SISTER CHROMATID EXCHANGES IN HETEROZYGOTE BETA-THALASSEMIC PATIENTS WITH NORMAL FOLATE LEVELS

Detalhes bibliográficos
Autor(a) principal: Silva, A. E.
Data de Publicação: 1993
Outros Autores: Manzato, A. J., Varellagarcia, M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://www.gmb.org.br/Revistas/V16/v16a019.pdf
http://hdl.handle.net/11449/38132
Resumo: Lymphocytes from beta thalassaemia heterozygote patients, with normal levels of plasma folic acid cultured for 72 h in a folate rich medium, were not found to contain increased rates of sister chromatid exchanges (SCE). A wide intra and interindividual variability was found in both thalassaemic and control groups and methodological and biological factors, such as types of peripheral lymphocytes, sex, age, and smoking, alcohol and coffee drinking, as well as dietary habits, are possibly responsible for these variations.
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spelling SISTER CHROMATID EXCHANGES IN HETEROZYGOTE BETA-THALASSEMIC PATIENTS WITH NORMAL FOLATE LEVELSLymphocytes from beta thalassaemia heterozygote patients, with normal levels of plasma folic acid cultured for 72 h in a folate rich medium, were not found to contain increased rates of sister chromatid exchanges (SCE). A wide intra and interindividual variability was found in both thalassaemic and control groups and methodological and biological factors, such as types of peripheral lymphocytes, sex, age, and smoking, alcohol and coffee drinking, as well as dietary habits, are possibly responsible for these variations.UNESP,LETRAS & CIENCIAS EXATAS,INST BIOCIENCIAS,DEPT BIOL,BR-15054 S JOSE RIO P,SP,BRAZILUNESP,LETRAS & CIENCIAS EXATAS,INST BIOCIENCIAS,DEPT BIOL,BR-15054 S JOSE RIO P,SP,BRAZILSoc Brasil GeneticaUniversidade Estadual Paulista (Unesp)Silva, A. E.Manzato, A. J.Varellagarcia, M.2014-05-20T15:28:18Z2014-05-20T15:28:18Z1993-03-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article203-210application/pdfhttp://www.gmb.org.br/Revistas/V16/v16a019.pdfRevista Brasileira de Genetica. Ribeirao Pret: Soc Brasil Genetica, v. 16, n. 1, p. 203-210, 1993.0100-8455http://hdl.handle.net/11449/38132WOS:A1993KU77900019WOSA1993KU77900019.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengRevista Brasileira de Genéticainfo:eu-repo/semantics/openAccess2023-10-21T06:10:04Zoai:repositorio.unesp.br:11449/38132Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T15:33:13.995371Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv SISTER CHROMATID EXCHANGES IN HETEROZYGOTE BETA-THALASSEMIC PATIENTS WITH NORMAL FOLATE LEVELS
title SISTER CHROMATID EXCHANGES IN HETEROZYGOTE BETA-THALASSEMIC PATIENTS WITH NORMAL FOLATE LEVELS
spellingShingle SISTER CHROMATID EXCHANGES IN HETEROZYGOTE BETA-THALASSEMIC PATIENTS WITH NORMAL FOLATE LEVELS
Silva, A. E.
title_short SISTER CHROMATID EXCHANGES IN HETEROZYGOTE BETA-THALASSEMIC PATIENTS WITH NORMAL FOLATE LEVELS
title_full SISTER CHROMATID EXCHANGES IN HETEROZYGOTE BETA-THALASSEMIC PATIENTS WITH NORMAL FOLATE LEVELS
title_fullStr SISTER CHROMATID EXCHANGES IN HETEROZYGOTE BETA-THALASSEMIC PATIENTS WITH NORMAL FOLATE LEVELS
title_full_unstemmed SISTER CHROMATID EXCHANGES IN HETEROZYGOTE BETA-THALASSEMIC PATIENTS WITH NORMAL FOLATE LEVELS
title_sort SISTER CHROMATID EXCHANGES IN HETEROZYGOTE BETA-THALASSEMIC PATIENTS WITH NORMAL FOLATE LEVELS
author Silva, A. E.
author_facet Silva, A. E.
Manzato, A. J.
Varellagarcia, M.
author_role author
author2 Manzato, A. J.
Varellagarcia, M.
author2_role author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Silva, A. E.
Manzato, A. J.
Varellagarcia, M.
description Lymphocytes from beta thalassaemia heterozygote patients, with normal levels of plasma folic acid cultured for 72 h in a folate rich medium, were not found to contain increased rates of sister chromatid exchanges (SCE). A wide intra and interindividual variability was found in both thalassaemic and control groups and methodological and biological factors, such as types of peripheral lymphocytes, sex, age, and smoking, alcohol and coffee drinking, as well as dietary habits, are possibly responsible for these variations.
publishDate 1993
dc.date.none.fl_str_mv 1993-03-01
2014-05-20T15:28:18Z
2014-05-20T15:28:18Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.gmb.org.br/Revistas/V16/v16a019.pdf
Revista Brasileira de Genetica. Ribeirao Pret: Soc Brasil Genetica, v. 16, n. 1, p. 203-210, 1993.
0100-8455
http://hdl.handle.net/11449/38132
WOS:A1993KU77900019
WOSA1993KU77900019.pdf
url http://www.gmb.org.br/Revistas/V16/v16a019.pdf
http://hdl.handle.net/11449/38132
identifier_str_mv Revista Brasileira de Genetica. Ribeirao Pret: Soc Brasil Genetica, v. 16, n. 1, p. 203-210, 1993.
0100-8455
WOS:A1993KU77900019
WOSA1993KU77900019.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Revista Brasileira de Genética
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 203-210
application/pdf
dc.publisher.none.fl_str_mv Soc Brasil Genetica
publisher.none.fl_str_mv Soc Brasil Genetica
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808128530860474368

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