Risk stratification and geographical mapping of Brazilian inflammatory bowel disease patients during the COVID-19 outbreak: Results from a nationwide survey

Detalhes bibliográficos
Autor(a) principal: Queiroz, Natália Sousa Freitas
Data de Publicação: 2021
Outros Autores: Teixeira, Fábio Vieira, Motta, Marina Pamponet, Chebli, Liliana Andrade, Hino, Adriano Akira Ferreira, de Almeida Martins, Camilla, Quaresma, Abel Botelho, de Paula da Silva, Alexandre Augusto, Damião, Adérson Omar Mourão Cintra, Saad-Hossne, Rogerio [UNESP], Kotze, Paulo Gustavo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.3748/wjg.v27.i12.1226
http://hdl.handle.net/11449/208569
Resumo: BACKGROUND Coronavirus disease 2019 (COVID-19) pandemic is still evolving globally, and Brazil is currently one of the most affected countries. It is still debated whether patients with inflammatory bowel disease (IBD) are at a higher risk for developing COVID-19 or its complications. AIM To assess geographical distribution of IBD patients at the highest risk and correlate these data with COVID-19 mortality rates in Brazil. METHODS The Brazilian IBD Study Group (Grupo de Estudos da Doença Inflamatória Intestinal do Brasil) developed a web-based survey adapted from the British Society of Gastroenterology guidelines. The included categories were demographic data and inquiries related to risk factors for complications from COVID-19. Patients were categorized as highest, moderate or lowest individual risk. The Spearman correlation test was used to identify any association between highest risk and mortality rates for each state of the country. RESULTS A total of 3568 patients (65.3% females) were included. Most participants were from the southeastern and southern regions of Brazil, and 84.1% were using immunomodulators and/or biologics. Most patients (55.1%) were at moderate risk, 23.4% were at highest risk and 21.5% were at lowest risk of COVID-19 complications. No association between the proportion of IBD patients at highest risk for COVID-19 complications and higher mortality rates was identified in different Brazilian states (r = 0.146, P = 0.467). CONCLUSION This study indicates a distinct geographical distribution of IBD patients at highest risk for COVID-19 complications in different states of the country, which may reflect contrasting socioeconomic, educational and healthcare aspects. No association between high risk of IBD and COVID-related mortality rates was identified.
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spelling Risk stratification and geographical mapping of Brazilian inflammatory bowel disease patients during the COVID-19 outbreak: Results from a nationwide surveyBrazilColitisCOVID-19Crohn's diseaseInflammatory bowel diseaseUlcerativeBACKGROUND Coronavirus disease 2019 (COVID-19) pandemic is still evolving globally, and Brazil is currently one of the most affected countries. It is still debated whether patients with inflammatory bowel disease (IBD) are at a higher risk for developing COVID-19 or its complications. AIM To assess geographical distribution of IBD patients at the highest risk and correlate these data with COVID-19 mortality rates in Brazil. METHODS The Brazilian IBD Study Group (Grupo de Estudos da Doença Inflamatória Intestinal do Brasil) developed a web-based survey adapted from the British Society of Gastroenterology guidelines. The included categories were demographic data and inquiries related to risk factors for complications from COVID-19. Patients were categorized as highest, moderate or lowest individual risk. The Spearman correlation test was used to identify any association between highest risk and mortality rates for each state of the country. RESULTS A total of 3568 patients (65.3% females) were included. Most participants were from the southeastern and southern regions of Brazil, and 84.1% were using immunomodulators and/or biologics. Most patients (55.1%) were at moderate risk, 23.4% were at highest risk and 21.5% were at lowest risk of COVID-19 complications. No association between the proportion of IBD patients at highest risk for COVID-19 complications and higher mortality rates was identified in different Brazilian states (r = 0.146, P = 0.467). CONCLUSION This study indicates a distinct geographical distribution of IBD patients at highest risk for COVID-19 complications in different states of the country, which may reflect contrasting socioeconomic, educational and healthcare aspects. No association between high risk of IBD and COVID-related mortality rates was identified.Department of Gastroenterology University of São Paulo School of MedicineIBD Unit Gastroenterology Department Gastrosaúde ClinicSchool of Medicine Federal University of BahiaIBD Outpatient Clinics Universidade Federal de Juiz de ForaHealth Sciences Postgraduate Program Pontifícia Universidade Católica do Paraná (PUCPR)Departamento de Ciências da Saúde Universidade do Oeste de Santa Catarina (UNOESC)Botucatu Medical School Paulista State University (UNESP)IBD Outpatient Clinics Pontificia Universidade Católica do Paraná (PUCPR)Botucatu Medical School Paulista State University (UNESP)Universidade de São Paulo (USP)Gastrosaúde ClinicUniversidade Federal da Bahia (UFBA)Universidade Federal de Juiz de ForaPontifícia Universidade Católica do Paraná (PUCPR)Universidade do Oeste de Santa Catarina (UNOESC)Universidade Estadual Paulista (Unesp)Pontificia Universidade Católica do Paraná (PUCPR)Queiroz, Natália Sousa FreitasTeixeira, Fábio VieiraMotta, Marina PamponetChebli, Liliana AndradeHino, Adriano Akira Ferreirade Almeida Martins, CamillaQuaresma, Abel Botelhode Paula da Silva, Alexandre AugustoDamião, Adérson Omar Mourão CintraSaad-Hossne, Rogerio [UNESP]Kotze, Paulo Gustavo2021-06-25T11:14:20Z2021-06-25T11:14:20Z2021-03-28info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1226-1239http://dx.doi.org/10.3748/wjg.v27.i12.1226World Journal of Gastroenterology, v. 27, n. 12, p. 1226-1239, 2021.2219-28401007-9327http://hdl.handle.net/11449/20856910.3748/wjg.v27.i12.12262-s2.0-85103775802Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengWorld Journal of Gastroenterologyinfo:eu-repo/semantics/openAccess2024-08-14T14:19:30Zoai:repositorio.unesp.br:11449/208569Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-14T14:19:30Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Risk stratification and geographical mapping of Brazilian inflammatory bowel disease patients during the COVID-19 outbreak: Results from a nationwide survey
title Risk stratification and geographical mapping of Brazilian inflammatory bowel disease patients during the COVID-19 outbreak: Results from a nationwide survey
spellingShingle Risk stratification and geographical mapping of Brazilian inflammatory bowel disease patients during the COVID-19 outbreak: Results from a nationwide survey
Queiroz, Natália Sousa Freitas
Brazil
Colitis
COVID-19
Crohn's disease
Inflammatory bowel disease
Ulcerative
title_short Risk stratification and geographical mapping of Brazilian inflammatory bowel disease patients during the COVID-19 outbreak: Results from a nationwide survey
title_full Risk stratification and geographical mapping of Brazilian inflammatory bowel disease patients during the COVID-19 outbreak: Results from a nationwide survey
title_fullStr Risk stratification and geographical mapping of Brazilian inflammatory bowel disease patients during the COVID-19 outbreak: Results from a nationwide survey
title_full_unstemmed Risk stratification and geographical mapping of Brazilian inflammatory bowel disease patients during the COVID-19 outbreak: Results from a nationwide survey
title_sort Risk stratification and geographical mapping of Brazilian inflammatory bowel disease patients during the COVID-19 outbreak: Results from a nationwide survey
author Queiroz, Natália Sousa Freitas
author_facet Queiroz, Natália Sousa Freitas
Teixeira, Fábio Vieira
Motta, Marina Pamponet
Chebli, Liliana Andrade
Hino, Adriano Akira Ferreira
de Almeida Martins, Camilla
Quaresma, Abel Botelho
de Paula da Silva, Alexandre Augusto
Damião, Adérson Omar Mourão Cintra
Saad-Hossne, Rogerio [UNESP]
Kotze, Paulo Gustavo
author_role author
author2 Teixeira, Fábio Vieira
Motta, Marina Pamponet
Chebli, Liliana Andrade
Hino, Adriano Akira Ferreira
de Almeida Martins, Camilla
Quaresma, Abel Botelho
de Paula da Silva, Alexandre Augusto
Damião, Adérson Omar Mourão Cintra
Saad-Hossne, Rogerio [UNESP]
Kotze, Paulo Gustavo
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade de São Paulo (USP)
Gastrosaúde Clinic
Universidade Federal da Bahia (UFBA)
Universidade Federal de Juiz de Fora
Pontifícia Universidade Católica do Paraná (PUCPR)
Universidade do Oeste de Santa Catarina (UNOESC)
Universidade Estadual Paulista (Unesp)
Pontificia Universidade Católica do Paraná (PUCPR)
dc.contributor.author.fl_str_mv Queiroz, Natália Sousa Freitas
Teixeira, Fábio Vieira
Motta, Marina Pamponet
Chebli, Liliana Andrade
Hino, Adriano Akira Ferreira
de Almeida Martins, Camilla
Quaresma, Abel Botelho
de Paula da Silva, Alexandre Augusto
Damião, Adérson Omar Mourão Cintra
Saad-Hossne, Rogerio [UNESP]
Kotze, Paulo Gustavo
dc.subject.por.fl_str_mv Brazil
Colitis
COVID-19
Crohn's disease
Inflammatory bowel disease
Ulcerative
topic Brazil
Colitis
COVID-19
Crohn's disease
Inflammatory bowel disease
Ulcerative
description BACKGROUND Coronavirus disease 2019 (COVID-19) pandemic is still evolving globally, and Brazil is currently one of the most affected countries. It is still debated whether patients with inflammatory bowel disease (IBD) are at a higher risk for developing COVID-19 or its complications. AIM To assess geographical distribution of IBD patients at the highest risk and correlate these data with COVID-19 mortality rates in Brazil. METHODS The Brazilian IBD Study Group (Grupo de Estudos da Doença Inflamatória Intestinal do Brasil) developed a web-based survey adapted from the British Society of Gastroenterology guidelines. The included categories were demographic data and inquiries related to risk factors for complications from COVID-19. Patients were categorized as highest, moderate or lowest individual risk. The Spearman correlation test was used to identify any association between highest risk and mortality rates for each state of the country. RESULTS A total of 3568 patients (65.3% females) were included. Most participants were from the southeastern and southern regions of Brazil, and 84.1% were using immunomodulators and/or biologics. Most patients (55.1%) were at moderate risk, 23.4% were at highest risk and 21.5% were at lowest risk of COVID-19 complications. No association between the proportion of IBD patients at highest risk for COVID-19 complications and higher mortality rates was identified in different Brazilian states (r = 0.146, P = 0.467). CONCLUSION This study indicates a distinct geographical distribution of IBD patients at highest risk for COVID-19 complications in different states of the country, which may reflect contrasting socioeconomic, educational and healthcare aspects. No association between high risk of IBD and COVID-related mortality rates was identified.
publishDate 2021
dc.date.none.fl_str_mv 2021-06-25T11:14:20Z
2021-06-25T11:14:20Z
2021-03-28
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.3748/wjg.v27.i12.1226
World Journal of Gastroenterology, v. 27, n. 12, p. 1226-1239, 2021.
2219-2840
1007-9327
http://hdl.handle.net/11449/208569
10.3748/wjg.v27.i12.1226
2-s2.0-85103775802
url http://dx.doi.org/10.3748/wjg.v27.i12.1226
http://hdl.handle.net/11449/208569
identifier_str_mv World Journal of Gastroenterology, v. 27, n. 12, p. 1226-1239, 2021.
2219-2840
1007-9327
10.3748/wjg.v27.i12.1226
2-s2.0-85103775802
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv World Journal of Gastroenterology
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1226-1239
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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