Mechanical-physicochemical properties and biocompatibility of catechin-incorporated adhesive resins

Detalhes bibliográficos
Autor(a) principal: Fonseca, Beatriz Maria [UNESP]
Data de Publicação: 2019
Outros Autores: Barcellos, Daphne Camara [UNESP], Silva, Tânia Mara da [UNESP], Borges, Alexandre Luis Souto [UNESP], Cavalcanti, Bruno das Neves, Prakki, Anuradha, Oliveira, Hueder Paulo Moisés de, Gonçalves, Sérgio Eduardo de Paiva [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/1678-7757-2018-0111
http://hdl.handle.net/11449/188599
Resumo: Several anti-proteolytic dentin therapies are being exhaustively studied in an attempt to reduce dentin bond degradation and improve clinical performance and longevity of adhesive restorations. Objectives: This study assessed the effect of epigallocatechin-3-gallate (EGCG) on long-term bond strength when incorporated into adhesives. Material and Methods: Adhesive systems were formulated with EGCG concentrations of 0 wt%: (no EGCG; control); 0.5 wt% EGCG; 1.0 wt% EGCG, and 1.5 wt% EGCG. Flexural strength (FS), modulus of elasticity (ME), modulus of resilience (MR), compressive strength (CS), degree of conversion (DC), polymerization shrinkage (PS), percentage of water sorption (%WS), percentage of water solubility (%WL) and cytotoxicity properties were tested. Dentin microtensile bond strength (µTBS) was evaluated after 24 h and again after 6 months of water storage. The adhesive interface was analyzed using scanning electron microscopy (SEM). Results: No significant differences were found among the groups in terms of FS, ME, MR, CS and PS. EGCG-doped adhesives increased the DC relative to the control group. EGCG concentrations of 1.0 wt% and 0.5 wt% decreased the WS of adhesives. WL decreased in all cases in which EGCG was added to adhesives, regardless of the concentration. EGCG concentrations of 1.0 wt% and 0.5 wt% reduced cytotoxicity. EGCG concentrations of 1.0 wt% and 0.5 wt% preserved µTBS after 6 months of storage, while 1.5 wt% EGCG significantly decreased µTBS. SEM: the integrity of the hybrid layer was maintained in the 0.5 wt% and 1.0 wt% EGCG groups. Conclusion: EGCG concentrations of 1.0 wt% and 0.5 wt% showed better biological and mechanical performance, preserved bond strength and adhesive interface, and reduced cytotoxicity.
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spelling Mechanical-physicochemical properties and biocompatibility of catechin-incorporated adhesive resinsCatechinCollagenDental adhesivesDentin-bonding agentsSeveral anti-proteolytic dentin therapies are being exhaustively studied in an attempt to reduce dentin bond degradation and improve clinical performance and longevity of adhesive restorations. Objectives: This study assessed the effect of epigallocatechin-3-gallate (EGCG) on long-term bond strength when incorporated into adhesives. Material and Methods: Adhesive systems were formulated with EGCG concentrations of 0 wt%: (no EGCG; control); 0.5 wt% EGCG; 1.0 wt% EGCG, and 1.5 wt% EGCG. Flexural strength (FS), modulus of elasticity (ME), modulus of resilience (MR), compressive strength (CS), degree of conversion (DC), polymerization shrinkage (PS), percentage of water sorption (%WS), percentage of water solubility (%WL) and cytotoxicity properties were tested. Dentin microtensile bond strength (µTBS) was evaluated after 24 h and again after 6 months of water storage. The adhesive interface was analyzed using scanning electron microscopy (SEM). Results: No significant differences were found among the groups in terms of FS, ME, MR, CS and PS. EGCG-doped adhesives increased the DC relative to the control group. EGCG concentrations of 1.0 wt% and 0.5 wt% decreased the WS of adhesives. WL decreased in all cases in which EGCG was added to adhesives, regardless of the concentration. EGCG concentrations of 1.0 wt% and 0.5 wt% reduced cytotoxicity. EGCG concentrations of 1.0 wt% and 0.5 wt% preserved µTBS after 6 months of storage, while 1.5 wt% EGCG significantly decreased µTBS. SEM: the integrity of the hybrid layer was maintained in the 0.5 wt% and 1.0 wt% EGCG groups. Conclusion: EGCG concentrations of 1.0 wt% and 0.5 wt% showed better biological and mechanical performance, preserved bond strength and adhesive interface, and reduced cytotoxicity.Universidade Estadual Paulista (UNESP) Instituto de Ciência e Tecnologia Departamento de Odontologia Restauradora Grupo Acadêmico de Pesquisa ClínicaUniversity of Iowa College of Dentistry and Dental Clinics Department of EndodonticsUniversity of Toronto Faculty of Dentistry Restorative DepartmentCentro de Ciências Naturais e Humanas Universidade Federal do ABCUniversidade Estadual Paulista (UNESP) Instituto de Ciência e Tecnologia Departamento de Odontologia Restauradora Grupo Acadêmico de Pesquisa ClínicaUniversidade Estadual Paulista (Unesp)College of Dentistry and Dental ClinicsRestorative DepartmentUniversidade Federal do ABC (UFABC)Fonseca, Beatriz Maria [UNESP]Barcellos, Daphne Camara [UNESP]Silva, Tânia Mara da [UNESP]Borges, Alexandre Luis Souto [UNESP]Cavalcanti, Bruno das NevesPrakki, AnuradhaOliveira, Hueder Paulo Moisés deGonçalves, Sérgio Eduardo de Paiva [UNESP]2019-10-06T16:13:18Z2019-10-06T16:13:18Z2019-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://dx.doi.org/10.1590/1678-7757-2018-0111Journal of Applied Oral Science, v. 27.1678-77651678-7757http://hdl.handle.net/11449/18859910.1590/1678-7757-2018-0111S1678-775720190001004182-s2.0-85059798345S1678-77572019000100418.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Applied Oral Scienceinfo:eu-repo/semantics/openAccess2023-10-19T06:09:18Zoai:repositorio.unesp.br:11449/188599Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T15:22:18.701607Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Mechanical-physicochemical properties and biocompatibility of catechin-incorporated adhesive resins
title Mechanical-physicochemical properties and biocompatibility of catechin-incorporated adhesive resins
spellingShingle Mechanical-physicochemical properties and biocompatibility of catechin-incorporated adhesive resins
Fonseca, Beatriz Maria [UNESP]
Catechin
Collagen
Dental adhesives
Dentin-bonding agents
title_short Mechanical-physicochemical properties and biocompatibility of catechin-incorporated adhesive resins
title_full Mechanical-physicochemical properties and biocompatibility of catechin-incorporated adhesive resins
title_fullStr Mechanical-physicochemical properties and biocompatibility of catechin-incorporated adhesive resins
title_full_unstemmed Mechanical-physicochemical properties and biocompatibility of catechin-incorporated adhesive resins
title_sort Mechanical-physicochemical properties and biocompatibility of catechin-incorporated adhesive resins
author Fonseca, Beatriz Maria [UNESP]
author_facet Fonseca, Beatriz Maria [UNESP]
Barcellos, Daphne Camara [UNESP]
Silva, Tânia Mara da [UNESP]
Borges, Alexandre Luis Souto [UNESP]
Cavalcanti, Bruno das Neves
Prakki, Anuradha
Oliveira, Hueder Paulo Moisés de
Gonçalves, Sérgio Eduardo de Paiva [UNESP]
author_role author
author2 Barcellos, Daphne Camara [UNESP]
Silva, Tânia Mara da [UNESP]
Borges, Alexandre Luis Souto [UNESP]
Cavalcanti, Bruno das Neves
Prakki, Anuradha
Oliveira, Hueder Paulo Moisés de
Gonçalves, Sérgio Eduardo de Paiva [UNESP]
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
College of Dentistry and Dental Clinics
Restorative Department
Universidade Federal do ABC (UFABC)
dc.contributor.author.fl_str_mv Fonseca, Beatriz Maria [UNESP]
Barcellos, Daphne Camara [UNESP]
Silva, Tânia Mara da [UNESP]
Borges, Alexandre Luis Souto [UNESP]
Cavalcanti, Bruno das Neves
Prakki, Anuradha
Oliveira, Hueder Paulo Moisés de
Gonçalves, Sérgio Eduardo de Paiva [UNESP]
dc.subject.por.fl_str_mv Catechin
Collagen
Dental adhesives
Dentin-bonding agents
topic Catechin
Collagen
Dental adhesives
Dentin-bonding agents
description Several anti-proteolytic dentin therapies are being exhaustively studied in an attempt to reduce dentin bond degradation and improve clinical performance and longevity of adhesive restorations. Objectives: This study assessed the effect of epigallocatechin-3-gallate (EGCG) on long-term bond strength when incorporated into adhesives. Material and Methods: Adhesive systems were formulated with EGCG concentrations of 0 wt%: (no EGCG; control); 0.5 wt% EGCG; 1.0 wt% EGCG, and 1.5 wt% EGCG. Flexural strength (FS), modulus of elasticity (ME), modulus of resilience (MR), compressive strength (CS), degree of conversion (DC), polymerization shrinkage (PS), percentage of water sorption (%WS), percentage of water solubility (%WL) and cytotoxicity properties were tested. Dentin microtensile bond strength (µTBS) was evaluated after 24 h and again after 6 months of water storage. The adhesive interface was analyzed using scanning electron microscopy (SEM). Results: No significant differences were found among the groups in terms of FS, ME, MR, CS and PS. EGCG-doped adhesives increased the DC relative to the control group. EGCG concentrations of 1.0 wt% and 0.5 wt% decreased the WS of adhesives. WL decreased in all cases in which EGCG was added to adhesives, regardless of the concentration. EGCG concentrations of 1.0 wt% and 0.5 wt% reduced cytotoxicity. EGCG concentrations of 1.0 wt% and 0.5 wt% preserved µTBS after 6 months of storage, while 1.5 wt% EGCG significantly decreased µTBS. SEM: the integrity of the hybrid layer was maintained in the 0.5 wt% and 1.0 wt% EGCG groups. Conclusion: EGCG concentrations of 1.0 wt% and 0.5 wt% showed better biological and mechanical performance, preserved bond strength and adhesive interface, and reduced cytotoxicity.
publishDate 2019
dc.date.none.fl_str_mv 2019-10-06T16:13:18Z
2019-10-06T16:13:18Z
2019-01-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/1678-7757-2018-0111
Journal of Applied Oral Science, v. 27.
1678-7765
1678-7757
http://hdl.handle.net/11449/188599
10.1590/1678-7757-2018-0111
S1678-77572019000100418
2-s2.0-85059798345
S1678-77572019000100418.pdf
url http://dx.doi.org/10.1590/1678-7757-2018-0111
http://hdl.handle.net/11449/188599
identifier_str_mv Journal of Applied Oral Science, v. 27.
1678-7765
1678-7757
10.1590/1678-7757-2018-0111
S1678-77572019000100418
2-s2.0-85059798345
S1678-77572019000100418.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Journal of Applied Oral Science
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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