Mechanical-physicochemical properties and biocompatibility of catechin-incorporated adhesive resins
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/1678-7757-2018-0111 http://hdl.handle.net/11449/188599 |
Resumo: | Several anti-proteolytic dentin therapies are being exhaustively studied in an attempt to reduce dentin bond degradation and improve clinical performance and longevity of adhesive restorations. Objectives: This study assessed the effect of epigallocatechin-3-gallate (EGCG) on long-term bond strength when incorporated into adhesives. Material and Methods: Adhesive systems were formulated with EGCG concentrations of 0 wt%: (no EGCG; control); 0.5 wt% EGCG; 1.0 wt% EGCG, and 1.5 wt% EGCG. Flexural strength (FS), modulus of elasticity (ME), modulus of resilience (MR), compressive strength (CS), degree of conversion (DC), polymerization shrinkage (PS), percentage of water sorption (%WS), percentage of water solubility (%WL) and cytotoxicity properties were tested. Dentin microtensile bond strength (µTBS) was evaluated after 24 h and again after 6 months of water storage. The adhesive interface was analyzed using scanning electron microscopy (SEM). Results: No significant differences were found among the groups in terms of FS, ME, MR, CS and PS. EGCG-doped adhesives increased the DC relative to the control group. EGCG concentrations of 1.0 wt% and 0.5 wt% decreased the WS of adhesives. WL decreased in all cases in which EGCG was added to adhesives, regardless of the concentration. EGCG concentrations of 1.0 wt% and 0.5 wt% reduced cytotoxicity. EGCG concentrations of 1.0 wt% and 0.5 wt% preserved µTBS after 6 months of storage, while 1.5 wt% EGCG significantly decreased µTBS. SEM: the integrity of the hybrid layer was maintained in the 0.5 wt% and 1.0 wt% EGCG groups. Conclusion: EGCG concentrations of 1.0 wt% and 0.5 wt% showed better biological and mechanical performance, preserved bond strength and adhesive interface, and reduced cytotoxicity. |
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Mechanical-physicochemical properties and biocompatibility of catechin-incorporated adhesive resinsCatechinCollagenDental adhesivesDentin-bonding agentsSeveral anti-proteolytic dentin therapies are being exhaustively studied in an attempt to reduce dentin bond degradation and improve clinical performance and longevity of adhesive restorations. Objectives: This study assessed the effect of epigallocatechin-3-gallate (EGCG) on long-term bond strength when incorporated into adhesives. Material and Methods: Adhesive systems were formulated with EGCG concentrations of 0 wt%: (no EGCG; control); 0.5 wt% EGCG; 1.0 wt% EGCG, and 1.5 wt% EGCG. Flexural strength (FS), modulus of elasticity (ME), modulus of resilience (MR), compressive strength (CS), degree of conversion (DC), polymerization shrinkage (PS), percentage of water sorption (%WS), percentage of water solubility (%WL) and cytotoxicity properties were tested. Dentin microtensile bond strength (µTBS) was evaluated after 24 h and again after 6 months of water storage. The adhesive interface was analyzed using scanning electron microscopy (SEM). Results: No significant differences were found among the groups in terms of FS, ME, MR, CS and PS. EGCG-doped adhesives increased the DC relative to the control group. EGCG concentrations of 1.0 wt% and 0.5 wt% decreased the WS of adhesives. WL decreased in all cases in which EGCG was added to adhesives, regardless of the concentration. EGCG concentrations of 1.0 wt% and 0.5 wt% reduced cytotoxicity. EGCG concentrations of 1.0 wt% and 0.5 wt% preserved µTBS after 6 months of storage, while 1.5 wt% EGCG significantly decreased µTBS. SEM: the integrity of the hybrid layer was maintained in the 0.5 wt% and 1.0 wt% EGCG groups. Conclusion: EGCG concentrations of 1.0 wt% and 0.5 wt% showed better biological and mechanical performance, preserved bond strength and adhesive interface, and reduced cytotoxicity.Universidade Estadual Paulista (UNESP) Instituto de Ciência e Tecnologia Departamento de Odontologia Restauradora Grupo Acadêmico de Pesquisa ClínicaUniversity of Iowa College of Dentistry and Dental Clinics Department of EndodonticsUniversity of Toronto Faculty of Dentistry Restorative DepartmentCentro de Ciências Naturais e Humanas Universidade Federal do ABCUniversidade Estadual Paulista (UNESP) Instituto de Ciência e Tecnologia Departamento de Odontologia Restauradora Grupo Acadêmico de Pesquisa ClínicaUniversidade Estadual Paulista (Unesp)College of Dentistry and Dental ClinicsRestorative DepartmentUniversidade Federal do ABC (UFABC)Fonseca, Beatriz Maria [UNESP]Barcellos, Daphne Camara [UNESP]Silva, Tânia Mara da [UNESP]Borges, Alexandre Luis Souto [UNESP]Cavalcanti, Bruno das NevesPrakki, AnuradhaOliveira, Hueder Paulo Moisés deGonçalves, Sérgio Eduardo de Paiva [UNESP]2019-10-06T16:13:18Z2019-10-06T16:13:18Z2019-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://dx.doi.org/10.1590/1678-7757-2018-0111Journal of Applied Oral Science, v. 27.1678-77651678-7757http://hdl.handle.net/11449/18859910.1590/1678-7757-2018-0111S1678-775720190001004182-s2.0-85059798345S1678-77572019000100418.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Applied Oral Scienceinfo:eu-repo/semantics/openAccess2023-10-19T06:09:18Zoai:repositorio.unesp.br:11449/188599Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T15:22:18.701607Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Mechanical-physicochemical properties and biocompatibility of catechin-incorporated adhesive resins |
title |
Mechanical-physicochemical properties and biocompatibility of catechin-incorporated adhesive resins |
spellingShingle |
Mechanical-physicochemical properties and biocompatibility of catechin-incorporated adhesive resins Fonseca, Beatriz Maria [UNESP] Catechin Collagen Dental adhesives Dentin-bonding agents |
title_short |
Mechanical-physicochemical properties and biocompatibility of catechin-incorporated adhesive resins |
title_full |
Mechanical-physicochemical properties and biocompatibility of catechin-incorporated adhesive resins |
title_fullStr |
Mechanical-physicochemical properties and biocompatibility of catechin-incorporated adhesive resins |
title_full_unstemmed |
Mechanical-physicochemical properties and biocompatibility of catechin-incorporated adhesive resins |
title_sort |
Mechanical-physicochemical properties and biocompatibility of catechin-incorporated adhesive resins |
author |
Fonseca, Beatriz Maria [UNESP] |
author_facet |
Fonseca, Beatriz Maria [UNESP] Barcellos, Daphne Camara [UNESP] Silva, Tânia Mara da [UNESP] Borges, Alexandre Luis Souto [UNESP] Cavalcanti, Bruno das Neves Prakki, Anuradha Oliveira, Hueder Paulo Moisés de Gonçalves, Sérgio Eduardo de Paiva [UNESP] |
author_role |
author |
author2 |
Barcellos, Daphne Camara [UNESP] Silva, Tânia Mara da [UNESP] Borges, Alexandre Luis Souto [UNESP] Cavalcanti, Bruno das Neves Prakki, Anuradha Oliveira, Hueder Paulo Moisés de Gonçalves, Sérgio Eduardo de Paiva [UNESP] |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) College of Dentistry and Dental Clinics Restorative Department Universidade Federal do ABC (UFABC) |
dc.contributor.author.fl_str_mv |
Fonseca, Beatriz Maria [UNESP] Barcellos, Daphne Camara [UNESP] Silva, Tânia Mara da [UNESP] Borges, Alexandre Luis Souto [UNESP] Cavalcanti, Bruno das Neves Prakki, Anuradha Oliveira, Hueder Paulo Moisés de Gonçalves, Sérgio Eduardo de Paiva [UNESP] |
dc.subject.por.fl_str_mv |
Catechin Collagen Dental adhesives Dentin-bonding agents |
topic |
Catechin Collagen Dental adhesives Dentin-bonding agents |
description |
Several anti-proteolytic dentin therapies are being exhaustively studied in an attempt to reduce dentin bond degradation and improve clinical performance and longevity of adhesive restorations. Objectives: This study assessed the effect of epigallocatechin-3-gallate (EGCG) on long-term bond strength when incorporated into adhesives. Material and Methods: Adhesive systems were formulated with EGCG concentrations of 0 wt%: (no EGCG; control); 0.5 wt% EGCG; 1.0 wt% EGCG, and 1.5 wt% EGCG. Flexural strength (FS), modulus of elasticity (ME), modulus of resilience (MR), compressive strength (CS), degree of conversion (DC), polymerization shrinkage (PS), percentage of water sorption (%WS), percentage of water solubility (%WL) and cytotoxicity properties were tested. Dentin microtensile bond strength (µTBS) was evaluated after 24 h and again after 6 months of water storage. The adhesive interface was analyzed using scanning electron microscopy (SEM). Results: No significant differences were found among the groups in terms of FS, ME, MR, CS and PS. EGCG-doped adhesives increased the DC relative to the control group. EGCG concentrations of 1.0 wt% and 0.5 wt% decreased the WS of adhesives. WL decreased in all cases in which EGCG was added to adhesives, regardless of the concentration. EGCG concentrations of 1.0 wt% and 0.5 wt% reduced cytotoxicity. EGCG concentrations of 1.0 wt% and 0.5 wt% preserved µTBS after 6 months of storage, while 1.5 wt% EGCG significantly decreased µTBS. SEM: the integrity of the hybrid layer was maintained in the 0.5 wt% and 1.0 wt% EGCG groups. Conclusion: EGCG concentrations of 1.0 wt% and 0.5 wt% showed better biological and mechanical performance, preserved bond strength and adhesive interface, and reduced cytotoxicity. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-10-06T16:13:18Z 2019-10-06T16:13:18Z 2019-01-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/1678-7757-2018-0111 Journal of Applied Oral Science, v. 27. 1678-7765 1678-7757 http://hdl.handle.net/11449/188599 10.1590/1678-7757-2018-0111 S1678-77572019000100418 2-s2.0-85059798345 S1678-77572019000100418.pdf |
url |
http://dx.doi.org/10.1590/1678-7757-2018-0111 http://hdl.handle.net/11449/188599 |
identifier_str_mv |
Journal of Applied Oral Science, v. 27. 1678-7765 1678-7757 10.1590/1678-7757-2018-0111 S1678-77572019000100418 2-s2.0-85059798345 S1678-77572019000100418.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Applied Oral Science |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
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1808128503931994112 |