Low frequency of Y anomaly detected in Australian Brahman cow-herds
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.mgene.2015.01.001 http://hdl.handle.net/11449/131339 |
Resumo: | Indicine cattle have lower reproductive performance in comparison to taurine. A chromosomal anomaly characterized by the presence Y markers in females was reported and associated with infertility in cattle. The aim of this study was to investigate the occurrence of the anomaly in Brahman cows. Brahman cows (n = 929) were genotyped for a Y chromosome specific region using real time-PCR. Only six out of 929 cows had the anomaly (0.6%). The anomaly frequency was much lower in Brahman cows than in the crossbred population, in which it was first detected. It also seems that the anomaly doesn't affect pregnancy in the population. Due to the low frequency, association analyses couldn't be executed. Further, SNP signal of the pseudoautosomal boundary region of the Y chromosome was investigated using HD SNP chip. Pooled DNA of non-pregnant and pregnant cows were compared and no difference in SNP allele frequency was observed. Results suggest that the anomaly had a very low frequency in this Australian Brahman population and had no effect on reproduction. Further studies comparing pregnant cows and cows that failed to conceive should be executed after better assembly and annotation of the Y chromosome in cattle. |
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Low frequency of Y anomaly detected in Australian Brahman cow-herdsBos indicusFertilityReproductionSex chromosomesY translocationIndicine cattle have lower reproductive performance in comparison to taurine. A chromosomal anomaly characterized by the presence Y markers in females was reported and associated with infertility in cattle. The aim of this study was to investigate the occurrence of the anomaly in Brahman cows. Brahman cows (n = 929) were genotyped for a Y chromosome specific region using real time-PCR. Only six out of 929 cows had the anomaly (0.6%). The anomaly frequency was much lower in Brahman cows than in the crossbred population, in which it was first detected. It also seems that the anomaly doesn't affect pregnancy in the population. Due to the low frequency, association analyses couldn't be executed. Further, SNP signal of the pseudoautosomal boundary region of the Y chromosome was investigated using HD SNP chip. Pooled DNA of non-pregnant and pregnant cows were compared and no difference in SNP allele frequency was observed. Results suggest that the anomaly had a very low frequency in this Australian Brahman population and had no effect on reproduction. Further studies comparing pregnant cows and cows that failed to conceive should be executed after better assembly and annotation of the Y chromosome in cattle.CSIRO Agriculture, Queensland Bioscience Precinct, Brisbane, QLD 4067, AustraliaSchool of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD 4067, AustraliaQueensland Alliance for Agriculture and Food Innovation, Centre for Animal Science, The University of Queensland, Brisbane, QLD 4067, Australia.Universidade Estadual Paulista (Unesp), Departamento de Zootecnia, Jaboticabal, SP 14884-900, BrazilElsevier B. V.Universidade Estadual Paulista (Unesp)Commonwealth Scientific and Industrial Research Organisation (CSIRO)University of QueenslandCamargo, Gregório M. F. de [UNESP]Porto-Neto, Laercio R.Fortes, Marina R. S.Bunch, Rowan J.Tonhati, Humberto [UNESP]Reverter, AntonioMoore, Stephen S.Lehnert, Sigrid A.2015-12-07T15:34:04Z2015-12-07T15:34:04Z2015info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article59-61application/pdfhttp://dx.doi.org/10.1016/j.mgene.2015.01.001Meta Gene, v. 3, p. 59-61, 2015.2214-5400http://hdl.handle.net/11449/13133910.1016/j.mgene.2015.01.001PMC4349192.pdf744525496085815925750859PMC4349192PubMedreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengMeta Gene0,598info:eu-repo/semantics/openAccess2024-06-07T18:41:05Zoai:repositorio.unesp.br:11449/131339Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T17:03:20.402452Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Low frequency of Y anomaly detected in Australian Brahman cow-herds |
title |
Low frequency of Y anomaly detected in Australian Brahman cow-herds |
spellingShingle |
Low frequency of Y anomaly detected in Australian Brahman cow-herds Camargo, Gregório M. F. de [UNESP] Bos indicus Fertility Reproduction Sex chromosomes Y translocation |
title_short |
Low frequency of Y anomaly detected in Australian Brahman cow-herds |
title_full |
Low frequency of Y anomaly detected in Australian Brahman cow-herds |
title_fullStr |
Low frequency of Y anomaly detected in Australian Brahman cow-herds |
title_full_unstemmed |
Low frequency of Y anomaly detected in Australian Brahman cow-herds |
title_sort |
Low frequency of Y anomaly detected in Australian Brahman cow-herds |
author |
Camargo, Gregório M. F. de [UNESP] |
author_facet |
Camargo, Gregório M. F. de [UNESP] Porto-Neto, Laercio R. Fortes, Marina R. S. Bunch, Rowan J. Tonhati, Humberto [UNESP] Reverter, Antonio Moore, Stephen S. Lehnert, Sigrid A. |
author_role |
author |
author2 |
Porto-Neto, Laercio R. Fortes, Marina R. S. Bunch, Rowan J. Tonhati, Humberto [UNESP] Reverter, Antonio Moore, Stephen S. Lehnert, Sigrid A. |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Commonwealth Scientific and Industrial Research Organisation (CSIRO) University of Queensland |
dc.contributor.author.fl_str_mv |
Camargo, Gregório M. F. de [UNESP] Porto-Neto, Laercio R. Fortes, Marina R. S. Bunch, Rowan J. Tonhati, Humberto [UNESP] Reverter, Antonio Moore, Stephen S. Lehnert, Sigrid A. |
dc.subject.por.fl_str_mv |
Bos indicus Fertility Reproduction Sex chromosomes Y translocation |
topic |
Bos indicus Fertility Reproduction Sex chromosomes Y translocation |
description |
Indicine cattle have lower reproductive performance in comparison to taurine. A chromosomal anomaly characterized by the presence Y markers in females was reported and associated with infertility in cattle. The aim of this study was to investigate the occurrence of the anomaly in Brahman cows. Brahman cows (n = 929) were genotyped for a Y chromosome specific region using real time-PCR. Only six out of 929 cows had the anomaly (0.6%). The anomaly frequency was much lower in Brahman cows than in the crossbred population, in which it was first detected. It also seems that the anomaly doesn't affect pregnancy in the population. Due to the low frequency, association analyses couldn't be executed. Further, SNP signal of the pseudoautosomal boundary region of the Y chromosome was investigated using HD SNP chip. Pooled DNA of non-pregnant and pregnant cows were compared and no difference in SNP allele frequency was observed. Results suggest that the anomaly had a very low frequency in this Australian Brahman population and had no effect on reproduction. Further studies comparing pregnant cows and cows that failed to conceive should be executed after better assembly and annotation of the Y chromosome in cattle. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-12-07T15:34:04Z 2015-12-07T15:34:04Z 2015 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.mgene.2015.01.001 Meta Gene, v. 3, p. 59-61, 2015. 2214-5400 http://hdl.handle.net/11449/131339 10.1016/j.mgene.2015.01.001 PMC4349192.pdf 7445254960858159 25750859 PMC4349192 |
url |
http://dx.doi.org/10.1016/j.mgene.2015.01.001 http://hdl.handle.net/11449/131339 |
identifier_str_mv |
Meta Gene, v. 3, p. 59-61, 2015. 2214-5400 10.1016/j.mgene.2015.01.001 PMC4349192.pdf 7445254960858159 25750859 PMC4349192 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Meta Gene 0,598 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
59-61 application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier B. V. |
publisher.none.fl_str_mv |
Elsevier B. V. |
dc.source.none.fl_str_mv |
PubMed reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128746722426880 |