Galleria mellonella as a model host for human pathogens: Recent studies and new perspectives
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.4161/viru.22493 http://hdl.handle.net/11449/227051 |
Resumo: | The number of studies using G. mellonella as a model host for human pathogens has increased significantly in the last few years. Important studies were published from different countries for evaluating the pathogenesis of bacterial and fungal infections and for exploring the host defenses against pathogens. Therefore, standardized conditions for the use of G. melonella larvae need to be established. Recent research showed that the deprivation of G. mellonella larvae of food during the experiment caused a reduction in immune responses and an increased susceptibility to infection, suggesting that incubating of larvae in the presence or absence of nutrition may affect the results and comparisons among different laboratories. © 2012 Landes Bioscience. |
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Galleria mellonella as a model host for human pathogens: Recent studies and new perspectivesBacterial pathogenesisFungal pathogenesisGalleria mellonellaInfectionInvertebrate modelsThe number of studies using G. mellonella as a model host for human pathogens has increased significantly in the last few years. Important studies were published from different countries for evaluating the pathogenesis of bacterial and fungal infections and for exploring the host defenses against pathogens. Therefore, standardized conditions for the use of G. melonella larvae need to be established. Recent research showed that the deprivation of G. mellonella larvae of food during the experiment caused a reduction in immune responses and an increased susceptibility to infection, suggesting that incubating of larvae in the presence or absence of nutrition may affect the results and comparisons among different laboratories. © 2012 Landes Bioscience.Department of Biosciences and Oral Diagnosis São José dos Campos Dental School Universidade Estadual Paulista/UNESP, São PauloDepartment of Biosciences and Oral Diagnosis São José dos Campos Dental School Universidade Estadual Paulista/UNESP, São PauloUniversidade Estadual Paulista (UNESP)Junqueira, Juliana Campos [UNESP]2022-04-29T06:01:27Z2022-04-29T06:01:27Z2012-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.4161/viru.22493Virulence, v. 3, n. 6, 2012.2150-56082150-5594http://hdl.handle.net/11449/22705110.4161/viru.224932-s2.0-84870523148Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengVirulenceinfo:eu-repo/semantics/openAccess2022-04-29T06:01:27Zoai:repositorio.unesp.br:11449/227051Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T23:49:05.160075Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Galleria mellonella as a model host for human pathogens: Recent studies and new perspectives |
title |
Galleria mellonella as a model host for human pathogens: Recent studies and new perspectives |
spellingShingle |
Galleria mellonella as a model host for human pathogens: Recent studies and new perspectives Junqueira, Juliana Campos [UNESP] Bacterial pathogenesis Fungal pathogenesis Galleria mellonella Infection Invertebrate models |
title_short |
Galleria mellonella as a model host for human pathogens: Recent studies and new perspectives |
title_full |
Galleria mellonella as a model host for human pathogens: Recent studies and new perspectives |
title_fullStr |
Galleria mellonella as a model host for human pathogens: Recent studies and new perspectives |
title_full_unstemmed |
Galleria mellonella as a model host for human pathogens: Recent studies and new perspectives |
title_sort |
Galleria mellonella as a model host for human pathogens: Recent studies and new perspectives |
author |
Junqueira, Juliana Campos [UNESP] |
author_facet |
Junqueira, Juliana Campos [UNESP] |
author_role |
author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Junqueira, Juliana Campos [UNESP] |
dc.subject.por.fl_str_mv |
Bacterial pathogenesis Fungal pathogenesis Galleria mellonella Infection Invertebrate models |
topic |
Bacterial pathogenesis Fungal pathogenesis Galleria mellonella Infection Invertebrate models |
description |
The number of studies using G. mellonella as a model host for human pathogens has increased significantly in the last few years. Important studies were published from different countries for evaluating the pathogenesis of bacterial and fungal infections and for exploring the host defenses against pathogens. Therefore, standardized conditions for the use of G. melonella larvae need to be established. Recent research showed that the deprivation of G. mellonella larvae of food during the experiment caused a reduction in immune responses and an increased susceptibility to infection, suggesting that incubating of larvae in the presence or absence of nutrition may affect the results and comparisons among different laboratories. © 2012 Landes Bioscience. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-01-01 2022-04-29T06:01:27Z 2022-04-29T06:01:27Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.4161/viru.22493 Virulence, v. 3, n. 6, 2012. 2150-5608 2150-5594 http://hdl.handle.net/11449/227051 10.4161/viru.22493 2-s2.0-84870523148 |
url |
http://dx.doi.org/10.4161/viru.22493 http://hdl.handle.net/11449/227051 |
identifier_str_mv |
Virulence, v. 3, n. 6, 2012. 2150-5608 2150-5594 10.4161/viru.22493 2-s2.0-84870523148 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Virulence |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129555066519552 |