Caracterização de colágenos tipos I e III no estroma do carcinoma de células escamosas cutâneo em cães

Detalhes bibliográficos
Autor(a) principal: Bedoya, S. A.O.
Data de Publicação: 2016
Outros Autores: Conceição, L. G., Viloria, M. I.V., Loures, F. H., Valente, F. L., Amorim, R. L. [UNESP], Silva, F. F.
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/1678-4162-8484
http://hdl.handle.net/11449/168381
Resumo: Squamous cell carcinoma (SCC) is a malignant epithelial tumor that affects dogs and several other species, including humans. The SCC occurs in various anatomical sites and can develop metastasis. The aim of this study was to characterize types I and III collagen fibers in the stroma of cutaneous SCC in dogs. For this work 44 paraffin-embedded samples with previous diagnostic of SCC were used. Samples were processed and evaluated histologically with hematoxylin/eosin to confirm the diagnosis and classification of cell differentiation degree and with Picrosirius for observation of types I and III collagen. Type III collagen expression was higher in well-differentiated SCC. The role of type III collagen in cancer is not very clear and factors other than cell differentiation degree may be involved in its expression and determine its importance in tumor biology.
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spelling Caracterização de colágenos tipos I e III no estroma do carcinoma de células escamosas cutâneo em cãesCharacterization of types I and III collagen in the stroma of cutaneous squamous cell carcinoma in dogsEpithelial neoplasmHematoxylin/eosinPicrosiriusSkinSquamous cell carcinoma (SCC) is a malignant epithelial tumor that affects dogs and several other species, including humans. The SCC occurs in various anatomical sites and can develop metastasis. The aim of this study was to characterize types I and III collagen fibers in the stroma of cutaneous SCC in dogs. For this work 44 paraffin-embedded samples with previous diagnostic of SCC were used. Samples were processed and evaluated histologically with hematoxylin/eosin to confirm the diagnosis and classification of cell differentiation degree and with Picrosirius for observation of types I and III collagen. Type III collagen expression was higher in well-differentiated SCC. The role of type III collagen in cancer is not very clear and factors other than cell differentiation degree may be involved in its expression and determine its importance in tumor biology.Universidade Federal de ViçosaFaculdade de Medicina Veterinária e Zootecnia UnespFaculdade de Medicina Veterinária e Zootecnia UnespUniversidade Federal de Viçosa (UFV)Universidade Estadual Paulista (Unesp)Bedoya, S. A.O.Conceição, L. G.Viloria, M. I.V.Loures, F. H.Valente, F. L.Amorim, R. L. [UNESP]Silva, F. F.2018-12-11T16:41:02Z2018-12-11T16:41:02Z2016-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article147-154application/pdfhttp://dx.doi.org/10.1590/1678-4162-8484Arquivo Brasileiro de Medicina Veterinaria e Zootecnia, v. 68, n. 1, p. 147-154, 2016.1678-41620102-0935http://hdl.handle.net/11449/16838110.1590/1678-4162-8484S0102-093520160001001472-s2.0-84957916944S0102-09352016000100147.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporArquivo Brasileiro de Medicina Veterinaria e Zootecnia0,248info:eu-repo/semantics/openAccess2024-01-01T06:16:56Zoai:repositorio.unesp.br:11449/168381Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T21:50:02.056619Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Caracterização de colágenos tipos I e III no estroma do carcinoma de células escamosas cutâneo em cães
Characterization of types I and III collagen in the stroma of cutaneous squamous cell carcinoma in dogs
title Caracterização de colágenos tipos I e III no estroma do carcinoma de células escamosas cutâneo em cães
spellingShingle Caracterização de colágenos tipos I e III no estroma do carcinoma de células escamosas cutâneo em cães
Bedoya, S. A.O.
Epithelial neoplasm
Hematoxylin/eosin
Picrosirius
Skin
title_short Caracterização de colágenos tipos I e III no estroma do carcinoma de células escamosas cutâneo em cães
title_full Caracterização de colágenos tipos I e III no estroma do carcinoma de células escamosas cutâneo em cães
title_fullStr Caracterização de colágenos tipos I e III no estroma do carcinoma de células escamosas cutâneo em cães
title_full_unstemmed Caracterização de colágenos tipos I e III no estroma do carcinoma de células escamosas cutâneo em cães
title_sort Caracterização de colágenos tipos I e III no estroma do carcinoma de células escamosas cutâneo em cães
author Bedoya, S. A.O.
author_facet Bedoya, S. A.O.
Conceição, L. G.
Viloria, M. I.V.
Loures, F. H.
Valente, F. L.
Amorim, R. L. [UNESP]
Silva, F. F.
author_role author
author2 Conceição, L. G.
Viloria, M. I.V.
Loures, F. H.
Valente, F. L.
Amorim, R. L. [UNESP]
Silva, F. F.
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de Viçosa (UFV)
Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Bedoya, S. A.O.
Conceição, L. G.
Viloria, M. I.V.
Loures, F. H.
Valente, F. L.
Amorim, R. L. [UNESP]
Silva, F. F.
dc.subject.por.fl_str_mv Epithelial neoplasm
Hematoxylin/eosin
Picrosirius
Skin
topic Epithelial neoplasm
Hematoxylin/eosin
Picrosirius
Skin
description Squamous cell carcinoma (SCC) is a malignant epithelial tumor that affects dogs and several other species, including humans. The SCC occurs in various anatomical sites and can develop metastasis. The aim of this study was to characterize types I and III collagen fibers in the stroma of cutaneous SCC in dogs. For this work 44 paraffin-embedded samples with previous diagnostic of SCC were used. Samples were processed and evaluated histologically with hematoxylin/eosin to confirm the diagnosis and classification of cell differentiation degree and with Picrosirius for observation of types I and III collagen. Type III collagen expression was higher in well-differentiated SCC. The role of type III collagen in cancer is not very clear and factors other than cell differentiation degree may be involved in its expression and determine its importance in tumor biology.
publishDate 2016
dc.date.none.fl_str_mv 2016-01-01
2018-12-11T16:41:02Z
2018-12-11T16:41:02Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/1678-4162-8484
Arquivo Brasileiro de Medicina Veterinaria e Zootecnia, v. 68, n. 1, p. 147-154, 2016.
1678-4162
0102-0935
http://hdl.handle.net/11449/168381
10.1590/1678-4162-8484
S0102-09352016000100147
2-s2.0-84957916944
S0102-09352016000100147.pdf
url http://dx.doi.org/10.1590/1678-4162-8484
http://hdl.handle.net/11449/168381
identifier_str_mv Arquivo Brasileiro de Medicina Veterinaria e Zootecnia, v. 68, n. 1, p. 147-154, 2016.
1678-4162
0102-0935
10.1590/1678-4162-8484
S0102-09352016000100147
2-s2.0-84957916944
S0102-09352016000100147.pdf
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv Arquivo Brasileiro de Medicina Veterinaria e Zootecnia
0,248
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 147-154
application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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