Endectocide activity of a pour-on formulation containing 1.5 per cent ivermectin +0.5 per cent abamectin in cattle

Detalhes bibliográficos
Autor(a) principal: Silva, Heloisa Cristina [UNESP]
Data de Publicação: 2015
Outros Autores: Prette, Nancy [UNESP], Lopes, Welber Daniel Zanetti [UNESP], Sakamoto, Cláudio Alessandro M [UNESP], Buzzulini, Carolina [UNESP], Dos Santos, Thais Rabelo [UNESP], Cruz, Breno Cayeiro [UNESP], Teixeira, Weslen F Pires [UNESP], Felippelli, Gustavo [UNESP], Carvalho, Rafael Silveira, Maciel, Willian Giquelin [UNESP], Soares, Vando Edésio [UNESP], da Costa, Alvimar José [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1136/vetreco-2014-000072
http://hdl.handle.net/11449/131393
Resumo: The present work aimed to evaluate, through ten different studies, the therapeutic efficacy of a new pour-on formulation, containing 1.5 per cent ivermectin +0.5 per cent abamectin, against parasites of cattle. Results obtained on trials against Rhipicephalus (Boophilus) microplus showed that the pour-on combination of 1.5 per cent ivermectin +0.5 per cent abamectin obtained superior efficacy indexes against this ectoparasite, when compared with formulations containing 0.5 per cent ivermectin, 1 per cent ivermectin and the combination of 1 per cent abamectin +20 per cent levamisole. The results of efficacy of the ivermectin+abamectin and the 0.5 per cent ivermectin against Haematobia irritans were similar. Against Cochliomyia hominivorax larvae, all pour-on formulations tested (1.5 per cent ivermectin +0.5 per cent abamectin, 0.5 per cent ivermectin and 0.5 per cent abamectin), as well as 1 per cent doramectin administered subcutaneously, were considered ineffective. Cattle medicated with 1.5 per cent ivermectin +0.5 per cent abamectin, pour-on, remained free from parasitism by Dermatobia hominis larvae during 42 days (96 per cent efficacy), while values superior to 90 per cent were obtained by 0.5 per cent ivermectin (92 per cent) and 0.5 per cent abamectin (93 per cent) until the 42nd and 35th days post treatment, respectively. Against Haemonchus placei and Oesophagostomum radiatum, the pour-on of ivermectin+abamectin showed better efficacy than the 0.5 per cent ivermectin and 0.5 per cent abamectin. As to Cooperia punctata, there was no difference regarding efficacy results obtained by the avermectins combination and abamectin. The pour-on combination of 1.5 per cent ivermectin +0.5 per cent abamectin obtained high efficacy against R. (B.) microplus, D. hominis and some species of cattle gastrointestinal helminths when compared with formulations of 0.5 per cent ivermectin and 0.5 per cent abamectin administered through the same route.
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spelling Endectocide activity of a pour-on formulation containing 1.5 per cent ivermectin +0.5 per cent abamectin in cattleCattleDermatobia hominisAbamectinIvermectinThe present work aimed to evaluate, through ten different studies, the therapeutic efficacy of a new pour-on formulation, containing 1.5 per cent ivermectin +0.5 per cent abamectin, against parasites of cattle. Results obtained on trials against Rhipicephalus (Boophilus) microplus showed that the pour-on combination of 1.5 per cent ivermectin +0.5 per cent abamectin obtained superior efficacy indexes against this ectoparasite, when compared with formulations containing 0.5 per cent ivermectin, 1 per cent ivermectin and the combination of 1 per cent abamectin +20 per cent levamisole. The results of efficacy of the ivermectin+abamectin and the 0.5 per cent ivermectin against Haematobia irritans were similar. Against Cochliomyia hominivorax larvae, all pour-on formulations tested (1.5 per cent ivermectin +0.5 per cent abamectin, 0.5 per cent ivermectin and 0.5 per cent abamectin), as well as 1 per cent doramectin administered subcutaneously, were considered ineffective. Cattle medicated with 1.5 per cent ivermectin +0.5 per cent abamectin, pour-on, remained free from parasitism by Dermatobia hominis larvae during 42 days (96 per cent efficacy), while values superior to 90 per cent were obtained by 0.5 per cent ivermectin (92 per cent) and 0.5 per cent abamectin (93 per cent) until the 42nd and 35th days post treatment, respectively. Against Haemonchus placei and Oesophagostomum radiatum, the pour-on of ivermectin+abamectin showed better efficacy than the 0.5 per cent ivermectin and 0.5 per cent abamectin. As to Cooperia punctata, there was no difference regarding efficacy results obtained by the avermectins combination and abamectin. The pour-on combination of 1.5 per cent ivermectin +0.5 per cent abamectin obtained high efficacy against R. (B.) microplus, D. hominis and some species of cattle gastrointestinal helminths when compared with formulations of 0.5 per cent ivermectin and 0.5 per cent abamectin administered through the same route.Department of Animal Pathology, Faculdade de Ciências Agrárias e Veterinárias, UNESP/CPPAR, Via de acesso prof. Paulo Donatto Castellani , Jaboticabal, São Paulo , Brazil ; Department of Veterinary Medicine, Instituto de Ciência da Saúde da Universidade Federal da Bahia Salvador-Bahia, Brazil.Department of Animal Pathology, Faculdade de Ciências Agrárias e Veterinárias, UNESP/CPPAR, Via de acesso prof. Paulo Donatto Castellani , Jaboticabal, São Paulo , Brazil ; Departament of Veterinary Medicine, Universidade Federal da Paraíba - Campus II, Brazil.Department of Animal Pathology, Faculdade de Ciências Agrárias e Veterinárias, UNESP/CPPAR, Via de acesso prof. Paulo Donatto Castellani , Jaboticabal, São Paulo , Brazil ; Department of Veterinary Medicine, Universidade Federal de Goiás - Regional de Jataí Jataí, GO, Brazil.Department of Animal Pathology, Faculdade de Ciências Agrárias e Veterinárias, UNESP/CPPAR, Via de acesso prof. Paulo Donatto Castellani , Jaboticabal, São Paulo , Brazil.Department of Veterinary Medicine, Universidade Estadual de Maringá, Campus de Umuarama, Umuarama-Paraná, Brazil.Department of Animal Pathology, Faculdade de Ciências Agrárias e Veterinárias, UNESP/CPPAR, Via de acesso prof. Paulo Donatto Castellani , Jaboticabal, São Paulo , BrazilBMJ Publishing Group LimitedUniversidade Estadual Paulista (Unesp)Universidade Federal da Bahia (UFBA)Universidade Federal da Paraíba (UFPB)Silva, Heloisa Cristina [UNESP]Prette, Nancy [UNESP]Lopes, Welber Daniel Zanetti [UNESP]Sakamoto, Cláudio Alessandro M [UNESP]Buzzulini, Carolina [UNESP]Dos Santos, Thais Rabelo [UNESP]Cruz, Breno Cayeiro [UNESP]Teixeira, Weslen F Pires [UNESP]Felippelli, Gustavo [UNESP]Carvalho, Rafael SilveiraMaciel, Willian Giquelin [UNESP]Soares, Vando Edésio [UNESP]da Costa, Alvimar José [UNESP]2015-12-07T15:34:45Z2015-12-07T15:34:45Z2015info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1-12application/pdfhttp://dx.doi.org/10.1136/vetreco-2014-000072Veterinary Record Open, v. 2, n. 1, p. 1-12, 2015.2052-6113http://hdl.handle.net/11449/13139310.1136/vetreco-2014-000072PMC4567150.pdf26392893PMC4567150PubMedreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengVeterinary Record Openinfo:eu-repo/semantics/openAccess2024-04-12T13:07:00Zoai:repositorio.unesp.br:11449/131393Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T18:56:44.745837Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Endectocide activity of a pour-on formulation containing 1.5 per cent ivermectin +0.5 per cent abamectin in cattle
title Endectocide activity of a pour-on formulation containing 1.5 per cent ivermectin +0.5 per cent abamectin in cattle
spellingShingle Endectocide activity of a pour-on formulation containing 1.5 per cent ivermectin +0.5 per cent abamectin in cattle
Silva, Heloisa Cristina [UNESP]
Cattle
Dermatobia hominis
Abamectin
Ivermectin
title_short Endectocide activity of a pour-on formulation containing 1.5 per cent ivermectin +0.5 per cent abamectin in cattle
title_full Endectocide activity of a pour-on formulation containing 1.5 per cent ivermectin +0.5 per cent abamectin in cattle
title_fullStr Endectocide activity of a pour-on formulation containing 1.5 per cent ivermectin +0.5 per cent abamectin in cattle
title_full_unstemmed Endectocide activity of a pour-on formulation containing 1.5 per cent ivermectin +0.5 per cent abamectin in cattle
title_sort Endectocide activity of a pour-on formulation containing 1.5 per cent ivermectin +0.5 per cent abamectin in cattle
author Silva, Heloisa Cristina [UNESP]
author_facet Silva, Heloisa Cristina [UNESP]
Prette, Nancy [UNESP]
Lopes, Welber Daniel Zanetti [UNESP]
Sakamoto, Cláudio Alessandro M [UNESP]
Buzzulini, Carolina [UNESP]
Dos Santos, Thais Rabelo [UNESP]
Cruz, Breno Cayeiro [UNESP]
Teixeira, Weslen F Pires [UNESP]
Felippelli, Gustavo [UNESP]
Carvalho, Rafael Silveira
Maciel, Willian Giquelin [UNESP]
Soares, Vando Edésio [UNESP]
da Costa, Alvimar José [UNESP]
author_role author
author2 Prette, Nancy [UNESP]
Lopes, Welber Daniel Zanetti [UNESP]
Sakamoto, Cláudio Alessandro M [UNESP]
Buzzulini, Carolina [UNESP]
Dos Santos, Thais Rabelo [UNESP]
Cruz, Breno Cayeiro [UNESP]
Teixeira, Weslen F Pires [UNESP]
Felippelli, Gustavo [UNESP]
Carvalho, Rafael Silveira
Maciel, Willian Giquelin [UNESP]
Soares, Vando Edésio [UNESP]
da Costa, Alvimar José [UNESP]
author2_role author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
Universidade Federal da Bahia (UFBA)
Universidade Federal da Paraíba (UFPB)
dc.contributor.author.fl_str_mv Silva, Heloisa Cristina [UNESP]
Prette, Nancy [UNESP]
Lopes, Welber Daniel Zanetti [UNESP]
Sakamoto, Cláudio Alessandro M [UNESP]
Buzzulini, Carolina [UNESP]
Dos Santos, Thais Rabelo [UNESP]
Cruz, Breno Cayeiro [UNESP]
Teixeira, Weslen F Pires [UNESP]
Felippelli, Gustavo [UNESP]
Carvalho, Rafael Silveira
Maciel, Willian Giquelin [UNESP]
Soares, Vando Edésio [UNESP]
da Costa, Alvimar José [UNESP]
dc.subject.por.fl_str_mv Cattle
Dermatobia hominis
Abamectin
Ivermectin
topic Cattle
Dermatobia hominis
Abamectin
Ivermectin
description The present work aimed to evaluate, through ten different studies, the therapeutic efficacy of a new pour-on formulation, containing 1.5 per cent ivermectin +0.5 per cent abamectin, against parasites of cattle. Results obtained on trials against Rhipicephalus (Boophilus) microplus showed that the pour-on combination of 1.5 per cent ivermectin +0.5 per cent abamectin obtained superior efficacy indexes against this ectoparasite, when compared with formulations containing 0.5 per cent ivermectin, 1 per cent ivermectin and the combination of 1 per cent abamectin +20 per cent levamisole. The results of efficacy of the ivermectin+abamectin and the 0.5 per cent ivermectin against Haematobia irritans were similar. Against Cochliomyia hominivorax larvae, all pour-on formulations tested (1.5 per cent ivermectin +0.5 per cent abamectin, 0.5 per cent ivermectin and 0.5 per cent abamectin), as well as 1 per cent doramectin administered subcutaneously, were considered ineffective. Cattle medicated with 1.5 per cent ivermectin +0.5 per cent abamectin, pour-on, remained free from parasitism by Dermatobia hominis larvae during 42 days (96 per cent efficacy), while values superior to 90 per cent were obtained by 0.5 per cent ivermectin (92 per cent) and 0.5 per cent abamectin (93 per cent) until the 42nd and 35th days post treatment, respectively. Against Haemonchus placei and Oesophagostomum radiatum, the pour-on of ivermectin+abamectin showed better efficacy than the 0.5 per cent ivermectin and 0.5 per cent abamectin. As to Cooperia punctata, there was no difference regarding efficacy results obtained by the avermectins combination and abamectin. The pour-on combination of 1.5 per cent ivermectin +0.5 per cent abamectin obtained high efficacy against R. (B.) microplus, D. hominis and some species of cattle gastrointestinal helminths when compared with formulations of 0.5 per cent ivermectin and 0.5 per cent abamectin administered through the same route.
publishDate 2015
dc.date.none.fl_str_mv 2015-12-07T15:34:45Z
2015-12-07T15:34:45Z
2015
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1136/vetreco-2014-000072
Veterinary Record Open, v. 2, n. 1, p. 1-12, 2015.
2052-6113
http://hdl.handle.net/11449/131393
10.1136/vetreco-2014-000072
PMC4567150.pdf
26392893
PMC4567150
url http://dx.doi.org/10.1136/vetreco-2014-000072
http://hdl.handle.net/11449/131393
identifier_str_mv Veterinary Record Open, v. 2, n. 1, p. 1-12, 2015.
2052-6113
10.1136/vetreco-2014-000072
PMC4567150.pdf
26392893
PMC4567150
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Veterinary Record Open
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1-12
application/pdf
dc.publisher.none.fl_str_mv BMJ Publishing Group Limited
publisher.none.fl_str_mv BMJ Publishing Group Limited
dc.source.none.fl_str_mv PubMed
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
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