Low appendicular muscle mass is correlated with femoral neck bone mineral density loss in postmenopausal women

Detalhes bibliográficos
Autor(a) principal: Orsatti, Fabio L.
Data de Publicação: 2011
Outros Autores: Nahás, Eliana Aguiar Petri [UNESP], Nahas-Neto, Jorge [UNESP], Orsatti, Claudio L. [UNESP], Marocolo, Moacir, Barbosa-Neto, Octavio, da Mota, Gustavo R.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1186/1471-2474-12-225
http://hdl.handle.net/11449/12266
Resumo: Background: After menopause, rapid bone mass loss occurs in response to hypoestrogenism. Several studies suggest that muscle mass and bone mineral density (BMD) are positively associated in postmenopausal women. Therefore, it may be assumed that postmenopausal low appendicular muscle mass (aMM) can increase BMD loss in a short period of time.Objective: The purpose of this study was to assess relationship of aMM with femoral neck BMD in postmenopausal women.Methods: Prospective, controlled clinical Trial including 64 women aged 45-70 years, who had not had their last menstruation for at least one year. Subjects were divided into two groups: low aMM (n = 32), and normal aMM (n-32). Femoral neck BMD and muscle mass were measured by DXA at baseline and after twelve months. Pairwise and independent t tests were used for data analysis.Results: Baseline weight, BMI and muscle mass (total and appendicular) significantly differ between groups (p < 0.05). After twelve months, femoral neck BMD was significantly lower in the group with low aMM, whereas no significant difference was observed in the group with normal aMM (p < 0.05).Conclusion: In postmenopausal women, low appendicular muscle mass is associated negatively with femoral neck BMD in a short period of time.
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spelling Low appendicular muscle mass is correlated with femoral neck bone mineral density loss in postmenopausal womensarcopeniaosteoporosismenopausebody compositionDXABackground: After menopause, rapid bone mass loss occurs in response to hypoestrogenism. Several studies suggest that muscle mass and bone mineral density (BMD) are positively associated in postmenopausal women. Therefore, it may be assumed that postmenopausal low appendicular muscle mass (aMM) can increase BMD loss in a short period of time.Objective: The purpose of this study was to assess relationship of aMM with femoral neck BMD in postmenopausal women.Methods: Prospective, controlled clinical Trial including 64 women aged 45-70 years, who had not had their last menstruation for at least one year. Subjects were divided into two groups: low aMM (n = 32), and normal aMM (n-32). Femoral neck BMD and muscle mass were measured by DXA at baseline and after twelve months. Pairwise and independent t tests were used for data analysis.Results: Baseline weight, BMI and muscle mass (total and appendicular) significantly differ between groups (p < 0.05). After twelve months, femoral neck BMD was significantly lower in the group with low aMM, whereas no significant difference was observed in the group with normal aMM (p < 0.05).Conclusion: In postmenopausal women, low appendicular muscle mass is associated negatively with femoral neck BMD in a short period of time.Fundação Lucentis de Apoio a Cultura, Ensino, Pesquisa e ExtensaoConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Triangulo Mineiro Fed Univ UFTM, Hlth Sci Inst, Exercise Biol Lab BioEx, Uberaba, MG, BrazilSão Paulo State Univ UNESP, Botucatu Med Sch, Dept Gynecol & Obstet, São Paulo, BrazilSão Paulo State Univ UNESP, Botucatu Med Sch, Postgrad Program Gynecol Obstet & Mastol, São Paulo, BrazilSão Paulo State Univ UNESP, Botucatu Med Sch, Dept Gynecol & Obstet, São Paulo, BrazilSão Paulo State Univ UNESP, Botucatu Med Sch, Postgrad Program Gynecol Obstet & Mastol, São Paulo, BrazilBiomed Central Ltd.Universidade Federal do Triângulo Mineiro (UFTM)Universidade Estadual Paulista (Unesp)Orsatti, Fabio L.Nahás, Eliana Aguiar Petri [UNESP]Nahas-Neto, Jorge [UNESP]Orsatti, Claudio L. [UNESP]Marocolo, MoacirBarbosa-Neto, Octavioda Mota, Gustavo R.2014-05-20T13:35:37Z2014-05-20T13:35:37Z2011-10-07info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article6application/pdfhttp://dx.doi.org/10.1186/1471-2474-12-225Bmc Musculoskeletal Disorders. London: Biomed Central Ltd., v. 12, p. 6, 2011.1471-2474http://hdl.handle.net/11449/1226610.1186/1471-2474-12-225WOS:000297480200001WOS000297480200001.pdf4155170574788417Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBmc Musculoskeletal Disorders1.9980,951info:eu-repo/semantics/openAccess2024-08-16T14:07:07Zoai:repositorio.unesp.br:11449/12266Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-16T14:07:07Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Low appendicular muscle mass is correlated with femoral neck bone mineral density loss in postmenopausal women
title Low appendicular muscle mass is correlated with femoral neck bone mineral density loss in postmenopausal women
spellingShingle Low appendicular muscle mass is correlated with femoral neck bone mineral density loss in postmenopausal women
Orsatti, Fabio L.
sarcopenia
osteoporosis
menopause
body composition
DXA
title_short Low appendicular muscle mass is correlated with femoral neck bone mineral density loss in postmenopausal women
title_full Low appendicular muscle mass is correlated with femoral neck bone mineral density loss in postmenopausal women
title_fullStr Low appendicular muscle mass is correlated with femoral neck bone mineral density loss in postmenopausal women
title_full_unstemmed Low appendicular muscle mass is correlated with femoral neck bone mineral density loss in postmenopausal women
title_sort Low appendicular muscle mass is correlated with femoral neck bone mineral density loss in postmenopausal women
author Orsatti, Fabio L.
author_facet Orsatti, Fabio L.
Nahás, Eliana Aguiar Petri [UNESP]
Nahas-Neto, Jorge [UNESP]
Orsatti, Claudio L. [UNESP]
Marocolo, Moacir
Barbosa-Neto, Octavio
da Mota, Gustavo R.
author_role author
author2 Nahás, Eliana Aguiar Petri [UNESP]
Nahas-Neto, Jorge [UNESP]
Orsatti, Claudio L. [UNESP]
Marocolo, Moacir
Barbosa-Neto, Octavio
da Mota, Gustavo R.
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal do Triângulo Mineiro (UFTM)
Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Orsatti, Fabio L.
Nahás, Eliana Aguiar Petri [UNESP]
Nahas-Neto, Jorge [UNESP]
Orsatti, Claudio L. [UNESP]
Marocolo, Moacir
Barbosa-Neto, Octavio
da Mota, Gustavo R.
dc.subject.por.fl_str_mv sarcopenia
osteoporosis
menopause
body composition
DXA
topic sarcopenia
osteoporosis
menopause
body composition
DXA
description Background: After menopause, rapid bone mass loss occurs in response to hypoestrogenism. Several studies suggest that muscle mass and bone mineral density (BMD) are positively associated in postmenopausal women. Therefore, it may be assumed that postmenopausal low appendicular muscle mass (aMM) can increase BMD loss in a short period of time.Objective: The purpose of this study was to assess relationship of aMM with femoral neck BMD in postmenopausal women.Methods: Prospective, controlled clinical Trial including 64 women aged 45-70 years, who had not had their last menstruation for at least one year. Subjects were divided into two groups: low aMM (n = 32), and normal aMM (n-32). Femoral neck BMD and muscle mass were measured by DXA at baseline and after twelve months. Pairwise and independent t tests were used for data analysis.Results: Baseline weight, BMI and muscle mass (total and appendicular) significantly differ between groups (p < 0.05). After twelve months, femoral neck BMD was significantly lower in the group with low aMM, whereas no significant difference was observed in the group with normal aMM (p < 0.05).Conclusion: In postmenopausal women, low appendicular muscle mass is associated negatively with femoral neck BMD in a short period of time.
publishDate 2011
dc.date.none.fl_str_mv 2011-10-07
2014-05-20T13:35:37Z
2014-05-20T13:35:37Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1186/1471-2474-12-225
Bmc Musculoskeletal Disorders. London: Biomed Central Ltd., v. 12, p. 6, 2011.
1471-2474
http://hdl.handle.net/11449/12266
10.1186/1471-2474-12-225
WOS:000297480200001
WOS000297480200001.pdf
4155170574788417
url http://dx.doi.org/10.1186/1471-2474-12-225
http://hdl.handle.net/11449/12266
identifier_str_mv Bmc Musculoskeletal Disorders. London: Biomed Central Ltd., v. 12, p. 6, 2011.
1471-2474
10.1186/1471-2474-12-225
WOS:000297480200001
WOS000297480200001.pdf
4155170574788417
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Bmc Musculoskeletal Disorders
1.998
0,951
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 6
application/pdf
dc.publisher.none.fl_str_mv Biomed Central Ltd.
publisher.none.fl_str_mv Biomed Central Ltd.
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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