Brown recluse spider venom: Proteomic analysis and proposal of a putative mechanism of action
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.2174/092986609788923383 http://hdl.handle.net/11449/225584 |
Resumo: | Loxosceles intermedia spider venom was subjected to proteomic analysis through a MudPIT shot-gun approach to identify the protein composition. Were identified 39 proteins which seem to responsible by the lesion of different types of tissues, to some physiopathological actions and by the prevention of structural damage to the toxin structures. © 2009 Bentham Science Publishers Ltd. |
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Brown recluse spider venom: Proteomic analysis and proposal of a putative mechanism of actionMass spectrometryMechanism of actionMudPITProteomic analysisSpider venomLoxosceles intermedia spider venom was subjected to proteomic analysis through a MudPIT shot-gun approach to identify the protein composition. Were identified 39 proteins which seem to responsible by the lesion of different types of tissues, to some physiopathological actions and by the prevention of structural damage to the toxin structures. © 2009 Bentham Science Publishers Ltd.Laboratory of Structural Biology and Zoochemistry CEIS/Dept. Biology Institute of Biosciences of Rio Claro, Rio Claro, SPLab. Structural Biology CEIS IBRC-UNESP, Avenue 24A 1515, Bela Vista, Rio Claro, SP CEP 13506-900Lab. Structural Biology CEIS IBRC-UNESP, Avenue 24A 1515, Bela Vista, Rio Claro, SP CEP 13506-900Institute of Biosciences of Rio ClaroUniversidade Estadual Paulista (UNESP)Dos Santos, Lucilene D.Dias, Nathalia B.Pinto, José Robert O.A.S.Palma, Mario S. [UNESP]2022-04-28T20:54:50Z2022-04-28T20:54:50Z2009-08-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article933-943http://dx.doi.org/10.2174/092986609788923383Protein and Peptide Letters, v. 16, n. 8, p. 933-943, 2009.0929-8665http://hdl.handle.net/11449/22558410.2174/0929866097889233832-s2.0-68849083284Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengProtein and Peptide Lettersinfo:eu-repo/semantics/openAccess2022-04-28T20:54:50Zoai:repositorio.unesp.br:11449/225584Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T17:18:32.284918Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Brown recluse spider venom: Proteomic analysis and proposal of a putative mechanism of action |
title |
Brown recluse spider venom: Proteomic analysis and proposal of a putative mechanism of action |
spellingShingle |
Brown recluse spider venom: Proteomic analysis and proposal of a putative mechanism of action Dos Santos, Lucilene D. Mass spectrometry Mechanism of action MudPIT Proteomic analysis Spider venom |
title_short |
Brown recluse spider venom: Proteomic analysis and proposal of a putative mechanism of action |
title_full |
Brown recluse spider venom: Proteomic analysis and proposal of a putative mechanism of action |
title_fullStr |
Brown recluse spider venom: Proteomic analysis and proposal of a putative mechanism of action |
title_full_unstemmed |
Brown recluse spider venom: Proteomic analysis and proposal of a putative mechanism of action |
title_sort |
Brown recluse spider venom: Proteomic analysis and proposal of a putative mechanism of action |
author |
Dos Santos, Lucilene D. |
author_facet |
Dos Santos, Lucilene D. Dias, Nathalia B. Pinto, José Robert O.A.S. Palma, Mario S. [UNESP] |
author_role |
author |
author2 |
Dias, Nathalia B. Pinto, José Robert O.A.S. Palma, Mario S. [UNESP] |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Institute of Biosciences of Rio Claro Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Dos Santos, Lucilene D. Dias, Nathalia B. Pinto, José Robert O.A.S. Palma, Mario S. [UNESP] |
dc.subject.por.fl_str_mv |
Mass spectrometry Mechanism of action MudPIT Proteomic analysis Spider venom |
topic |
Mass spectrometry Mechanism of action MudPIT Proteomic analysis Spider venom |
description |
Loxosceles intermedia spider venom was subjected to proteomic analysis through a MudPIT shot-gun approach to identify the protein composition. Were identified 39 proteins which seem to responsible by the lesion of different types of tissues, to some physiopathological actions and by the prevention of structural damage to the toxin structures. © 2009 Bentham Science Publishers Ltd. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-08-01 2022-04-28T20:54:50Z 2022-04-28T20:54:50Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.2174/092986609788923383 Protein and Peptide Letters, v. 16, n. 8, p. 933-943, 2009. 0929-8665 http://hdl.handle.net/11449/225584 10.2174/092986609788923383 2-s2.0-68849083284 |
url |
http://dx.doi.org/10.2174/092986609788923383 http://hdl.handle.net/11449/225584 |
identifier_str_mv |
Protein and Peptide Letters, v. 16, n. 8, p. 933-943, 2009. 0929-8665 10.2174/092986609788923383 2-s2.0-68849083284 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Protein and Peptide Letters |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
933-943 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128789450850304 |