Low appendicular muscle mass is correlated with femoral neck bone mineral density loss in postmenopausal women
Autor(a) principal: | |
---|---|
Data de Publicação: | 2011 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1186/1471-2474-12-225 http://hdl.handle.net/11449/12266 |
Resumo: | Background: After menopause, rapid bone mass loss occurs in response to hypoestrogenism. Several studies suggest that muscle mass and bone mineral density (BMD) are positively associated in postmenopausal women. Therefore, it may be assumed that postmenopausal low appendicular muscle mass (aMM) can increase BMD loss in a short period of time.Objective: The purpose of this study was to assess relationship of aMM with femoral neck BMD in postmenopausal women.Methods: Prospective, controlled clinical Trial including 64 women aged 45-70 years, who had not had their last menstruation for at least one year. Subjects were divided into two groups: low aMM (n = 32), and normal aMM (n-32). Femoral neck BMD and muscle mass were measured by DXA at baseline and after twelve months. Pairwise and independent t tests were used for data analysis.Results: Baseline weight, BMI and muscle mass (total and appendicular) significantly differ between groups (p < 0.05). After twelve months, femoral neck BMD was significantly lower in the group with low aMM, whereas no significant difference was observed in the group with normal aMM (p < 0.05).Conclusion: In postmenopausal women, low appendicular muscle mass is associated negatively with femoral neck BMD in a short period of time. |
id |
UNSP_84b465c0b7f8e68cc021a6af4a87d303 |
---|---|
oai_identifier_str |
oai:repositorio.unesp.br:11449/12266 |
network_acronym_str |
UNSP |
network_name_str |
Repositório Institucional da UNESP |
repository_id_str |
2946 |
spelling |
Low appendicular muscle mass is correlated with femoral neck bone mineral density loss in postmenopausal womensarcopeniaosteoporosismenopausebody compositionDXABackground: After menopause, rapid bone mass loss occurs in response to hypoestrogenism. Several studies suggest that muscle mass and bone mineral density (BMD) are positively associated in postmenopausal women. Therefore, it may be assumed that postmenopausal low appendicular muscle mass (aMM) can increase BMD loss in a short period of time.Objective: The purpose of this study was to assess relationship of aMM with femoral neck BMD in postmenopausal women.Methods: Prospective, controlled clinical Trial including 64 women aged 45-70 years, who had not had their last menstruation for at least one year. Subjects were divided into two groups: low aMM (n = 32), and normal aMM (n-32). Femoral neck BMD and muscle mass were measured by DXA at baseline and after twelve months. Pairwise and independent t tests were used for data analysis.Results: Baseline weight, BMI and muscle mass (total and appendicular) significantly differ between groups (p < 0.05). After twelve months, femoral neck BMD was significantly lower in the group with low aMM, whereas no significant difference was observed in the group with normal aMM (p < 0.05).Conclusion: In postmenopausal women, low appendicular muscle mass is associated negatively with femoral neck BMD in a short period of time.Fundação Lucentis de Apoio a Cultura, Ensino, Pesquisa e ExtensaoConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Triangulo Mineiro Fed Univ UFTM, Hlth Sci Inst, Exercise Biol Lab BioEx, Uberaba, MG, BrazilSão Paulo State Univ UNESP, Botucatu Med Sch, Dept Gynecol & Obstet, São Paulo, BrazilSão Paulo State Univ UNESP, Botucatu Med Sch, Postgrad Program Gynecol Obstet & Mastol, São Paulo, BrazilSão Paulo State Univ UNESP, Botucatu Med Sch, Dept Gynecol & Obstet, São Paulo, BrazilSão Paulo State Univ UNESP, Botucatu Med Sch, Postgrad Program Gynecol Obstet & Mastol, São Paulo, BrazilBiomed Central Ltd.Universidade Federal do Triângulo Mineiro (UFTM)Universidade Estadual Paulista (Unesp)Orsatti, Fabio L.Nahás, Eliana Aguiar Petri [UNESP]Nahas-Neto, Jorge [UNESP]Orsatti, Claudio L. [UNESP]Marocolo, MoacirBarbosa-Neto, Octavioda Mota, Gustavo R.2014-05-20T13:35:37Z2014-05-20T13:35:37Z2011-10-07info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article6application/pdfhttp://dx.doi.org/10.1186/1471-2474-12-225Bmc Musculoskeletal Disorders. London: Biomed Central Ltd., v. 12, p. 6, 2011.1471-2474http://hdl.handle.net/11449/1226610.1186/1471-2474-12-225WOS:000297480200001WOS000297480200001.pdf4155170574788417Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBmc Musculoskeletal Disorders1.9980,951info:eu-repo/semantics/openAccess2024-08-16T14:07:07Zoai:repositorio.unesp.br:11449/12266Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-16T14:07:07Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Low appendicular muscle mass is correlated with femoral neck bone mineral density loss in postmenopausal women |
title |
Low appendicular muscle mass is correlated with femoral neck bone mineral density loss in postmenopausal women |
spellingShingle |
Low appendicular muscle mass is correlated with femoral neck bone mineral density loss in postmenopausal women Orsatti, Fabio L. sarcopenia osteoporosis menopause body composition DXA |
title_short |
Low appendicular muscle mass is correlated with femoral neck bone mineral density loss in postmenopausal women |
title_full |
Low appendicular muscle mass is correlated with femoral neck bone mineral density loss in postmenopausal women |
title_fullStr |
Low appendicular muscle mass is correlated with femoral neck bone mineral density loss in postmenopausal women |
title_full_unstemmed |
Low appendicular muscle mass is correlated with femoral neck bone mineral density loss in postmenopausal women |
title_sort |
Low appendicular muscle mass is correlated with femoral neck bone mineral density loss in postmenopausal women |
author |
Orsatti, Fabio L. |
author_facet |
Orsatti, Fabio L. Nahás, Eliana Aguiar Petri [UNESP] Nahas-Neto, Jorge [UNESP] Orsatti, Claudio L. [UNESP] Marocolo, Moacir Barbosa-Neto, Octavio da Mota, Gustavo R. |
author_role |
author |
author2 |
Nahás, Eliana Aguiar Petri [UNESP] Nahas-Neto, Jorge [UNESP] Orsatti, Claudio L. [UNESP] Marocolo, Moacir Barbosa-Neto, Octavio da Mota, Gustavo R. |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Federal do Triângulo Mineiro (UFTM) Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Orsatti, Fabio L. Nahás, Eliana Aguiar Petri [UNESP] Nahas-Neto, Jorge [UNESP] Orsatti, Claudio L. [UNESP] Marocolo, Moacir Barbosa-Neto, Octavio da Mota, Gustavo R. |
dc.subject.por.fl_str_mv |
sarcopenia osteoporosis menopause body composition DXA |
topic |
sarcopenia osteoporosis menopause body composition DXA |
description |
Background: After menopause, rapid bone mass loss occurs in response to hypoestrogenism. Several studies suggest that muscle mass and bone mineral density (BMD) are positively associated in postmenopausal women. Therefore, it may be assumed that postmenopausal low appendicular muscle mass (aMM) can increase BMD loss in a short period of time.Objective: The purpose of this study was to assess relationship of aMM with femoral neck BMD in postmenopausal women.Methods: Prospective, controlled clinical Trial including 64 women aged 45-70 years, who had not had their last menstruation for at least one year. Subjects were divided into two groups: low aMM (n = 32), and normal aMM (n-32). Femoral neck BMD and muscle mass were measured by DXA at baseline and after twelve months. Pairwise and independent t tests were used for data analysis.Results: Baseline weight, BMI and muscle mass (total and appendicular) significantly differ between groups (p < 0.05). After twelve months, femoral neck BMD was significantly lower in the group with low aMM, whereas no significant difference was observed in the group with normal aMM (p < 0.05).Conclusion: In postmenopausal women, low appendicular muscle mass is associated negatively with femoral neck BMD in a short period of time. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-10-07 2014-05-20T13:35:37Z 2014-05-20T13:35:37Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1186/1471-2474-12-225 Bmc Musculoskeletal Disorders. London: Biomed Central Ltd., v. 12, p. 6, 2011. 1471-2474 http://hdl.handle.net/11449/12266 10.1186/1471-2474-12-225 WOS:000297480200001 WOS000297480200001.pdf 4155170574788417 |
url |
http://dx.doi.org/10.1186/1471-2474-12-225 http://hdl.handle.net/11449/12266 |
identifier_str_mv |
Bmc Musculoskeletal Disorders. London: Biomed Central Ltd., v. 12, p. 6, 2011. 1471-2474 10.1186/1471-2474-12-225 WOS:000297480200001 WOS000297480200001.pdf 4155170574788417 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Bmc Musculoskeletal Disorders 1.998 0,951 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
6 application/pdf |
dc.publisher.none.fl_str_mv |
Biomed Central Ltd. |
publisher.none.fl_str_mv |
Biomed Central Ltd. |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128146299420672 |