Metodologias laboratoriais para o diagnóstico de hemoglobinas variantes
Autor(a) principal: | |
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Data de Publicação: | 2006 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://hdl.handle.net/11449/224789 |
Resumo: | Among the electrophoretical methodologies for hemoglobin examinations under different experimental conditions, isoelectrofocusing and high performance liquid chromatography are the most frequently used for the detection of hemoglobin variants. Moreover, molecular techniques are also developed in many laboratories. The correct laboratorial diagnosis of hemoglobin alterations is especially important for the interactive forms principally in Brazil, because of the many associations of hemoglobin alterations and variants with co-migration. The association of classical and molecular techniques is essential for accurate identification of hemoglobin variants. |
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Metodologias laboratoriais para o diagnóstico de hemoglobinas variantesThe laboratory methodology for diagnosis of hemoglobin variantsHemoglobinopathiesHemoglobinopathy diagnosisMethodologies associationAmong the electrophoretical methodologies for hemoglobin examinations under different experimental conditions, isoelectrofocusing and high performance liquid chromatography are the most frequently used for the detection of hemoglobin variants. Moreover, molecular techniques are also developed in many laboratories. The correct laboratorial diagnosis of hemoglobin alterations is especially important for the interactive forms principally in Brazil, because of the many associations of hemoglobin alterations and variants with co-migration. The association of classical and molecular techniques is essential for accurate identification of hemoglobin variants.Programa de Pós-Graduação em Genética Instituto de Biociências, Letras e Ciências Exatas UnespLaboratorio de Hemoglobinopatias e Genetica das Doencas Hematologicas (LHGDH) Ibilce UnespLHGDH Ibilce Unesp, R. Cristovao Colombo, 2265, S. Jose do Rio Preto - SPPrograma de Pós-Graduação em Genética Instituto de Biociências, Letras e Ciências Exatas UnespLaboratorio de Hemoglobinopatias e Genetica das Doencas Hematologicas (LHGDH) Ibilce UnespLHGDH Ibilce Unesp, R. Cristovao Colombo, 2265, S. Jose do Rio Preto - SPUniversidade Estadual Paulista (UNESP)Chinelato-Fernandes, Ana R. [UNESP]Domingos, Claudia R. B. [UNESP]2022-04-28T20:08:18Z2022-04-28T20:08:18Z2006-08-23info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article65-67Revista Brasileira de Hematologia e Hemoterapia, v. 28, n. 1, p. 65-67, 2006.1516-8484http://hdl.handle.net/11449/2247892-s2.0-33747341837Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporRevista Brasileira de Hematologia e Hemoterapiainfo:eu-repo/semantics/openAccess2022-04-28T20:08:18Zoai:repositorio.unesp.br:11449/224789Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T22:07:49.498447Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Metodologias laboratoriais para o diagnóstico de hemoglobinas variantes The laboratory methodology for diagnosis of hemoglobin variants |
title |
Metodologias laboratoriais para o diagnóstico de hemoglobinas variantes |
spellingShingle |
Metodologias laboratoriais para o diagnóstico de hemoglobinas variantes Chinelato-Fernandes, Ana R. [UNESP] Hemoglobinopathies Hemoglobinopathy diagnosis Methodologies association |
title_short |
Metodologias laboratoriais para o diagnóstico de hemoglobinas variantes |
title_full |
Metodologias laboratoriais para o diagnóstico de hemoglobinas variantes |
title_fullStr |
Metodologias laboratoriais para o diagnóstico de hemoglobinas variantes |
title_full_unstemmed |
Metodologias laboratoriais para o diagnóstico de hemoglobinas variantes |
title_sort |
Metodologias laboratoriais para o diagnóstico de hemoglobinas variantes |
author |
Chinelato-Fernandes, Ana R. [UNESP] |
author_facet |
Chinelato-Fernandes, Ana R. [UNESP] Domingos, Claudia R. B. [UNESP] |
author_role |
author |
author2 |
Domingos, Claudia R. B. [UNESP] |
author2_role |
author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Chinelato-Fernandes, Ana R. [UNESP] Domingos, Claudia R. B. [UNESP] |
dc.subject.por.fl_str_mv |
Hemoglobinopathies Hemoglobinopathy diagnosis Methodologies association |
topic |
Hemoglobinopathies Hemoglobinopathy diagnosis Methodologies association |
description |
Among the electrophoretical methodologies for hemoglobin examinations under different experimental conditions, isoelectrofocusing and high performance liquid chromatography are the most frequently used for the detection of hemoglobin variants. Moreover, molecular techniques are also developed in many laboratories. The correct laboratorial diagnosis of hemoglobin alterations is especially important for the interactive forms principally in Brazil, because of the many associations of hemoglobin alterations and variants with co-migration. The association of classical and molecular techniques is essential for accurate identification of hemoglobin variants. |
publishDate |
2006 |
dc.date.none.fl_str_mv |
2006-08-23 2022-04-28T20:08:18Z 2022-04-28T20:08:18Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
Revista Brasileira de Hematologia e Hemoterapia, v. 28, n. 1, p. 65-67, 2006. 1516-8484 http://hdl.handle.net/11449/224789 2-s2.0-33747341837 |
identifier_str_mv |
Revista Brasileira de Hematologia e Hemoterapia, v. 28, n. 1, p. 65-67, 2006. 1516-8484 2-s2.0-33747341837 |
url |
http://hdl.handle.net/11449/224789 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
Revista Brasileira de Hematologia e Hemoterapia |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
65-67 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129394794823680 |