Verificação da atividade antibacteriana de sabonete líquido contendo extrato glicólico de Dimorphandra mollis Benth.
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://serv-bib.fcfar.unesp.br/seer/index.php/Cien_Farm/article/view/1072 http://hdl.handle.net/11449/70998 |
Resumo: | Dimorphandra mollis Benth., Compositae, false barbatimão, has been used topically as a healing, astringent and antibacterial. In this study, antibacterial activity was verified on liquid soap containing glycolic extract of D. mollis (DGE) at different concentrations (8, 15 and 20%) and at different pH levels (6 and 8). Five soap formulations (F) were prepared: F1 - tryclosan (0.1%), F2 - DGE (8%), F3 - DGE (15%), F4 - DGE (20%) and F5 - without preservatives. Bark of D. mollis were dried in a circulating air oven and ground. The rude extracts were prepared by turbo extraction with ethanol. After screening, the extract were concentrated in rotating evaporator, lyophilized and resuspended in propileneglycol to obtain the glycolic extract. The antimicrobial activity was verified by diffusion in agar method, using cylinder in plate. Plates containing Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli were incubated at 37°C for 24 hours. After incubation, the results were analysed with a pachymeter, observing the bacterial grouth inhibition halo diameter. It was verified that the liquid soap containing tryclosan caused on inhibition of bacterial growth at both pH levels; the soaps without preservatives and containing DGE, independently of the concentration and pH levels used, did not present antibacterial activity. |
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spelling |
Verificação da atividade antibacteriana de sabonete líquido contendo extrato glicólico de Dimorphandra mollis Benth.Verification of the antibacterial activity of liquid soap containing glycolic extract of Dimorphandra mollis Benth.Antibacterial activityDimorphandra mollis Benth.Liquid soapantiinfective agentdimorphandra mollis extractglycolic acidplant extractpreservativesoapunclassified drugagar diffusionantibacterial activitybacterial growthbarkconcentration (parameters)dimorphandra mollisdrug inhibitionEscherichia coligrowth inhibitionincubation temperaturemedicinal plantnonhumanpHPseudomonas aeruginosaStaphylococcus aureusDimorphandra mollis Benth., Compositae, false barbatimão, has been used topically as a healing, astringent and antibacterial. In this study, antibacterial activity was verified on liquid soap containing glycolic extract of D. mollis (DGE) at different concentrations (8, 15 and 20%) and at different pH levels (6 and 8). Five soap formulations (F) were prepared: F1 - tryclosan (0.1%), F2 - DGE (8%), F3 - DGE (15%), F4 - DGE (20%) and F5 - without preservatives. Bark of D. mollis were dried in a circulating air oven and ground. The rude extracts were prepared by turbo extraction with ethanol. After screening, the extract were concentrated in rotating evaporator, lyophilized and resuspended in propileneglycol to obtain the glycolic extract. The antimicrobial activity was verified by diffusion in agar method, using cylinder in plate. Plates containing Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli were incubated at 37°C for 24 hours. After incubation, the results were analysed with a pachymeter, observing the bacterial grouth inhibition halo diameter. It was verified that the liquid soap containing tryclosan caused on inhibition of bacterial growth at both pH levels; the soaps without preservatives and containing DGE, independently of the concentration and pH levels used, did not present antibacterial activity.Departamento de Fármacos e Medicamentos Faculdade de Ciências Farmacêuticas de Araraquara UNESP, Rodovia Araraquara-Jaú, km 1, CEP: 14801-902 - Araraquara - SPDepartamento de Princípios Ativos Naturais e Toxicologia Faculdade de Ciências Farmacêuticas Universidade Estadual Paulista, UNESP, Araraquara, SPDepartamento de Fármacos e Medicamentos Faculdade de Ciências Farmacêuticas de Araraquara UNESP, Rodovia Araraquara-Jaú, km 1, CEP: 14801-902 - Araraquara - SPDepartamento de Princípios Ativos Naturais e Toxicologia Faculdade de Ciências Farmacêuticas Universidade Estadual Paulista, UNESP, Araraquara, SPUniversidade Estadual Paulista (Unesp)Migliato, K. F. [UNESP]Chorilli, Marlus [UNESP]Scarpa, M. V. [UNESP]Moreira, Raquel Regina Duarte [UNESP]Correa, Marcos Antonio [UNESP]Isaac, Vera Lucia Borges [UNESP]Salgado, Hérida Regina Nunes [UNESP]2014-05-27T11:23:54Z2014-05-27T11:23:54Z2009-05-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article197-202application/pdfhttp://serv-bib.fcfar.unesp.br/seer/index.php/Cien_Farm/article/view/1072Revista de Ciencias Farmaceuticas Basica e Aplicada, v. 30, n. 2, p. 197-202, 2009.1808-45322179-443Xhttp://hdl.handle.net/11449/709982-s2.0-786498964592-s2.0-78649896459.pdf33160116888299434842462513285606142712599671628277103444618649240000-0002-4253-0320Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporRevista de Ciências Farmacêuticas Básica e Aplicada0,131info:eu-repo/semantics/openAccess2024-06-24T14:51:40Zoai:repositorio.unesp.br:11449/70998Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T16:45:25.756653Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Verificação da atividade antibacteriana de sabonete líquido contendo extrato glicólico de Dimorphandra mollis Benth. Verification of the antibacterial activity of liquid soap containing glycolic extract of Dimorphandra mollis Benth. |
title |
Verificação da atividade antibacteriana de sabonete líquido contendo extrato glicólico de Dimorphandra mollis Benth. |
spellingShingle |
Verificação da atividade antibacteriana de sabonete líquido contendo extrato glicólico de Dimorphandra mollis Benth. Migliato, K. F. [UNESP] Antibacterial activity Dimorphandra mollis Benth. Liquid soap antiinfective agent dimorphandra mollis extract glycolic acid plant extract preservative soap unclassified drug agar diffusion antibacterial activity bacterial growth bark concentration (parameters) dimorphandra mollis drug inhibition Escherichia coli growth inhibition incubation temperature medicinal plant nonhuman pH Pseudomonas aeruginosa Staphylococcus aureus |
title_short |
Verificação da atividade antibacteriana de sabonete líquido contendo extrato glicólico de Dimorphandra mollis Benth. |
title_full |
Verificação da atividade antibacteriana de sabonete líquido contendo extrato glicólico de Dimorphandra mollis Benth. |
title_fullStr |
Verificação da atividade antibacteriana de sabonete líquido contendo extrato glicólico de Dimorphandra mollis Benth. |
title_full_unstemmed |
Verificação da atividade antibacteriana de sabonete líquido contendo extrato glicólico de Dimorphandra mollis Benth. |
title_sort |
Verificação da atividade antibacteriana de sabonete líquido contendo extrato glicólico de Dimorphandra mollis Benth. |
author |
Migliato, K. F. [UNESP] |
author_facet |
Migliato, K. F. [UNESP] Chorilli, Marlus [UNESP] Scarpa, M. V. [UNESP] Moreira, Raquel Regina Duarte [UNESP] Correa, Marcos Antonio [UNESP] Isaac, Vera Lucia Borges [UNESP] Salgado, Hérida Regina Nunes [UNESP] |
author_role |
author |
author2 |
Chorilli, Marlus [UNESP] Scarpa, M. V. [UNESP] Moreira, Raquel Regina Duarte [UNESP] Correa, Marcos Antonio [UNESP] Isaac, Vera Lucia Borges [UNESP] Salgado, Hérida Regina Nunes [UNESP] |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Migliato, K. F. [UNESP] Chorilli, Marlus [UNESP] Scarpa, M. V. [UNESP] Moreira, Raquel Regina Duarte [UNESP] Correa, Marcos Antonio [UNESP] Isaac, Vera Lucia Borges [UNESP] Salgado, Hérida Regina Nunes [UNESP] |
dc.subject.por.fl_str_mv |
Antibacterial activity Dimorphandra mollis Benth. Liquid soap antiinfective agent dimorphandra mollis extract glycolic acid plant extract preservative soap unclassified drug agar diffusion antibacterial activity bacterial growth bark concentration (parameters) dimorphandra mollis drug inhibition Escherichia coli growth inhibition incubation temperature medicinal plant nonhuman pH Pseudomonas aeruginosa Staphylococcus aureus |
topic |
Antibacterial activity Dimorphandra mollis Benth. Liquid soap antiinfective agent dimorphandra mollis extract glycolic acid plant extract preservative soap unclassified drug agar diffusion antibacterial activity bacterial growth bark concentration (parameters) dimorphandra mollis drug inhibition Escherichia coli growth inhibition incubation temperature medicinal plant nonhuman pH Pseudomonas aeruginosa Staphylococcus aureus |
description |
Dimorphandra mollis Benth., Compositae, false barbatimão, has been used topically as a healing, astringent and antibacterial. In this study, antibacterial activity was verified on liquid soap containing glycolic extract of D. mollis (DGE) at different concentrations (8, 15 and 20%) and at different pH levels (6 and 8). Five soap formulations (F) were prepared: F1 - tryclosan (0.1%), F2 - DGE (8%), F3 - DGE (15%), F4 - DGE (20%) and F5 - without preservatives. Bark of D. mollis were dried in a circulating air oven and ground. The rude extracts were prepared by turbo extraction with ethanol. After screening, the extract were concentrated in rotating evaporator, lyophilized and resuspended in propileneglycol to obtain the glycolic extract. The antimicrobial activity was verified by diffusion in agar method, using cylinder in plate. Plates containing Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli were incubated at 37°C for 24 hours. After incubation, the results were analysed with a pachymeter, observing the bacterial grouth inhibition halo diameter. It was verified that the liquid soap containing tryclosan caused on inhibition of bacterial growth at both pH levels; the soaps without preservatives and containing DGE, independently of the concentration and pH levels used, did not present antibacterial activity. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-05-01 2014-05-27T11:23:54Z 2014-05-27T11:23:54Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://serv-bib.fcfar.unesp.br/seer/index.php/Cien_Farm/article/view/1072 Revista de Ciencias Farmaceuticas Basica e Aplicada, v. 30, n. 2, p. 197-202, 2009. 1808-4532 2179-443X http://hdl.handle.net/11449/70998 2-s2.0-78649896459 2-s2.0-78649896459.pdf 3316011688829943 4842462513285606 1427125996716282 7710344461864924 0000-0002-4253-0320 |
url |
http://serv-bib.fcfar.unesp.br/seer/index.php/Cien_Farm/article/view/1072 http://hdl.handle.net/11449/70998 |
identifier_str_mv |
Revista de Ciencias Farmaceuticas Basica e Aplicada, v. 30, n. 2, p. 197-202, 2009. 1808-4532 2179-443X 2-s2.0-78649896459 2-s2.0-78649896459.pdf 3316011688829943 4842462513285606 1427125996716282 7710344461864924 0000-0002-4253-0320 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
Revista de Ciências Farmacêuticas Básica e Aplicada 0,131 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
197-202 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
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1808128697097519104 |