Field relevant doses of the fipronil affects gene expression in honey bees Apis mellifera

Detalhes bibliográficos
Autor(a) principal: Astolfi, Aline [UNESP]
Data de Publicação: 2022
Outros Autores: Kadri, Samir Moura [UNESP], de Castro Lippi, Isabella Cristina [UNESP], Mendes, Daniel Diego [UNESP], Alonso, Diego Peres [UNESP], Ribolla, Paulo Eduardo Martins [UNESP], de Oliveira Orsi, Ricardo [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
DOI: 10.1007/s13592-022-00978-7
Texto Completo: http://dx.doi.org/10.1007/s13592-022-00978-7
http://hdl.handle.net/11449/249007
Resumo: We analyzed the changes in the gene expression of forage honey bees (Apis mellifera) exposed to fipronil field-relevant dose (2.5 ppb/bee) by 1 or 4 h. A reduction in the expression of nine genes was observed after 4 h of exposure, five of which are related to the digestive system: endoglucanase E-4, MSS11 transcription activator, inositol monophosphatase 2-X1 transcription variant, ATP-binding cassette G subfamily, and cuticular protein 28; one related to exoskeleton composition: cuticular protein 28; two related to vitamin E transport and antioxidant system: alpha-tocopherol transfer protein-like and transcript variant X3. LOC551765, LOC100578929, and LOC102656070 were downregulated; however, these genes have not yet been studied. The results indicate that the fipronil causes changes in the expression of genes related to physiological and morphological, metabolism, and behavior in A. mellifera honey bees.
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spelling Field relevant doses of the fipronil affects gene expression in honey bees Apis melliferagene expressionhoney beespesticidesphysiological effectsWe analyzed the changes in the gene expression of forage honey bees (Apis mellifera) exposed to fipronil field-relevant dose (2.5 ppb/bee) by 1 or 4 h. A reduction in the expression of nine genes was observed after 4 h of exposure, five of which are related to the digestive system: endoglucanase E-4, MSS11 transcription activator, inositol monophosphatase 2-X1 transcription variant, ATP-binding cassette G subfamily, and cuticular protein 28; one related to exoskeleton composition: cuticular protein 28; two related to vitamin E transport and antioxidant system: alpha-tocopherol transfer protein-like and transcript variant X3. LOC551765, LOC100578929, and LOC102656070 were downregulated; however, these genes have not yet been studied. The results indicate that the fipronil causes changes in the expression of genes related to physiological and morphological, metabolism, and behavior in A. mellifera honey bees.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Center of Education Science and Technology in Rational Beekeeping (NECTAR) Department of Animal Production and Medicine Veterinary Preventive UNESP – Univ. Estadual PaulistaInstitute of Biotechnology - IBTEC UNESP – São Paulo State University, São PauloFaculdade de Medicina Veterinária e Zootecnia (FMVZ) Departamento de Produção Animal e Medicina Veterinária Preventiva Campus Botucatu - Distrito de Rubião Junior s/n, Caixa Postal 560, CEP: 18618-970Center of Education Science and Technology in Rational Beekeeping (NECTAR) Department of Animal Production and Medicine Veterinary Preventive UNESP – Univ. Estadual PaulistaInstitute of Biotechnology - IBTEC UNESP – São Paulo State University, São PauloFAPESP: 2020/10524-0Universidade Estadual Paulista (UNESP)Departamento de Produção Animal e Medicina Veterinária PreventivaAstolfi, Aline [UNESP]Kadri, Samir Moura [UNESP]de Castro Lippi, Isabella Cristina [UNESP]Mendes, Daniel Diego [UNESP]Alonso, Diego Peres [UNESP]Ribolla, Paulo Eduardo Martins [UNESP]de Oliveira Orsi, Ricardo [UNESP]2023-07-29T13:59:49Z2023-07-29T13:59:49Z2022-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1007/s13592-022-00978-7Apidologie, v. 53, n. 6, 2022.1297-96780044-8435http://hdl.handle.net/11449/24900710.1007/s13592-022-00978-72-s2.0-85142902207Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengApidologieinfo:eu-repo/semantics/openAccess2024-09-09T13:01:36Zoai:repositorio.unesp.br:11449/249007Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-09T13:01:36Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Field relevant doses of the fipronil affects gene expression in honey bees Apis mellifera
title Field relevant doses of the fipronil affects gene expression in honey bees Apis mellifera
spellingShingle Field relevant doses of the fipronil affects gene expression in honey bees Apis mellifera
Field relevant doses of the fipronil affects gene expression in honey bees Apis mellifera
Astolfi, Aline [UNESP]
gene expression
honey bees
pesticides
physiological effects
Astolfi, Aline [UNESP]
gene expression
honey bees
pesticides
physiological effects
title_short Field relevant doses of the fipronil affects gene expression in honey bees Apis mellifera
title_full Field relevant doses of the fipronil affects gene expression in honey bees Apis mellifera
title_fullStr Field relevant doses of the fipronil affects gene expression in honey bees Apis mellifera
Field relevant doses of the fipronil affects gene expression in honey bees Apis mellifera
title_full_unstemmed Field relevant doses of the fipronil affects gene expression in honey bees Apis mellifera
Field relevant doses of the fipronil affects gene expression in honey bees Apis mellifera
title_sort Field relevant doses of the fipronil affects gene expression in honey bees Apis mellifera
author Astolfi, Aline [UNESP]
author_facet Astolfi, Aline [UNESP]
Astolfi, Aline [UNESP]
Kadri, Samir Moura [UNESP]
de Castro Lippi, Isabella Cristina [UNESP]
Mendes, Daniel Diego [UNESP]
Alonso, Diego Peres [UNESP]
Ribolla, Paulo Eduardo Martins [UNESP]
de Oliveira Orsi, Ricardo [UNESP]
Kadri, Samir Moura [UNESP]
de Castro Lippi, Isabella Cristina [UNESP]
Mendes, Daniel Diego [UNESP]
Alonso, Diego Peres [UNESP]
Ribolla, Paulo Eduardo Martins [UNESP]
de Oliveira Orsi, Ricardo [UNESP]
author_role author
author2 Kadri, Samir Moura [UNESP]
de Castro Lippi, Isabella Cristina [UNESP]
Mendes, Daniel Diego [UNESP]
Alonso, Diego Peres [UNESP]
Ribolla, Paulo Eduardo Martins [UNESP]
de Oliveira Orsi, Ricardo [UNESP]
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (UNESP)
Departamento de Produção Animal e Medicina Veterinária Preventiva
dc.contributor.author.fl_str_mv Astolfi, Aline [UNESP]
Kadri, Samir Moura [UNESP]
de Castro Lippi, Isabella Cristina [UNESP]
Mendes, Daniel Diego [UNESP]
Alonso, Diego Peres [UNESP]
Ribolla, Paulo Eduardo Martins [UNESP]
de Oliveira Orsi, Ricardo [UNESP]
dc.subject.por.fl_str_mv gene expression
honey bees
pesticides
physiological effects
topic gene expression
honey bees
pesticides
physiological effects
description We analyzed the changes in the gene expression of forage honey bees (Apis mellifera) exposed to fipronil field-relevant dose (2.5 ppb/bee) by 1 or 4 h. A reduction in the expression of nine genes was observed after 4 h of exposure, five of which are related to the digestive system: endoglucanase E-4, MSS11 transcription activator, inositol monophosphatase 2-X1 transcription variant, ATP-binding cassette G subfamily, and cuticular protein 28; one related to exoskeleton composition: cuticular protein 28; two related to vitamin E transport and antioxidant system: alpha-tocopherol transfer protein-like and transcript variant X3. LOC551765, LOC100578929, and LOC102656070 were downregulated; however, these genes have not yet been studied. The results indicate that the fipronil causes changes in the expression of genes related to physiological and morphological, metabolism, and behavior in A. mellifera honey bees.
publishDate 2022
dc.date.none.fl_str_mv 2022-12-01
2023-07-29T13:59:49Z
2023-07-29T13:59:49Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1007/s13592-022-00978-7
Apidologie, v. 53, n. 6, 2022.
1297-9678
0044-8435
http://hdl.handle.net/11449/249007
10.1007/s13592-022-00978-7
2-s2.0-85142902207
url http://dx.doi.org/10.1007/s13592-022-00978-7
http://hdl.handle.net/11449/249007
identifier_str_mv Apidologie, v. 53, n. 6, 2022.
1297-9678
0044-8435
10.1007/s13592-022-00978-7
2-s2.0-85142902207
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Apidologie
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv repositoriounesp@unesp.br
_version_ 1822183849079078912
dc.identifier.doi.none.fl_str_mv 10.1007/s13592-022-00978-7