Bone reformation and implant integration following maxillary sinus membrane elevation: An experimental study in primates
Autor(a) principal: | |
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Data de Publicação: | 2006 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.2310/j.6480.2005.00026.x http://hdl.handle.net/11449/68923 |
Resumo: | Background: Recent clinical studies have described maxillary sinus floor augmentation by simply elevating the maxillary sinus membrane without the use of adjunctive grafting materials. Purpose: This experimental study aimed at comparing the histologic outcomes of sinus membrane elevation and simultaneous placement of implants with and without adjunctive autogenous bone grafts. The purpose was also to investigate the role played by the implant surface in osseointegration under such circumstances. Materials and Methods: Four tufted capuchin primates had all upper premolars and the first molar extracted bilaterally. Four months later, the animals underwent maxillary sinus membrane elevation surgery using a replaceable bone window technique. The schneiderian membrane was kept elevated by insertion of two implants (turned and oxidized, Brånemark System®, Nobel Biocare AB, Göteborg, Sweden) in both sinuses. The right sinus was left with no additional treatment, whereas the left sinus was filled with autogenous bone graft. Implant stability was assessed through resonance frequency analysis (Osstell™, Integration Diagnostics AB, Göteborg, Sweden) at installation and at sacrifice. The pattern of bone formation in the experimental sites and related to the different implant surfaces was investigated using fluorochromes. The animals were sacrificed 6 months after the maxillary sinus floor augmentation procedure for histology and histomorphometry (bone-implant contact, bone area in threads, and bone area in rectangle). Results: The results showed no differences between membrane-elevated and grafted sites regarding implant stability, bone-implant contacts, and bone area within and outside implant threads. The oxidized implants exhibited improved integration compared with turned ones as higher values of bone-implant contact and bone area within threads were observed. Conclusions: The amount of augmented bone tissue in the maxillary sinus after sinus membrane elevation with or without adjunctive autogenous bone grafts does not differ after 6 months of healing. New bone is frequently deposited in contact with the schneiderian membrane in coagulum-alone sites, indicating the osteoinductive potential of the membrane. Oxidized implants show a stronger bone tissue response than turned implants in sinus floor augmentation procedures. © 2006 Blackwell Publishing, Inc. |
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Bone reformation and implant integration following maxillary sinus membrane elevation: An experimental study in primatesAugmentationBone formationDental implantsExperimental modelMaxillary sinusMembrane elevationOsseointegrationSurface treatmentsanimalbone regenerationbone transplantationCebidaecomparative studymalemaxillary sinusmembranemethodologysurface propertytooth implantationAnimalsBone TransplantationCebusDental Implantation, EndosseousMaleMaxillary SinusMembranesSurface PropertiesBackground: Recent clinical studies have described maxillary sinus floor augmentation by simply elevating the maxillary sinus membrane without the use of adjunctive grafting materials. Purpose: This experimental study aimed at comparing the histologic outcomes of sinus membrane elevation and simultaneous placement of implants with and without adjunctive autogenous bone grafts. The purpose was also to investigate the role played by the implant surface in osseointegration under such circumstances. Materials and Methods: Four tufted capuchin primates had all upper premolars and the first molar extracted bilaterally. Four months later, the animals underwent maxillary sinus membrane elevation surgery using a replaceable bone window technique. The schneiderian membrane was kept elevated by insertion of two implants (turned and oxidized, Brånemark System®, Nobel Biocare AB, Göteborg, Sweden) in both sinuses. The right sinus was left with no additional treatment, whereas the left sinus was filled with autogenous bone graft. Implant stability was assessed through resonance frequency analysis (Osstell™, Integration Diagnostics AB, Göteborg, Sweden) at installation and at sacrifice. The pattern of bone formation in the experimental sites and related to the different implant surfaces was investigated using fluorochromes. The animals were sacrificed 6 months after the maxillary sinus floor augmentation procedure for histology and histomorphometry (bone-implant contact, bone area in threads, and bone area in rectangle). Results: The results showed no differences between membrane-elevated and grafted sites regarding implant stability, bone-implant contacts, and bone area within and outside implant threads. The oxidized implants exhibited improved integration compared with turned ones as higher values of bone-implant contact and bone area within threads were observed. Conclusions: The amount of augmented bone tissue in the maxillary sinus after sinus membrane elevation with or without adjunctive autogenous bone grafts does not differ after 6 months of healing. New bone is frequently deposited in contact with the schneiderian membrane in coagulum-alone sites, indicating the osteoinductive potential of the membrane. Oxidized implants show a stronger bone tissue response than turned implants in sinus floor augmentation procedures. © 2006 Blackwell Publishing, Inc.Department of Oral and Maxillofacial Surgery University of the State of Sao Paulo Faculty of Dentistry of AracatubaDepartment of Basic Sciences University of the State of Sao Paulo Faculty of Dentistry of AracatubaDepartment of Oral and Maxillofacial Surgery Umeå University, UmeåDepartment of Oral and Maxillofacial Surgery and Periodontics University of Sao Paulo Faculty of Dentistry of Ribeirao PretoDepartment of Biomaterials Sahlgrenska Academy Göteborg University, GöteborgDepartment of Biomaterials Sahlgrenska Academy Göteborg University, PO Box 412, SE 405 30 GöteborgUniversidade Estadual Paulista (Unesp)Umeå UniversityUniversidade de São Paulo (USP)Göteborg UniversityPalma, Vinicius C.Magro Filho, Osvaldo [UNESP]Oliveira, José Américo de [UNESP]Lundgren, StefanSalata, Luiz A.Sennerby, Lars2014-05-27T11:21:53Z2014-05-27T11:21:53Z2006-06-14info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article11-24http://dx.doi.org/10.2310/j.6480.2005.00026.xClinical Implant Dentistry and Related Research, v. 8, n. 1, p. 11-24, 2006.1523-0899http://hdl.handle.net/11449/6892310.2310/j.6480.2005.00026.x2-s2.0-3374490832455354186707451256273648007883637Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengClinical Implant Dentistry and Related Research3.0971,827info:eu-repo/semantics/openAccess2021-10-23T10:49:32Zoai:repositorio.unesp.br:11449/68923Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T14:41:14.199181Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Bone reformation and implant integration following maxillary sinus membrane elevation: An experimental study in primates |
title |
Bone reformation and implant integration following maxillary sinus membrane elevation: An experimental study in primates |
spellingShingle |
Bone reformation and implant integration following maxillary sinus membrane elevation: An experimental study in primates Palma, Vinicius C. Augmentation Bone formation Dental implants Experimental model Maxillary sinus Membrane elevation Osseointegration Surface treatments animal bone regeneration bone transplantation Cebidae comparative study male maxillary sinus membrane methodology surface property tooth implantation Animals Bone Transplantation Cebus Dental Implantation, Endosseous Male Maxillary Sinus Membranes Surface Properties |
title_short |
Bone reformation and implant integration following maxillary sinus membrane elevation: An experimental study in primates |
title_full |
Bone reformation and implant integration following maxillary sinus membrane elevation: An experimental study in primates |
title_fullStr |
Bone reformation and implant integration following maxillary sinus membrane elevation: An experimental study in primates |
title_full_unstemmed |
Bone reformation and implant integration following maxillary sinus membrane elevation: An experimental study in primates |
title_sort |
Bone reformation and implant integration following maxillary sinus membrane elevation: An experimental study in primates |
author |
Palma, Vinicius C. |
author_facet |
Palma, Vinicius C. Magro Filho, Osvaldo [UNESP] Oliveira, José Américo de [UNESP] Lundgren, Stefan Salata, Luiz A. Sennerby, Lars |
author_role |
author |
author2 |
Magro Filho, Osvaldo [UNESP] Oliveira, José Américo de [UNESP] Lundgren, Stefan Salata, Luiz A. Sennerby, Lars |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Umeå University Universidade de São Paulo (USP) Göteborg University |
dc.contributor.author.fl_str_mv |
Palma, Vinicius C. Magro Filho, Osvaldo [UNESP] Oliveira, José Américo de [UNESP] Lundgren, Stefan Salata, Luiz A. Sennerby, Lars |
dc.subject.por.fl_str_mv |
Augmentation Bone formation Dental implants Experimental model Maxillary sinus Membrane elevation Osseointegration Surface treatments animal bone regeneration bone transplantation Cebidae comparative study male maxillary sinus membrane methodology surface property tooth implantation Animals Bone Transplantation Cebus Dental Implantation, Endosseous Male Maxillary Sinus Membranes Surface Properties |
topic |
Augmentation Bone formation Dental implants Experimental model Maxillary sinus Membrane elevation Osseointegration Surface treatments animal bone regeneration bone transplantation Cebidae comparative study male maxillary sinus membrane methodology surface property tooth implantation Animals Bone Transplantation Cebus Dental Implantation, Endosseous Male Maxillary Sinus Membranes Surface Properties |
description |
Background: Recent clinical studies have described maxillary sinus floor augmentation by simply elevating the maxillary sinus membrane without the use of adjunctive grafting materials. Purpose: This experimental study aimed at comparing the histologic outcomes of sinus membrane elevation and simultaneous placement of implants with and without adjunctive autogenous bone grafts. The purpose was also to investigate the role played by the implant surface in osseointegration under such circumstances. Materials and Methods: Four tufted capuchin primates had all upper premolars and the first molar extracted bilaterally. Four months later, the animals underwent maxillary sinus membrane elevation surgery using a replaceable bone window technique. The schneiderian membrane was kept elevated by insertion of two implants (turned and oxidized, Brånemark System®, Nobel Biocare AB, Göteborg, Sweden) in both sinuses. The right sinus was left with no additional treatment, whereas the left sinus was filled with autogenous bone graft. Implant stability was assessed through resonance frequency analysis (Osstell™, Integration Diagnostics AB, Göteborg, Sweden) at installation and at sacrifice. The pattern of bone formation in the experimental sites and related to the different implant surfaces was investigated using fluorochromes. The animals were sacrificed 6 months after the maxillary sinus floor augmentation procedure for histology and histomorphometry (bone-implant contact, bone area in threads, and bone area in rectangle). Results: The results showed no differences between membrane-elevated and grafted sites regarding implant stability, bone-implant contacts, and bone area within and outside implant threads. The oxidized implants exhibited improved integration compared with turned ones as higher values of bone-implant contact and bone area within threads were observed. Conclusions: The amount of augmented bone tissue in the maxillary sinus after sinus membrane elevation with or without adjunctive autogenous bone grafts does not differ after 6 months of healing. New bone is frequently deposited in contact with the schneiderian membrane in coagulum-alone sites, indicating the osteoinductive potential of the membrane. Oxidized implants show a stronger bone tissue response than turned implants in sinus floor augmentation procedures. © 2006 Blackwell Publishing, Inc. |
publishDate |
2006 |
dc.date.none.fl_str_mv |
2006-06-14 2014-05-27T11:21:53Z 2014-05-27T11:21:53Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.2310/j.6480.2005.00026.x Clinical Implant Dentistry and Related Research, v. 8, n. 1, p. 11-24, 2006. 1523-0899 http://hdl.handle.net/11449/68923 10.2310/j.6480.2005.00026.x 2-s2.0-33744908324 5535418670745125 6273648007883637 |
url |
http://dx.doi.org/10.2310/j.6480.2005.00026.x http://hdl.handle.net/11449/68923 |
identifier_str_mv |
Clinical Implant Dentistry and Related Research, v. 8, n. 1, p. 11-24, 2006. 1523-0899 10.2310/j.6480.2005.00026.x 2-s2.0-33744908324 5535418670745125 6273648007883637 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Clinical Implant Dentistry and Related Research 3.097 1,827 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
11-24 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
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1808128401733582848 |