Endectocide activity of a pour-on formulation containing 1.5 per cent ivermectin +0.5 per cent abamectin in cattle
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1136/vetreco-2014-000072 http://hdl.handle.net/11449/131393 |
Resumo: | The present work aimed to evaluate, through ten different studies, the therapeutic efficacy of a new pour-on formulation, containing 1.5 per cent ivermectin +0.5 per cent abamectin, against parasites of cattle. Results obtained on trials against Rhipicephalus (Boophilus) microplus showed that the pour-on combination of 1.5 per cent ivermectin +0.5 per cent abamectin obtained superior efficacy indexes against this ectoparasite, when compared with formulations containing 0.5 per cent ivermectin, 1 per cent ivermectin and the combination of 1 per cent abamectin +20 per cent levamisole. The results of efficacy of the ivermectin+abamectin and the 0.5 per cent ivermectin against Haematobia irritans were similar. Against Cochliomyia hominivorax larvae, all pour-on formulations tested (1.5 per cent ivermectin +0.5 per cent abamectin, 0.5 per cent ivermectin and 0.5 per cent abamectin), as well as 1 per cent doramectin administered subcutaneously, were considered ineffective. Cattle medicated with 1.5 per cent ivermectin +0.5 per cent abamectin, pour-on, remained free from parasitism by Dermatobia hominis larvae during 42 days (96 per cent efficacy), while values superior to 90 per cent were obtained by 0.5 per cent ivermectin (92 per cent) and 0.5 per cent abamectin (93 per cent) until the 42nd and 35th days post treatment, respectively. Against Haemonchus placei and Oesophagostomum radiatum, the pour-on of ivermectin+abamectin showed better efficacy than the 0.5 per cent ivermectin and 0.5 per cent abamectin. As to Cooperia punctata, there was no difference regarding efficacy results obtained by the avermectins combination and abamectin. The pour-on combination of 1.5 per cent ivermectin +0.5 per cent abamectin obtained high efficacy against R. (B.) microplus, D. hominis and some species of cattle gastrointestinal helminths when compared with formulations of 0.5 per cent ivermectin and 0.5 per cent abamectin administered through the same route. |
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Repositório Institucional da UNESP |
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Endectocide activity of a pour-on formulation containing 1.5 per cent ivermectin +0.5 per cent abamectin in cattleCattleDermatobia hominisAbamectinIvermectinThe present work aimed to evaluate, through ten different studies, the therapeutic efficacy of a new pour-on formulation, containing 1.5 per cent ivermectin +0.5 per cent abamectin, against parasites of cattle. Results obtained on trials against Rhipicephalus (Boophilus) microplus showed that the pour-on combination of 1.5 per cent ivermectin +0.5 per cent abamectin obtained superior efficacy indexes against this ectoparasite, when compared with formulations containing 0.5 per cent ivermectin, 1 per cent ivermectin and the combination of 1 per cent abamectin +20 per cent levamisole. The results of efficacy of the ivermectin+abamectin and the 0.5 per cent ivermectin against Haematobia irritans were similar. Against Cochliomyia hominivorax larvae, all pour-on formulations tested (1.5 per cent ivermectin +0.5 per cent abamectin, 0.5 per cent ivermectin and 0.5 per cent abamectin), as well as 1 per cent doramectin administered subcutaneously, were considered ineffective. Cattle medicated with 1.5 per cent ivermectin +0.5 per cent abamectin, pour-on, remained free from parasitism by Dermatobia hominis larvae during 42 days (96 per cent efficacy), while values superior to 90 per cent were obtained by 0.5 per cent ivermectin (92 per cent) and 0.5 per cent abamectin (93 per cent) until the 42nd and 35th days post treatment, respectively. Against Haemonchus placei and Oesophagostomum radiatum, the pour-on of ivermectin+abamectin showed better efficacy than the 0.5 per cent ivermectin and 0.5 per cent abamectin. As to Cooperia punctata, there was no difference regarding efficacy results obtained by the avermectins combination and abamectin. The pour-on combination of 1.5 per cent ivermectin +0.5 per cent abamectin obtained high efficacy against R. (B.) microplus, D. hominis and some species of cattle gastrointestinal helminths when compared with formulations of 0.5 per cent ivermectin and 0.5 per cent abamectin administered through the same route.Department of Animal Pathology, Faculdade de Ciências Agrárias e Veterinárias, UNESP/CPPAR, Via de acesso prof. Paulo Donatto Castellani , Jaboticabal, São Paulo , Brazil ; Department of Veterinary Medicine, Instituto de Ciência da Saúde da Universidade Federal da Bahia Salvador-Bahia, Brazil.Department of Animal Pathology, Faculdade de Ciências Agrárias e Veterinárias, UNESP/CPPAR, Via de acesso prof. Paulo Donatto Castellani , Jaboticabal, São Paulo , Brazil ; Departament of Veterinary Medicine, Universidade Federal da Paraíba - Campus II, Brazil.Department of Animal Pathology, Faculdade de Ciências Agrárias e Veterinárias, UNESP/CPPAR, Via de acesso prof. Paulo Donatto Castellani , Jaboticabal, São Paulo , Brazil ; Department of Veterinary Medicine, Universidade Federal de Goiás - Regional de Jataí Jataí, GO, Brazil.Department of Animal Pathology, Faculdade de Ciências Agrárias e Veterinárias, UNESP/CPPAR, Via de acesso prof. Paulo Donatto Castellani , Jaboticabal, São Paulo , Brazil.Department of Veterinary Medicine, Universidade Estadual de Maringá, Campus de Umuarama, Umuarama-Paraná, Brazil.Department of Animal Pathology, Faculdade de Ciências Agrárias e Veterinárias, UNESP/CPPAR, Via de acesso prof. Paulo Donatto Castellani , Jaboticabal, São Paulo , BrazilBMJ Publishing Group LimitedUniversidade Estadual Paulista (Unesp)Universidade Federal da Bahia (UFBA)Universidade Federal da Paraíba (UFPB)Silva, Heloisa Cristina [UNESP]Prette, Nancy [UNESP]Lopes, Welber Daniel Zanetti [UNESP]Sakamoto, Cláudio Alessandro M [UNESP]Buzzulini, Carolina [UNESP]Dos Santos, Thais Rabelo [UNESP]Cruz, Breno Cayeiro [UNESP]Teixeira, Weslen F Pires [UNESP]Felippelli, Gustavo [UNESP]Carvalho, Rafael SilveiraMaciel, Willian Giquelin [UNESP]Soares, Vando Edésio [UNESP]da Costa, Alvimar José [UNESP]2015-12-07T15:34:45Z2015-12-07T15:34:45Z2015info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1-12application/pdfhttp://dx.doi.org/10.1136/vetreco-2014-000072Veterinary Record Open, v. 2, n. 1, p. 1-12, 2015.2052-6113http://hdl.handle.net/11449/13139310.1136/vetreco-2014-000072PMC4567150.pdf26392893PMC4567150PubMedreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengVeterinary Record Openinfo:eu-repo/semantics/openAccess2024-04-12T13:07:00Zoai:repositorio.unesp.br:11449/131393Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T18:56:44.745837Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Endectocide activity of a pour-on formulation containing 1.5 per cent ivermectin +0.5 per cent abamectin in cattle |
title |
Endectocide activity of a pour-on formulation containing 1.5 per cent ivermectin +0.5 per cent abamectin in cattle |
spellingShingle |
Endectocide activity of a pour-on formulation containing 1.5 per cent ivermectin +0.5 per cent abamectin in cattle Silva, Heloisa Cristina [UNESP] Cattle Dermatobia hominis Abamectin Ivermectin |
title_short |
Endectocide activity of a pour-on formulation containing 1.5 per cent ivermectin +0.5 per cent abamectin in cattle |
title_full |
Endectocide activity of a pour-on formulation containing 1.5 per cent ivermectin +0.5 per cent abamectin in cattle |
title_fullStr |
Endectocide activity of a pour-on formulation containing 1.5 per cent ivermectin +0.5 per cent abamectin in cattle |
title_full_unstemmed |
Endectocide activity of a pour-on formulation containing 1.5 per cent ivermectin +0.5 per cent abamectin in cattle |
title_sort |
Endectocide activity of a pour-on formulation containing 1.5 per cent ivermectin +0.5 per cent abamectin in cattle |
author |
Silva, Heloisa Cristina [UNESP] |
author_facet |
Silva, Heloisa Cristina [UNESP] Prette, Nancy [UNESP] Lopes, Welber Daniel Zanetti [UNESP] Sakamoto, Cláudio Alessandro M [UNESP] Buzzulini, Carolina [UNESP] Dos Santos, Thais Rabelo [UNESP] Cruz, Breno Cayeiro [UNESP] Teixeira, Weslen F Pires [UNESP] Felippelli, Gustavo [UNESP] Carvalho, Rafael Silveira Maciel, Willian Giquelin [UNESP] Soares, Vando Edésio [UNESP] da Costa, Alvimar José [UNESP] |
author_role |
author |
author2 |
Prette, Nancy [UNESP] Lopes, Welber Daniel Zanetti [UNESP] Sakamoto, Cláudio Alessandro M [UNESP] Buzzulini, Carolina [UNESP] Dos Santos, Thais Rabelo [UNESP] Cruz, Breno Cayeiro [UNESP] Teixeira, Weslen F Pires [UNESP] Felippelli, Gustavo [UNESP] Carvalho, Rafael Silveira Maciel, Willian Giquelin [UNESP] Soares, Vando Edésio [UNESP] da Costa, Alvimar José [UNESP] |
author2_role |
author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Universidade Federal da Bahia (UFBA) Universidade Federal da Paraíba (UFPB) |
dc.contributor.author.fl_str_mv |
Silva, Heloisa Cristina [UNESP] Prette, Nancy [UNESP] Lopes, Welber Daniel Zanetti [UNESP] Sakamoto, Cláudio Alessandro M [UNESP] Buzzulini, Carolina [UNESP] Dos Santos, Thais Rabelo [UNESP] Cruz, Breno Cayeiro [UNESP] Teixeira, Weslen F Pires [UNESP] Felippelli, Gustavo [UNESP] Carvalho, Rafael Silveira Maciel, Willian Giquelin [UNESP] Soares, Vando Edésio [UNESP] da Costa, Alvimar José [UNESP] |
dc.subject.por.fl_str_mv |
Cattle Dermatobia hominis Abamectin Ivermectin |
topic |
Cattle Dermatobia hominis Abamectin Ivermectin |
description |
The present work aimed to evaluate, through ten different studies, the therapeutic efficacy of a new pour-on formulation, containing 1.5 per cent ivermectin +0.5 per cent abamectin, against parasites of cattle. Results obtained on trials against Rhipicephalus (Boophilus) microplus showed that the pour-on combination of 1.5 per cent ivermectin +0.5 per cent abamectin obtained superior efficacy indexes against this ectoparasite, when compared with formulations containing 0.5 per cent ivermectin, 1 per cent ivermectin and the combination of 1 per cent abamectin +20 per cent levamisole. The results of efficacy of the ivermectin+abamectin and the 0.5 per cent ivermectin against Haematobia irritans were similar. Against Cochliomyia hominivorax larvae, all pour-on formulations tested (1.5 per cent ivermectin +0.5 per cent abamectin, 0.5 per cent ivermectin and 0.5 per cent abamectin), as well as 1 per cent doramectin administered subcutaneously, were considered ineffective. Cattle medicated with 1.5 per cent ivermectin +0.5 per cent abamectin, pour-on, remained free from parasitism by Dermatobia hominis larvae during 42 days (96 per cent efficacy), while values superior to 90 per cent were obtained by 0.5 per cent ivermectin (92 per cent) and 0.5 per cent abamectin (93 per cent) until the 42nd and 35th days post treatment, respectively. Against Haemonchus placei and Oesophagostomum radiatum, the pour-on of ivermectin+abamectin showed better efficacy than the 0.5 per cent ivermectin and 0.5 per cent abamectin. As to Cooperia punctata, there was no difference regarding efficacy results obtained by the avermectins combination and abamectin. The pour-on combination of 1.5 per cent ivermectin +0.5 per cent abamectin obtained high efficacy against R. (B.) microplus, D. hominis and some species of cattle gastrointestinal helminths when compared with formulations of 0.5 per cent ivermectin and 0.5 per cent abamectin administered through the same route. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-12-07T15:34:45Z 2015-12-07T15:34:45Z 2015 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1136/vetreco-2014-000072 Veterinary Record Open, v. 2, n. 1, p. 1-12, 2015. 2052-6113 http://hdl.handle.net/11449/131393 10.1136/vetreco-2014-000072 PMC4567150.pdf 26392893 PMC4567150 |
url |
http://dx.doi.org/10.1136/vetreco-2014-000072 http://hdl.handle.net/11449/131393 |
identifier_str_mv |
Veterinary Record Open, v. 2, n. 1, p. 1-12, 2015. 2052-6113 10.1136/vetreco-2014-000072 PMC4567150.pdf 26392893 PMC4567150 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Veterinary Record Open |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
1-12 application/pdf |
dc.publisher.none.fl_str_mv |
BMJ Publishing Group Limited |
publisher.none.fl_str_mv |
BMJ Publishing Group Limited |
dc.source.none.fl_str_mv |
PubMed reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129001139470336 |