipronil affects gene expression in honey bees Apis mellifera |
author |
Astolfi, Aline [UNESP] |
author_facet |
Astolfi, Aline [UNESP] Astolfi, Aline [UNESP] Kadri, Samir Moura [UNESP] de Castro Lippi, Isabella Cristina [UNESP] Mendes, Daniel Diego [UNESP] Alonso, Diego Peres [UNESP] Ribolla, Paulo Eduardo Martins [UNESP] de Oliveira Orsi, Ricardo [UNESP] Kadri, Samir Moura [UNESP] de Castro Lippi, Isabella Cristina [UNESP] Mendes, Daniel Diego [UNESP] Alonso, Diego Peres [UNESP] Ribolla, Paulo Eduardo Martins [UNESP] de Oliveira Orsi, Ricardo [UNESP] |
author_role |
author |
author2 |
Kadri, Samir Moura [UNESP] de Castro Lippi, Isabella Cristina [UNESP] Mendes, Daniel Diego [UNESP] Alonso, Diego Peres [UNESP] Ribolla, Paulo Eduardo Martins [UNESP] de Oliveira Orsi, Ricardo [UNESP] |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) Departamento de Produção Animal e Medicina Veterinária Preventiva |
dc.contributor.author.fl_str_mv |
Astolfi, Aline [UNESP] Kadri, Samir Moura [UNESP] de Castro Lippi, Isabella Cristina [UNESP] Mendes, Daniel Diego [UNESP] Alonso, Diego Peres [UNESP] Ribolla, Paulo Eduardo Martins [UNESP] de Oliveira Orsi, Ricardo [UNESP] |
dc.subject.por.fl_str_mv |
gene expression honey bees pesticides physiological effects |
topic |
gene expression honey bees pesticides physiological effects |
description |
We analyzed the changes in the gene expression of forage honey bees (Apis mellifera) exposed to fipronil field-relevant dose (2.5 ppb/bee) by 1 or 4 h. A reduction in the expression of nine genes was observed after 4 h of exposure, five of which are related to the digestive system: endoglucanase E-4, MSS11 transcription activator, inositol monophosphatase 2-X1 transcription variant, ATP-binding cassette G subfamily, and cuticular protein 28; one related to exoskeleton composition: cuticular protein 28; two related to vitamin E transport and antioxidant system: alpha-tocopherol transfer protein-like and transcript variant X3. LOC551765, LOC100578929, and LOC102656070 were downregulated; however, these genes have not yet been studied. The results indicate that the fipronil causes changes in the expression of genes related to physiological and morphological, metabolism, and behavior in A. mellifera honey bees. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-12-01 2023-07-29T13:59:49Z 2023-07-29T13:59:49Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1007/s13592-022-00978-7 Apidologie, v. 53, n. 6, 2022. 1297-9678 0044-8435 http://hdl.handle.net/11449/249007 10.1007/s13592-022-00978-7 2-s2.0-85142902207 |
url |
http://dx.doi.org/10.1007/s13592-022-00978-7 http://hdl.handle.net/11449/249007 |
identifier_str_mv |
Apidologie, v. 53, n. 6, 2022. 1297-9678 0044-8435 10.1007/s13592-022-00978-7 2-s2.0-85142902207 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Apidologie |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
repositoriounesp@unesp.br |
_version_ |
1822183849079078912 |
dc.identifier.doi.none.fl_str_mv |
10.1007/s13592-022-00978-7 |