Microencapsulated sodium butyrate on the intestinal integrity of broilers challenged with Eimeria spp.
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.livsci.2023.105209 http://hdl.handle.net/11449/249815 |
Resumo: | To explore the effect of microencapsulated sodium butyrate (MSB) on the performance, intestinal morphometry, intestinal goblet cell count, cellular turnover of the intestinal mucosa, oocyst count per gram of feces (OPG), and small intestine lesion score of broilers challenged with Eimeria spp., 1,200 Ross® male broiler chicks were distributed in a completely randomized design, with five treatments and six replications, and reared for 42 days. At 16 D-old, the birds were inoculated orally with 0.5 ml of a solution containing an Eimeria spp. pool and the treatments consisted of NC: negative control, basal diet (BD); 1,000 MSB: BD + 1,000 mg/kg MSB; 1,500 MSB: BD + 1,500 mg/kg MSB; 2,000 MSB: BD + 2,000 mg/kg MSB; PC: positive control, BD + avilamycin. No statistical differences were observed for the variables performance, intestinal morphometry or intestinal goblet cell count during the experiment. In the OPG and lesion score, a difference was observed only for periods of collection, in which greater excretion was detected seven days post-inoculation. The lesions caused by E. acervulina and E. tenella were attenuated 10- and 8-days post-inoculation, respectively and the largest lesions caused by E. maxima were observed five days post-inoculation. In the period 0–21 days, the treatments receiving MSB or antibiotic presented greater cellular turnover of the intestinal mucosa. In the period 22–42 days, the treatments with inclusion of 1,500 mg/kg MSB and 2,000 mg/kg MSB and PC showed lower cell turnover of the intestinal mucosa, indicating that MSB was able to protect the intestinal mucosa. It is concluded based turnover results that MSB benefits the intestinal development in the starter phase, and it is similar to the antibiotic in terms of preservation of the post-challenge intestinal mucosa. |
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Microencapsulated sodium butyrate on the intestinal integrity of broilers challenged with Eimeria spp.Butyric acidIntestinal morphologyIntestinal turnoverMicroencapsulationStable isotopesTo explore the effect of microencapsulated sodium butyrate (MSB) on the performance, intestinal morphometry, intestinal goblet cell count, cellular turnover of the intestinal mucosa, oocyst count per gram of feces (OPG), and small intestine lesion score of broilers challenged with Eimeria spp., 1,200 Ross® male broiler chicks were distributed in a completely randomized design, with five treatments and six replications, and reared for 42 days. At 16 D-old, the birds were inoculated orally with 0.5 ml of a solution containing an Eimeria spp. pool and the treatments consisted of NC: negative control, basal diet (BD); 1,000 MSB: BD + 1,000 mg/kg MSB; 1,500 MSB: BD + 1,500 mg/kg MSB; 2,000 MSB: BD + 2,000 mg/kg MSB; PC: positive control, BD + avilamycin. No statistical differences were observed for the variables performance, intestinal morphometry or intestinal goblet cell count during the experiment. In the OPG and lesion score, a difference was observed only for periods of collection, in which greater excretion was detected seven days post-inoculation. The lesions caused by E. acervulina and E. tenella were attenuated 10- and 8-days post-inoculation, respectively and the largest lesions caused by E. maxima were observed five days post-inoculation. In the period 0–21 days, the treatments receiving MSB or antibiotic presented greater cellular turnover of the intestinal mucosa. In the period 22–42 days, the treatments with inclusion of 1,500 mg/kg MSB and 2,000 mg/kg MSB and PC showed lower cell turnover of the intestinal mucosa, indicating that MSB was able to protect the intestinal mucosa. It is concluded based turnover results that MSB benefits the intestinal development in the starter phase, and it is similar to the antibiotic in terms of preservation of the post-challenge intestinal mucosa.São Paulo State University (Unesp) College of Technology and Agricultural Sciences Department of Animal Science, São PauloSão Paulo State University (Unesp) Institute of Biosciences Environmental Stable Isotopes Center, São PauloUniversity of São Paulo (Usp) Institute of Biomedical Sciences Department of Parasitology, São PauloSão Paulo State University (Unesp) College of Technology and Agricultural Sciences Department of Animal Science, São PauloSão Paulo State University (Unesp) Institute of Biosciences Environmental Stable Isotopes Center, São PauloUniversidade Estadual Paulista (UNESP)Universidade de São Paulo (USP)Lima, Gabrieli Andressa de [UNESP]Barbosa, Bárbara Fernanda da Silva [UNESP]Ventura, Gabriela [UNESP]Gonçalves, Izabela Mlaker [UNESP]Costa, Vladimir Eliodoro [UNESP]Polycarpo, Gustavo do Valle [UNESP]Madeira, Alda Maria Backx NoronhaCruz-Polycarpo, Valquíria Cação [UNESP]2023-07-29T16:09:59Z2023-07-29T16:09:59Z2023-04-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1016/j.livsci.2023.105209Livestock Science, v. 270.1871-1413http://hdl.handle.net/11449/24981510.1016/j.livsci.2023.1052092-s2.0-85151466643Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengLivestock Scienceinfo:eu-repo/semantics/openAccess2024-05-07T13:47:03Zoai:repositorio.unesp.br:11449/249815Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-05-07T13:47:03Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Microencapsulated sodium butyrate on the intestinal integrity of broilers challenged with Eimeria spp. |
title |
Microencapsulated sodium butyrate on the intestinal integrity of broilers challenged with Eimeria spp. |
spellingShingle |
Microencapsulated sodium butyrate on the intestinal integrity of broilers challenged with Eimeria spp. Lima, Gabrieli Andressa de [UNESP] Butyric acid Intestinal morphology Intestinal turnover Microencapsulation Stable isotopes |
title_short |
Microencapsulated sodium butyrate on the intestinal integrity of broilers challenged with Eimeria spp. |
title_full |
Microencapsulated sodium butyrate on the intestinal integrity of broilers challenged with Eimeria spp. |
title_fullStr |
Microencapsulated sodium butyrate on the intestinal integrity of broilers challenged with Eimeria spp. |
title_full_unstemmed |
Microencapsulated sodium butyrate on the intestinal integrity of broilers challenged with Eimeria spp. |
title_sort |
Microencapsulated sodium butyrate on the intestinal integrity of broilers challenged with Eimeria spp. |
author |
Lima, Gabrieli Andressa de [UNESP] |
author_facet |
Lima, Gabrieli Andressa de [UNESP] Barbosa, Bárbara Fernanda da Silva [UNESP] Ventura, Gabriela [UNESP] Gonçalves, Izabela Mlaker [UNESP] Costa, Vladimir Eliodoro [UNESP] Polycarpo, Gustavo do Valle [UNESP] Madeira, Alda Maria Backx Noronha Cruz-Polycarpo, Valquíria Cação [UNESP] |
author_role |
author |
author2 |
Barbosa, Bárbara Fernanda da Silva [UNESP] Ventura, Gabriela [UNESP] Gonçalves, Izabela Mlaker [UNESP] Costa, Vladimir Eliodoro [UNESP] Polycarpo, Gustavo do Valle [UNESP] Madeira, Alda Maria Backx Noronha Cruz-Polycarpo, Valquíria Cação [UNESP] |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) Universidade de São Paulo (USP) |
dc.contributor.author.fl_str_mv |
Lima, Gabrieli Andressa de [UNESP] Barbosa, Bárbara Fernanda da Silva [UNESP] Ventura, Gabriela [UNESP] Gonçalves, Izabela Mlaker [UNESP] Costa, Vladimir Eliodoro [UNESP] Polycarpo, Gustavo do Valle [UNESP] Madeira, Alda Maria Backx Noronha Cruz-Polycarpo, Valquíria Cação [UNESP] |
dc.subject.por.fl_str_mv |
Butyric acid Intestinal morphology Intestinal turnover Microencapsulation Stable isotopes |
topic |
Butyric acid Intestinal morphology Intestinal turnover Microencapsulation Stable isotopes |
description |
To explore the effect of microencapsulated sodium butyrate (MSB) on the performance, intestinal morphometry, intestinal goblet cell count, cellular turnover of the intestinal mucosa, oocyst count per gram of feces (OPG), and small intestine lesion score of broilers challenged with Eimeria spp., 1,200 Ross® male broiler chicks were distributed in a completely randomized design, with five treatments and six replications, and reared for 42 days. At 16 D-old, the birds were inoculated orally with 0.5 ml of a solution containing an Eimeria spp. pool and the treatments consisted of NC: negative control, basal diet (BD); 1,000 MSB: BD + 1,000 mg/kg MSB; 1,500 MSB: BD + 1,500 mg/kg MSB; 2,000 MSB: BD + 2,000 mg/kg MSB; PC: positive control, BD + avilamycin. No statistical differences were observed for the variables performance, intestinal morphometry or intestinal goblet cell count during the experiment. In the OPG and lesion score, a difference was observed only for periods of collection, in which greater excretion was detected seven days post-inoculation. The lesions caused by E. acervulina and E. tenella were attenuated 10- and 8-days post-inoculation, respectively and the largest lesions caused by E. maxima were observed five days post-inoculation. In the period 0–21 days, the treatments receiving MSB or antibiotic presented greater cellular turnover of the intestinal mucosa. In the period 22–42 days, the treatments with inclusion of 1,500 mg/kg MSB and 2,000 mg/kg MSB and PC showed lower cell turnover of the intestinal mucosa, indicating that MSB was able to protect the intestinal mucosa. It is concluded based turnover results that MSB benefits the intestinal development in the starter phase, and it is similar to the antibiotic in terms of preservation of the post-challenge intestinal mucosa. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-07-29T16:09:59Z 2023-07-29T16:09:59Z 2023-04-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.livsci.2023.105209 Livestock Science, v. 270. 1871-1413 http://hdl.handle.net/11449/249815 10.1016/j.livsci.2023.105209 2-s2.0-85151466643 |
url |
http://dx.doi.org/10.1016/j.livsci.2023.105209 http://hdl.handle.net/11449/249815 |
identifier_str_mv |
Livestock Science, v. 270. 1871-1413 10.1016/j.livsci.2023.105209 2-s2.0-85151466643 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Livestock Science |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1799964434515361792 |