Metabolomics Reveals a 26-Membered Macrolactone Produced by Endophytic Colletotrichum spp. from Alcatrazes Island, Brazil

Detalhes bibliográficos
Autor(a) principal: Takaki, Mirelle
Data de Publicação: 2022
Outros Autores: Williams, David E., Freire, Vitor F., Sartori, Sérgio B., Lira, Simone P., Bizarria, Rodolfo [UNESP], Rodrigues, Andre [UNESP], Gonçalves Da Costa, Danielle R., Amorim, Marcelo R., Ferreira, Antonio G., Andersen, Raymond J., Linington, Roger G., Berlinck, Roberto G. S.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1021/acs.orglett.2c03531
http://hdl.handle.net/11449/246497
Resumo: Comparative metabolomics analysis of nonphytotoxic endophytic Colletotrichum spp. isolated from Anthurium alcatrazense endemic to Alcatrazes island (Brazil) and phytopathogenic Colletotrichum spp. isolated from the mainland of Brazil revealed significant differences in chemical composition. Examination of endophytic Colletotrichum spp. from Alcatrazes island led to the discovery of a 26-member macrolactone, colletotrichumolide (1), containing a phosphatidyl choline side chain. Further examination of the phytopathogenic strains from the mainland identified a family of phytopathogenic metabolites not present in the nonpathogenic island-derived strains, suggesting that geographical isolation could influence the secondary metabolism of fungal strains.
id UNSP_80c6663aa3bde9d2b92092edde1871bf
oai_identifier_str oai:repositorio.unesp.br:11449/246497
network_acronym_str UNSP
network_name_str Repositório Institucional da UNESP
repository_id_str 2946
spelling Metabolomics Reveals a 26-Membered Macrolactone Produced by Endophytic Colletotrichum spp. from Alcatrazes Island, BrazilComparative metabolomics analysis of nonphytotoxic endophytic Colletotrichum spp. isolated from Anthurium alcatrazense endemic to Alcatrazes island (Brazil) and phytopathogenic Colletotrichum spp. isolated from the mainland of Brazil revealed significant differences in chemical composition. Examination of endophytic Colletotrichum spp. from Alcatrazes island led to the discovery of a 26-member macrolactone, colletotrichumolide (1), containing a phosphatidyl choline side chain. Further examination of the phytopathogenic strains from the mainland identified a family of phytopathogenic metabolites not present in the nonpathogenic island-derived strains, suggesting that geographical isolation could influence the secondary metabolism of fungal strains.Instituto de Química de São Carlos Universidade de São Paulo, CP 780, SPDepartment of Chemistry Simon Fraser UniversityDepartment of Chemistry Department of Earth Ocean & Atmospheric Sciences University of British ColumbiaDepartamento de Ciências Exatas Escola Superior de Agricultura Luiz de Queiroz Universidade de Sâo Paulo, Avenida Pádua Dias, 11, CP 9, Agronomia, SPDepartamento de Biologia Geral e Aplicada Universidade Estadual Paulista (UNESP), SPDepartamento de Química Universidade Federal de São Carlos, SPDepartamento de Biologia Geral e Aplicada Universidade Estadual Paulista (UNESP), SPUniversidade de São Paulo (USP)Simon Fraser UniversityUniversity of British ColumbiaUniversidade de Sâo PauloUniversidade Estadual Paulista (UNESP)Universidade Federal de São Carlos (UFSCar)Takaki, MirelleWilliams, David E.Freire, Vitor F.Sartori, Sérgio B.Lira, Simone P.Bizarria, Rodolfo [UNESP]Rodrigues, Andre [UNESP]Gonçalves Da Costa, Danielle R.Amorim, Marcelo R.Ferreira, Antonio G.Andersen, Raymond J.Linington, Roger G.Berlinck, Roberto G. S.2023-07-29T12:42:31Z2023-07-29T12:42:31Z2022-12-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article9381-9385http://dx.doi.org/10.1021/acs.orglett.2c03531Organic Letters, v. 24, n. 51, p. 9381-9385, 2022.1523-70521523-7060http://hdl.handle.net/11449/24649710.1021/acs.orglett.2c035312-s2.0-85144330931Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengOrganic Lettersinfo:eu-repo/semantics/openAccess2023-07-29T12:42:31Zoai:repositorio.unesp.br:11449/246497Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T17:43:17.655713Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Metabolomics Reveals a 26-Membered Macrolactone Produced by Endophytic Colletotrichum spp. from Alcatrazes Island, Brazil
title Metabolomics Reveals a 26-Membered Macrolactone Produced by Endophytic Colletotrichum spp. from Alcatrazes Island, Brazil
spellingShingle Metabolomics Reveals a 26-Membered Macrolactone Produced by Endophytic Colletotrichum spp. from Alcatrazes Island, Brazil
Takaki, Mirelle
title_short Metabolomics Reveals a 26-Membered Macrolactone Produced by Endophytic Colletotrichum spp. from Alcatrazes Island, Brazil
title_full Metabolomics Reveals a 26-Membered Macrolactone Produced by Endophytic Colletotrichum spp. from Alcatrazes Island, Brazil
title_fullStr Metabolomics Reveals a 26-Membered Macrolactone Produced by Endophytic Colletotrichum spp. from Alcatrazes Island, Brazil
title_full_unstemmed Metabolomics Reveals a 26-Membered Macrolactone Produced by Endophytic Colletotrichum spp. from Alcatrazes Island, Brazil
title_sort Metabolomics Reveals a 26-Membered Macrolactone Produced by Endophytic Colletotrichum spp. from Alcatrazes Island, Brazil
author Takaki, Mirelle
author_facet Takaki, Mirelle
Williams, David E.
Freire, Vitor F.
Sartori, Sérgio B.
Lira, Simone P.
Bizarria, Rodolfo [UNESP]
Rodrigues, Andre [UNESP]
Gonçalves Da Costa, Danielle R.
Amorim, Marcelo R.
Ferreira, Antonio G.
Andersen, Raymond J.
Linington, Roger G.
Berlinck, Roberto G. S.
author_role author
author2 Williams, David E.
Freire, Vitor F.
Sartori, Sérgio B.
Lira, Simone P.
Bizarria, Rodolfo [UNESP]
Rodrigues, Andre [UNESP]
Gonçalves Da Costa, Danielle R.
Amorim, Marcelo R.
Ferreira, Antonio G.
Andersen, Raymond J.
Linington, Roger G.
Berlinck, Roberto G. S.
author2_role author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade de São Paulo (USP)
Simon Fraser University
University of British Columbia
Universidade de Sâo Paulo
Universidade Estadual Paulista (UNESP)
Universidade Federal de São Carlos (UFSCar)
dc.contributor.author.fl_str_mv Takaki, Mirelle
Williams, David E.
Freire, Vitor F.
Sartori, Sérgio B.
Lira, Simone P.
Bizarria, Rodolfo [UNESP]
Rodrigues, Andre [UNESP]
Gonçalves Da Costa, Danielle R.
Amorim, Marcelo R.
Ferreira, Antonio G.
Andersen, Raymond J.
Linington, Roger G.
Berlinck, Roberto G. S.
description Comparative metabolomics analysis of nonphytotoxic endophytic Colletotrichum spp. isolated from Anthurium alcatrazense endemic to Alcatrazes island (Brazil) and phytopathogenic Colletotrichum spp. isolated from the mainland of Brazil revealed significant differences in chemical composition. Examination of endophytic Colletotrichum spp. from Alcatrazes island led to the discovery of a 26-member macrolactone, colletotrichumolide (1), containing a phosphatidyl choline side chain. Further examination of the phytopathogenic strains from the mainland identified a family of phytopathogenic metabolites not present in the nonpathogenic island-derived strains, suggesting that geographical isolation could influence the secondary metabolism of fungal strains.
publishDate 2022
dc.date.none.fl_str_mv 2022-12-30
2023-07-29T12:42:31Z
2023-07-29T12:42:31Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1021/acs.orglett.2c03531
Organic Letters, v. 24, n. 51, p. 9381-9385, 2022.
1523-7052
1523-7060
http://hdl.handle.net/11449/246497
10.1021/acs.orglett.2c03531
2-s2.0-85144330931
url http://dx.doi.org/10.1021/acs.orglett.2c03531
http://hdl.handle.net/11449/246497
identifier_str_mv Organic Letters, v. 24, n. 51, p. 9381-9385, 2022.
1523-7052
1523-7060
10.1021/acs.orglett.2c03531
2-s2.0-85144330931
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Organic Letters
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 9381-9385
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808128849741873152

Registros relacionados