TP, APTT and fibrinogen reference values in healthy beagle breed dogs

Detalhes bibliográficos
Autor(a) principal: da Rocha Neves Cruz, Nathan [UNESP]
Data de Publicação: 2020
Outros Autores: Martinelli, Amanda Esteves [UNESP], Delgado Brito, Helena Cristina [UNESP], Santana, Aureo Evangelista [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.21708/avb.2020.14.1.8631
http://hdl.handle.net/11449/232984
Resumo: Background: Hemostasis is a process of blood coagulation with the function of preventing hemorrhagic processes in the organism. The Coagulation Time (CT), Prothrombin Time (PT), Activated Partial Thromboplastin Time (APTT), Fibrinogen, Thrombin Time (TT), Increased Fibrin Degradation Products (IFDP) and D-Dimers are laboratory tests that can be used to evaluate the coagulation cascade. Objectives: The present study aimed to determine the reference values of PT, APTT and Fibrinogen by semi-automatic methodology with laboratorial kits. Methods: Blood samples were collected from 22 healthy beagle dogs and immediately centrifuged and citrated plasma stored at -20ºC for posterior analysis. PT, APTT and fibrinogen were measured using commercial kits in a semi-automatic coagulometer by the viscosity detection system. Results: Mean values obtained were 6.0 ± 7.3 seconds for PT, 8.4 ± 16.9 seconds for APTT, and 10.2 ± 26.4 seconds for Fibrinogen. Conclusion: It is concluded that the values obtained in this work can be used as reference for healthy Beagles.
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spelling TP, APTT and fibrinogen reference values in healthy beagle breed dogsValores de referência de tempo de protrombina (TP), tempo de tromboplastina parcial ativada (TTPA) e fibrinogênio em cães hígidos da raça beagleBloodCanineClotting timeHemostasiaBackground: Hemostasis is a process of blood coagulation with the function of preventing hemorrhagic processes in the organism. The Coagulation Time (CT), Prothrombin Time (PT), Activated Partial Thromboplastin Time (APTT), Fibrinogen, Thrombin Time (TT), Increased Fibrin Degradation Products (IFDP) and D-Dimers are laboratory tests that can be used to evaluate the coagulation cascade. Objectives: The present study aimed to determine the reference values of PT, APTT and Fibrinogen by semi-automatic methodology with laboratorial kits. Methods: Blood samples were collected from 22 healthy beagle dogs and immediately centrifuged and citrated plasma stored at -20ºC for posterior analysis. PT, APTT and fibrinogen were measured using commercial kits in a semi-automatic coagulometer by the viscosity detection system. Results: Mean values obtained were 6.0 ± 7.3 seconds for PT, 8.4 ± 16.9 seconds for APTT, and 10.2 ± 26.4 seconds for Fibrinogen. Conclusion: It is concluded that the values obtained in this work can be used as reference for healthy Beagles.São Paulo State UniversitySão Paulo State UniversityUniversidade Estadual Paulista (UNESP)da Rocha Neves Cruz, Nathan [UNESP]Martinelli, Amanda Esteves [UNESP]Delgado Brito, Helena Cristina [UNESP]Santana, Aureo Evangelista [UNESP]2022-04-30T22:56:33Z2022-04-30T22:56:33Z2020-03-14info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10-15http://dx.doi.org/10.21708/avb.2020.14.1.8631Acta Veterinaria Brasilica, v. 14, n. 1, p. 10-15, 2020.1981-5484http://hdl.handle.net/11449/23298410.21708/avb.2020.14.1.86312-s2.0-85083492762Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengActa Veterinaria Brasilicainfo:eu-repo/semantics/openAccess2024-06-06T14:09:53Zoai:repositorio.unesp.br:11449/232984Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T17:10:29.469549Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv TP, APTT and fibrinogen reference values in healthy beagle breed dogs
Valores de referência de tempo de protrombina (TP), tempo de tromboplastina parcial ativada (TTPA) e fibrinogênio em cães hígidos da raça beagle
title TP, APTT and fibrinogen reference values in healthy beagle breed dogs
spellingShingle TP, APTT and fibrinogen reference values in healthy beagle breed dogs
da Rocha Neves Cruz, Nathan [UNESP]
Blood
Canine
Clotting time
Hemostasia
title_short TP, APTT and fibrinogen reference values in healthy beagle breed dogs
title_full TP, APTT and fibrinogen reference values in healthy beagle breed dogs
title_fullStr TP, APTT and fibrinogen reference values in healthy beagle breed dogs
title_full_unstemmed TP, APTT and fibrinogen reference values in healthy beagle breed dogs
title_sort TP, APTT and fibrinogen reference values in healthy beagle breed dogs
author da Rocha Neves Cruz, Nathan [UNESP]
author_facet da Rocha Neves Cruz, Nathan [UNESP]
Martinelli, Amanda Esteves [UNESP]
Delgado Brito, Helena Cristina [UNESP]
Santana, Aureo Evangelista [UNESP]
author_role author
author2 Martinelli, Amanda Esteves [UNESP]
Delgado Brito, Helena Cristina [UNESP]
Santana, Aureo Evangelista [UNESP]
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (UNESP)
dc.contributor.author.fl_str_mv da Rocha Neves Cruz, Nathan [UNESP]
Martinelli, Amanda Esteves [UNESP]
Delgado Brito, Helena Cristina [UNESP]
Santana, Aureo Evangelista [UNESP]
dc.subject.por.fl_str_mv Blood
Canine
Clotting time
Hemostasia
topic Blood
Canine
Clotting time
Hemostasia
description Background: Hemostasis is a process of blood coagulation with the function of preventing hemorrhagic processes in the organism. The Coagulation Time (CT), Prothrombin Time (PT), Activated Partial Thromboplastin Time (APTT), Fibrinogen, Thrombin Time (TT), Increased Fibrin Degradation Products (IFDP) and D-Dimers are laboratory tests that can be used to evaluate the coagulation cascade. Objectives: The present study aimed to determine the reference values of PT, APTT and Fibrinogen by semi-automatic methodology with laboratorial kits. Methods: Blood samples were collected from 22 healthy beagle dogs and immediately centrifuged and citrated plasma stored at -20ºC for posterior analysis. PT, APTT and fibrinogen were measured using commercial kits in a semi-automatic coagulometer by the viscosity detection system. Results: Mean values obtained were 6.0 ± 7.3 seconds for PT, 8.4 ± 16.9 seconds for APTT, and 10.2 ± 26.4 seconds for Fibrinogen. Conclusion: It is concluded that the values obtained in this work can be used as reference for healthy Beagles.
publishDate 2020
dc.date.none.fl_str_mv 2020-03-14
2022-04-30T22:56:33Z
2022-04-30T22:56:33Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.21708/avb.2020.14.1.8631
Acta Veterinaria Brasilica, v. 14, n. 1, p. 10-15, 2020.
1981-5484
http://hdl.handle.net/11449/232984
10.21708/avb.2020.14.1.8631
2-s2.0-85083492762
url http://dx.doi.org/10.21708/avb.2020.14.1.8631
http://hdl.handle.net/11449/232984
identifier_str_mv Acta Veterinaria Brasilica, v. 14, n. 1, p. 10-15, 2020.
1981-5484
10.21708/avb.2020.14.1.8631
2-s2.0-85083492762
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Acta Veterinaria Brasilica
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 10-15
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808128766890737664

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