Influence of cognitive impairment on the freezing of gait in non demented people with Parkinson’s disease
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.33588/rn.6609.2017289 http://hdl.handle.net/11449/228541 |
Resumo: | Introduction. Freezing of gait (FOG) is a motor disturbance usually appearing in advanced Parkinson’s disease (PD). Cognitive and executive function seems to play an important role in this phenomenon. Aim. To investigate if cognitive and kinematic parameters correlate with FOG in PD patients without dementia. Patients and methods. We conducted an observational cross-sectional study. Participants were classified in two groups: freezers and non-freezers. Clinical information was obtained by Hoehn & Yahr scale, Unified Parkinson’s Disease Rating Scale and balance test of Short Physical Performance Battery. Cognitive function was evaluated using Minimental Examination and the Fuld Object Memory Evaluation; executive function was assessed with the Frontal Assessment Battery test. Battery kinematic parameters were assessed by means of gait speed, cadence, stride length and stride time. Results. Twenty-five participants with PD without dementia completed the evaluation. Statistical significant differences between freezers and non-freezers were found in global cognition (p = 0.02), memory (p = 0.04), executive function (p = 0.04), cadence (p = 0.02), stride length (p = 0.04) and stride time (p = 0.01). Conclusion. Cognitive parameters may have an important contribution to the manifestation of freezing of gait in PD. These results may have important clinical implications for developing future non-pharmacological and cognitive interventions strategies targeted to PD patients with FOG. |
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Influence of cognitive impairment on the freezing of gait in non demented people with Parkinson’s diseaseInfluencia del deterioro cognitivo en la congelación de la marcha en pacientes con enfermedad de Parkinson sin demenciaCognitionGaitMotor disturbanceOlder peopleParkinson’s diseaseIntroduction. Freezing of gait (FOG) is a motor disturbance usually appearing in advanced Parkinson’s disease (PD). Cognitive and executive function seems to play an important role in this phenomenon. Aim. To investigate if cognitive and kinematic parameters correlate with FOG in PD patients without dementia. Patients and methods. We conducted an observational cross-sectional study. Participants were classified in two groups: freezers and non-freezers. Clinical information was obtained by Hoehn & Yahr scale, Unified Parkinson’s Disease Rating Scale and balance test of Short Physical Performance Battery. Cognitive function was evaluated using Minimental Examination and the Fuld Object Memory Evaluation; executive function was assessed with the Frontal Assessment Battery test. Battery kinematic parameters were assessed by means of gait speed, cadence, stride length and stride time. Results. Twenty-five participants with PD without dementia completed the evaluation. Statistical significant differences between freezers and non-freezers were found in global cognition (p = 0.02), memory (p = 0.04), executive function (p = 0.04), cadence (p = 0.02), stride length (p = 0.04) and stride time (p = 0.01). Conclusion. Cognitive parameters may have an important contribution to the manifestation of freezing of gait in PD. These results may have important clinical implications for developing future non-pharmacological and cognitive interventions strategies targeted to PD patients with FOG.Laboratório de Envelhecimento e Atividade Física Departamento de Educação Física Campus Rio Claro Universidade Estadual PaulistaGerontology Research Group Department of Medicine Faculty of Health Sciences University of A CoruñaDepartment of Special Didactics University of VigoNeurology Department Complexo Hospitalario Pontevedra-SalnésHealthyFit Research Group Galicia Sur Health Research Institute SERGAS-UVIGOLaboratório de Envelhecimento e Atividade Física Departamento de Educação Física Campus Rio Claro Universidade Estadual PaulistaUniversidade Estadual Paulista (UNESP)University of A CoruñaUniversity of VigoComplexo Hospitalario Pontevedra-SalnésSERGAS-UVIGOCancela, José M.Nascimento, Carla M. [UNESP]Varela, SilviaSeijo-Martínez, ManuelLorenzo-López, LauraMillán-Calenti, José C.Domínguez-Vivero, ClaraAyán, Carlos2022-04-29T08:27:19Z2022-04-29T08:27:19Z2018-05-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article289-296http://dx.doi.org/10.33588/rn.6609.2017289Revista de Neurologia, v. 66, n. 9, p. 289-296, 2018.0210-0010http://hdl.handle.net/11449/22854110.33588/rn.6609.20172892-s2.0-85046708280Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengRevista de Neurologiainfo:eu-repo/semantics/openAccess2022-04-29T08:27:19Zoai:repositorio.unesp.br:11449/228541Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462022-04-29T08:27:19Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Influence of cognitive impairment on the freezing of gait in non demented people with Parkinson’s disease Influencia del deterioro cognitivo en la congelación de la marcha en pacientes con enfermedad de Parkinson sin demencia |
title |
Influence of cognitive impairment on the freezing of gait in non demented people with Parkinson’s disease |
spellingShingle |
Influence of cognitive impairment on the freezing of gait in non demented people with Parkinson’s disease Cancela, José M. Cognition Gait Motor disturbance Older people Parkinson’s disease |
title_short |
Influence of cognitive impairment on the freezing of gait in non demented people with Parkinson’s disease |
title_full |
Influence of cognitive impairment on the freezing of gait in non demented people with Parkinson’s disease |
title_fullStr |
Influence of cognitive impairment on the freezing of gait in non demented people with Parkinson’s disease |
title_full_unstemmed |
Influence of cognitive impairment on the freezing of gait in non demented people with Parkinson’s disease |
title_sort |
Influence of cognitive impairment on the freezing of gait in non demented people with Parkinson’s disease |
author |
Cancela, José M. |
author_facet |
Cancela, José M. Nascimento, Carla M. [UNESP] Varela, Silvia Seijo-Martínez, Manuel Lorenzo-López, Laura Millán-Calenti, José C. Domínguez-Vivero, Clara Ayán, Carlos |
author_role |
author |
author2 |
Nascimento, Carla M. [UNESP] Varela, Silvia Seijo-Martínez, Manuel Lorenzo-López, Laura Millán-Calenti, José C. Domínguez-Vivero, Clara Ayán, Carlos |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) University of A Coruña University of Vigo Complexo Hospitalario Pontevedra-Salnés SERGAS-UVIGO |
dc.contributor.author.fl_str_mv |
Cancela, José M. Nascimento, Carla M. [UNESP] Varela, Silvia Seijo-Martínez, Manuel Lorenzo-López, Laura Millán-Calenti, José C. Domínguez-Vivero, Clara Ayán, Carlos |
dc.subject.por.fl_str_mv |
Cognition Gait Motor disturbance Older people Parkinson’s disease |
topic |
Cognition Gait Motor disturbance Older people Parkinson’s disease |
description |
Introduction. Freezing of gait (FOG) is a motor disturbance usually appearing in advanced Parkinson’s disease (PD). Cognitive and executive function seems to play an important role in this phenomenon. Aim. To investigate if cognitive and kinematic parameters correlate with FOG in PD patients without dementia. Patients and methods. We conducted an observational cross-sectional study. Participants were classified in two groups: freezers and non-freezers. Clinical information was obtained by Hoehn & Yahr scale, Unified Parkinson’s Disease Rating Scale and balance test of Short Physical Performance Battery. Cognitive function was evaluated using Minimental Examination and the Fuld Object Memory Evaluation; executive function was assessed with the Frontal Assessment Battery test. Battery kinematic parameters were assessed by means of gait speed, cadence, stride length and stride time. Results. Twenty-five participants with PD without dementia completed the evaluation. Statistical significant differences between freezers and non-freezers were found in global cognition (p = 0.02), memory (p = 0.04), executive function (p = 0.04), cadence (p = 0.02), stride length (p = 0.04) and stride time (p = 0.01). Conclusion. Cognitive parameters may have an important contribution to the manifestation of freezing of gait in PD. These results may have important clinical implications for developing future non-pharmacological and cognitive interventions strategies targeted to PD patients with FOG. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-05-01 2022-04-29T08:27:19Z 2022-04-29T08:27:19Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.33588/rn.6609.2017289 Revista de Neurologia, v. 66, n. 9, p. 289-296, 2018. 0210-0010 http://hdl.handle.net/11449/228541 10.33588/rn.6609.2017289 2-s2.0-85046708280 |
url |
http://dx.doi.org/10.33588/rn.6609.2017289 http://hdl.handle.net/11449/228541 |
identifier_str_mv |
Revista de Neurologia, v. 66, n. 9, p. 289-296, 2018. 0210-0010 10.33588/rn.6609.2017289 2-s2.0-85046708280 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Revista de Neurologia |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
289-296 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1803046926522777600 |