Genomic analysis of the population structure in horses of the Brazilian Mangalarga Marchador breed
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.livsci.2019.09.010 http://hdl.handle.net/11449/189660 |
Resumo: | The Mangalarga Marchador is the Brazilian saddle horse. It has two characteristic gaits, marcha batida and marcha picada, that provide greater comfort to the rider during cavalcade and work. This horse breed is mainly used for work on beef cattle farms and different modalities of equestrian sports. The objective of this study was to characterize the linkage disequilibrium (LD), calculated by r², of Brazilian Mangalarga Marchador horses raised in Brazil using large-scale SNP genotyping. We also investigated the effective size (Ne) of the population, as well as its structure and relationships. A total of 240 Mangalarga Marchador horses of both sexes, registered with the Brazilian breeders association (ABCCMM), were used. The number of informative SNPs was 377,308. Principal component analysis showed that Mangalarga Marchador horses of the two different gait types belong to the same population, i.e., these groups did not segregate significantly within the breed. This finding should be taken into consideration in genetic population studies. The estimated genomic r² was 0.096 ± 0.166. The LD declined considerably at distances greater than 15 and 20 kb, with values lower than 0.3 and 0.2, respectively. The current Ne was 99 animals. There was a marked reduction in this parameter when the estimated Ne of 16 generations ago was considered, which was 650 animals. These results may be linked to a broad and partially open genetic base and to increasing selection pressures in the breed. Finally, we observed defined population substructures that were more related to the breed's important sires rather than to the type of gait. |
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Genomic analysis of the population structure in horses of the Brazilian Mangalarga Marchador breedEffective sizeLinkage disequilibriumPopulation structureSNPThe Mangalarga Marchador is the Brazilian saddle horse. It has two characteristic gaits, marcha batida and marcha picada, that provide greater comfort to the rider during cavalcade and work. This horse breed is mainly used for work on beef cattle farms and different modalities of equestrian sports. The objective of this study was to characterize the linkage disequilibrium (LD), calculated by r², of Brazilian Mangalarga Marchador horses raised in Brazil using large-scale SNP genotyping. We also investigated the effective size (Ne) of the population, as well as its structure and relationships. A total of 240 Mangalarga Marchador horses of both sexes, registered with the Brazilian breeders association (ABCCMM), were used. The number of informative SNPs was 377,308. Principal component analysis showed that Mangalarga Marchador horses of the two different gait types belong to the same population, i.e., these groups did not segregate significantly within the breed. This finding should be taken into consideration in genetic population studies. The estimated genomic r² was 0.096 ± 0.166. The LD declined considerably at distances greater than 15 and 20 kb, with values lower than 0.3 and 0.2, respectively. The current Ne was 99 animals. There was a marked reduction in this parameter when the estimated Ne of 16 generations ago was considered, which was 650 animals. These results may be linked to a broad and partially open genetic base and to increasing selection pressures in the breed. Finally, we observed defined population substructures that were more related to the breed's important sires rather than to the type of gait.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Department of Animal Science College of Agriculture and Veterinary Science São Paulo State University (FCAV/UNESP)Department of Animal Breeding and Nutrition College of Veterinary and Animal Science São Paulo State University (FMVZ/UNESP)Department of Animal Science College of Animal Science and Food Engineering University of São Paulo (FZEA/USP)Department of Animal Nutrition and Production College of Veterinary Medicine and Animal Science University of São Paulo (FMVZ/USP)Department of Animal Science College of Agriculture and Veterinary Science São Paulo State University (FCAV/UNESP)Department of Animal Breeding and Nutrition College of Veterinary and Animal Science São Paulo State University (FMVZ/UNESP)CAPES: 001FAPESP: 2016/19081-9Universidade Estadual Paulista (Unesp)Universidade de São Paulo (USP)dos Santos, Bruna A. [UNESP]Pereira, Guilherme L. [UNESP]Bussiman, Fernando de O.Paschoal, Victória R. [UNESP]de Souza Júnior, Sérgio M. [UNESP]Balieiro, Júlio César de C.Chardulo, Luís Artur L. [UNESP]Curi, Rogério A. [UNESP]2019-10-06T16:47:52Z2019-10-06T16:47:52Z2019-11-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article49-55http://dx.doi.org/10.1016/j.livsci.2019.09.010Livestock Science, v. 229, p. 49-55.1871-1413http://hdl.handle.net/11449/18966010.1016/j.livsci.2019.09.0102-s2.0-8507226413035147134139191260000-0001-6289-0406Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengLivestock Scienceinfo:eu-repo/semantics/openAccess2024-09-06T18:54:42Zoai:repositorio.unesp.br:11449/189660Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-06T18:54:42Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Genomic analysis of the population structure in horses of the Brazilian Mangalarga Marchador breed |
title |
Genomic analysis of the population structure in horses of the Brazilian Mangalarga Marchador breed |
spellingShingle |
Genomic analysis of the population structure in horses of the Brazilian Mangalarga Marchador breed dos Santos, Bruna A. [UNESP] Effective size Linkage disequilibrium Population structure SNP |
title_short |
Genomic analysis of the population structure in horses of the Brazilian Mangalarga Marchador breed |
title_full |
Genomic analysis of the population structure in horses of the Brazilian Mangalarga Marchador breed |
title_fullStr |
Genomic analysis of the population structure in horses of the Brazilian Mangalarga Marchador breed |
title_full_unstemmed |
Genomic analysis of the population structure in horses of the Brazilian Mangalarga Marchador breed |
title_sort |
Genomic analysis of the population structure in horses of the Brazilian Mangalarga Marchador breed |
author |
dos Santos, Bruna A. [UNESP] |
author_facet |
dos Santos, Bruna A. [UNESP] Pereira, Guilherme L. [UNESP] Bussiman, Fernando de O. Paschoal, Victória R. [UNESP] de Souza Júnior, Sérgio M. [UNESP] Balieiro, Júlio César de C. Chardulo, Luís Artur L. [UNESP] Curi, Rogério A. [UNESP] |
author_role |
author |
author2 |
Pereira, Guilherme L. [UNESP] Bussiman, Fernando de O. Paschoal, Victória R. [UNESP] de Souza Júnior, Sérgio M. [UNESP] Balieiro, Júlio César de C. Chardulo, Luís Artur L. [UNESP] Curi, Rogério A. [UNESP] |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Universidade de São Paulo (USP) |
dc.contributor.author.fl_str_mv |
dos Santos, Bruna A. [UNESP] Pereira, Guilherme L. [UNESP] Bussiman, Fernando de O. Paschoal, Victória R. [UNESP] de Souza Júnior, Sérgio M. [UNESP] Balieiro, Júlio César de C. Chardulo, Luís Artur L. [UNESP] Curi, Rogério A. [UNESP] |
dc.subject.por.fl_str_mv |
Effective size Linkage disequilibrium Population structure SNP |
topic |
Effective size Linkage disequilibrium Population structure SNP |
description |
The Mangalarga Marchador is the Brazilian saddle horse. It has two characteristic gaits, marcha batida and marcha picada, that provide greater comfort to the rider during cavalcade and work. This horse breed is mainly used for work on beef cattle farms and different modalities of equestrian sports. The objective of this study was to characterize the linkage disequilibrium (LD), calculated by r², of Brazilian Mangalarga Marchador horses raised in Brazil using large-scale SNP genotyping. We also investigated the effective size (Ne) of the population, as well as its structure and relationships. A total of 240 Mangalarga Marchador horses of both sexes, registered with the Brazilian breeders association (ABCCMM), were used. The number of informative SNPs was 377,308. Principal component analysis showed that Mangalarga Marchador horses of the two different gait types belong to the same population, i.e., these groups did not segregate significantly within the breed. This finding should be taken into consideration in genetic population studies. The estimated genomic r² was 0.096 ± 0.166. The LD declined considerably at distances greater than 15 and 20 kb, with values lower than 0.3 and 0.2, respectively. The current Ne was 99 animals. There was a marked reduction in this parameter when the estimated Ne of 16 generations ago was considered, which was 650 animals. These results may be linked to a broad and partially open genetic base and to increasing selection pressures in the breed. Finally, we observed defined population substructures that were more related to the breed's important sires rather than to the type of gait. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-10-06T16:47:52Z 2019-10-06T16:47:52Z 2019-11-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.livsci.2019.09.010 Livestock Science, v. 229, p. 49-55. 1871-1413 http://hdl.handle.net/11449/189660 10.1016/j.livsci.2019.09.010 2-s2.0-85072264130 3514713413919126 0000-0001-6289-0406 |
url |
http://dx.doi.org/10.1016/j.livsci.2019.09.010 http://hdl.handle.net/11449/189660 |
identifier_str_mv |
Livestock Science, v. 229, p. 49-55. 1871-1413 10.1016/j.livsci.2019.09.010 2-s2.0-85072264130 3514713413919126 0000-0001-6289-0406 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Livestock Science |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
49-55 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
repositoriounesp@unesp.br |
_version_ |
1810021316152000512 |