Periodontitis Is Associated With Risk of Conventional Stent Restenosis: Pilot Case-Control Study
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.3389/fdmed.2021.673626 http://hdl.handle.net/11449/247414 |
Resumo: | Objectives: Percutaneous coronary angioplasty with stent implantation has been established as the main form of treatment of atherosclerosis. However, 16 to 44% of patients may evolve with stent restenosis. Periodontitis is an inflammatory condition associated with bacterial infection, that may lead to periodontal tissue destruction and tooth loss. This study aimed to evaluate the association between stent restenosis and periodontitis. Materials and Methods: Coronary angiography exams presenting stent imaging with and without restenosis were analyzed. Patients meeting the inclusion and exclusion criteria were selected and allocated in 2 groups: case (restenosis) and control (without restenosis). We evaluated if systemic and periodontal variables were predictors of restenosis (primary outcome) using a multivariable stepwise logistic regression. Additionally, we compared clinical and periodontal conditions between the control and case groups (secondary outcomes) using Chi-square test and ANOVA test. Results: Data from 49 patients (case n = 15; control n = 34) were analyzed. The results showed that stages III and IV periodontitis and lack of physical activity were significant predictors of stent restenosis (OR 5.82 and 5.98, respectively). Comparisons regarding the diagnosis of periodontal conditions between control and case groups did not present significant differences in the incidence of periodontitis and alveolar bone loss. Conclusion: Stages III and IV periodontitis increased the incidence of stent restenosis. These findings suggest that advanced stages of periodontal disease might lead to the occurrence of negative outcomes after coronary angioplasty with stent placement. |
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Periodontitis Is Associated With Risk of Conventional Stent Restenosis: Pilot Case-Control Studyatherosclerosiscardiovascular diseaseinflammationperiodontitisstent restenosisObjectives: Percutaneous coronary angioplasty with stent implantation has been established as the main form of treatment of atherosclerosis. However, 16 to 44% of patients may evolve with stent restenosis. Periodontitis is an inflammatory condition associated with bacterial infection, that may lead to periodontal tissue destruction and tooth loss. This study aimed to evaluate the association between stent restenosis and periodontitis. Materials and Methods: Coronary angiography exams presenting stent imaging with and without restenosis were analyzed. Patients meeting the inclusion and exclusion criteria were selected and allocated in 2 groups: case (restenosis) and control (without restenosis). We evaluated if systemic and periodontal variables were predictors of restenosis (primary outcome) using a multivariable stepwise logistic regression. Additionally, we compared clinical and periodontal conditions between the control and case groups (secondary outcomes) using Chi-square test and ANOVA test. Results: Data from 49 patients (case n = 15; control n = 34) were analyzed. The results showed that stages III and IV periodontitis and lack of physical activity were significant predictors of stent restenosis (OR 5.82 and 5.98, respectively). Comparisons regarding the diagnosis of periodontal conditions between control and case groups did not present significant differences in the incidence of periodontitis and alveolar bone loss. Conclusion: Stages III and IV periodontitis increased the incidence of stent restenosis. These findings suggest that advanced stages of periodontal disease might lead to the occurrence of negative outcomes after coronary angioplasty with stent placement.Division of Periodontics Institute of Science and Technology UNESP - São Paulo State UniversityDental Research Division Guarulhos UniversityDivision of Periodontics Institute of Science and Technology UNESP - São Paulo State UniversityUniversidade Estadual Paulista (UNESP)Guarulhos UniversityOsugue, Raphael [UNESP]Castro dos Santos, Nidia C. [UNESP]Araujo, Cassia F. [UNESP]de Almeida, Flavio X.Feres, MagdaSantamaria, Mauro P. [UNESP]2023-07-29T13:15:29Z2023-07-29T13:15:29Z2021-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.3389/fdmed.2021.673626Frontiers in Dental Medicine, v. 2.2673-4915http://hdl.handle.net/11449/24741410.3389/fdmed.2021.6736262-s2.0-85159903318Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengFrontiers in Dental Medicineinfo:eu-repo/semantics/openAccess2023-07-29T13:15:29Zoai:repositorio.unesp.br:11449/247414Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-07-29T13:15:29Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Periodontitis Is Associated With Risk of Conventional Stent Restenosis: Pilot Case-Control Study |
title |
Periodontitis Is Associated With Risk of Conventional Stent Restenosis: Pilot Case-Control Study |
spellingShingle |
Periodontitis Is Associated With Risk of Conventional Stent Restenosis: Pilot Case-Control Study Osugue, Raphael [UNESP] atherosclerosis cardiovascular disease inflammation periodontitis stent restenosis |
title_short |
Periodontitis Is Associated With Risk of Conventional Stent Restenosis: Pilot Case-Control Study |
title_full |
Periodontitis Is Associated With Risk of Conventional Stent Restenosis: Pilot Case-Control Study |
title_fullStr |
Periodontitis Is Associated With Risk of Conventional Stent Restenosis: Pilot Case-Control Study |
title_full_unstemmed |
Periodontitis Is Associated With Risk of Conventional Stent Restenosis: Pilot Case-Control Study |
title_sort |
Periodontitis Is Associated With Risk of Conventional Stent Restenosis: Pilot Case-Control Study |
author |
Osugue, Raphael [UNESP] |
author_facet |
Osugue, Raphael [UNESP] Castro dos Santos, Nidia C. [UNESP] Araujo, Cassia F. [UNESP] de Almeida, Flavio X. Feres, Magda Santamaria, Mauro P. [UNESP] |
author_role |
author |
author2 |
Castro dos Santos, Nidia C. [UNESP] Araujo, Cassia F. [UNESP] de Almeida, Flavio X. Feres, Magda Santamaria, Mauro P. [UNESP] |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) Guarulhos University |
dc.contributor.author.fl_str_mv |
Osugue, Raphael [UNESP] Castro dos Santos, Nidia C. [UNESP] Araujo, Cassia F. [UNESP] de Almeida, Flavio X. Feres, Magda Santamaria, Mauro P. [UNESP] |
dc.subject.por.fl_str_mv |
atherosclerosis cardiovascular disease inflammation periodontitis stent restenosis |
topic |
atherosclerosis cardiovascular disease inflammation periodontitis stent restenosis |
description |
Objectives: Percutaneous coronary angioplasty with stent implantation has been established as the main form of treatment of atherosclerosis. However, 16 to 44% of patients may evolve with stent restenosis. Periodontitis is an inflammatory condition associated with bacterial infection, that may lead to periodontal tissue destruction and tooth loss. This study aimed to evaluate the association between stent restenosis and periodontitis. Materials and Methods: Coronary angiography exams presenting stent imaging with and without restenosis were analyzed. Patients meeting the inclusion and exclusion criteria were selected and allocated in 2 groups: case (restenosis) and control (without restenosis). We evaluated if systemic and periodontal variables were predictors of restenosis (primary outcome) using a multivariable stepwise logistic regression. Additionally, we compared clinical and periodontal conditions between the control and case groups (secondary outcomes) using Chi-square test and ANOVA test. Results: Data from 49 patients (case n = 15; control n = 34) were analyzed. The results showed that stages III and IV periodontitis and lack of physical activity were significant predictors of stent restenosis (OR 5.82 and 5.98, respectively). Comparisons regarding the diagnosis of periodontal conditions between control and case groups did not present significant differences in the incidence of periodontitis and alveolar bone loss. Conclusion: Stages III and IV periodontitis increased the incidence of stent restenosis. These findings suggest that advanced stages of periodontal disease might lead to the occurrence of negative outcomes after coronary angioplasty with stent placement. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-01-01 2023-07-29T13:15:29Z 2023-07-29T13:15:29Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.3389/fdmed.2021.673626 Frontiers in Dental Medicine, v. 2. 2673-4915 http://hdl.handle.net/11449/247414 10.3389/fdmed.2021.673626 2-s2.0-85159903318 |
url |
http://dx.doi.org/10.3389/fdmed.2021.673626 http://hdl.handle.net/11449/247414 |
identifier_str_mv |
Frontiers in Dental Medicine, v. 2. 2673-4915 10.3389/fdmed.2021.673626 2-s2.0-85159903318 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Frontiers in Dental Medicine |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1799964819313393664 |