Enhanced bioactive properties of biodentine™ modified with bioactive glass nanoparticles
Autor(a) principal: | |
---|---|
Data de Publicação: | 2017 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/1678-77572016-0209 http://hdl.handle.net/11449/169636 |
Resumo: | Objective To prepare nanocomposite cements based on the incorporation of bioactive glass nanoparticles (nBGs) into BiodentineTM (BD, Septodent, Saint-Maur-des-Fosses Cedex, France) and to assess their bioactive properties. Material and Methods nBGs were synthesised by the sol-gel method. BD nanocomposites (nBG/BD) were prepared with 1 and 2% nBGs by weight; unmodified BD and GC Fuji IX (GIC, GC Corporation, Tokyo, Japan) were used as references. The in vitro ability of the materials to induce apatite formation was assessed in SBF by X-ray diffraction (XRD), attenuated total reflectance with Fourier transform infrared spectroscopy (ATR-FTIR), and scanning electron microscopy (SEM) with energy dispersive X-ray (EDX) analysis. BD and nBG/BD were also applied to dentine discs for seven days; the morphology and elemental composition of the dentine-cement interface were analysed using SEM-EDX. Results One and two percent nBG/BD composites accelerated apatite formation on the disc surface after short-term immersion in SBF. Apatite was detected on the nBG/BD nanocomposites after three days, compared with seven days for unmodified BD. No apatite formation was detected on the GIC surface. nBG/BD formed a wider interfacial area with dentine than BD, showing blockage of dentine tubules and Si incorporation, suggesting intratubular precipitation. Conclusions The incorporation of nBGs into BD improves its in vitro bioactivity, accelerating the formation of a crystalline apatite layer on its surface after immersion in SBF. Compared with unmodified BD, nBG/BD showed a wider interfacial area with greater Si incorporation and intratubular precipitation of deposits when immersed in SBF. |
id |
UNSP_711c9c37325fc0034e2c15900df3b721 |
---|---|
oai_identifier_str |
oai:repositorio.unesp.br:11449/169636 |
network_acronym_str |
UNSP |
network_name_str |
Repositório Institucional da UNESP |
repository_id_str |
2946 |
spelling |
Enhanced bioactive properties of biodentine™ modified with bioactive glass nanoparticlesApatite-forming abilityBioactive glassBioactivityBiodentineNanocompositesObjective To prepare nanocomposite cements based on the incorporation of bioactive glass nanoparticles (nBGs) into BiodentineTM (BD, Septodent, Saint-Maur-des-Fosses Cedex, France) and to assess their bioactive properties. Material and Methods nBGs were synthesised by the sol-gel method. BD nanocomposites (nBG/BD) were prepared with 1 and 2% nBGs by weight; unmodified BD and GC Fuji IX (GIC, GC Corporation, Tokyo, Japan) were used as references. The in vitro ability of the materials to induce apatite formation was assessed in SBF by X-ray diffraction (XRD), attenuated total reflectance with Fourier transform infrared spectroscopy (ATR-FTIR), and scanning electron microscopy (SEM) with energy dispersive X-ray (EDX) analysis. BD and nBG/BD were also applied to dentine discs for seven days; the morphology and elemental composition of the dentine-cement interface were analysed using SEM-EDX. Results One and two percent nBG/BD composites accelerated apatite formation on the disc surface after short-term immersion in SBF. Apatite was detected on the nBG/BD nanocomposites after three days, compared with seven days for unmodified BD. No apatite formation was detected on the GIC surface. nBG/BD formed a wider interfacial area with dentine than BD, showing blockage of dentine tubules and Si incorporation, suggesting intratubular precipitation. Conclusions The incorporation of nBGs into BD improves its in vitro bioactivity, accelerating the formation of a crystalline apatite layer on its surface after immersion in SBF. Compared with unmodified BD, nBG/BD showed a wider interfacial area with greater Si incorporation and intratubular precipitation of deposits when immersed in SBF.Universidad de Chile Facultad de Odontología Departamento de Odontología RestauradoraUniversidade Estadual Paulista - UNESP Faculdade de Odontologia Departmento de Odontologia RestauradoraUniversidad de Chile Facultad de Odontología Instituto de Investigación en Ciencias Odontológicas Laboratorio de NanobiomaterialesUniversidade Estadual Paulista - UNESP Faculdade de Odontologia Departmento de Odontologia RestauradoraFacultad de OdontologíaUniversidade Estadual Paulista (Unesp)Laboratorio de NanobiomaterialesCorral Nuñez, Camila [UNESP]Covarrubias, CristianFernandez, EduardoOliveira Junior, Osmir Batista de [UNESP]2018-12-11T16:46:57Z2018-12-11T16:46:57Z2017-03-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article177-185application/pdfhttp://dx.doi.org/10.1590/1678-77572016-0209Journal of Applied Oral Science, v. 25, n. 2, p. 177-185, 2017.1678-77651678-7757http://hdl.handle.net/11449/16963610.1590/1678-77572016-0209S1678-775720170002001772-s2.0-85017536248S1678-77572017000200177.pdf01702412112196160000-0002-2153-9887Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Applied Oral Science0,645info:eu-repo/semantics/openAccess2024-01-18T06:27:26Zoai:repositorio.unesp.br:11449/169636Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T23:21:47.357112Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Enhanced bioactive properties of biodentine™ modified with bioactive glass nanoparticles |
title |
Enhanced bioactive properties of biodentine™ modified with bioactive glass nanoparticles |
spellingShingle |
Enhanced bioactive properties of biodentine™ modified with bioactive glass nanoparticles Corral Nuñez, Camila [UNESP] Apatite-forming ability Bioactive glass Bioactivity Biodentine Nanocomposites |
title_short |
Enhanced bioactive properties of biodentine™ modified with bioactive glass nanoparticles |
title_full |
Enhanced bioactive properties of biodentine™ modified with bioactive glass nanoparticles |
title_fullStr |
Enhanced bioactive properties of biodentine™ modified with bioactive glass nanoparticles |
title_full_unstemmed |
Enhanced bioactive properties of biodentine™ modified with bioactive glass nanoparticles |
title_sort |
Enhanced bioactive properties of biodentine™ modified with bioactive glass nanoparticles |
author |
Corral Nuñez, Camila [UNESP] |
author_facet |
Corral Nuñez, Camila [UNESP] Covarrubias, Cristian Fernandez, Eduardo Oliveira Junior, Osmir Batista de [UNESP] |
author_role |
author |
author2 |
Covarrubias, Cristian Fernandez, Eduardo Oliveira Junior, Osmir Batista de [UNESP] |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Facultad de Odontología Universidade Estadual Paulista (Unesp) Laboratorio de Nanobiomateriales |
dc.contributor.author.fl_str_mv |
Corral Nuñez, Camila [UNESP] Covarrubias, Cristian Fernandez, Eduardo Oliveira Junior, Osmir Batista de [UNESP] |
dc.subject.por.fl_str_mv |
Apatite-forming ability Bioactive glass Bioactivity Biodentine Nanocomposites |
topic |
Apatite-forming ability Bioactive glass Bioactivity Biodentine Nanocomposites |
description |
Objective To prepare nanocomposite cements based on the incorporation of bioactive glass nanoparticles (nBGs) into BiodentineTM (BD, Septodent, Saint-Maur-des-Fosses Cedex, France) and to assess their bioactive properties. Material and Methods nBGs were synthesised by the sol-gel method. BD nanocomposites (nBG/BD) were prepared with 1 and 2% nBGs by weight; unmodified BD and GC Fuji IX (GIC, GC Corporation, Tokyo, Japan) were used as references. The in vitro ability of the materials to induce apatite formation was assessed in SBF by X-ray diffraction (XRD), attenuated total reflectance with Fourier transform infrared spectroscopy (ATR-FTIR), and scanning electron microscopy (SEM) with energy dispersive X-ray (EDX) analysis. BD and nBG/BD were also applied to dentine discs for seven days; the morphology and elemental composition of the dentine-cement interface were analysed using SEM-EDX. Results One and two percent nBG/BD composites accelerated apatite formation on the disc surface after short-term immersion in SBF. Apatite was detected on the nBG/BD nanocomposites after three days, compared with seven days for unmodified BD. No apatite formation was detected on the GIC surface. nBG/BD formed a wider interfacial area with dentine than BD, showing blockage of dentine tubules and Si incorporation, suggesting intratubular precipitation. Conclusions The incorporation of nBGs into BD improves its in vitro bioactivity, accelerating the formation of a crystalline apatite layer on its surface after immersion in SBF. Compared with unmodified BD, nBG/BD showed a wider interfacial area with greater Si incorporation and intratubular precipitation of deposits when immersed in SBF. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-03-01 2018-12-11T16:46:57Z 2018-12-11T16:46:57Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/1678-77572016-0209 Journal of Applied Oral Science, v. 25, n. 2, p. 177-185, 2017. 1678-7765 1678-7757 http://hdl.handle.net/11449/169636 10.1590/1678-77572016-0209 S1678-77572017000200177 2-s2.0-85017536248 S1678-77572017000200177.pdf 0170241211219616 0000-0002-2153-9887 |
url |
http://dx.doi.org/10.1590/1678-77572016-0209 http://hdl.handle.net/11449/169636 |
identifier_str_mv |
Journal of Applied Oral Science, v. 25, n. 2, p. 177-185, 2017. 1678-7765 1678-7757 10.1590/1678-77572016-0209 S1678-77572017000200177 2-s2.0-85017536248 S1678-77572017000200177.pdf 0170241211219616 0000-0002-2153-9887 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Applied Oral Science 0,645 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
177-185 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129510326927360 |