Size and position of the reproductive tract impacts fertility outcomes and pregnancy losses in lactating dairy cows

Detalhes bibliográficos
Autor(a) principal: Madureira, A. M. L.
Data de Publicação: 2020
Outros Autores: Poole, R. K., Burnett, T. A., Guida, T. G. [UNESP], Edwards, J. L., Schrick, F. N., Vasconcelos, J. L. M. [UNESP], Cerri, R. L. A., Pohler, K. G.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1016/j.theriogenology.2020.08.022
http://hdl.handle.net/11449/209680
Resumo: There are multiple factors that contribute to reduced fertility in lactating dairy cows. Recently, a reproductive tract size and position score (SPS) system was developed as a management tool to identify dairy cows with decreased fertility. The aim of this study was to evaluate the association between the SPS on fertility outcomes such as ovulation failure, pregnancy per artificial insemination (P/AI), concentration of pregnancy-associated glycoproteins (PAGs), and pregnancy loss in lactating dairy cows. Primiparous and multiparous lactating Holstein cows (n = 869) were enrolled at two locations. Location 1 (Loc. 1) in Minas Gerais, Brazil (n = 613) and location 2 (Loc. 2) in Agassiz, British Columbia, Canada (n = 256). At the time of AI (d 0), cows were classified as SPS (small [SPS1], medium [SPS2], or large [SPS3] sized reproductive tract) and ovulation failure was determined at 48 h and 7 d post-AI via ultrasonography (Loc. 2 only). Blood samples were collected on d 24 and 31 of gestation for quantification of PAGs and pregnancy diagnosis was performed via ultrasonography at d 31 and 60 post-AI (Loc. 1) and at d 31 +/- 3 and 60 +/- 3 post-AI (Loc. 2). Cows diagnosed pregnant at d 31 post-AI but not pregnant at d 60 were defined to have undergone late embryonic pregnancy loss. Parity was found to impact SPS (P < 0.01), as primiparous cows had a higher frequency of SPS1 and lower frequency of SPS3 when compared with multiparous cows (SPS1: 42.6 vs. 15.0%; SPS3: 7.0 vs. 22.0%, respectively). Cows classified as SPS3 had greater ovulation failure at 48 h (P = 0.04) and 7 d post-AI (P = 0.05). Cows classified as SPS1 had greater P/AI when compared to SPS2 and SPS3 (45.9 +/- 3.3 vs. 37.4 +/- 2.6 and 29.1 +/- 3.5%, respectively; P = 0.004). There was no interaction between parity and SPS on P/AI. Pregnancy loss between 31 and 60 d post-AI was increased in cows classified as SPS3 compared to SPS2 and SPS1 (24.3 +/- 0.05 vs. 11.6 +/- 0.02 and 9.4 +/- 0.02%, respectively; P = 0.04). Cows classified as SPS1 and SPS2 had greater concentrations of PAGs at 31 d post-AI when compared to SPS3 at both Loc.1 (P < 0.01) and Loc. 2 (P < 0.01). There was no interaction between SPS and pregnancy loss on PAGs at 24 and 31 d postAI for either Loc. 1 (P = 0.75 and P = 0.76, respectively) or Loc. 2 (P = 0.61 and P = 0.81, respectively). In conclusion, cows that were classified as SPS3 had greater ovulation failure, reduced P/AI, similar concentrations of PAG on d 24, but decreased on d 31, and a greater incidence of pregnancy loss. Thus, size and position of the reproductive tract is associated with fertility and this scoring system could be used to make reproductive management decisions on dairy operations. (C) 2020 Elsevier Inc. All rights reserved.
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spelling Size and position of the reproductive tract impacts fertility outcomes and pregnancy losses in lactating dairy cowsDairy cattleReproductive tract size and position scoreFertilityPregnancy lossThere are multiple factors that contribute to reduced fertility in lactating dairy cows. Recently, a reproductive tract size and position score (SPS) system was developed as a management tool to identify dairy cows with decreased fertility. The aim of this study was to evaluate the association between the SPS on fertility outcomes such as ovulation failure, pregnancy per artificial insemination (P/AI), concentration of pregnancy-associated glycoproteins (PAGs), and pregnancy loss in lactating dairy cows. Primiparous and multiparous lactating Holstein cows (n = 869) were enrolled at two locations. Location 1 (Loc. 1) in Minas Gerais, Brazil (n = 613) and location 2 (Loc. 2) in Agassiz, British Columbia, Canada (n = 256). At the time of AI (d 0), cows were classified as SPS (small [SPS1], medium [SPS2], or large [SPS3] sized reproductive tract) and ovulation failure was determined at 48 h and 7 d post-AI via ultrasonography (Loc. 2 only). Blood samples were collected on d 24 and 31 of gestation for quantification of PAGs and pregnancy diagnosis was performed via ultrasonography at d 31 and 60 post-AI (Loc. 1) and at d 31 +/- 3 and 60 +/- 3 post-AI (Loc. 2). Cows diagnosed pregnant at d 31 post-AI but not pregnant at d 60 were defined to have undergone late embryonic pregnancy loss. Parity was found to impact SPS (P < 0.01), as primiparous cows had a higher frequency of SPS1 and lower frequency of SPS3 when compared with multiparous cows (SPS1: 42.6 vs. 15.0%; SPS3: 7.0 vs. 22.0%, respectively). Cows classified as SPS3 had greater ovulation failure at 48 h (P = 0.04) and 7 d post-AI (P = 0.05). Cows classified as SPS1 had greater P/AI when compared to SPS2 and SPS3 (45.9 +/- 3.3 vs. 37.4 +/- 2.6 and 29.1 +/- 3.5%, respectively; P = 0.004). There was no interaction between parity and SPS on P/AI. Pregnancy loss between 31 and 60 d post-AI was increased in cows classified as SPS3 compared to SPS2 and SPS1 (24.3 +/- 0.05 vs. 11.6 +/- 0.02 and 9.4 +/- 0.02%, respectively; P = 0.04). Cows classified as SPS1 and SPS2 had greater concentrations of PAGs at 31 d post-AI when compared to SPS3 at both Loc.1 (P < 0.01) and Loc. 2 (P < 0.01). There was no interaction between SPS and pregnancy loss on PAGs at 24 and 31 d postAI for either Loc. 1 (P = 0.75 and P = 0.76, respectively) or Loc. 2 (P = 0.61 and P = 0.81, respectively). In conclusion, cows that were classified as SPS3 had greater ovulation failure, reduced P/AI, similar concentrations of PAG on d 24, but decreased on d 31, and a greater incidence of pregnancy loss. Thus, size and position of the reproductive tract is associated with fertility and this scoring system could be used to make reproductive management decisions on dairy operations. (C) 2020 Elsevier Inc. All rights reserved.Dairy Research Cluster Initiative II (Dairy Farmers of Canada)Dairy Research Cluster Initiative II (Agriculture and Agri-Food Canada)Dairy Research Cluster Initiative II (Canadian Dairy Network)Dairy Research Cluster Initiative II (Canadian Dairy Commission; Ottawa, Canada)Natural Sciences and Engineering Research Council, Discovery Grant (Ottawa, Canada)USDA-NIFA Hatch/Multistate ProjectUniv British Columbia, Fac Land & Food Syst, Appl Anim Biol, Vancouver, BC V6T 1Z4, CanadaSao Paulo State Univ, Dept Anim Prod, BR-18168000 Botucatu, SP, BrazilUniv Tennessee, Dept Anim Sci, Knoxville, TN 37996 USATexas A&M Univ, Dept Anim Sci, Pregnancy & Dev Programming Area Excellence, College Stn, TX 77843 USASao Paulo State Univ, Dept Anim Prod, BR-18168000 Botucatu, SP, BrazilUSDA-NIFA Hatch/Multistate Project: W3112-TEX07702Elsevier B.V.Univ British ColumbiaUniversidade Estadual Paulista (Unesp)Univ TennesseeTexas A&M UnivMadureira, A. M. L.Poole, R. K.Burnett, T. A.Guida, T. G. [UNESP]Edwards, J. L.Schrick, F. N.Vasconcelos, J. L. M. [UNESP]Cerri, R. L. A.Pohler, K. G.2021-06-25T12:25:49Z2021-06-25T12:25:49Z2020-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article66-74http://dx.doi.org/10.1016/j.theriogenology.2020.08.022Theriogenology. New York: Elsevier Science Inc, v. 158, p. 66-74, 2020.0093-691Xhttp://hdl.handle.net/11449/20968010.1016/j.theriogenology.2020.08.022WOS:000591658500009Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengTheriogenologyinfo:eu-repo/semantics/openAccess2024-09-09T13:01:51Zoai:repositorio.unesp.br:11449/209680Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-09T13:01:51Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Size and position of the reproductive tract impacts fertility outcomes and pregnancy losses in lactating dairy cows
title Size and position of the reproductive tract impacts fertility outcomes and pregnancy losses in lactating dairy cows
spellingShingle Size and position of the reproductive tract impacts fertility outcomes and pregnancy losses in lactating dairy cows
Madureira, A. M. L.
Dairy cattle
Reproductive tract size and position score
Fertility
Pregnancy loss
title_short Size and position of the reproductive tract impacts fertility outcomes and pregnancy losses in lactating dairy cows
title_full Size and position of the reproductive tract impacts fertility outcomes and pregnancy losses in lactating dairy cows
title_fullStr Size and position of the reproductive tract impacts fertility outcomes and pregnancy losses in lactating dairy cows
title_full_unstemmed Size and position of the reproductive tract impacts fertility outcomes and pregnancy losses in lactating dairy cows
title_sort Size and position of the reproductive tract impacts fertility outcomes and pregnancy losses in lactating dairy cows
author Madureira, A. M. L.
author_facet Madureira, A. M. L.
Poole, R. K.
Burnett, T. A.
Guida, T. G. [UNESP]
Edwards, J. L.
Schrick, F. N.
Vasconcelos, J. L. M. [UNESP]
Cerri, R. L. A.
Pohler, K. G.
author_role author
author2 Poole, R. K.
Burnett, T. A.
Guida, T. G. [UNESP]
Edwards, J. L.
Schrick, F. N.
Vasconcelos, J. L. M. [UNESP]
Cerri, R. L. A.
Pohler, K. G.
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Univ British Columbia
Universidade Estadual Paulista (Unesp)
Univ Tennessee
Texas A&M Univ
dc.contributor.author.fl_str_mv Madureira, A. M. L.
Poole, R. K.
Burnett, T. A.
Guida, T. G. [UNESP]
Edwards, J. L.
Schrick, F. N.
Vasconcelos, J. L. M. [UNESP]
Cerri, R. L. A.
Pohler, K. G.
dc.subject.por.fl_str_mv Dairy cattle
Reproductive tract size and position score
Fertility
Pregnancy loss
topic Dairy cattle
Reproductive tract size and position score
Fertility
Pregnancy loss
description There are multiple factors that contribute to reduced fertility in lactating dairy cows. Recently, a reproductive tract size and position score (SPS) system was developed as a management tool to identify dairy cows with decreased fertility. The aim of this study was to evaluate the association between the SPS on fertility outcomes such as ovulation failure, pregnancy per artificial insemination (P/AI), concentration of pregnancy-associated glycoproteins (PAGs), and pregnancy loss in lactating dairy cows. Primiparous and multiparous lactating Holstein cows (n = 869) were enrolled at two locations. Location 1 (Loc. 1) in Minas Gerais, Brazil (n = 613) and location 2 (Loc. 2) in Agassiz, British Columbia, Canada (n = 256). At the time of AI (d 0), cows were classified as SPS (small [SPS1], medium [SPS2], or large [SPS3] sized reproductive tract) and ovulation failure was determined at 48 h and 7 d post-AI via ultrasonography (Loc. 2 only). Blood samples were collected on d 24 and 31 of gestation for quantification of PAGs and pregnancy diagnosis was performed via ultrasonography at d 31 and 60 post-AI (Loc. 1) and at d 31 +/- 3 and 60 +/- 3 post-AI (Loc. 2). Cows diagnosed pregnant at d 31 post-AI but not pregnant at d 60 were defined to have undergone late embryonic pregnancy loss. Parity was found to impact SPS (P < 0.01), as primiparous cows had a higher frequency of SPS1 and lower frequency of SPS3 when compared with multiparous cows (SPS1: 42.6 vs. 15.0%; SPS3: 7.0 vs. 22.0%, respectively). Cows classified as SPS3 had greater ovulation failure at 48 h (P = 0.04) and 7 d post-AI (P = 0.05). Cows classified as SPS1 had greater P/AI when compared to SPS2 and SPS3 (45.9 +/- 3.3 vs. 37.4 +/- 2.6 and 29.1 +/- 3.5%, respectively; P = 0.004). There was no interaction between parity and SPS on P/AI. Pregnancy loss between 31 and 60 d post-AI was increased in cows classified as SPS3 compared to SPS2 and SPS1 (24.3 +/- 0.05 vs. 11.6 +/- 0.02 and 9.4 +/- 0.02%, respectively; P = 0.04). Cows classified as SPS1 and SPS2 had greater concentrations of PAGs at 31 d post-AI when compared to SPS3 at both Loc.1 (P < 0.01) and Loc. 2 (P < 0.01). There was no interaction between SPS and pregnancy loss on PAGs at 24 and 31 d postAI for either Loc. 1 (P = 0.75 and P = 0.76, respectively) or Loc. 2 (P = 0.61 and P = 0.81, respectively). In conclusion, cows that were classified as SPS3 had greater ovulation failure, reduced P/AI, similar concentrations of PAG on d 24, but decreased on d 31, and a greater incidence of pregnancy loss. Thus, size and position of the reproductive tract is associated with fertility and this scoring system could be used to make reproductive management decisions on dairy operations. (C) 2020 Elsevier Inc. All rights reserved.
publishDate 2020
dc.date.none.fl_str_mv 2020-12-01
2021-06-25T12:25:49Z
2021-06-25T12:25:49Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/j.theriogenology.2020.08.022
Theriogenology. New York: Elsevier Science Inc, v. 158, p. 66-74, 2020.
0093-691X
http://hdl.handle.net/11449/209680
10.1016/j.theriogenology.2020.08.022
WOS:000591658500009
url http://dx.doi.org/10.1016/j.theriogenology.2020.08.022
http://hdl.handle.net/11449/209680
identifier_str_mv Theriogenology. New York: Elsevier Science Inc, v. 158, p. 66-74, 2020.
0093-691X
10.1016/j.theriogenology.2020.08.022
WOS:000591658500009
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Theriogenology
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 66-74
dc.publisher.none.fl_str_mv Elsevier B.V.
publisher.none.fl_str_mv Elsevier B.V.
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv repositoriounesp@unesp.br
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