Cytomorphological and immunocytochemical evaluation of fine needle aspirates from high grade non-Hodgkin's lymphomas.
Autor(a) principal: | |
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Data de Publicação: | 1992 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://hdl.handle.net/11449/223944 |
Resumo: | 1. Fine needle aspirates from ten patients with high-grade malignant non-Hodgkin's lymphomas were analyzed by cytomorphology and immunocytochemistry. 2. The following morphologic diagnoses were made: lymphoblastic lymphoma (3 cases), Burkitt's lymphoma (3 cases), mixed small and large cell lymphomas with predominance of large cells (2 cases), and centroblastic lymphoma (2 cases). Immunocytochemistry showed a B-cell phenotype in five cases and a T-cell phenotype in four. One case of lymphoblastic lymphoma was negative for the T and B cell markers used. 3. The results of histological and immunohistochemical analyses performed on surgical biopsies from 8 patients confirmed the morphological diagnosis in all cases. Two cases of Burkitt's lymphoma were submitted only to cytological and immunological diagnosis. 4. The high diagnostic accuracy of combined cytomorphology and immunocytochemical assessment of fine needle aspirate samples validates the use of the technique in the diagnostic work-up of high-grade non-Hodgkin's lymphomas. |
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Cytomorphological and immunocytochemical evaluation of fine needle aspirates from high grade non-Hodgkin's lymphomas.1. Fine needle aspirates from ten patients with high-grade malignant non-Hodgkin's lymphomas were analyzed by cytomorphology and immunocytochemistry. 2. The following morphologic diagnoses were made: lymphoblastic lymphoma (3 cases), Burkitt's lymphoma (3 cases), mixed small and large cell lymphomas with predominance of large cells (2 cases), and centroblastic lymphoma (2 cases). Immunocytochemistry showed a B-cell phenotype in five cases and a T-cell phenotype in four. One case of lymphoblastic lymphoma was negative for the T and B cell markers used. 3. The results of histological and immunohistochemical analyses performed on surgical biopsies from 8 patients confirmed the morphological diagnosis in all cases. Two cases of Burkitt's lymphoma were submitted only to cytological and immunological diagnosis. 4. The high diagnostic accuracy of combined cytomorphology and immunocytochemical assessment of fine needle aspirate samples validates the use of the technique in the diagnostic work-up of high-grade non-Hodgkin's lymphomas.Departamento de Patologia Faculdade de Medicina de Botucatu Universidade Estadual Paulista SPDepartamento de Patologia Faculdade de Medicina de Botucatu Universidade Estadual Paulista SPUniversidade Estadual Paulista (UNESP)Schmitt, F. C. [UNESP]Maeda, S. A. [UNESP]Hokama, N. K. [UNESP]Machado, P. E. [UNESP]Niero-Melo, L. [UNESP]2022-04-28T19:53:54Z2022-04-28T19:53:54Z1992-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article691-696Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.], v. 25, n. 7, p. 691-696, 1992.0100-879Xhttp://hdl.handle.net/11449/2239442-s2.0-0026956330Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBrazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.]info:eu-repo/semantics/openAccess2024-09-03T13:15:04Zoai:repositorio.unesp.br:11449/223944Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-03T13:15:04Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Cytomorphological and immunocytochemical evaluation of fine needle aspirates from high grade non-Hodgkin's lymphomas. |
title |
Cytomorphological and immunocytochemical evaluation of fine needle aspirates from high grade non-Hodgkin's lymphomas. |
spellingShingle |
Cytomorphological and immunocytochemical evaluation of fine needle aspirates from high grade non-Hodgkin's lymphomas. Schmitt, F. C. [UNESP] |
title_short |
Cytomorphological and immunocytochemical evaluation of fine needle aspirates from high grade non-Hodgkin's lymphomas. |
title_full |
Cytomorphological and immunocytochemical evaluation of fine needle aspirates from high grade non-Hodgkin's lymphomas. |
title_fullStr |
Cytomorphological and immunocytochemical evaluation of fine needle aspirates from high grade non-Hodgkin's lymphomas. |
title_full_unstemmed |
Cytomorphological and immunocytochemical evaluation of fine needle aspirates from high grade non-Hodgkin's lymphomas. |
title_sort |
Cytomorphological and immunocytochemical evaluation of fine needle aspirates from high grade non-Hodgkin's lymphomas. |
author |
Schmitt, F. C. [UNESP] |
author_facet |
Schmitt, F. C. [UNESP] Maeda, S. A. [UNESP] Hokama, N. K. [UNESP] Machado, P. E. [UNESP] Niero-Melo, L. [UNESP] |
author_role |
author |
author2 |
Maeda, S. A. [UNESP] Hokama, N. K. [UNESP] Machado, P. E. [UNESP] Niero-Melo, L. [UNESP] |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Schmitt, F. C. [UNESP] Maeda, S. A. [UNESP] Hokama, N. K. [UNESP] Machado, P. E. [UNESP] Niero-Melo, L. [UNESP] |
description |
1. Fine needle aspirates from ten patients with high-grade malignant non-Hodgkin's lymphomas were analyzed by cytomorphology and immunocytochemistry. 2. The following morphologic diagnoses were made: lymphoblastic lymphoma (3 cases), Burkitt's lymphoma (3 cases), mixed small and large cell lymphomas with predominance of large cells (2 cases), and centroblastic lymphoma (2 cases). Immunocytochemistry showed a B-cell phenotype in five cases and a T-cell phenotype in four. One case of lymphoblastic lymphoma was negative for the T and B cell markers used. 3. The results of histological and immunohistochemical analyses performed on surgical biopsies from 8 patients confirmed the morphological diagnosis in all cases. Two cases of Burkitt's lymphoma were submitted only to cytological and immunological diagnosis. 4. The high diagnostic accuracy of combined cytomorphology and immunocytochemical assessment of fine needle aspirate samples validates the use of the technique in the diagnostic work-up of high-grade non-Hodgkin's lymphomas. |
publishDate |
1992 |
dc.date.none.fl_str_mv |
1992-01-01 2022-04-28T19:53:54Z 2022-04-28T19:53:54Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.], v. 25, n. 7, p. 691-696, 1992. 0100-879X http://hdl.handle.net/11449/223944 2-s2.0-0026956330 |
identifier_str_mv |
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.], v. 25, n. 7, p. 691-696, 1992. 0100-879X 2-s2.0-0026956330 |
url |
http://hdl.handle.net/11449/223944 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
691-696 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
repositoriounesp@unesp.br |
_version_ |
1810021379587702784 |