Antimicrobial activity of propolis and essential oils and synergism between these natural products
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992011000200006 http://hdl.handle.net/11449/18151 |
Resumo: | In the present study, Apis mellifera propolis and essential oils (EOs) obtained from aromatic plants were evaluated as alternative antimicrobials. We aimed to establish the antimicrobial activity of ethanolic extracts of propolis (EEP) from Apis mellifera and of EOs from Caryophyllus aromaticus, Zingiber officinale, Cinnamomum zeylanicum and Mentha piperita against 32 Staphylococcus aureus and Escherichia coli strains from human clinical specimens. The antimicrobials were diluted in agar and the minimal inhibitory concentrations (MIC) were found whereas MIC(90%) values were calculated. Time-kill curve assays using mixtures containing one quarter of MIC(90%) for EEP with all EOs as well cinnamon EO were performed. The cinnamon EO was found to be the most efficient, with MIC(90%) values of 1.22 and 0.96 mg x mL(-1) respectively against S. aureus and E. coli, whereas MIC(90%) of EEP were 1.86 and 20.12 mg x mL(-1) respectively against S. aureus and E. coli. The combinations of EEP with ginger and mint EOs, and cinnamon with ginger and clove EOs, showed synergistic effects. Consequently, further studies are necessary to confirm these activities in vivo and to evaluate the phytochemical characteristics of natural products. |
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Antimicrobial activity of propolis and essential oils and synergism between these natural productsApis melliferaaromatic plantsethanolic extract of propolisStaphylococcus aureusEscherichia coliIn the present study, Apis mellifera propolis and essential oils (EOs) obtained from aromatic plants were evaluated as alternative antimicrobials. We aimed to establish the antimicrobial activity of ethanolic extracts of propolis (EEP) from Apis mellifera and of EOs from Caryophyllus aromaticus, Zingiber officinale, Cinnamomum zeylanicum and Mentha piperita against 32 Staphylococcus aureus and Escherichia coli strains from human clinical specimens. The antimicrobials were diluted in agar and the minimal inhibitory concentrations (MIC) were found whereas MIC(90%) values were calculated. Time-kill curve assays using mixtures containing one quarter of MIC(90%) for EEP with all EOs as well cinnamon EO were performed. The cinnamon EO was found to be the most efficient, with MIC(90%) values of 1.22 and 0.96 mg x mL(-1) respectively against S. aureus and E. coli, whereas MIC(90%) of EEP were 1.86 and 20.12 mg x mL(-1) respectively against S. aureus and E. coli. The combinations of EEP with ginger and mint EOs, and cinnamon with ginger and clove EOs, showed synergistic effects. Consequently, further studies are necessary to confirm these activities in vivo and to evaluate the phytochemical characteristics of natural products.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Fundação para o Desenvolvimento da UNESP (FUNDUNESP)UNESP Univ Estadual Paulista, São Paulo State Univ, Botucatu Biosci Inst, Dept Microbiol & Immunol, Botucatu, SP, BrazilUNESP Univ Estadual Paulista, São Paulo State Univ, Botucatu Biosci Inst, Dept Chem & Biochem, Botucatu, SP, BrazilUNESP Univ Estadual Paulista, São Paulo State Univ, Botucatu Biosci Inst, Dept Microbiol & Immunol, Botucatu, SP, BrazilUNESP Univ Estadual Paulista, São Paulo State Univ, Botucatu Biosci Inst, Dept Chem & Biochem, Botucatu, SP, BrazilUniversidade Estadual Paulista (Unesp), Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP)Universidade Estadual Paulista (Unesp)Probst, I. S. [UNESP]Sforcin, J. M. [UNESP]Rall, V. L. M. [UNESP]Fernandes, A. A. H. [UNESP]Fernandes, A. [UNESP]2014-05-20T13:50:51Z2014-05-20T13:50:51Z2011-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article159-167application/pdfhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992011000200006Journal of Venomous Animals and Toxins Including Tropical Diseases. Botucatu: Cevap-unesp, v. 17, n. 2, p. 159-167, 2011.1678-9199http://hdl.handle.net/11449/18151S1678-91992011000200006WOS:000290866500006S1678-91992011000200006.pdf1843683720990222Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Venomous Animals and Toxins Including Tropical Diseases1.7820,573info:eu-repo/semantics/openAccess2024-01-04T06:28:02Zoai:repositorio.unesp.br:11449/18151Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-01-04T06:28:02Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Antimicrobial activity of propolis and essential oils and synergism between these natural products |
title |
Antimicrobial activity of propolis and essential oils and synergism between these natural products |
spellingShingle |
Antimicrobial activity of propolis and essential oils and synergism between these natural products Probst, I. S. [UNESP] Apis mellifera aromatic plants ethanolic extract of propolis Staphylococcus aureus Escherichia coli |
title_short |
Antimicrobial activity of propolis and essential oils and synergism between these natural products |
title_full |
Antimicrobial activity of propolis and essential oils and synergism between these natural products |
title_fullStr |
Antimicrobial activity of propolis and essential oils and synergism between these natural products |
title_full_unstemmed |
Antimicrobial activity of propolis and essential oils and synergism between these natural products |
title_sort |
Antimicrobial activity of propolis and essential oils and synergism between these natural products |
author |
Probst, I. S. [UNESP] |
author_facet |
Probst, I. S. [UNESP] Sforcin, J. M. [UNESP] Rall, V. L. M. [UNESP] Fernandes, A. A. H. [UNESP] Fernandes, A. [UNESP] |
author_role |
author |
author2 |
Sforcin, J. M. [UNESP] Rall, V. L. M. [UNESP] Fernandes, A. A. H. [UNESP] Fernandes, A. [UNESP] |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Probst, I. S. [UNESP] Sforcin, J. M. [UNESP] Rall, V. L. M. [UNESP] Fernandes, A. A. H. [UNESP] Fernandes, A. [UNESP] |
dc.subject.por.fl_str_mv |
Apis mellifera aromatic plants ethanolic extract of propolis Staphylococcus aureus Escherichia coli |
topic |
Apis mellifera aromatic plants ethanolic extract of propolis Staphylococcus aureus Escherichia coli |
description |
In the present study, Apis mellifera propolis and essential oils (EOs) obtained from aromatic plants were evaluated as alternative antimicrobials. We aimed to establish the antimicrobial activity of ethanolic extracts of propolis (EEP) from Apis mellifera and of EOs from Caryophyllus aromaticus, Zingiber officinale, Cinnamomum zeylanicum and Mentha piperita against 32 Staphylococcus aureus and Escherichia coli strains from human clinical specimens. The antimicrobials were diluted in agar and the minimal inhibitory concentrations (MIC) were found whereas MIC(90%) values were calculated. Time-kill curve assays using mixtures containing one quarter of MIC(90%) for EEP with all EOs as well cinnamon EO were performed. The cinnamon EO was found to be the most efficient, with MIC(90%) values of 1.22 and 0.96 mg x mL(-1) respectively against S. aureus and E. coli, whereas MIC(90%) of EEP were 1.86 and 20.12 mg x mL(-1) respectively against S. aureus and E. coli. The combinations of EEP with ginger and mint EOs, and cinnamon with ginger and clove EOs, showed synergistic effects. Consequently, further studies are necessary to confirm these activities in vivo and to evaluate the phytochemical characteristics of natural products. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-01-01 2014-05-20T13:50:51Z 2014-05-20T13:50:51Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992011000200006 Journal of Venomous Animals and Toxins Including Tropical Diseases. Botucatu: Cevap-unesp, v. 17, n. 2, p. 159-167, 2011. 1678-9199 http://hdl.handle.net/11449/18151 S1678-91992011000200006 WOS:000290866500006 S1678-91992011000200006.pdf 1843683720990222 |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992011000200006 http://hdl.handle.net/11449/18151 |
identifier_str_mv |
Journal of Venomous Animals and Toxins Including Tropical Diseases. Botucatu: Cevap-unesp, v. 17, n. 2, p. 159-167, 2011. 1678-9199 S1678-91992011000200006 WOS:000290866500006 S1678-91992011000200006.pdf 1843683720990222 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Venomous Animals and Toxins Including Tropical Diseases 1.782 0,573 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
159-167 application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Estadual Paulista (Unesp), Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP) |
publisher.none.fl_str_mv |
Universidade Estadual Paulista (Unesp), Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP) |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1797790202196918272 |