Female Adults with Patellofemoral Pain Are Characterized by Widespread Hyperalgesia, Which Is Not Affected Immediately by Patellofemoral Joint Loading

Detalhes bibliográficos
Autor(a) principal: Pazzinatto, Marcella Ferraz
Data de Publicação: 2016
Outros Autores: Silva, Danilo de Oliveira, Barton, Christian, Rathleff, Michael Skovdal, Briani, Ronaldo Valdir, Azevedo, Fabio Micolis de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1093/pm/pnw068
http://hdl.handle.net/11449/164758
Resumo: Objective. Compare pressure pain thresholds (PPTs) at the knee and a site remote to the knee in female adults with patellofemoral pain (PFP) to pain-free controls before and after a patellofemoral joint (PFJ) loading protocol designed to aggravate symptoms. Design. Cross-sectional study Setting. Participants were recruited via advertisements in fitness centers, public places for physical activity and universities. Subjects. Thirty-eight females with patellofemoral pain, and 33 female pain-free controls. Methods. All participant performed a novel PFJ loading protocol involving stair negotiation with an extra load equivalent 35% of body mass. PPTs and current knee pain (measured on a visual analogue scale) was assessed before and after the loading protocol. PPTs were measured at four sites around the knee and one remote site on the upper contralateral limb. Results. Females with PFP demonstrated significantly lower PPTs locally and remote to the knee, both before and after the PFJ loading protocol when compared to control group. Following the loading protocol, PPTs at knee were significantly reduced by 0.54 kgf (95% CI = 0.33; 0.74) for quadriceps tendon, 0.38 kgf (95% CI = 0.14; 0.63) for medial patella, and 0.44 kgf (95% CI = 0.18; 0.69) for lateral patella. No significant change in PPT remote to the knee was observed -0.10 kgf (95% CI = -0.04; 0.24). Conclusions. Female adults with PFP have local and widespread hyperalgesia compared to pain free controls. A novel loading protocol designed to aggravate symptoms, lowers the PPTs locally at the knee but has no effect on PPT on the upper contralateral limb. This suggests widespread hyperalgesia is not affected by acute symptom aggravation.
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spelling Female Adults with Patellofemoral Pain Are Characterized by Widespread Hyperalgesia, Which Is Not Affected Immediately by Patellofemoral Joint LoadingPatellofemoral Pain SyndromeCentral Nervous System SensitizationHypersensitivity ImmediatePain ThresholdVisual Analogue Pain ScaleObjective. Compare pressure pain thresholds (PPTs) at the knee and a site remote to the knee in female adults with patellofemoral pain (PFP) to pain-free controls before and after a patellofemoral joint (PFJ) loading protocol designed to aggravate symptoms. Design. Cross-sectional study Setting. Participants were recruited via advertisements in fitness centers, public places for physical activity and universities. Subjects. Thirty-eight females with patellofemoral pain, and 33 female pain-free controls. Methods. All participant performed a novel PFJ loading protocol involving stair negotiation with an extra load equivalent 35% of body mass. PPTs and current knee pain (measured on a visual analogue scale) was assessed before and after the loading protocol. PPTs were measured at four sites around the knee and one remote site on the upper contralateral limb. Results. Females with PFP demonstrated significantly lower PPTs locally and remote to the knee, both before and after the PFJ loading protocol when compared to control group. Following the loading protocol, PPTs at knee were significantly reduced by 0.54 kgf (95% CI = 0.33; 0.74) for quadriceps tendon, 0.38 kgf (95% CI = 0.14; 0.63) for medial patella, and 0.44 kgf (95% CI = 0.18; 0.69) for lateral patella. No significant change in PPT remote to the knee was observed -0.10 kgf (95% CI = -0.04; 0.24). Conclusions. Female adults with PFP have local and widespread hyperalgesia compared to pain free controls. A novel loading protocol designed to aggravate symptoms, lowers the PPTs locally at the knee but has no effect on PPT on the upper contralateral limb. This suggests widespread hyperalgesia is not affected by acute symptom aggravation.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Univ Sao Paulo State, Phys Therapy Dept, Sch Sci & Technol Presidente Prudente, Presidente Prudente, BrazilLa Trobe Univ, Dept Phys Therapy, Sch Allied Hlth, Coll Sci Hlth & Engn, Bundoora, Vic, AustraliaQueen Mary Univ London, Ctr Sports & Exercise Med, London, EnglandAalborg Univ, Res Unit Gen Practice, Aalborg, DenmarkAalborg Univ, Dept Clin Med, Aalborg, DenmarkFAPESP: 2014/24939-7: 2014/10839-0: 2015/11534-1Oxford Univ PressUniversidade de São Paulo (USP)La Trobe UnivQueen Mary Univ LondonAalborg UnivUniversidade Estadual Paulista (Unesp)Pazzinatto, Marcella FerrazSilva, Danilo de OliveiraBarton, ChristianRathleff, Michael SkovdalBriani, Ronaldo ValdirAzevedo, Fabio Micolis de2018-11-26T17:55:59Z2018-11-26T17:55:59Z2016-10-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1953-1961application/pdfhttp://dx.doi.org/10.1093/pm/pnw068Pain Medicine. Oxford: Oxford Univ Press, v. 17, n. 10, p. 1953-1961, 2016.1526-2375http://hdl.handle.net/11449/16475810.1093/pm/pnw068WOS:000398747400021WOS000398747400021.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengPain Medicine1,087info:eu-repo/semantics/openAccess2024-06-18T18:44:28Zoai:repositorio.unesp.br:11449/164758Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T21:30:17.426730Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Female Adults with Patellofemoral Pain Are Characterized by Widespread Hyperalgesia, Which Is Not Affected Immediately by Patellofemoral Joint Loading
title Female Adults with Patellofemoral Pain Are Characterized by Widespread Hyperalgesia, Which Is Not Affected Immediately by Patellofemoral Joint Loading
spellingShingle Female Adults with Patellofemoral Pain Are Characterized by Widespread Hyperalgesia, Which Is Not Affected Immediately by Patellofemoral Joint Loading
Pazzinatto, Marcella Ferraz
Patellofemoral Pain Syndrome
Central Nervous System Sensitization
Hypersensitivity Immediate
Pain Threshold
Visual Analogue Pain Scale
title_short Female Adults with Patellofemoral Pain Are Characterized by Widespread Hyperalgesia, Which Is Not Affected Immediately by Patellofemoral Joint Loading
title_full Female Adults with Patellofemoral Pain Are Characterized by Widespread Hyperalgesia, Which Is Not Affected Immediately by Patellofemoral Joint Loading
title_fullStr Female Adults with Patellofemoral Pain Are Characterized by Widespread Hyperalgesia, Which Is Not Affected Immediately by Patellofemoral Joint Loading
title_full_unstemmed Female Adults with Patellofemoral Pain Are Characterized by Widespread Hyperalgesia, Which Is Not Affected Immediately by Patellofemoral Joint Loading
title_sort Female Adults with Patellofemoral Pain Are Characterized by Widespread Hyperalgesia, Which Is Not Affected Immediately by Patellofemoral Joint Loading
author Pazzinatto, Marcella Ferraz
author_facet Pazzinatto, Marcella Ferraz
Silva, Danilo de Oliveira
Barton, Christian
Rathleff, Michael Skovdal
Briani, Ronaldo Valdir
Azevedo, Fabio Micolis de
author_role author
author2 Silva, Danilo de Oliveira
Barton, Christian
Rathleff, Michael Skovdal
Briani, Ronaldo Valdir
Azevedo, Fabio Micolis de
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade de São Paulo (USP)
La Trobe Univ
Queen Mary Univ London
Aalborg Univ
Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Pazzinatto, Marcella Ferraz
Silva, Danilo de Oliveira
Barton, Christian
Rathleff, Michael Skovdal
Briani, Ronaldo Valdir
Azevedo, Fabio Micolis de
dc.subject.por.fl_str_mv Patellofemoral Pain Syndrome
Central Nervous System Sensitization
Hypersensitivity Immediate
Pain Threshold
Visual Analogue Pain Scale
topic Patellofemoral Pain Syndrome
Central Nervous System Sensitization
Hypersensitivity Immediate
Pain Threshold
Visual Analogue Pain Scale
description Objective. Compare pressure pain thresholds (PPTs) at the knee and a site remote to the knee in female adults with patellofemoral pain (PFP) to pain-free controls before and after a patellofemoral joint (PFJ) loading protocol designed to aggravate symptoms. Design. Cross-sectional study Setting. Participants were recruited via advertisements in fitness centers, public places for physical activity and universities. Subjects. Thirty-eight females with patellofemoral pain, and 33 female pain-free controls. Methods. All participant performed a novel PFJ loading protocol involving stair negotiation with an extra load equivalent 35% of body mass. PPTs and current knee pain (measured on a visual analogue scale) was assessed before and after the loading protocol. PPTs were measured at four sites around the knee and one remote site on the upper contralateral limb. Results. Females with PFP demonstrated significantly lower PPTs locally and remote to the knee, both before and after the PFJ loading protocol when compared to control group. Following the loading protocol, PPTs at knee were significantly reduced by 0.54 kgf (95% CI = 0.33; 0.74) for quadriceps tendon, 0.38 kgf (95% CI = 0.14; 0.63) for medial patella, and 0.44 kgf (95% CI = 0.18; 0.69) for lateral patella. No significant change in PPT remote to the knee was observed -0.10 kgf (95% CI = -0.04; 0.24). Conclusions. Female adults with PFP have local and widespread hyperalgesia compared to pain free controls. A novel loading protocol designed to aggravate symptoms, lowers the PPTs locally at the knee but has no effect on PPT on the upper contralateral limb. This suggests widespread hyperalgesia is not affected by acute symptom aggravation.
publishDate 2016
dc.date.none.fl_str_mv 2016-10-01
2018-11-26T17:55:59Z
2018-11-26T17:55:59Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1093/pm/pnw068
Pain Medicine. Oxford: Oxford Univ Press, v. 17, n. 10, p. 1953-1961, 2016.
1526-2375
http://hdl.handle.net/11449/164758
10.1093/pm/pnw068
WOS:000398747400021
WOS000398747400021.pdf
url http://dx.doi.org/10.1093/pm/pnw068
http://hdl.handle.net/11449/164758
identifier_str_mv Pain Medicine. Oxford: Oxford Univ Press, v. 17, n. 10, p. 1953-1961, 2016.
1526-2375
10.1093/pm/pnw068
WOS:000398747400021
WOS000398747400021.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Pain Medicine
1,087
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1953-1961
application/pdf
dc.publisher.none.fl_str_mv Oxford Univ Press
publisher.none.fl_str_mv Oxford Univ Press
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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