Left ventricular maximal systolic elastance calculated by a combination of M-mode echocardiography and standard manometry.
Autor(a) principal: | |
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Data de Publicação: | 1991 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://hdl.handle.net/11449/223927 |
Resumo: | 1. A method for obtaining the end-systolic left ventricular (LV) pressure-diameter and stress-diameter relationships in man was critically analyzed. 2. Pressure-diameter and stress-diameter relationships were determined throughout the cardiac cycle by combining standard LV manometry with M-mode echocardiography. Nine adult patients with heart disease and without heart failure were studied during intracardiac catheterization under three different conditions of arterial pressure, i.e., basal (B) condition (mean +/- SD systolic pressure, 102 +/- 10 mmHg) and two stable states of arterial hypertension (HI, 121 +/- 12 mmHg; HII, 147 +/- 17 mmHg) induced by venous infusion of phenylephrine after parasympathetic autonomic blockade with 0.04 mg/kg atropine. 3. Significant reflex heart rate variation with arterial hypertension was observed (B, 115 +/- 20 bpm; HI, 103 +/- 14 bpm; HII, 101 +/- 13 bpm) in spite of the parasympathetic blockade with atropine. The linear end-systolic pressure-diameter and stress-diameter relationships ranged from 53.0 to 160.0 mmHg/cm and from 97.0 to 195.0 g/cm3, respectively. 4. The end-systolic LV pressure-diameter and stress-diameter relationship lines presented high and variable slopes. The slopes, which are indicators of myocardial contractility, are susceptible to modifications by small deviations in the measurement of the ventricular diameter or by delay in the pressure curve recording. |
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Repositório Institucional da UNESP |
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spelling |
Left ventricular maximal systolic elastance calculated by a combination of M-mode echocardiography and standard manometry.1. A method for obtaining the end-systolic left ventricular (LV) pressure-diameter and stress-diameter relationships in man was critically analyzed. 2. Pressure-diameter and stress-diameter relationships were determined throughout the cardiac cycle by combining standard LV manometry with M-mode echocardiography. Nine adult patients with heart disease and without heart failure were studied during intracardiac catheterization under three different conditions of arterial pressure, i.e., basal (B) condition (mean +/- SD systolic pressure, 102 +/- 10 mmHg) and two stable states of arterial hypertension (HI, 121 +/- 12 mmHg; HII, 147 +/- 17 mmHg) induced by venous infusion of phenylephrine after parasympathetic autonomic blockade with 0.04 mg/kg atropine. 3. Significant reflex heart rate variation with arterial hypertension was observed (B, 115 +/- 20 bpm; HI, 103 +/- 14 bpm; HII, 101 +/- 13 bpm) in spite of the parasympathetic blockade with atropine. The linear end-systolic pressure-diameter and stress-diameter relationships ranged from 53.0 to 160.0 mmHg/cm and from 97.0 to 195.0 g/cm3, respectively. 4. The end-systolic LV pressure-diameter and stress-diameter relationship lines presented high and variable slopes. The slopes, which are indicators of myocardial contractility, are susceptible to modifications by small deviations in the measurement of the ventricular diameter or by delay in the pressure curve recording.Departamento de Clínica Médica Faculdade de Medicina de Botucatu Universidade Estadual PaulistaDepartamento de Clínica Médica Faculdade de Medicina de Botucatu Universidade Estadual PaulistaUniversidade Estadual Paulista (UNESP)Matsubara, B. B. [UNESP]Bregagnollo, E. A. [UNESP]Ribeiro, M. A. [UNESP]Tucci, P. J. [UNESP]2022-04-28T19:53:50Z2022-04-28T19:53:50Z1991-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article383-394Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.], v. 24, n. 4, p. 383-394, 1991.0100-879Xhttp://hdl.handle.net/11449/2239272-s2.0-0026284815Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBrazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.]info:eu-repo/semantics/openAccess2024-08-14T17:36:19Zoai:repositorio.unesp.br:11449/223927Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-14T17:36:19Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Left ventricular maximal systolic elastance calculated by a combination of M-mode echocardiography and standard manometry. |
title |
Left ventricular maximal systolic elastance calculated by a combination of M-mode echocardiography and standard manometry. |
spellingShingle |
Left ventricular maximal systolic elastance calculated by a combination of M-mode echocardiography and standard manometry. Matsubara, B. B. [UNESP] |
title_short |
Left ventricular maximal systolic elastance calculated by a combination of M-mode echocardiography and standard manometry. |
title_full |
Left ventricular maximal systolic elastance calculated by a combination of M-mode echocardiography and standard manometry. |
title_fullStr |
Left ventricular maximal systolic elastance calculated by a combination of M-mode echocardiography and standard manometry. |
title_full_unstemmed |
Left ventricular maximal systolic elastance calculated by a combination of M-mode echocardiography and standard manometry. |
title_sort |
Left ventricular maximal systolic elastance calculated by a combination of M-mode echocardiography and standard manometry. |
author |
Matsubara, B. B. [UNESP] |
author_facet |
Matsubara, B. B. [UNESP] Bregagnollo, E. A. [UNESP] Ribeiro, M. A. [UNESP] Tucci, P. J. [UNESP] |
author_role |
author |
author2 |
Bregagnollo, E. A. [UNESP] Ribeiro, M. A. [UNESP] Tucci, P. J. [UNESP] |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Matsubara, B. B. [UNESP] Bregagnollo, E. A. [UNESP] Ribeiro, M. A. [UNESP] Tucci, P. J. [UNESP] |
description |
1. A method for obtaining the end-systolic left ventricular (LV) pressure-diameter and stress-diameter relationships in man was critically analyzed. 2. Pressure-diameter and stress-diameter relationships were determined throughout the cardiac cycle by combining standard LV manometry with M-mode echocardiography. Nine adult patients with heart disease and without heart failure were studied during intracardiac catheterization under three different conditions of arterial pressure, i.e., basal (B) condition (mean +/- SD systolic pressure, 102 +/- 10 mmHg) and two stable states of arterial hypertension (HI, 121 +/- 12 mmHg; HII, 147 +/- 17 mmHg) induced by venous infusion of phenylephrine after parasympathetic autonomic blockade with 0.04 mg/kg atropine. 3. Significant reflex heart rate variation with arterial hypertension was observed (B, 115 +/- 20 bpm; HI, 103 +/- 14 bpm; HII, 101 +/- 13 bpm) in spite of the parasympathetic blockade with atropine. The linear end-systolic pressure-diameter and stress-diameter relationships ranged from 53.0 to 160.0 mmHg/cm and from 97.0 to 195.0 g/cm3, respectively. 4. The end-systolic LV pressure-diameter and stress-diameter relationship lines presented high and variable slopes. The slopes, which are indicators of myocardial contractility, are susceptible to modifications by small deviations in the measurement of the ventricular diameter or by delay in the pressure curve recording. |
publishDate |
1991 |
dc.date.none.fl_str_mv |
1991-01-01 2022-04-28T19:53:50Z 2022-04-28T19:53:50Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.], v. 24, n. 4, p. 383-394, 1991. 0100-879X http://hdl.handle.net/11449/223927 2-s2.0-0026284815 |
identifier_str_mv |
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.], v. 24, n. 4, p. 383-394, 1991. 0100-879X 2-s2.0-0026284815 |
url |
http://hdl.handle.net/11449/223927 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
383-394 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128186732511232 |