Risk stratification and geographical mapping of Brazilian inflammatory bowel disease patients during the COVID-19 outbreak: Results from a nationwide survey
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.3748/wjg.v27.i12.1226 http://hdl.handle.net/11449/208569 |
Resumo: | BACKGROUND Coronavirus disease 2019 (COVID-19) pandemic is still evolving globally, and Brazil is currently one of the most affected countries. It is still debated whether patients with inflammatory bowel disease (IBD) are at a higher risk for developing COVID-19 or its complications. AIM To assess geographical distribution of IBD patients at the highest risk and correlate these data with COVID-19 mortality rates in Brazil. METHODS The Brazilian IBD Study Group (Grupo de Estudos da Doença Inflamatória Intestinal do Brasil) developed a web-based survey adapted from the British Society of Gastroenterology guidelines. The included categories were demographic data and inquiries related to risk factors for complications from COVID-19. Patients were categorized as highest, moderate or lowest individual risk. The Spearman correlation test was used to identify any association between highest risk and mortality rates for each state of the country. RESULTS A total of 3568 patients (65.3% females) were included. Most participants were from the southeastern and southern regions of Brazil, and 84.1% were using immunomodulators and/or biologics. Most patients (55.1%) were at moderate risk, 23.4% were at highest risk and 21.5% were at lowest risk of COVID-19 complications. No association between the proportion of IBD patients at highest risk for COVID-19 complications and higher mortality rates was identified in different Brazilian states (r = 0.146, P = 0.467). CONCLUSION This study indicates a distinct geographical distribution of IBD patients at highest risk for COVID-19 complications in different states of the country, which may reflect contrasting socioeconomic, educational and healthcare aspects. No association between high risk of IBD and COVID-related mortality rates was identified. |
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Risk stratification and geographical mapping of Brazilian inflammatory bowel disease patients during the COVID-19 outbreak: Results from a nationwide surveyBrazilColitisCOVID-19Crohn's diseaseInflammatory bowel diseaseUlcerativeBACKGROUND Coronavirus disease 2019 (COVID-19) pandemic is still evolving globally, and Brazil is currently one of the most affected countries. It is still debated whether patients with inflammatory bowel disease (IBD) are at a higher risk for developing COVID-19 or its complications. AIM To assess geographical distribution of IBD patients at the highest risk and correlate these data with COVID-19 mortality rates in Brazil. METHODS The Brazilian IBD Study Group (Grupo de Estudos da Doença Inflamatória Intestinal do Brasil) developed a web-based survey adapted from the British Society of Gastroenterology guidelines. The included categories were demographic data and inquiries related to risk factors for complications from COVID-19. Patients were categorized as highest, moderate or lowest individual risk. The Spearman correlation test was used to identify any association between highest risk and mortality rates for each state of the country. RESULTS A total of 3568 patients (65.3% females) were included. Most participants were from the southeastern and southern regions of Brazil, and 84.1% were using immunomodulators and/or biologics. Most patients (55.1%) were at moderate risk, 23.4% were at highest risk and 21.5% were at lowest risk of COVID-19 complications. No association between the proportion of IBD patients at highest risk for COVID-19 complications and higher mortality rates was identified in different Brazilian states (r = 0.146, P = 0.467). CONCLUSION This study indicates a distinct geographical distribution of IBD patients at highest risk for COVID-19 complications in different states of the country, which may reflect contrasting socioeconomic, educational and healthcare aspects. No association between high risk of IBD and COVID-related mortality rates was identified.Department of Gastroenterology University of São Paulo School of MedicineIBD Unit Gastroenterology Department Gastrosaúde ClinicSchool of Medicine Federal University of BahiaIBD Outpatient Clinics Universidade Federal de Juiz de ForaHealth Sciences Postgraduate Program Pontifícia Universidade Católica do Paraná (PUCPR)Departamento de Ciências da Saúde Universidade do Oeste de Santa Catarina (UNOESC)Botucatu Medical School Paulista State University (UNESP)IBD Outpatient Clinics Pontificia Universidade Católica do Paraná (PUCPR)Botucatu Medical School Paulista State University (UNESP)Universidade de São Paulo (USP)Gastrosaúde ClinicUniversidade Federal da Bahia (UFBA)Universidade Federal de Juiz de ForaPontifícia Universidade Católica do Paraná (PUCPR)Universidade do Oeste de Santa Catarina (UNOESC)Universidade Estadual Paulista (Unesp)Pontificia Universidade Católica do Paraná (PUCPR)Queiroz, Natália Sousa FreitasTeixeira, Fábio VieiraMotta, Marina PamponetChebli, Liliana AndradeHino, Adriano Akira Ferreirade Almeida Martins, CamillaQuaresma, Abel Botelhode Paula da Silva, Alexandre AugustoDamião, Adérson Omar Mourão CintraSaad-Hossne, Rogerio [UNESP]Kotze, Paulo Gustavo2021-06-25T11:14:20Z2021-06-25T11:14:20Z2021-03-28info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1226-1239http://dx.doi.org/10.3748/wjg.v27.i12.1226World Journal of Gastroenterology, v. 27, n. 12, p. 1226-1239, 2021.2219-28401007-9327http://hdl.handle.net/11449/20856910.3748/wjg.v27.i12.12262-s2.0-85103775802Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengWorld Journal of Gastroenterologyinfo:eu-repo/semantics/openAccess2024-08-14T14:19:30Zoai:repositorio.unesp.br:11449/208569Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-14T14:19:30Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Risk stratification and geographical mapping of Brazilian inflammatory bowel disease patients during the COVID-19 outbreak: Results from a nationwide survey |
title |
Risk stratification and geographical mapping of Brazilian inflammatory bowel disease patients during the COVID-19 outbreak: Results from a nationwide survey |
spellingShingle |
Risk stratification and geographical mapping of Brazilian inflammatory bowel disease patients during the COVID-19 outbreak: Results from a nationwide survey Queiroz, Natália Sousa Freitas Brazil Colitis COVID-19 Crohn's disease Inflammatory bowel disease Ulcerative |
title_short |
Risk stratification and geographical mapping of Brazilian inflammatory bowel disease patients during the COVID-19 outbreak: Results from a nationwide survey |
title_full |
Risk stratification and geographical mapping of Brazilian inflammatory bowel disease patients during the COVID-19 outbreak: Results from a nationwide survey |
title_fullStr |
Risk stratification and geographical mapping of Brazilian inflammatory bowel disease patients during the COVID-19 outbreak: Results from a nationwide survey |
title_full_unstemmed |
Risk stratification and geographical mapping of Brazilian inflammatory bowel disease patients during the COVID-19 outbreak: Results from a nationwide survey |
title_sort |
Risk stratification and geographical mapping of Brazilian inflammatory bowel disease patients during the COVID-19 outbreak: Results from a nationwide survey |
author |
Queiroz, Natália Sousa Freitas |
author_facet |
Queiroz, Natália Sousa Freitas Teixeira, Fábio Vieira Motta, Marina Pamponet Chebli, Liliana Andrade Hino, Adriano Akira Ferreira de Almeida Martins, Camilla Quaresma, Abel Botelho de Paula da Silva, Alexandre Augusto Damião, Adérson Omar Mourão Cintra Saad-Hossne, Rogerio [UNESP] Kotze, Paulo Gustavo |
author_role |
author |
author2 |
Teixeira, Fábio Vieira Motta, Marina Pamponet Chebli, Liliana Andrade Hino, Adriano Akira Ferreira de Almeida Martins, Camilla Quaresma, Abel Botelho de Paula da Silva, Alexandre Augusto Damião, Adérson Omar Mourão Cintra Saad-Hossne, Rogerio [UNESP] Kotze, Paulo Gustavo |
author2_role |
author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade de São Paulo (USP) Gastrosaúde Clinic Universidade Federal da Bahia (UFBA) Universidade Federal de Juiz de Fora Pontifícia Universidade Católica do Paraná (PUCPR) Universidade do Oeste de Santa Catarina (UNOESC) Universidade Estadual Paulista (Unesp) Pontificia Universidade Católica do Paraná (PUCPR) |
dc.contributor.author.fl_str_mv |
Queiroz, Natália Sousa Freitas Teixeira, Fábio Vieira Motta, Marina Pamponet Chebli, Liliana Andrade Hino, Adriano Akira Ferreira de Almeida Martins, Camilla Quaresma, Abel Botelho de Paula da Silva, Alexandre Augusto Damião, Adérson Omar Mourão Cintra Saad-Hossne, Rogerio [UNESP] Kotze, Paulo Gustavo |
dc.subject.por.fl_str_mv |
Brazil Colitis COVID-19 Crohn's disease Inflammatory bowel disease Ulcerative |
topic |
Brazil Colitis COVID-19 Crohn's disease Inflammatory bowel disease Ulcerative |
description |
BACKGROUND Coronavirus disease 2019 (COVID-19) pandemic is still evolving globally, and Brazil is currently one of the most affected countries. It is still debated whether patients with inflammatory bowel disease (IBD) are at a higher risk for developing COVID-19 or its complications. AIM To assess geographical distribution of IBD patients at the highest risk and correlate these data with COVID-19 mortality rates in Brazil. METHODS The Brazilian IBD Study Group (Grupo de Estudos da Doença Inflamatória Intestinal do Brasil) developed a web-based survey adapted from the British Society of Gastroenterology guidelines. The included categories were demographic data and inquiries related to risk factors for complications from COVID-19. Patients were categorized as highest, moderate or lowest individual risk. The Spearman correlation test was used to identify any association between highest risk and mortality rates for each state of the country. RESULTS A total of 3568 patients (65.3% females) were included. Most participants were from the southeastern and southern regions of Brazil, and 84.1% were using immunomodulators and/or biologics. Most patients (55.1%) were at moderate risk, 23.4% were at highest risk and 21.5% were at lowest risk of COVID-19 complications. No association between the proportion of IBD patients at highest risk for COVID-19 complications and higher mortality rates was identified in different Brazilian states (r = 0.146, P = 0.467). CONCLUSION This study indicates a distinct geographical distribution of IBD patients at highest risk for COVID-19 complications in different states of the country, which may reflect contrasting socioeconomic, educational and healthcare aspects. No association between high risk of IBD and COVID-related mortality rates was identified. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-06-25T11:14:20Z 2021-06-25T11:14:20Z 2021-03-28 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.3748/wjg.v27.i12.1226 World Journal of Gastroenterology, v. 27, n. 12, p. 1226-1239, 2021. 2219-2840 1007-9327 http://hdl.handle.net/11449/208569 10.3748/wjg.v27.i12.1226 2-s2.0-85103775802 |
url |
http://dx.doi.org/10.3748/wjg.v27.i12.1226 http://hdl.handle.net/11449/208569 |
identifier_str_mv |
World Journal of Gastroenterology, v. 27, n. 12, p. 1226-1239, 2021. 2219-2840 1007-9327 10.3748/wjg.v27.i12.1226 2-s2.0-85103775802 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
World Journal of Gastroenterology |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
1226-1239 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
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1808128184769576960 |