Estresse oxidativo sistêmico em cães com doença periodontal
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://hdl.handle.net/11449/144067 http://www.athena.biblioteca.unesp.br/exlibris/bd/cathedra/08-09-2016/000870581.pdf |
Resumo: | Periodontal disease (PD) is the most common disease of the oral cavity in dogs is inflammatory, chronic and infectious and is responsible for the production of reactive species of oxygen (ROS). Excessive ROS can lead to the situation known as oxidative stress, or imbalance of oxidants and antioxidants. Systematic review was performed on PD and oxidative stress to investigate the hypothesis that the canine PD suffers oxidative stress and this varies with the degree of the disease. To this end, we selected 22 dogs with PD, all adults, of different races and genders. The control group was made up of the same dogs, 30 days after periodontal treatment, all without any changes in physical and laboratorial examination. To evaluate oxidative stress was measured the full blood antioxidant capacity (TAC), plasma antioxidant, the total concentration of plasma oxidant (OCD), oxidative stress index, oxidative metabolism of circulating neutrophils (superoxide production by cytochemical test of reduction of nitroblue tetrazolium - NBT) and plasma lipid peroxidation (concentration of thiobarbituric reactive species - TBARS). Studies linking oxidative stress and PD are still rare in dogs, and humans with periodontitis has more oxidative stress compared to the control group. Oxidative stress in dogs PD was confirmed in peridontites (TAC decrease and increased neutrophil superoxide production), but these changes did not differ as to the degree of injury and were not significant in gingivitis. This is probably the first evidence that systemic oxidative stress occurs in canine periodontitis and that neutrophils |
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Estresse oxidativo sistêmico em cães com doença periodontalCãesOdontologia veterinariaPeriodontiteAgentes oxidantesAntioxidantesReative oxigen speciaesPeriodontal disease (PD) is the most common disease of the oral cavity in dogs is inflammatory, chronic and infectious and is responsible for the production of reactive species of oxygen (ROS). Excessive ROS can lead to the situation known as oxidative stress, or imbalance of oxidants and antioxidants. Systematic review was performed on PD and oxidative stress to investigate the hypothesis that the canine PD suffers oxidative stress and this varies with the degree of the disease. To this end, we selected 22 dogs with PD, all adults, of different races and genders. The control group was made up of the same dogs, 30 days after periodontal treatment, all without any changes in physical and laboratorial examination. To evaluate oxidative stress was measured the full blood antioxidant capacity (TAC), plasma antioxidant, the total concentration of plasma oxidant (OCD), oxidative stress index, oxidative metabolism of circulating neutrophils (superoxide production by cytochemical test of reduction of nitroblue tetrazolium - NBT) and plasma lipid peroxidation (concentration of thiobarbituric reactive species - TBARS). Studies linking oxidative stress and PD are still rare in dogs, and humans with periodontitis has more oxidative stress compared to the control group. Oxidative stress in dogs PD was confirmed in peridontites (TAC decrease and increased neutrophil superoxide production), but these changes did not differ as to the degree of injury and were not significant in gingivitis. This is probably the first evidence that systemic oxidative stress occurs in canine periodontitis and that neutrophilsCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Universidade Estadual Paulista (Unesp)Ciarlini, Paulo César [UNESP]Universidade Estadual Paulista (Unesp)Matono, Daniela [UNESP]2016-09-27T13:40:02Z2016-09-27T13:40:02Z2015-07-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis41 f.application/pdfMATONO, Daniela. Estresse oxidativo sistêmico em cães com doença periodontal. 2015. 41 f. Dissertação (mestrado) - Universidade Estadual Paulista Júlio de Mesquita Filho, Faculdade de Medicina Veterinária, 2015.http://hdl.handle.net/11449/144067000870581http://www.athena.biblioteca.unesp.br/exlibris/bd/cathedra/08-09-2016/000870581.pdf33004021075P836139400182995000000-0003-1480-5208Alephreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporinfo:eu-repo/semantics/openAccess2023-11-06T06:08:45Zoai:repositorio.unesp.br:11449/144067Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-11-06T06:08:45Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Estresse oxidativo sistêmico em cães com doença periodontal |
title |
Estresse oxidativo sistêmico em cães com doença periodontal |
spellingShingle |
Estresse oxidativo sistêmico em cães com doença periodontal Matono, Daniela [UNESP] Cães Odontologia veterinaria Periodontite Agentes oxidantes Antioxidantes Reative oxigen speciaes |
title_short |
Estresse oxidativo sistêmico em cães com doença periodontal |
title_full |
Estresse oxidativo sistêmico em cães com doença periodontal |
title_fullStr |
Estresse oxidativo sistêmico em cães com doença periodontal |
title_full_unstemmed |
Estresse oxidativo sistêmico em cães com doença periodontal |
title_sort |
Estresse oxidativo sistêmico em cães com doença periodontal |
author |
Matono, Daniela [UNESP] |
author_facet |
Matono, Daniela [UNESP] |
author_role |
author |
dc.contributor.none.fl_str_mv |
Ciarlini, Paulo César [UNESP] Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Matono, Daniela [UNESP] |
dc.subject.por.fl_str_mv |
Cães Odontologia veterinaria Periodontite Agentes oxidantes Antioxidantes Reative oxigen speciaes |
topic |
Cães Odontologia veterinaria Periodontite Agentes oxidantes Antioxidantes Reative oxigen speciaes |
description |
Periodontal disease (PD) is the most common disease of the oral cavity in dogs is inflammatory, chronic and infectious and is responsible for the production of reactive species of oxygen (ROS). Excessive ROS can lead to the situation known as oxidative stress, or imbalance of oxidants and antioxidants. Systematic review was performed on PD and oxidative stress to investigate the hypothesis that the canine PD suffers oxidative stress and this varies with the degree of the disease. To this end, we selected 22 dogs with PD, all adults, of different races and genders. The control group was made up of the same dogs, 30 days after periodontal treatment, all without any changes in physical and laboratorial examination. To evaluate oxidative stress was measured the full blood antioxidant capacity (TAC), plasma antioxidant, the total concentration of plasma oxidant (OCD), oxidative stress index, oxidative metabolism of circulating neutrophils (superoxide production by cytochemical test of reduction of nitroblue tetrazolium - NBT) and plasma lipid peroxidation (concentration of thiobarbituric reactive species - TBARS). Studies linking oxidative stress and PD are still rare in dogs, and humans with periodontitis has more oxidative stress compared to the control group. Oxidative stress in dogs PD was confirmed in peridontites (TAC decrease and increased neutrophil superoxide production), but these changes did not differ as to the degree of injury and were not significant in gingivitis. This is probably the first evidence that systemic oxidative stress occurs in canine periodontitis and that neutrophils |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-07-30 2016-09-27T13:40:02Z 2016-09-27T13:40:02Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
MATONO, Daniela. Estresse oxidativo sistêmico em cães com doença periodontal. 2015. 41 f. Dissertação (mestrado) - Universidade Estadual Paulista Júlio de Mesquita Filho, Faculdade de Medicina Veterinária, 2015. http://hdl.handle.net/11449/144067 000870581 http://www.athena.biblioteca.unesp.br/exlibris/bd/cathedra/08-09-2016/000870581.pdf 33004021075P8 3613940018299500 0000-0003-1480-5208 |
identifier_str_mv |
MATONO, Daniela. Estresse oxidativo sistêmico em cães com doença periodontal. 2015. 41 f. Dissertação (mestrado) - Universidade Estadual Paulista Júlio de Mesquita Filho, Faculdade de Medicina Veterinária, 2015. 000870581 33004021075P8 3613940018299500 0000-0003-1480-5208 |
url |
http://hdl.handle.net/11449/144067 http://www.athena.biblioteca.unesp.br/exlibris/bd/cathedra/08-09-2016/000870581.pdf |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
41 f. application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
publisher.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.source.none.fl_str_mv |
Aleph reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1803649632822099968 |