Chronic consumption of fructose rich soft drinks alters tissue lipids of rats
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1186/1758-5996-2-43 http://hdl.handle.net/11449/42411 |
Resumo: | Background: Fructose-based diets are apparently related to the occurrence of several metabolic dysfunctions, but the effects of the consumption of high amounts of fructose on body tissues have not been well described. The aim of this study was to analyze the general characteristics and the lipid content of different tissues of rats after chronic ingestion of a fructose rich soft drink.Methods: Forty-five Wistar rats were used. The rats were divided into three groups (n = 15) and allowed to consume water (C), light Coca Cola (R) (L) or regular Coca Cola (R) (R) as the sole source of liquids for eight weeks.Results: The R group presented significantly higher daily liquid intake and significantly lower food intake than the C and L groups. Moreover, relative to the C and L groups, the R group showed higher triglyceride concentrations in the serum and liver. However, the L group animals presented lower values of serum triglycerides and cholesterol than controls.Conclusions: Based on the results, it can be concluded that daily ingestion of a large amount of fructose-rich soft drink resulted in unfavorable alterations to the lipid profile of the rats. |
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Repositório Institucional da UNESP |
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spelling |
Chronic consumption of fructose rich soft drinks alters tissue lipids of ratsBackground: Fructose-based diets are apparently related to the occurrence of several metabolic dysfunctions, but the effects of the consumption of high amounts of fructose on body tissues have not been well described. The aim of this study was to analyze the general characteristics and the lipid content of different tissues of rats after chronic ingestion of a fructose rich soft drink.Methods: Forty-five Wistar rats were used. The rats were divided into three groups (n = 15) and allowed to consume water (C), light Coca Cola (R) (L) or regular Coca Cola (R) (R) as the sole source of liquids for eight weeks.Results: The R group presented significantly higher daily liquid intake and significantly lower food intake than the C and L groups. Moreover, relative to the C and L groups, the R group showed higher triglyceride concentrations in the serum and liver. However, the L group animals presented lower values of serum triglycerides and cholesterol than controls.Conclusions: Based on the results, it can be concluded that daily ingestion of a large amount of fructose-rich soft drink resulted in unfavorable alterations to the lipid profile of the rats.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)São Paulo State Univ UNESP, Dept Phys Educ, BR-13506900 São Paulo, BrazilSão Paulo State Univ UNESP, Dept Phys Educ, BR-13506900 São Paulo, BrazilBiomed Central Ltd.Universidade Estadual Paulista (Unesp)Botezelli, Jose D. [UNESP]Dalia, Rodrigo A. [UNESP]Reis, Ivan M. [UNESP]Barbieri, Ricardo A. [UNESP]Rezende, Tiago M. [UNESP]Pelarigo, Jailton G. [UNESP]Codogno, Jamile [UNESP]Goncalves, Raquel [UNESP]Mello, Maria A. [UNESP]2014-05-20T15:34:05Z2014-05-20T15:34:05Z2010-06-23info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article8application/pdfhttp://dx.doi.org/10.1186/1758-5996-2-43Diabetology & Metabolic Syndrome. London: Biomed Central Ltd., v. 2, p. 8, 2010.1758-5996http://hdl.handle.net/11449/4241110.1186/1758-5996-2-43WOS:000290261000002WOS000290261000002.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengDiabetology & Metabolic Syndrome2.4130,943info:eu-repo/semantics/openAccess2024-01-16T06:25:23Zoai:repositorio.unesp.br:11449/42411Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T23:06:25.212844Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Chronic consumption of fructose rich soft drinks alters tissue lipids of rats |
title |
Chronic consumption of fructose rich soft drinks alters tissue lipids of rats |
spellingShingle |
Chronic consumption of fructose rich soft drinks alters tissue lipids of rats Botezelli, Jose D. [UNESP] |
title_short |
Chronic consumption of fructose rich soft drinks alters tissue lipids of rats |
title_full |
Chronic consumption of fructose rich soft drinks alters tissue lipids of rats |
title_fullStr |
Chronic consumption of fructose rich soft drinks alters tissue lipids of rats |
title_full_unstemmed |
Chronic consumption of fructose rich soft drinks alters tissue lipids of rats |
title_sort |
Chronic consumption of fructose rich soft drinks alters tissue lipids of rats |
author |
Botezelli, Jose D. [UNESP] |
author_facet |
Botezelli, Jose D. [UNESP] Dalia, Rodrigo A. [UNESP] Reis, Ivan M. [UNESP] Barbieri, Ricardo A. [UNESP] Rezende, Tiago M. [UNESP] Pelarigo, Jailton G. [UNESP] Codogno, Jamile [UNESP] Goncalves, Raquel [UNESP] Mello, Maria A. [UNESP] |
author_role |
author |
author2 |
Dalia, Rodrigo A. [UNESP] Reis, Ivan M. [UNESP] Barbieri, Ricardo A. [UNESP] Rezende, Tiago M. [UNESP] Pelarigo, Jailton G. [UNESP] Codogno, Jamile [UNESP] Goncalves, Raquel [UNESP] Mello, Maria A. [UNESP] |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Botezelli, Jose D. [UNESP] Dalia, Rodrigo A. [UNESP] Reis, Ivan M. [UNESP] Barbieri, Ricardo A. [UNESP] Rezende, Tiago M. [UNESP] Pelarigo, Jailton G. [UNESP] Codogno, Jamile [UNESP] Goncalves, Raquel [UNESP] Mello, Maria A. [UNESP] |
description |
Background: Fructose-based diets are apparently related to the occurrence of several metabolic dysfunctions, but the effects of the consumption of high amounts of fructose on body tissues have not been well described. The aim of this study was to analyze the general characteristics and the lipid content of different tissues of rats after chronic ingestion of a fructose rich soft drink.Methods: Forty-five Wistar rats were used. The rats were divided into three groups (n = 15) and allowed to consume water (C), light Coca Cola (R) (L) or regular Coca Cola (R) (R) as the sole source of liquids for eight weeks.Results: The R group presented significantly higher daily liquid intake and significantly lower food intake than the C and L groups. Moreover, relative to the C and L groups, the R group showed higher triglyceride concentrations in the serum and liver. However, the L group animals presented lower values of serum triglycerides and cholesterol than controls.Conclusions: Based on the results, it can be concluded that daily ingestion of a large amount of fructose-rich soft drink resulted in unfavorable alterations to the lipid profile of the rats. |
publishDate |
2010 |
dc.date.none.fl_str_mv |
2010-06-23 2014-05-20T15:34:05Z 2014-05-20T15:34:05Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1186/1758-5996-2-43 Diabetology & Metabolic Syndrome. London: Biomed Central Ltd., v. 2, p. 8, 2010. 1758-5996 http://hdl.handle.net/11449/42411 10.1186/1758-5996-2-43 WOS:000290261000002 WOS000290261000002.pdf |
url |
http://dx.doi.org/10.1186/1758-5996-2-43 http://hdl.handle.net/11449/42411 |
identifier_str_mv |
Diabetology & Metabolic Syndrome. London: Biomed Central Ltd., v. 2, p. 8, 2010. 1758-5996 10.1186/1758-5996-2-43 WOS:000290261000002 WOS000290261000002.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Diabetology & Metabolic Syndrome 2.413 0,943 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
8 application/pdf |
dc.publisher.none.fl_str_mv |
Biomed Central Ltd. |
publisher.none.fl_str_mv |
Biomed Central Ltd. |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129490918834176 |